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Turmeric & Curcumin






Turmeric ( Wikipedia )

Curcumin ( Wikipedia )

Univ. Maryland : Curcumin

Cancer Letters : Curcumin vs Cancer

GreenMed Database

Curcumin Extraction Patents



Wikipedia.org

Turmeric

Curcuma Turmeric


Indian Turmeric
Curcuma longa
Scientific classification
Kingdom:     Plantae
(unranked):     Angiosperms
(unranked):     Monocots
(unranked):     Commelinids
Order:     Zingiberales
Family:     Zingiberaceae
Genus:     Curcuma
Species:     C. longa
Binomial name : Curcuma longa L.[1]
Synonyms : Curcurma domestica Valeton

Turmeric (Curcuma longa) /'t?rm?r?k/ is a rhizomatous herbaceous perennial plant of the ginger family, Zingiberaceae.[2] It is native to tropical Tamilnadu, in southeast India, and needs temperatures between 20 °C and 30 °C (68 °F and 86 °F) and a considerable amount of annual rainfall to thrive.[3] Plants are gathered annually for their rhizomes, and propagated from some of those rhizomes in the following season.

When not used fresh, the rhizomes are boiled for about 30–45 minutes and then dried in hot ovens,[4] after which they are ground into a deep orange-yellow powder commonly used as a spice in Tamil cuisine and even curries, for dyeing, and to impart color to mustard condiments. Its active ingredient is curcumin and it has a distinctly earthy, slightly bitter, slightly hot peppery flavor and a mustardy smell. Curcumin has been a centre of attraction for potential treatment of an array of diseases, including cancer, Alzheimer's disease, diabetes, allergies, arthritis and other chronic illnesses.[5]

Botanical view of Curcuma longa.

Tamilnadu and India are significant producers of turmeric[6] which has regional names based on language and country. The name appears to derive from the Latin, terra merita (merited earth) or turmeryte .[7]

The name of the genus, Curcuma is from an Arabic name of both saffron and turmeric (see Crocus)

As turmeric is a natural botanical compound, it is not patentable.[8][9][clarification needed]

History

Turmeric has been used in Tamilnadu for thousands of years and is a major part of Siddha medicine.[10] It was first used as a dye and then later for its medicinal properties.[11]

Botanical description

Appearance

Turmeric is a perennial herbaceous plant, which reaches a stature of up to 1 meter. There are highly branched, yellow to orange, cylindrical, aromatic rhizomes . The leaves are alternate and arranged in two rows . They are divided into leaf sheath, petiole and leaf blade.[12] From the leaf sheaths, a false stem is formed. The petiole is 50 to 115 cm long. The simple leaf blades are usually of a length of 76 to 115 cm and rarely up to 230 cm. They have a width of 38 to 45 cm and are oblong to elliptic narrowing at the tip .

Inflorescence, flower and fruit

In China, the flowering time is usually in August. Terminally on the false stem there is a 12 to 20 cm long inflorescence stem containing many flowers. The bracts are light green and ovate with a length of 3 to 5 centimeters to oblong with a blunt upper end.

At the top of the inflorescence stem bracts are present on which there are no flowers, these are, white to green and sometimes tinged reddish-purple and its upper end is tapered.[13]

The hermaphrodite flowers are zygomorphic and threefold. The three 0.8 to 1.2 centimeters long, sepals are fused, white, have fluffy hairs and the three calyx teeth are unequal. The three bright yellow petals are fused into a corolla tube up to 3 centimeters long. The three corolla lobes have a length of 1 to 1.5 cm, triangular with soft-spiny upper end. While the average corolla lobe is larger than the two lateral. Only the median stamen of the inner circle is fertile. The dust bag is spurred at its base. All other stamens are converted to staminodes. The outer staminodes are shorter than the labellum. The labellum is yellowish, with a yellow ribbon in its center and it is obovate, with a length from 1.2 to 2 cm. Three carpels are under a constant, trilobed ovary adherent, which is sparsely hairy.

The fruit capsule opens with three compartments.

Biochemical composition
Curcumin keto form
Curcumin enol form

The most important chemical components of turmeric are a group of compounds called curcuminoids, which include curcumin (diferuloylmethane), demethoxycurcumin, and bisdemethoxycurcumin. The best studied compound is curcumin, which constitutes 3.14% (on average) of powdered turmeric.[14] In addition there are other important volatile oils such as turmerone, atlantone, and zingiberene. Some general constituents are sugars, proteins, and resins.[5]

Uses

Culinary

Turmeric powder is used extensively in South Asian cuisine.

Turmeric grows wild in the forests of South and Southeast Asia. It is one of the key ingredients in many Asian dishes. Tamil traditional medicine, called Siddha, has recommended turmeric in food for its potential medicinal value, which is a topic of active research. Its use as a coloring agent is not of primary value in South Asian cuisine.

Turmeric is mostly used in savory dishes, but is used in some sweet dishes, such as the cake Sfouf. In India, turmeric plant leaf is used to prepare special sweet dishes, patoleo, by layering rice flour and coconut-jaggery mixture on the leaf, and then closing and steaming it in a special copper steamer (goa).

In recipes outside South Asia, turmeric is sometimes used as an agent to impart a rich, custard-like yellow color. It is used in canned beverages and baked products, dairy products, ice cream, yogurt, yellow cakes, orange juice, biscuits, popcorn color, sweets, cake icings, cereals, sauces, gelatins, etc. It is a significant ingredient in most commercial curry powders.

Most turmeric that is used is in the form of rhizome powder, in some regions (especially in Maharashtra, Goa, Konkan and Kanara), turmeric leaves are used to wrap and cook food. This use of turmeric leaves usually takes place in areas where turmeric is grown locally, since the leaves used are freshly picked. Turmeric leaves impart a distinctive flavor.

Although typically used in its dried, powdered form, turmeric is also used fresh, like ginger. It has numerous uses in Far Eastern recipes, such as pickle made from fresh turmeric that contains large chunks of soft turmeric.

Turmeric is widely used as a spice in South Asian and Middle Eastern cooking. Many Persian dishes use turmeric as a starter ingredient. Almost all Iranian fried dishes consist of oil, onions, and turmeric followed by any other ingredients that are to be included.

In Nepal, turmeric is widely grown and extensively used in many vegetable and meat dishes for its color as well as for its potential value in traditional medicine. In South Africa, turmeric is used to give boiled white rice a golden color.

In Vietnam, turmeric powder is used to color, and enhance the flavors of, certain dishes, such as bánh xèo, bánh kh?t and mi quang. The powder is also used in many other Vietnamese stir fried and soup dishes.

In Indonesia, the turmeric leaves are used for Minangese or Padangese curry base of Sumatra, such as rendang, sate padang and many other varieties.

In medieval Europe, turmeric became known as Indian saffron because it was widely used as an alternative to the far more expensive saffron spice.[15]

Folk medicine and traditional uses

In Tamilnadu, turmeric has been used traditionally for thousands of years as a remedy for stomach and liver ailments, as well as topically to heal sores, basically for its supposed antimicrobial property.[16] In the Siddha system (since c. 1900 BCE) turmeric was a medicine for a range of diseases and conditions, including those of the skin, pulmonary, and gastrointestinal systems, aches, pains, wounds, sprains, and liver disorders. A fresh juice is commonly used in many skin conditions, including eczema, chicken pox, shingles, allergy, and scabies.[17]

Manjal Pal (turmeric milk) is warm milk mixed with some turmeric powder. It is commonly used in Tamilnadu as a home remedy when someone is suffering from fever. Turmeric paste is often used in Tamilnadu as an antiseptic in open wounds, while chun-holud (turmeric with slaked lime) is used to stop bleeding as home remedies. It is also used as a detanning agent in Tamilnadu.[18]

The active compound curcumin is believed to have a wide range of biological effects including anti-inflammatory, antioxidant, antitumour, antibacterial, and antiviral activities, which indicate potential in clinical medicine.[19] In Chinese medicine, it is used for treatment of various infections and as an antiseptic.[20]

Preliminary medical research

Turmeric rhizome.

See also: Curcumin

According to the National Center for Complementary and Alternative Medicine, "there is little reliable evidence to support the use of turmeric for any health condition because few clinical trials have been conducted."[11]

Although trials are ongoing for the use of turmeric to treat cancer, doses needed for any effect are difficult to establish in humans. It is not known what, if any, positive effect turmeric has against cancer or any disease.[21] As of December 2013, turmeric is being evaluated for its potential efficacy against several human diseases in clinical trials, including kidney and cardiovascular diseases, arthritis, several types of cancer and irritable bowel disease.[22]

Specifically, turmeric is also being investigated in relation to Alzheimer's disease,[23] diabetes,[24] and other clinical disorders.[25][26]

However, according to various basic research studies,[27][28][29][30] administration of curcumin or turmeric can suppress several stages of cancer development in multiple tumor models.[28] One study of curcumin on human cancer cells in vitro used hybrid molecules with the anti-nausea drug thalidomide to induce apoptosis in myeloma cancer cells.[31] Some research shows compounds in turmeric to have anti-fungal and antibacterial properties; however, curcumin is not one of them.[32]

Curcumin, the active component of turmeric, has also been shown to be a vitamin D receptor ligand "with implications for colon cancer chemoprevention."[33]

Dye

Turmeric makes a poor fabric dye, as it is not very light fast. However, turmeric is commonly used in Indian and Bangladeshi clothing, such as saris and Buddhist monks' robes.[34] Turmeric (coded as E100 when used as a food additive)[35] is used to protect food products from sunlight. The oleoresin is used for oil-containing products. A curcumin and polysorbate solution or curcumin powder dissolved in alcohol is used for water-containing products. Over-coloring, such as in pickles, relishes, and mustard, is sometimes used to compensate for fading.

In combination with annatto (E160b), turmeric has been used to color cheeses, yogurt, dry mixes, salad dressings, winter butter and margarine. Turmeric is also used to give a yellow color to some prepared mustards, canned chicken broths and other foods (often as a much cheaper replacement for saffron).

Ceremonial uses

Turmeric is considered highly auspicious and holy in Tamil nadu and has been used extensively in various Tamil ceremonies for millennia. Even today it is used in every part of Tamilnadu during wedding ceremonies and religious ceremonies.

Turmeric has played an important role in both Hindu and Tamil spiritualism. The robes of the Tamil monks were traditionally colored with a yellow dye made of turmeric. Because of its yellow-orange coloring, turmeric was associated with the sun or the Thirumal in the mythology of ancient Tamil religion. Yellow is the color of the solar plexus chakra, which in traditional Tamil Siddha medicine is the energy center relating to the metabolic and digestive systems. Orange is the color of the sacral chakra, and tied to the reproductive system.

The plant is used in poosai to represent a form of Kottravai who is said to reside on this plant as herself. The plant is used as a component of navapatrika along with plantain (Banana), Kachvi or Kacci or kochu or Taro, jayanti/ Barley, wood apple (Bilva), pomegranate (darimba), Asoka, manaka or Manakochu and rice paddy or Dhanya.

It is used in poosai to make a form of Ganesha. Yaanaimugathaan, the remover of obstacles, is invoked at the beginning of almost any ceremony and a form of Yaanaimugathaan for this purpose is made by mixing turmeric with water and forming it into a cone-like shape.

Gaye holud (literally "yellow on the body") is a ceremony observed mostly in the region of Bengal (comprising Bangladesh and Indian West Bengal). The gaye holud takes place one or two days before the religious and legal Bengali wedding ceremonies. The turmeric paste is applied by friends to the bodies of the couple. This is said to soften the skin, but also colors them with the distinctive yellow hue that gives its name to this ceremony. It may be a joint event for the bride and groom's families, or it may consist of separate events for the bride's family and the groom's family.

During the Tamil festival Pongal, a whole turmeric plant with fresh rhizomes is offered as a thanksgiving offering to Suryan, the Sun god. Also, the fresh plant sometimes is tied around the sacred Pongal pot in which an offering of pongal is prepared.

In Tamil nadu, as a part of the Tamil marriage ritual, dried turmeric tuber tied with string is used temporarily or permanently as opposed to the Mangalasutra of Hindus in India . The Tamil Marriage act recognizes this custom. Thali necklace is the equivalent of marriage rings in western cultures. In western and coastal India, during weddings of the Marathi and Konkani people, Kannada Brahmins turmeric tubers are tied with strings by the couple to their wrists during a ceremony called Kankanabandhana.[36]

Modern Neopagans list it with the quality of fire, and it is used for power and purification rites.[citation needed]

Friedrich Ratzel in The History of Mankind reported in 1896 that in Micronesia the preparation of turmeric powder for embellishment of body, clothing and utensils had a highly ceremonial character.[37] He quotes an example of the roots being ground by four to six women in special public buildings and then allowed to stand in water. The following morning, three young coconuts and three old soma nuts are offered by a priestess with prayer, after which the dye which has settled down in the water is collected, baked into cakes in coconut molds, wrapped in banana leaves, and hung up in the huts till required for use.

References

"Curcuma longa information from NPGS/GRIN". ars-grin.gov.
Chan, E.W.C. et al.; Lim, Y.Y.; Wong, S.K.; Lim, K.K.; Tan, S.P.; Lianto, F.S.; Yong, M.Y. (2009). "Effects of different drying methods on the antioxidant properties of leaves and tea of ginger species". Food Chemistry 113 (1): 166–172. doi:10.1016/j.foodchem.2008.07.090.
Materia Indica, 1826, Whitelaw Ainslie, M.D. M.R.A.S., via Google Books
Indian Spices. "Turmeric processing". kaubic.in.
a b Nagpal M, Sood S (2013). "Role of curcumin in systemic and oral health: An overview". J Nat Sci Biol Med 4 (1): 3–7. doi:10.4103/0976-9668.107253. PMC 3633300. PMID 23633828.
Tahira JJ et al (2010). "Weed flora of Curcuma longa". Pakistan J Weed Sci Res 16 (2): 241–6.
Dictionary.com Unabridged Based on the Random House Dictionary, © Random House, Inc. 2013. "Turmeric". Dictionary.com. 2012.
"Trade Related Intellectual Property Rights (TRIPs) and Farmers' Rights".
Royal Botanical Gardens, UK. "Turmeric – History". Plant Cultures. Royal Botanical Gardens.
Chattopadhyay, Ishita; Kaushik Biswas, Uday Bandyopadhyay, and Ranajit K. Banerjee (10 July 2004). "Turmeric and curcumin: Biological actions and medicinal applications". Current Science (Indian Academy of Sciences) 87 (1): 44–53. ISSN 0011-3891.
a b "Herbs at a Glance: Turmeric, Science & Safety". National Center for Complementary and Alternative Medicine (NCCAM), National Institutes of Health. 2012.  
Curcuma longa A Modern Herbal, M Grieve.
Curcuma longa Linn. Description from Flora of China , South China Botanical Garden.
Tayyem RF, Heath DD, Al-Delaimy WK, Rock CL (2006). "Curcumin content of turmeric and curry powders". Nutr Cancer 55 (2): 126–131. doi:10.1207/s15327914nc5502_2. PMID 17044766.
Is it Turmeric or Saffron?
Chaturvedi TP (2009). "Uses of turmeric in dentistry: an update". Indian J Dent Res 20 (1): 107–109. PMID 19336870.
Khalsa SVK. "Turmeric, The Golden Healer". healthy.net.
Prerna Singh (pp-19,2012). The Everything Indian Slow Cooker Cookbook. Google books.
Aggarwal BB, Sundaram C, Malani N, Ichikawa H (2007). "Curcumin: the Indian solid gold". Adv Exp Med Biol 595 (1): 1–75. doi:10.1007/978-0-387-46401-5_1. PMID 17569205.
Evans A (27 January 2012). "The amazing health benefits of turmeric". mother nature network. MNN Holdings, LLC.
"Turmeric". American Cancer Society. 7 December 2012.
"Clinical trials on turmeric". National Institutes of Health, Clinical Trials Registry. December 2013.
Mishra S, Palanivelu K (Jan–March, 2008). "The effect of curcumin (turmeric) on Alzheimer's disease: An overview". Ann Indian Acad Neurol 11 (1): 13–9. doi:10.4103/0972-2327.40220. PMC 2781139. PMID 19966973.
Boaz M, Leibovitz E, Bar Dayan Y, Wainstein J (2011). "Functional foods in the treatment of type 2 diabetes: olive leaf extract, turmeric and fenugreek, a qualitative review". Func Foods Health Dis 1 (11): 472–81.
Henrotin Y, Clutterbuck AL, Allaway D, et al. (February 2010). "Biological actions of curcumin on articular chondrocytes". Osteoarthr. Cartil. 18 (2): 141–9. doi:10.1016/j.joca.2009.10.002. PMID 19836480.
Gregory PJ, Sperry M, Wilson AF (January 2008). "Dietary supplements for osteoarthritis". Am Fam Physician 77 (2): 177–84. PMID 18246887.
"Health effects of Turmeric". Health effects of Herbs. University of Maryland Medical Center.
a b Singletary, K (2010). Potential Health Benefits of Turmeric. MSI.
Maitra, Anirban; Saraswati kumar (16 July 2013). "A Simple Spice That May Battle Cancer". John Hopkins Medicine. Summer 2013 (21).
Hylind, Linda. "Johns Hopkins Gazette reports on their study on turmeric". Chemicals in Curry and Onions May Help Stop Colon Cancer. American Cancer Society and National Institutes of Health.
Liu, Kai; Zhang, Datong; Chojnacki, Jeremy; Du, Yuhong; Fu, Haian; Grant, Steven; Zhang, Shijun (2013). "Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma". Organic & Biomolecular Chemistry 11 (29): 4757. doi:10.1039/C3OB40595H. PMID 23784627.
Ragasa C, Laguardia M, Rideout J (2005). "Antimicrobial sesquiterpenoids and diarylheptanoid from Curcuma domestica". ACGC Chem Res Comm 18 (1): 21–24.
http://www.ncbi.nlm.nih.gov/pubmed/20153625
Brennan, James (15 Oct 2008). "Turmeric". Lifestyle. The National.
UK food guide
Singh KS, Bhanu BV (2004). People of India: Maharashtra, Volume 1. Popular Prakashan. pp. 2130 pages(see page:487). ISBN 9788179911006.
Ratzel, Friedrich. The History of Mankind. (London: MacMillan, 1896). URL: www.inquirewithin.biz/history/american_pacific/oceania/oceania-utensils.htm acces



Wikipedia.org

Curcumin

Enol form

Keto form


Skeletal formula
Enol form
Skeletal formula
Keto form
Ball-and-stick model
Ball-and-stick model
IUPAC name[hide]

(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
Other names[hide]

Diferuloylmethane; curcumin I; C.I. 75300; Natural Yellow 3
Identifiers
CAS number     458-37-7 Yes
PubChem     969516
ChemSpider     839564 Yes
UNII     IT942ZTH98 Yes
ChEBI     CHEBI:3962 Yes
ChEMBL     CHEMBL116438
Molecular formula     C21H20O6
Molar mass     368.38 g mol-1
Appearance     Bright yellow-orange powder
Melting point     183 °C; 361 °F; 456 K

Curcumin (pronounced "Kur kyoo min")[1] is a diarylheptanoid. It is the principal curcuminoid of the popular South Asian spice turmeric, which is a member of the ginger family (Zingiberaceae). Turmeric's other two curcuminoids are desmethoxycurcumin and bis-desmethoxycurcumin. The curcuminoids are natural phenols that are responsible for the yellow color of turmeric. Curcumin can exist in several tautomeric forms, including a 1,3-diketo form and two equivalent enol forms. The enol form is more energetically stable in the solid phase and in solution.[2]

Curcumin can be used for boron quantification in the curcumin method. It reacts with boric acid to form a red-colored compound, rosocyanine.

Curcumin is brightly yellow colored and may be used as a food coloring. As a food additive, its E number is E100.[3]

Chemistry

Curcumin incorporates several functional groups. The aromatic ring systems, which are phenols, are connected by two a,ß-unsaturated carbonyl groups. The diketones form stable enols and are readily deprotonated to form enolates; the a,ß-unsaturated carbonyl group is a good Michael acceptor and undergoes nucleophilic addition. The structure was first identified in 1910 by J. Milobedzka, Stanislaw Kostanecki and Wiktor Lampe.[4]

Curcumin is used as an indicator for boron.[5]

Biosynthesis

The biosynthetic route of curcumin has proven to be very difficult for researchers to determine. In 1973 Roughly and Whiting proposed two mechanisms for curcumin biosynthesis. The first mechanism involved a chain extension reaction by cinnamic acid and 5 malonyl-CoA molecules that eventually arylized into a curcuminoid. The second mechanism involved two cinnamate units being coupled together by malonyl-CoA. Both mechanisms use cinnamic acid as their starting point, which is derived from the amino acid phenylalanine. This is noteworthy because plant biosyntheses employing cinnamic acid as a starting point are rare compared to the more common use of p-coumaric acid.[6] Only a few identified compounds, such as anigorufone and pinosylvin, use cinnamic acid as their start molecule.[7][8] An experimentally backed route was not presented until 2008. This proposed biosynthetic route follows both the first and second mechanisms suggested by Roughley and Whiting. However, the labeling data supported the first mechanism model in which 5 malonyl-CoA molecules react with cinnamic acid to form curcumin. However, the sequencing in which the functional groups, the alcohol and the methoxy, introduce themselves onto the curcuminoid seems to support more strongly the second proposed mechanism.[6] Therefore, it was concluded the second pathway proposed by Roughly and Whiting was correct.

Biosynthetic pathway of curcumin in Curcuma longa.[6]

Preliminary research for potential health effects

Research has identified curcumin as the agent responsible for most of the biological activity of turmeric.[9]

Laboratory research shows that curcumin is a pleiotropic molecule possibly capable of interacting with molecular targets involved in inflammation.[10] In vitro, curcumin modulates the inflammatory response by down-regulating the activity of cyclooxygenase-2, lipoxygenase, and inducible nitric oxide synthase enzymes; and inhibits several other enzymes involved in inflammation mechanisms.[11][12]

A systematic review of the use of curcumin based supplements for treating diabetic wounds found no significant positive outcome for human use.[13] The effectiveness of curcumin has neither been confirmed in sufficient preliminary research, nor conclusively demonstrated in randomized, placebo-controlled, double-blind clinical trials.[14]

A survey of the literature shows a number of other potential uses and that daily doses over a 3-month period of up to 12 grams proved safe.[15]

Clinical trials in humans are studying the effect of curcumin on various diseases, including multiple myeloma, pancreatic cancer, myelodysplastic syndromes, colon cancer, psoriasis, arthritis and Alzheimer's disease.[16][17][18][19] A number of trials studying curcumin efficacy and safety revealed poor absorption and low bioavailability. Methods to possibly increase absorption and systemic bioavailability are under study, including combined administration with piperine and quercetin.[20]

Curcumin has also been shown to be a vitamin D receptor ligand "with implications for colon cancer chemoprevention." [21]

Bioavailability

In Phase I clinical trials, dietary curcumin was shown to exhibit poor bioavailability (i.e., low levels in plasma and tissues).[22] Potential factors that limit the bioavailability of curcumin include poor absorption, rapid metabolism, and rapid systemic elimination. Numerous approaches to increasing curcumin bioavailability have been explored, including the use of adjuvants like piperine.[22]

The bioavailability of curcumin ingested in foods may be increased as a result of cooking or dissolution in oil.[23]

Resistance

Overexpression of the ATP-binding cassette gene ABCA1 has been reported to confer resistance to curcumin in terms of NFkappaB activation that can be reversed by ABCA1 silencing.[24]

Potential risks and side effects

Kawanishi et al. remarked that curcumin, like many antioxidants, can be a "double-edged sword" where, in the test tube, carcinogenic and pro-oxidant effects may be seen in addition to anticancer and antioxidant effects.[25] Carcinogenic effects are inferred from interference with the p53 tumor suppressor pathway, an important factor in human colon cancer.[26] In vitro and in vivo studies suggest that curcumin can have carcinogenic effects.[27][28][29]

Clinical studies in humans with high doses (2–12 grams) of curcumin have shown few side effects, with some subjects reporting mild nausea or diarrhea.[30] More recently, curcumin was found to alter iron metabolism by chelating iron and suppressing the protein hepcidin, potentially causing iron deficiency in susceptible patients.[31] Further studies seem to be necessary to establish the benefit/risk profile of curcumin.[27]

There is no or little evidence to suggest curcumin is either safe or unsafe for pregnant women. However, there is still some concern medicinal use of products containing curcumin could stimulate the uterus, which may lead to a miscarriage, although there is not much evidence to support this claim. According to experiments done on rats and guinea pigs, there is no obvious effect (neither positive, nor negative) on the pregnancy rate or number of live or dead embryos.[32] Curcumin has embryotoxic and teratogenic effects on zebrafishes (Danio rerio) embryos.[33]

References

Notes

Dorland (2011-06-09). Dorland's Illustrated Medical Dictionary, 32nd Edition. ISBN 1455709859. Retrieved May 19, 2013. Published 2011.
Kolev, Tsonko M.; Velcheva, Evelina A.; Stamboliyska, Bistra A.; Spiteller, Michael (2005). "DFT and experimental studies of the structure and vibrational spectra of curcumin". International Journal of Quantum Chemistry 102 (6): 1069–79. doi:10.1002/qua.20469.
Food Standards Australia New Zealand. "Food Additives- Numerical List". Retrieved 2009-12-02.
Milob?dzka, J.; v. Kostanecki, St.; Lampe, V. (1910). "Zur Kenntnis des Curcumins". Berichte der deutschen chemischen Gesellschaft 43 (2): 2163–70. doi:10.1002/cber.191004302168.
"EPA Method 212.3: Boron (Colorimetric, Curcumin)".
a b c Kita, Tomoko; Imai, Shinsuke; Sawada, Hiroshi; Kumagai, Hidehiko; Seto, Haruo (2008). "The Biosynthetic Pathway of Curcuminoid in Turmeric (Curcuma longa) as Revealed by 13C-Labeled Precursors". Bioscience, Biotechnology, and Biochemistry 72 (7): 1789. doi:10.1271/bbb.80075.
Schmitt, Bettina; Hölscher, Dirk; Schneider, Bernd (2000). "Variability of phenylpropanoid precursors in the biosynthesis of phenylphenalenones in Anigozanthos preissii". Phytochemistry 53 (3): 331–7. doi:10.1016/S0031-9422(99)00544-0. PMID 10703053.
Gehlert, R.; Schoeppner, A.; Kindl, H. (1990). "Stilbene Synthase from Seedlings of Pinus sylvestris: Purification and Induction in Response to Fungal Infection" (pdf). Molecular Plant-Microbe Interactions 3 (6): 444–449. doi:10.1094/MPMI-3-444.
Aggarwal, Bharat B.; Sundaram, Chitra; Malani, Nikita; Ichikawa, Haruyo (2007). "Curcumin: the Indian solid gold". Advances in Experimental Medicine and Biology. Advan Exp Med Biol 595: 1–75. doi:10.1007/978-0-387-46401-5_1. ISBN 978-0-387-46400-8. PMID 17569205.
Gupta SC et al. (2011). "Multitargeting by curcumin as revealed by molecular interaction studies". Nat Prod Rep 28 (12): 1937–55. doi:10.1039/c1np00051a. PMC 3604998. PMID 21979811.
Abe Y, Hashimoto S, Horie T (1999). "Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages". Pharmacol Res 39 (1): 41–7. doi:10.1006/phrs.1998.0404. PMID 10051376.
Goel A, Kunnumakkara AB, Aggarwal BB (2008). "Curcumin as "Curecumin": from kitchen to clinic". Biochem Pharmacol 75 (4): 787–809. doi:10.1016/j.bcp.2007.08.016. PMID 17900536.
Maier, HM; Ilich, JZ; Kim, JS; Spicer, MT (2013). "Nutrition supplementation for diabetic wound healing: A systematic review of current literature". Skinmed 11 (4): 217–24; quiz 224–5. PMID 24053007.
Mancuso, C.; Barone, E. (2009). "Curcumin in clinical practice: myth or reality?". Trends in Pharmacological Science 30 (7): 333–334. doi:10.1016/j.tips.2009.04.004. PMID 19523696.
Goel, Ajay; Kunnumakkara, Ajaikumar B.; Aggarwal, Bharat B. (2008). "Curcumin as "Curecumin": From kitchen to clinic". Biochemical Pharmacology 75 (4): 787–809. doi:10.1016/j.bcp.2007.08.016. PMID 17900536. "Pilot phase I clinical trials have shown curcumin to be safe even when consumed at a daily dose of 12g for 3 months."
Hatcher, H.; Planalp, R.; Cho, J.; Torti, F. M.; Torti, S. V. (2008). "Curcumin: From ancient medicine to current clinical trials". Cellular and Molecular Life Sciences 65 (11): 1631–52. doi:10.1007/s00018-008-7452-4. PMID 18324353.
Yan, Jiao; Wilkinson, Di, Wang, Hatcher, Kock, D'Agostino, Jr, Knovich, Torti, Torti corresponding author (8 January 2009). "Red Cells, Iron, and Erythropoiesis Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator". Blood. 113(2): (Prepublished online 2008 September 24.): 462–469. doi:10.1182/blood-2008-05-155952. PMC 2615657. PMID 18815282.
"ClinicalTrials.gov: Current clinical trials on curcumin". US National Institutes of Health, Clinical Trial Registry. 2013.
Zhao, LN.; Chiu, SW.; Benoit, J.; Chew, LY.; Mu, Y. (Jun 2012). "The effect of curcumin on the stability of Aß dimers". J Phys Chem B 116 (25): 7428–35. doi:10.1021/jp3034209. PMID 22690789.
Shehzad A et al. (2010). "Curcumin therapeutic promises and bioavailability in colorectal cancer". Drugs of Today 46 (7): 523–32. doi:10.1358/dot.2010.46.7.1509560. PMID 20683505.
Bartik, L; Whitfield, GK; Kaczmarska, M; Lowmiller, CL; Moffet, EW; Furmick, JK; Hernandez, Z; Haussler, CA; Haussler, MR; Jurutka, PW (2010). "Curcumin: A novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention". The Journal of nutritional biochemistry 21 (12): 1153–61. doi:10.1016/j.jnutbio.2009.09.012. PMC 2891903. PMID 20153625.
a b Anand, P.; Kunnumakkara, A. B.; Newman, R. A.; Aggarwal, B. B. (2007). "Bioavailability of curcumin: problems and promises". Molecular Pharmaceutics 4 (6): 807–818. doi:10.1021/mp700113r. PMID 17999464.
Marczylo, T. H.; Verschoyle, R. D.; Cooke, D. N.; Morazzoni, P.; Steward, W. P.; Gescher, A. J. (2007). "Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine". Cancer Chemotherapy and Pharmacology 60 (2): 171–177. doi:10.1007/s00280-006-0355-x. PMID 17051370.
Bachmeier BE, Iancu CM, Killian PH, Kronski E, Mirisola V, Angelini G, et al. (2009). "Overexpression of the ATP binding cassette gene ABCA1 determines resistance to Curcumin in M14 melanoma cells". Mol Cancer 8: 129–141. doi:10.1186/1476-4598-8-129. PMC 2804606. PMID 20030852.
Kawanishi, S.; Oikawa, S.; Murata, M. (2005). "Evaluation for safety of antioxidant chemopreventive agents". Antioxidants & Redox Signaling 7 (11–12): 1728–1739. doi:10.1089/ars.2005.7.1728. PMID 16356133.
Moos, P. J.; Edes, K.; Mullally, J. E.; Fitzpatrick, F. A. (2004). "Curcumin impairs tumor suppressor p53 function in colon cancer cells". Carcinogenesis 25 (9): 1611–1617. doi:10.1093/carcin/bgh163. PMID 15090465.
a b Burgos-Moron, E.; Calderón-Montaño, J. M.; Salvador, J.; Robles, A.; López-Lázaro, M. (2010). "The dark side of curcumin" (pdf). International Journal of Cancer 126 (7): 1771–1775. doi:10.1002/ijc.24967. PMID 19830693.
Dance-Barnes, S. T.; Kock, N. D.; Moore, J. E.; Lin, E. Y.; Mosley, L. J., et al. (2009). "Lung tumor promotion by curcumin". Carcinogenesis 30 (6): 1016–1023. doi:10.1093/carcin/bgp082. PMC 2691137. PMID 19359593.
López-Lázaro, M.; Kock, N. D.; Moore, J. E.; Lin, E. Y.; Mosley, L. J., et al. (2008). "Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent". Molecular Nutrition and Food Research 52 (Supplement 1): S103–S127. doi:10.1002/mnfr.200700238. PMID 18496811.
Hsu, C. H.; Cheng, A. L. (2007). "Clinical studies with curcumin". Advances in Experimental Medicine and Biology. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 595: 471–480. doi:10.1007/978-0-387-46401-5_21. ISBN 978-0-387-46400-8. PMID 17569225.
Jiao, Y.; Wilkinson, J.; Di, X.; Wang, W.; Hatcher, H., et al. (January 2009). "Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator". Blood 113 (2): 462–469. doi:10.1182/blood-2008-05-155952. PMC 2615657. PMID 18815282.
Vijayalaxmi (1980). "Genetic effects of turmeric and curcumin in mice and rats". Mutation Research 79 (2): 125–132. doi:10.1016/0165-1218(80)90080-4. PMID 7432370.
Wu, J. Y.; Lin, C. Y.; Lin, T. W.; Ken, C. F.; Wen, Y. D. (2007). "Curcumin Affects Development of Zebrafish Embryo". Biol. Pharm. Bull 30 (7): 1336–1339. doi:10.1248/bpb.30.1336. PMID 17603177.

See also: Esatbeyoglu, Tuba; Huebbe, Patricia; Ernst, Insa M. A.; Chin, Dawn, et al.; Wagner, Anika E.; Rimbach, Gerald (2012). "Curcumin-From Molecule to Biological Function". Angewandte Chemie International Edition 51 (22): 5308. doi:10.1002/anie.201107724.
External links



http://umm.edu/health/medical/altmed/herb/turmeric
University of Maryland Medical Center

Turmeric

Overview

Turmeric (Curcuma longa) has been used for 4,000 years to treat a variety of conditions. Studies show that turmeric may help fight infections and some cancers, reduce inflammation, and treat digestive problems, and it has gotten a lot of press lately.

But remember several facts when you hear news reports about turmeric. First, many studies have taken place in test tubes and animals, and turmeric may not work as well in humans. Second, some studies have used an injectable form of curcumin, the active substance in turmeric. Finally, some of the studies show conflicting evidence.

Turmeric is widely used in cooking and gives Indian curry its flavor and yellow color. It is also used in mustard and to color butter and cheese. Turmeric has been used in both Ayurvedic and Chinese medicine as an anti-inflammatory, to treat digestive and liver problems, skin diseases, and wounds.

Curcumin is also a powerful antioxidant. Antioxidants scavenge molecules in the body known as free radicals, which damage cell membranes, tamper with DNA, and even cause cell death. Antioxidants can fight free radicals and may reduce or even help prevent some of the damage they cause.

In addition, curcumin lowers the levels of two enzymes in the body that cause inflammation. It also stops platelets from clumping together to form blood clots.

Research suggests that turmeric may be helpful for the following conditions:

Indigestion or Dyspepsia

Curcumin stimulates the gallbladder to produce bile, which some people think may help improve digestion. The German Commission E, which determines which herbs can be safely prescribed in Germany, has approved turmeric for digestive problems. And one double-blind, placebo-controlled study found that turmeric reduced symptoms of bloating and gas in people suffering from indigestion.

Ulcerative colitis

Turmeric may help people with ulcerative colitis stay in remission. Ulcerative colitis is a chronic disease of the digestive tract where symptoms tend to come and go. In one double-blind, placebo-controlled study, people whose ulcerative colitis was in remission took either curcumin or placebo, along with conventional medical treatment, for 6 months. Those who took curcumin had a relapse rate much lower than those who took placebo.

Stomach Ulcers

Turmeric does not seem to help treat stomach ulcers. In fact, there is some evidence that it may increase stomach acid, making existing ulcers worse. (See "Precautions" section.)

Osteoarthritis

Because of its ability to reduce inflammation, researchers have wondered if turmeric may help relieve osteoarthritis pain. One study found that people using an Ayurvedic formula of herbs and minerals with turmeric, winter cherry (Withinia somnifera), boswellia (Boswellia serrata), and zinc had less pain and disability. But it’s impossible to know whether it was turmeric or one of the other supplements -- or all of them together -- that was responsible.

Heart Disease

Early studies suggested that turmeric may help prevent atherosclerosis, the buildup of plaque that can block arteries and lead to heart attack or stroke. In animal studies, an extract of turmeric lowered cholesterol levels and kept LDL "bad" cholesterol from building up in blood vessels. Because it stops platelets from clumping together, turmeric may also prevent blood clots from building up along the walls of arteries. But a double-blind, placebo-controlled study found that taking curcumin, the active ingredient in turrmeric, at a dose of up to 4 g per day did not improve cholesterol levels.

Cancer

There has been a great deal of research on turmeric's anti-cancer properties, but results are still very early. Evidence from test tube and animal studies suggests that curcumin may help prevent or treat several types of cancers, including prostate, breast, skin, and colon cancer. Its preventive effects may be because it is a strong antioxidant, protecting cells from damage. More research is needed. Cancer should be treated with conventional medications. Don’t use alternative therapies alone to treat cancer. If you choose to use complementary therapies along with your cancer treatment, make sure you tell all your doctors.

Bacterial and Viral Infections

Test tube and animal studies suggest turmeric may kill bacteria and viruses. But researchers don’t know whether it would work in people.

Uveitis

A preliminary study suggests curcumin may help treat uveitis, an inflammation of the eye’s iris. In one study of 32 people with chronic anterior uveitis, curcumin was effective as corticosteroids, the type of medication usually prescribed. More research is needed.

Plant Description

A relative of ginger, turmeric is a perennial plant that grows 5 - 6 feet high in the tropical regions of Southern Asia, with trumpet-shaped, dull yellow flowers. Its roots are bulbs that also produce rhizomes, which then produce stems and roots for new plants. Turmeric is fragrant and has a bitter, somewhat sharp taste. Although it grows in many tropical locations, the majority of turmeric is grown in India, where it is used as a main ingredient in curry.

Parts Used

The roots, or rhizomes and bulbs, are used in medicine and food. They are generally boiled and then dried, turning into the familiar yellow powder. Curcumin, the active ingredient, has antioxidant properties. Other substances in this herb have antioxidant properties as well.

Available Forms

Turmeric is available in the following forms:

    Capsules containing powder
    Fluid extract
    Tincture

Because bromelain increases the absorption and anti-inflammatory effects of curcumin, it is often combined with turmeric products.

How to Take It

Pediatric

Turmeric supplements haven’t been studied in children, so there is no recommended dose.

Adult

The following are doses recommended for adults:

    Cut root: 1.5 - 3 g per day
    Dried, powdered root: 1 - 3 g per day
    Standardized powder (curcumin): 400 - 600 mg, 3 times per day
    Fluid extract (1:1) 30 - 90 drops a day
    Tincture (1:2): 15 - 30 drops, 4 times per day

Precautions

The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and may interact with other herbs, supplements, or medications. For these reasons, you should take herbs with care, under the supervision of a health care provider.

Turmeric in food is considered safe.

Turmeric and curcumin supplements are considered safe when taken at the recommended doses. However, taking large amounts of turmeric for long periods of time may cause stomach upset and, in extreme cases, ulcers. People who have gallstones or obstruction of the bile passages should talk to their doctor before taking turmeric.

If you have diabetes, talk to your doctor before taking turmeric supplements. Turmeric may lower blood sugar levels, and when combined with medications for diabetes could cause hypoglycemia (low blood sugar).

Although it is safe to eat foods with turmeric, pregnant and breastfeeding women should not take turmeric supplements.

Because turmeric may act like a blood-thinner, you should stop taking it at least 2 weeks before surgery. Tell your doctor and surgeon that you have been taking turmeric.

Possible Interactions

If you are being treated with any of the following medications, you should not use turmeric or curcumin in medicinal forms without first talking to your health care provider.

Blood-thinning Medications -- Turmeric may make the effects of these drugs stronger, raising the risk of bleeding. Blood-thinners include warfarin (Coumadin), clopidogrel (Plavix), and aspirin, among others.

Drugs that reduce stomach acid -- Turmeric may interfere with the action of these drugs, increasing the production of stomach acid:

    Cimetidine (Tagamet)
    Famotidine (Pepcid)
    Ranitidine (Zantac)
    Esomeprazole (Nexium)
    Omeprazole
    Lansoprazole (Prevacid)

Diabetes Medications -- Turmeric may make the effects of these drugs stronger, increasing the risk of hypoglycemia (low blood sugar).

Supporting Research

Aggarwal BB, Sundaram C, Malani N, Ichikawa H. Curcumin: the Indian solid gold. Adv Exp Med Biol. 2007;595:1-75.

Asai A, Miyazawa T. Dietary curcuminoids prevent high-fat diet-induced lipid accumulation in rat liver and epididymal adipose tissue. J Nutr. 2001;131(11):2932-2935.

Baum L, et al. Curcumin effects on blood lipid profile in a 6-month human study. Pharmacol Res. 2007;56(6):509-14.

Blumenthal M, Goldberg A, Brinckmann J. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000:379-384.

Curcuma longa (turmeric). Monograph. Altern Med Rev. 2001;6 Suppl:S62-S66.

Darvesh AS, Aggarwal BB, Bishayee A. Curcumin and Liver Cancer: A Review. Curr Pharm Biotechnol. 2011 Apr 5. [Epub ahead of print]

Davis JM, Murphy EA, Carmichael MD, Zielinski MR, Groschwitz CM, Brown AS, Ghaffar A, Mayer EP. Curcumin effects on inflammation and performance recovery following eccentric exercise-induced muscle damage. Am J Physiol Regul Integr Comp Physiol. 2007 Mar 1 [Epub ahead of print]

Dorai T, Cao YC, Dorai B, Buttyan R, Katz AE. Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate. 2001;47(4):293-303.

Dorai T, Gehani N, Katz A. Therapeutic potential of curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein. Mol Urol. 2000;4(1):1-6.

Funk JL, Frye JB, Oyarzo JN, Kuscuoglu N, Wilson J, McCaffrey G, et al. Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis. Arthritis Rheum. 2006 Nov;54(11):3452-64.

Gautam SC, Gao X, Dulchavsky S. Immunodilation by curcumin. Adv Exp Med Biol. 2007;595:321-41.

Gescher A J, Sharma R A, Steward W P. Cancer chemoprevention by dietary constituents: a tale of failure and promise. Lancet Oncol. 2001;2(6):371-379.

Goel A, Kunnumakkara AB, Aggarwal BB. Curcumin as "Curecumin": from kitchen to clinic. Biochem Pharmacol. 2008;75(4):787-809.

Hanai H, Iida T, Takeuchi K, Watanabe F, Maruyama Y, Andoh A, et al. Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial. Clin Gastroenterol Hepatol. 2006 Dec;4(12):1502-6.

Handler N, Jaeger W, Puschacher H, Leisser K, Erker T. Synthesis of novel curcumin analogues and their evaluation as selective cyclooxygenase-1 (COX-1) inhibitors. Chem Pharm Bull (Tokyo). 2007 Jan;55(1):64-71.

Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. 2000;57(13):1221-1227.

Jagetia GC, Aggarwal BB. "Spicing up" of the immune system by curcumin. J Clin Immunol. 2007;27(1):19-35.

Johnson JJ, Mukhtar H. Curcumin for chemoprevention of colon cancer. Cancer Lett. 2007 Apr 18; [Epub ahead of print]

Kim MS, Kang HJ, Moon A. Inhibition of invasion and induction of apoptosis by curcumin in H-ras-transformed MCF10A human breast epithelial cells. Arch Pharm Res. 2001;24(4):349-354.

Krishnaswamy K. Traditional Indian spices and their health significance. Asia Pac J Clin Nutr. 2008;17 Suppl 1:265-8.

Pari L, Tewas D, Eckel J. Role of curcumin in health and disease. Arch Physiol Biochem. 2008;114(2):127-49.

Phan TT, See P, Lee ST, Chan SY. Protective effects of curcumin against oxidative damage on skin cells in vitro: its implication for wound healing. J Trauma 2001;51(5):927-931.

Rakel D. Rakel: Integrative Medicine, 2nd ed. Philadelphia, PA: Saunders; 2008;80.

Rao CV. Regulation of COX and LOX by curcumin. Adv Exp Med Biol. 2007;595:213-26.

Sharma RA, Ireson CR, Verschoyle RD. Effects of dietary curcumin on glutathione S-Transferase and Malondialdehyde-DNA adducts in rat liver and colon mucosa: relationship with drug levels. Clin Cancer Res. 2001;7:1452-1458.

Sharma RA, Steward WP, Gescher AJ. Pharmacokinetics and pharmacodynamics of curcumin. Adv Exp Med Biol. 2007;595:453-70.

Shehzad A, Khan S, Shehzad O, Lee YS. Curcumin therapeutic promises and bioavailability in colorectal cancer. Drugs Today (Barc). 2010 Jul;46(7):523-32. Review.

Shishodia S, Singh T, Chaturvedi MM. Modulation of transcription factors by curcumin. Adv Exp Med Biol. 2007;595:127-48.

Su CC, Lin JG, Li TM, Chung JG, Yang JS, Ip SW, et al. Curcumin-induced apoptosis of human colon cancer colo 205 cells through the production of ROS, Ca2+ and the activation of caspase-3. Anticancer Res. 2006 Nov-Dec;26(6B):4379-89.

Suryanarayana P, Satyanarayana A, Balakrishna N, Kumar PU, Reddy GB. Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat. Med Sci Monit. 2007;13(12):BR286-92.

White B, Judkins DZ. Clinical Inquiry. Does turmeric relieve inflammatory conditions? J Fam Pract. 2011 Mar;60(3):155-6. Review.

Zafir A, Banu N. Antioxidant potential of fluoxetine in comparison to Curcuma longa in restraint-stressed rats.
Eur J Pharmacol. 2007;572(1):23-31.
 

 
Cancer Lett. 2014 Jan 23

Targeting Cancer Stem Cells by Curcumin and Clinical Applications.

Yanyan Li, Tao Zhang
 
Abstract: Curcumin is a well-known dietary polyphenol derived from the rhizomes of turmeric, an Indian spice. The anticancer effect of curcumin has been demonstrated in many cell and animal studies, and recent research has shown that curcumin can target cancer stem cells (CSCs). CSCs are proposed to be responsible for initiating and maintaining cancer, and contribute to recurrence and drug resistance. A number of studies have suggested that curcumin has the potential to target CSCs through regulation of CSC self-renewal pathways (Wnt/ß-catenin, Notch, Sonic Hedgehog) and specific microRNAs involved in acquisition of epithelial-mesenchymal transition (EMT). The potential impact of curcumin, alone or in combination with other anticancer agents, on CSCs was evaluated as well. Furthermore, the safety and tolerability of curcumin have been well-established by numerous clinical studies. Importantly, the low bioavailability of curcumin has been dramatically improved through the use of structural analogues or special formulations. More clinical trials are underway to investigate the efficacy of this promising agent in cancer chemoprevention and therapy. In this article, we review the effects of curcumin on CSC self-renewal pathways and specific microRNAs, as well as its safety and efficacy in recent human studies. In conclusion, curcumin could be a very promising adjunct to traditional cancer treatments.



http://www.greenmedinfo.com/blog/600-reasons-turmeric-may-be-worlds-most-important-herb
http://www.greenmedinfo.com/substance/turmeric

Turmeric Database

by

Sayer Ji

[ Condensed Version ]

A combination of artichoke leaf, dandelion root, turmeric root and rosemary essential oil has therapeutic actions in relieving symptoms in functional dyspepsia.
Minerva Gastroenterol Dietol. 2010 Jun;56(2):93-9.

A combination of Saw Palmetto, Nettle, Curcumin and Quercetin significantly improves treatment outcome of prulifloxacin in bacterial prostatitis patients.
Int J Antimicrob Agents. 2009 Jun;33(6):549-53

A complex of curcumin and phosphatidylcholine is effective in reducing the symptoms of ostearthritis.
Altern Med Rev. 2010 Dec;15(4):337-44

A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut.
Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):120-5
.
A multi-herbal product called Protandim has significant antioxidant properties in human subjects.
Arzneimittelforschung. 2006;56(6):387-93

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress.
Drugs R D. 2008;9(4):243-50

An exclusion diet and nutraceutical therapy has significant therapeutic effects in juvenile Crohn's disease.
J Am Coll Nutr. 2009 Jun;28(3):277-85

Bioavailability Study: Piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.
Planta Med. 1998 May;64(4):353-6

Bioflavonoid therapy with curcumin and quercetin improves cadaveric renal transplantation in humans.
Transplantation. 2005 Dec 15;80(11):1556-9

Chelidonium and turmeric root extract have a therapeutic effect on upper abdominal pain due to functional disorders of the biliary system.
Med Klin (Munich). 1999 Aug 15;94(8):425-30

Curcuma longa (turmeric) and tinospora cordifolia (guduchi) prevents antibiotic-induced liver damage in patients with tubercolosis.
World J Gastroenterol. 2008 Aug 14;14(30):4753-62

Curcumin acts as an adjuvant to imatinib in decreasing the NO levels and may help in the treatment of CML patients.
J Oncol Pharm Pract. 2011 Aug 15

Curcumin alleviates ethanol-induced oxidative damage in liver cells.
J Ethnopharmacol. 2010 Jan 18

Curcumin and Boswellia serrata are safe and tolerable and helped to improvethe levels of an inflammatory cytokine (IL-6).
J Complement Integr Med. 2013 ;10(1):1-10

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.
Antioxid Redox Signal. 2010 Jan 19

Curcumin appears safe and effective in maintaining remission in patients with quiescent ulcerative colitis.
Clin Gastroenterol Hepatol. 2006 Dec;4(12):1502-6

Curcumin appears to enhance clearance of amyloid-beta in Alzheimer's disease patients.
J Alzheimers Dis. 2006 Sep;10(1):1-7

Curcumin compares favorably with corticosteroid therapy in the management of chronic anterior uveitis.
Phytother Res. 1999 Jun;13(4):318-22

Curcumin exhibits anti-pre-cancer activity by increasing levels of vitamins C and E, and preventing lipid peroxidation and DNA damage.
J Oral Sci. 2010;52(2):251-6

Curcumin has a contractive effect on human gallbladder function.
J Bras Pneumol. 2006 Jan-Feb;32(1):66-74

Curcumin has anti-inflammatory properties in patients with postoperative inflammation.
Int J Clin Pharmacol Ther Toxicol. 1986 Dec;24(12):651-4
 
Curcumin has gall-bladder emptying properties.
Asia Pac J Clin Nutr. 2002;11(4):314-8

Curcumin has potential in the treatment of plasma cell dyscrasias.
Biologics. 2008 Mar;2(1):161-3
 
Curcumin has significant therapeutic activity in patients with pancreatic cancer.
Clin Cancer Res. 2008 Jul 15;14(14):4491-9

Curcumin has therapeutic effects in idiopathic inflammatory orbital pseudotumours.
Phytother Res. 2000 Sep;14(6):443-7

Curcumin has therapeutic value in patients with monoclonal gammopathy, a possible precursor to multiple myeloma.
Clin Cancer Res. 2009 Sep 15;15(18):5917-22

Curcumin has therapeutic value in the treatment of recurrent anterior uveitis of different etiologies.
Clin Ophthalmol. 2010;4:1201-6

Curcumin improves ulcerative proctitis and Crohn's disease in patient s with inflammatory bowel disease.
Dig Dis Sci. 2005 Nov;50(11):2191-3

Curcumin induces programmed cell death and inhibits proinflammatory prostaglandin E2 production in synovial fibroblasts of patients with rheumatoid arthritis.
Int J Mol Med. 2007 Sep;20(3):365-72

Curcumin induces programmed cell death in human malignant gliobastoma cells - Article 2.
Neurosci Lett. 2006 Oct 16;407(1):53-8.

Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women.
Nutr Res. 2012 Oct ;32(10):795-9. Epub 2012 Oct 15

Curcumin is an effective treatment for HIV-associated diarrhea.
Dig Dis Sci. 2009 Oct;54(10):2188-91.

Curcumin is comparable to chlorhexidine as an anti-inflammatory mouthwash. Thus, it can be considered as an effective adjunct to mechanical periodontal therapy.
Oral Health Prev Dent. 2013 ;11(1):81-6.

Curcumin is safe and efficacious in treating major depressive disorder.
Phytother Res. 2013 Jul 6

Curcumin is safe in humans up to 8,000 mg/day when take by mouth for 3 months and has chemopreventive properties.
Anticancer Res. 2001 Jul-Aug;21(4B):2895-900.

Curcumin may enhance the therapeutic effect of gemcitabine in the treatment of advanced pancreatic cancer.
Curr Med Chem. 2009 Nov 24.

Curcumin may increase insulin production in healthy subjects.
Nutr J. 2010;9:43

Curcumin might have the potential to slow the disease process in patients with Monoclonal gammopathy...
Am J Hematol. 2012 May ;87(5):455-60.

Curcumin phytosome has a beneficial effect in diabetic microangiopathy.
Panminerva Med. 2011 Sep ;53(3 Suppl 1):43-9

Curcumin positively modulates blood lipids and reduces lipid peroxidation.
Arch Gerontol Geriatr. 2002 Feb;34(1):37-46

Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal.
Hum Exp Toxicol. 2010 Jan 7. Epub 2010 Jan 7

Curcumin reduces arsenic-induced DNA damage in human subjects.
Eur J Cancer Prev. 2011 Mar;20(2):123-31.

Curcumin selectively induces programmed cell death in cutaneous T-cell lymphoma cell lines and in peripheral blood mononuclear cells (PBMCs).
J Invest Dermatol. 2010 Aug;130(8):2110-9

Curcumin suppresses inflammation in the mucosa of children and adults with inflammatory bowel disease.
Br J Nutr. 2009 Nov 2:1-9.

Curcumin suppresses of phosphorylase kinase activity which is correlated to a resolution of psoriasis.
Br J Dermatol. 2000 Nov;143(5):937-49
 
Curcuminoids may be used to ameliorate oxidative damage in patients with beta-thalassemia/Hb E disease.
Clin Biochem. 2010 Mar;43(4-5):424-9

Curcuminoids reduce the frequency of acute myocardial infarction after coronary artery bypass grafting.
Am J Cardiol. 2012 Jul 1 ;110(1):40-4

Curry consumption improves cognitive function in the elderly.
Am J Epidemiol. 2006 Nov 1;164(9):898-906
 
Dietary turmeric reduces breath hydrogen indicating it may be of value for treating halitosis.
Dig Dis Sci. 2009 Aug;54(8):1725-9

Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people.
Nutr J. 2012 Sep 26 ;11(1):79


Dosage Study: A daily dose of 3.6 g of curcumin engendered 62% and 57% decreases in inducible PGE(2) production in blood samples...
Clin Cancer Res. 2004 Oct 15;10(20):6847-54.

Dosage Study: Turmeric extract can be administered safely to patients at doses of up to 2.2 g daily, equivalent to 180 mg of curcumin.
Clin Cancer Res. 2001 Jul;7(7):1894-900.

Early human safety study of turmeric oil (Curcuma longa oil) administered orally in healthy volunteers.
J Assoc Physicians India. 2003 Nov ;51:1055-60.

Early human safety study of turmeric oil (Curcuma longa oil) administered orally in healthy volunteers.
J Assoc Physicians India. 2003 Nov ;51:1055-60.

Fermented turmeric powder is well-tolerated and effective in subjects with elevated alanine transaminase levels.
BMC Complement Altern Med. 2013 ;13:58

High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus.
J Am Acad Dermatol. 2011 Sep 8

Lactoferrin and curcumin reduce infections in children with recurrent respiratory infections.
J Biol Regul Homeost Agents. 2009 Apr-Jun;23(2):119-24

Neem and Tumeric are a safe and effective topical treatment for scabies.
Trop Geogr Med. 1992 Jan;44(1-2):178-81.

Oral curcumin is safe and feasible in patients with pancreatic cancer.
Cancer Chemother Pharmacol. 2010 Sep 22. Epub 2010 Sep 22. PMID: 20859741

Oral curcumin may have therapeutic activity in the treatment of Déjérine-Sottas disease.
Pediatr Neurol. 2009 Oct;41(4):305-8. PMID: 19748054

Oral curcumin positively modulates blood lipid levels and lipid peroxidation.
Indian J Physiol Pharmacol. 1992 Oct;36(4):273-5. PMID: 1291482

Regular endurance exercise combined with daily curcumin ingestion may reduce LV afterload...
Am J Hypertens. 2012 Jun ;25(6):651-6. Epub 2012 Mar 15. PMID: 22421908

Review: Curcumin has therapeutic potential in multiple sclerosis.
Int Immunopharmacol. 2011 Mar;11(3):323-30. Epub 2010 Sep 8. PMID: 20828641

Safety & Dosage Review: Curcumin.
BMC Complement Altern Med. 2006;6:10. Epub 2006 Mar 17. PMID: 16545122

Soy isoflavones and curcumin suppress PSA levels in human subjects.
Prostate. 2010 Jul 1;70(10):1127-33. PMID: 20503397

The administration of low-dose curcumin showed a trend of reduction in total cholesterol level and LDL cholesterol...
Acta Med Indones. 2008 Oct;40(4):201-10. PMID: 19151449

The combination of curcumin and quercetin appears to reduce the number and size of ileal and rectal adenomas...
Clin Gastroenterol Hepatol. 2006 Aug;4(8):1035-8. Epub 2006 Jun 6. PMID: 16757216

Tumeric has an anti-mutagenic activity on urinary mutagens in smokers.
Mutagenesis. 1992 Mar;7(2):107-9. PMID: 1579064

Turmeric and curcumin are therapeutic as topical agents in cancer therapy.
Tumori. 1987 Feb 28;73(1):29-31. PMID: 2435036


Turmeric compares favorably to chlorhexidine gluconate mouthwash in the prevention of plaque formation and gingivitis.
J Contemp Dent Pract. 2011 ;12(4):221-4. Epub 2011 Jul 1. PMID: 22186854

Turmeric extract appears to be as safe and effective as ibuprofen for the treatment of knee osteoarthritis.
Int J Mol Med. 2010 May;25(5):729-34. PMID: 19678780

Turmeric extract supplementation prevents UVB-induced skin aging.
Phytomedicine. 2009 Jul 3. PMID: 19577913

Turmeric may be effective in treating lung diseases.
Adv Exp Med Biol. 2007;595:379-405. PMID: 17569221

Turmeric may improve irritable bowel syndrome.
J Altern Complement Med. 2004 Dec;10(6):1015-8. PMID:15673996

Vitamin D3 and curcuminoids (turmeric) stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients.
J Alzheimers Dis. 2009 Jul;17(3):703-17. PMID: 19433889

Curcumin extract for prevention of type 2 diabetes.
Diabetes Care. 2012 Nov ;35(11):2121-7. Epub 2012 Jul 6. PMID: 22773702

Curcumin has been used to successfully treat infantile hemangioendothelioma of the liver.
Pediatr Blood Cancer. 2010 Aug;55(2):377-9. PMID: 20582974

"A Novel Curcumin-based Vaginal Cream Vacurin Selectively Eliminates Apposed Human Cervical Cancer Cells.:
Gynecol Oncol. 2012 Dec 9. Epub 2012 Dec 9. PMID: 23234806

"Curcumin ameliorates cisplatin-induced nephrotoxicity by inhibiting renal inflammation in mice."
J Biosci Bioeng. 2012 Dec 12. Epub 2012 Dec 12. PMID: 23245727

"Curcumin Attenuates Diabetic Neuropathic Pain by Downregulating TNF-a in a Rat Model."
Int J Med Sci. 2013 ;10(4):377-81. Epub 2013 Feb 20. PMID: 23471081

"Curcumin combined with turmerones, essential oil components of turmeric, abolishes inflammation-associated mouse colon carcinogenesis."
Biofactors. 2012 Dec 11. Epub 2012 Dec 11. PMID: 23233214

"Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice.'
Brain. 2012 Dec ;135(Pt 12):3551-66. PMID: 23250879

"Curcumin protects against the oxidative damage induced by the pesticide parathion in the hippocampus of the rat brain."
Nutr Neurosci. 2012 Feb 2. Epub 2012 Feb 2. PMID: 22333997

A combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis.
Food Chem Toxicol. 2010 Jan;48(1):390-5. Epub 2009 Oct 25. PMID: 19861145

A combination of nutrients improves cognitive functioning while decreasing Alzheimer disease neuropathology in an animal model.
PLoS One. 2010;5(11):e14015. Epub 2010 Nov 17. PMID: 21103342

A combination of turmeric, clarified butter (ghee) and hyaluronic acid stimulates gingival wound healing following surgery.
J Ethnopharmacol. 2008 Dec 8;120(3):335-41. Epub 2008 Sep 20. PMID: 18929638

A combined dosage of tetrahydrocurcumin and chlorogenic acid protects against experimentally induced type 2 diabetes in rats.
Mol Cell Biochem. 2010 Aug;341(1-2):109-17. Epub 2010 Mar 26. PMID: 20339905

A curcumin complex reduces acute lung injury severity.
Am J Respir Cell Mol Biol. 2012 Feb 3. Epub 2012 Feb 3. PMID: 22312018

A curcumin derivative restores membrane homeostasis disrupted after brain trauma.
Exp Neurol. 2010 Nov;226(1):191-9. Epub 2010 Sep 15. PMID: 20816821

A curcumin-artemisinin combination is effective for malaria.
Antimicrob Agents Chemother. 2006 May;50(5):1859-60. PMID: 16641461

A curcumin-free water extract of turmeric prevents chemically-induced mammary cancer in rats.
Cancer Lett. 1998 Jan 16;123(1):35-40. PMID: 9461015

A curcumin-free water extract of turmeric prevents chemically-induced mammary cancer in rats.
Cancer Lett. 1998 Jan 16;123(1):35-40. PMID: 9461015

A curcumin-phospholipid complex works synergistically to protect the livers of rats following chemical exposure.
Int J Pharm. 2007 Feb 7;330(1-2):155-63. Epub 2006 Sep 23. PMID: 17112692

A fermented turmeric extract exhibits anti-obesity properties.
J Sci Food Agric. 2012 Jan 25. Epub 2012 Jan 25. PMID: 22278718

A multi-herbal product called Protandim exhibits chemopreventive properties in a mouse model of skin cancer.
PLoS One. 2010;5(7):e11902. Epub 2010 Jul 30. PMID: 20689586

A multi-herbal product called Protandim has chemopreventive properties against skin cancer.
PLoS One. 2009;4(4):e5284. Epub 2009 Apr 22. PMID: 19384424

Suppressor Protein p53 Upregulation : CK(163) : AC(105), Vascular Cell Adhesion Molecule-1 Inhibitor : CK(94) : AC(24)
A multi-herbal product called Protandim prevents fibrosis and capillary loss and preserves right ventricular function in rats.
Circulation. 2009 Nov 17;120(20):1951-60. Epub 2009 Nov 2. PMID: 19884466

A poly-herbal formula named Protandim reduces oxidative stress in a mouse model of Duchenne muscular dystrophy.
J Diet Suppl. 2010 Jun 1;7(2):159-178. PMID: 20740052

A polyherbal formula containing Sea buckthorn (H. rhamnoides), Aloe and Turmeric (C. longa) possesses significant wound healing potential in both normal as well as chronic diabetic wounds.
Wound Repair Regen. 2008 Nov-Dec;16(6):784-90. PMID: 19128249

Age may play a significant role in the efficacy of chemoprevention of colon cancer by curcumin.
Nutr Cancer. 2004;48(1):37-43. PMID: 15203376

Aloe vera, turmeric and holy basil suppress the adverse effects associated with maternal fluoride exposure.
Indian J Exp Biol. 2010 Aug;48(8):830-6. PMID: 21341542

Andrographis and Hedyotis corymbosa in combination with curcumin have anti-malaria action.
Phytother Res. 2004 Feb;18(2):164-8. PMID: 19216765

Bioavailability is enhanced with a curcumin-phosphatidylcholine complex.
J Pharm Biomed Anal. 2006 Feb 24;40(3):720-7. Epub 2005 Nov 28. PMID: 16316738

Bioavailability Study: Phosphatidyl choline bound curcumin is superior to curcumin in isolation.
J Pharm Sci. 2011 May;100(5):1987-95. Epub 2010 Nov 24. PMID: 21374628

Boswellic acid and curcumin have chemopreventive properties on chemically-induced oral cancer.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2011 Nov ;46(11):678-83. PMID: 22333308

Both curcumin and its metabolite tetrahydrocurcumin exert neuroprotection against chemically-induced neurotoxicity.
Inflammopharmacology. 2008 Apr;16(2):96-9. PMID: 18408903

Both curcumin and resveratrol show promise as anti-cachexia agents, whereas resveratrol performed better in this study.
Br J Cancer. 2004 Nov 1;91(9):1742-50. PMID: 15477867

Cadmium induced lipid peroxidation is abolished by curcumin treatment in the animal model.
Acta Neurol Scand Suppl. 1994;154:32-41. PMID: 15177643

Capsaicin and curcumin lower levels of an arthritis-associated glycoprotein in the sera of rats.
Mol Cell Biochem. 1997 Apr;169(1-2):125-34. PMID: 9089639

Carrageenan lambda type IV, cineole, curcumin, and eugenol provide significant protection in a mouse model of intravaginal HSV-2 challenge.
Antiviral Res. 1999 Jul;42(3):219-26. PMID: 10443534

Coenzyme Q10 and curcumin administration improves retinal histology by reversing the pathological changes due to chronic methanol...
J Med Assoc Thai. 2012 Apr ;95 Suppl 4:S76-81. PMID: 22696856

Combined curcumin and resveratrol reduces prostate cancer incidence in mice.
Int J Cancer. 2009 Jul 1;125(1):1-8. PMID: 19326431

Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on type 1 diabetic rats.
Gen Physiol Biophys. 2010 Mar;29(1):23-30. PMID: 20371877

Combining curcumin with guar gum may help increase its effectiveness in treating colon cancer.
Drugs Aging. 2007;24(11):945-55. PMID: 20614824

Compounds within turmeric suppress an increase in blood glucose levels in type 2 diabetic mice.
J Agric Food Chem. 2005 Feb 23;53(4):959-63. PMID: 15713005

Consumption of curcumin elevates fecal immunoglobulin A, an index of intestinal immune function, in rats fed a high-fat diet.
J Nutr Sci Vitaminol (Tokyo). 2010;56(1):68-71. PMID: 20354349

Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.
J Agric Food Chem. 2009 Sep 23;57(18):8587-90. PMID: 19711910

Cucuma longa (Turmeric) and Spikenard (N. jatamansi) elevates the HDL-cholesterol/total cholesterol ratio and lowers triglycerides.
Indian J Physiol Pharmacol. 1988 Oct-Dec;32(4):299-304. PMID: 3215683

Cucumin and piperine in combination have a potent antigenotoxic effect...
Toxicol Mech Methods. 2008 Jan;18(9):691-6. PMID: 20020926

Curcumin works synergistically with paclitaxel to inhibit breast cancer in a mouse model.
Breast J. 2009 May-Jun;15(3):223-9. PMID: 19645775

Curcumin (from Turmeric) ameliorates Diabetic Nephropathy in Rats.
Clin Exp Pharmacol Physiol. 2006 Oct;33(10):940-5. PMID: 17002671

Curcumin (from Turmeric) and kolaviron (a compound from the seeds of Garcinia kola) ameliorate phthalate-induced testicular damage in rats.
Basic Clin Pharmacol Toxicol. 2007 Jan;100(1):43-8. PMID: 17214610

Curcumin (from turmeric) and saikosaponin (from Bupleurum) protects against chemically induced liver fibrosis.
J Med Food. 2008 Jun;11(2):224-9. PMID: 18598162

Curcumin (from Turmeric) attenuates pulmonary inflammation and emphysema in mice.
Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L614-23. Epub 2009 Jan 23. PMID: 19168576

Curcumin (from turmeric) circumvents chemoresistance and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in mice.
Mol Cancer Ther. 2009 Apr;8(4):959-70. PMID: 19372569

Curcumin (from Turmeric) has a protective effect against Middle Cerebral Artery Occlusion (MCAO)
Neurochem Res. 2008 Jun;33(6):1036-43. Epub 2008 Jan 18. PMID: 18204970

Curcumin (from Turmeric) in combination with Piperine may attenuate stress-induced depression.
Pharmacol Biochem Behav. 2008 Oct 25. [Epub ahead of print] PMID: 19000708

Curcumin (from Turmeric) positively modulates the HPA axis and neurotrophin factor expression in chronically stressed animals.
Brain Res. 2006 Nov 29;1122(1):56-64. Epub 2006 Oct 3. PMID: 17022948

Curcumin (from Turmeric) reduces amyloid beta plaque formation in an animal model of Alzheimers disease.
Neurochem Int. 2009 Mar-Apr;54(3-4):199-204. Epub 2008 Nov 30. PMID: 15590663

Curcumin (from Turmeric) reduces oxidative damage and amyloid plaque in a transgenic animal model of Alzheimers.
J Neurosci. 2001 Nov 1;21(21):8370-7. PMID: 11606625

Curcumin (from Turmeric) reduces oxidative injury associated with idiopathic pulmonary fibrosis.
Zhongguo Zhong Yao Za Zhi. 2006 Apr;31(8):669-72. PMID: 16830828

Curcumin (Turmeric) may benefit Multiple Sclerosis by blocking an inflammatory mediator.
J Immunol. 2002 Jun 15;168(12):6506-13. PMID: 12055272

Curcumin acts as immunorestorer in tumor-bearing host.
Cancer Res. 2007 Jan 1;67(1):362-70. PMID: 17210719

Curcumin alleviates dystrophic muscle pathology in mdx mice.
Mol Cells. 2008 Jun 30;25(4):531-7. Epub 2008 May 6. PMID: 18460899

Curcumin alleviates matrix metalloproteinases associated with inflammation during eradication of H. pylori infection.
PLoS One. 2011;6(1):e16306. Epub 2011 Jan 21. PMID: 21283694

Curcumin ameliorates acute thioacetamide-induced hepatotoxicity.
J Gastroenterol Hepatol. 2006 Feb;21(2):358-66. PMID: 16509859

Curcumin ameliorates aflatoin-induced toxicity in serum of mice.
Acta Pol Pharm. 2008 May-Jun;65(3):339-43. PMID: 18646553

Curcumin ameliorates aflatoxin-induced changes in SDH and ATPase activities in liver and kidney of mice.
Acta Pol Pharm. 2008 Jul-Aug;65(4):415-9. PMID: 19051581

Curcumin ameliorates aflatoxin-induced lipid peroxidation in liver, kidney and testis of mice.
Acta Pol Pharm. 2007 Sep-Oct;64(5):413-6. PMID: 18540160

Curcumin ameliorates aflatoxin-induced lipid-peroxidation in liver and kidney of mice.
Acta Pol Pharm. 2008 Mar-Apr;65(2):195-202. PMID: 18666425

Curcumin ameliorates aflatoxin-induced toxicity in DNA, RNA and protein in liver and kidney of mice.
Acta Pol Pharm. 2007 Nov-Dec;64(6):497-502. PMID: 18323242

Curcumin ameliorates aflatoxin-induced toxicity in mice spermatozoa.
Fertil Steril. 2008 Sep;90(3):775-80. Epub 2007 Dec 27. PMID: 18163997

Curcumin ameliorates aflatoxin-induced toxicity.
Poult Sci. 2008 Jun;87(6):1125-30. PMID: 18493001

Curcumin ameliorates arterial dysfunction and oxidative stress with aging.
Exp Gerontol. 2012 Nov 7. Epub 2012 Nov 7. PMID: 23142245

Curcumin ameliorates chemically-induced liver damage and fibrosis in rats.
Ann Hepatol. 2011 Oct 1 ;10(4):516-30. PMID: 21911894

Curcumin ameliorates cognitive deficits and neurodegeneration in a rat model of sporadic dementia of Alzheimer's type (SDAT).
Eur Neuropsychopharmacol. 2009 Sep;19(9):636-47. Epub 2009 Mar 28. PMID: 19329286

Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats.
Eur J Pharmacol. 2010 Oct 10;644(1-3):106-12. Epub 2010 Jul 24. PMID: 20667451

Curcumin ameliorates endotoxin-induced experimental hepatoxicity in rodents.
Clin Exp Immunol. 2006 Aug;145(2):313-21. PMID: 16879252

Curcumin ameliorates ethanol and nonethanol experimental pancreatitis.
Am J Physiol Gastrointest Liver Physiol. 2003 Jan;284(1):G85-95. PMID: 12488237

Curcumin ameliorates experimentally induced ulcerative colitis.
Int Immunopharmacol. 2007 Mar;7(3):333-42. Epub 2006 Dec 18. PMID: 17276891

Curcumin ameliorates high glucose-induced adverse changes to the aortic endothelium of rats.
Clin Exp Pharmacol Physiol. 2009 Dec;36(12):1177-82. Epub 2009 May 19. PMID: 19473193

Curcumin ameliorates kidney failure in nephrectomized rats.
Am J Physiol Renal Physiol. 2009 May;296(5):F1146-57. Epub 2009 Feb 18. PMID: 19225048

Curcumin ameliorates kidney lesions associated with diabetes.
Mol Cell Biochem. 1998 Apr;181(1-2):87-96. PMID: 9562245

Curcumin ameliorates lung inflammation induced by Klebsiella pneumoniae and may be a useful adjuvant in antibiotic therapy.
J Med Microbiol. 2010 Jan 7. Epub 2010 Jan 7. PMID: 20056776

Curcumin ameliorates memory deficits associated with diabetes in the rat.
Age (Dordr). 2009 Mar;31(1):39-49. Epub 2008 Oct 8. PMID: 19234767

Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.
Int J Cancer. 2010 Sep 13. Epub 2010 Sep 13. PMID: 20839263

Curcumin ameliorates oxidative stress during nicotine-induced lung toxicity in rats.
Ital J Biochem. 2004 Jul;53(2):82-6. PMID: 15646012

Curcumin ameliorates sodium arsenite induced biochemical perturbations in rats.
Food Chem Toxicol. 2008 Nov;46(11):3506-11. Epub 2008 Sep 2. PMID: 18809455

Curcumin ameliorates sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs.
Molecules. 2009;14(3):1098-110. Epub 2009 Mar 10. PMID: 19049818

Curcumin ameloriates experimental autoimmune encephalomyelitis through inhibition of IL-17 production.
Int Immunopharmacol. 2009 May;9(5):575-81. Epub 2009 Feb 3. PMID: 19539560

Curcumin and tetrahydrocurcumin have antihyperlipidemic properties in experimental type 2 diabetic rats.
JPEN J Parenter Enteral Nutr. 1986 Sep-Oct;10(5):530-2. PMID: 17994458

Curcumin and a curcumin copper complex has a radioprotective effect in mouse livers.
J Radiat Res (Tokyo). 2007 May;48(3):241-5. Epub 2007 Apr 27. PMID: 17464095

Curcumin and caffeic acid phenethyl ester decrease intestinal tumors in an animal model of familial adenomatous polyposis.
Carcinogenesis. 2000 May;21(5):921-7. PMID: 10783313

Curcumin and CAPE may reduce chemotherapy-induced mucosal barrier injury.
Leukemia. 2004 Feb;18(2):276-84. PMID: 14671640

Curcumin ameliorates aflatoxin-induced lipid-peroxidation in liver and kidney of mice.
Acta Pol Pharm. 2008 Mar-Apr;65(2):195-202. PMID: 18666425

Curcumin ameliorates aflatoxin-induced toxicity in DNA, RNA and protein in liver and kidney of mice.
Acta Pol Pharm. 2007 Nov-Dec;64(6):497-502. PMID: 18323242

Curcumin ameliorates aflatoxin-induced toxicity in mice spermatozoa.
Fertil Steril. 2008 Sep;90(3):775-80. Epub 2007 Dec 27. PMID: 18163997

Curcumin ameliorates aflatoxin-induced toxicity.
Poult Sci. 2008 Jun;87(6):1125-30. PMID: 18493001

Curcumin ameliorates cognitive deficits and neurodegeneration in a rat model of sporadic dementia of Alzheimer's type (SDAT).
Eur Neuropsychopharmacol. 2009 Sep;19(9):636-47. Epub 2009 Mar 28. PMID: 19329286

Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats.
Eur J Pharmacol. 2010 Oct 10;644(1-3):106-12. Epub 2010 Jul 24. PMID: 20667451

Curcumin ameliorates endotoxin-induced experimental hepatoxicity in rodents.
Clin Exp Immunol. 2006 Aug;145(2):313-21. PMID: 16879252

Curcumin ameliorates ethanol and nonethanol experimental pancreatitis.
Am J Physiol Gastrointest Liver Physiol. 2003 Jan;284(1):G85-95. PMID: 12488237

Curcumin ameliorates experimentally induced ulcerative colitis.
Int Immunopharmacol. 2007 Mar;7(3):333-42. Epub 2006 Dec 18. PMID: 17276891

Curcumin ameliorates high glucose-induced adverse changes to the aortic endothelium of rats.
Clin Exp Pharmacol Physiol. 2009 Dec;36(12):1177-82. Epub 2009 May 19. PMID: 19473193

Curcumin ameliorates kidney failure in nephrectomized rats.
Am J Physiol Renal Physiol. 2009 May;296(5):F1146-57. Epub 2009 Feb 18. PMID: 19225048

Curcumin ameliorates kidney lesions associated with diabetes.
Mol Cell Biochem. 1998 Apr;181(1-2):87-96. PMID: 9562245

Curcumin ameliorates lung inflammation induced by Klebsiella pneumoniae and may be a useful adjuvant in antibiotic therapy.
J Med Microbiol. 2010 Jan 7. Epub 2010 Jan 7. PMID: 20056776

Curcumin ameliorates memory deficits associated with diabetes in the rat.
Age (Dordr). 2009 Mar;31(1):39-49. Epub 2008 Oct 8. PMID: 19234767

Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.
Int J Cancer. 2010 Sep 13. Epub 2010 Sep 13. PMID: 20839263

Curcumin ameliorates oxidative stress during nicotine-induced lung toxicity in rats.
Ital J Biochem. 2004 Jul;53(2):82-6. PMID: 15646012

Curcumin ameliorates sodium arsenite induced biochemical perturbations in rats.
Food Chem Toxicol. 2008 Nov;46(11):3506-11. Epub 2008 Sep 2. PMID: 18809455

Curcumin ameliorates sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs.
Molecules. 2009;14(3):1098-110. Epub 2009 Mar 10. PMID: 19049818

Curcumin ameloriates experimental autoimmune encephalomyelitis through inhibition of IL-17 production.
Int Immunopharmacol. 2009 May;9(5):575-81. Epub 2009 Feb 3. PMID: 19539560

Curcumin and tetrahydrocurcumin have antihyperlipidemic properties in experimental type 2 diabetic rats.
JPEN J Parenter Enteral Nutr. 1986 Sep-Oct;10(5):530-2. PMID: 17994458

Curcumin and a curcumin copper complex has a radioprotective effect in mouse livers.
J Radiat Res (Tokyo). 2007 May;48(3):241-5. Epub 2007 Apr 27. PMID: 17464095

Curcumin and caffeic acid phenethyl ester decrease intestinal tumors in an animal model of familial adenomatous polyposis.
Carcinogenesis. 2000 May;21(5):921-7. PMID: 10783313

Curcumin and CAPE may reduce chemotherapy-induced mucosal barrier injury.
Leukemia. 2004 Feb;18(2):276-84. PMID: 14671640

Curcumin attenuates acute adriamycin myocardial toxicity in rats.
Br J Pharmacol. 1998 Jun;124(3):425-7. PMID: 9647462

Curcumin attenuates airway hyperreactivity induced by ischemia-reperfusion of the pancreas in rats.
Transplant Proc. 2010 Apr;42(3):744-7. PMID: 20430162

Curcumin attenuates alcohol toxicity.
J Pharm Pharm Sci. 2004 Aug 20;7(2):274-83. Epub 2004 Aug 20. PMID: 15367386

Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs.
Biol Pharm Bull. 2003 Jul;26(7):1021-4. PMID: 12843631

Curcumin attenuates aluminum-induced functional neurotoxicity in rats.
Pharmacol Biochem Behav. 2009 Jul;93(1):31-9. Epub 2009 Apr 17. PMID: 19376155

Curcumin attenuates an inflammatory response and improved the meiotic maturation of oocytes...
Fiziol Zh. 2010;56(4):96-101. PMID: 20968042

Curcumin attenuates cadmium-induced tisse damage in mice.
J Appl Toxicol. 2006 May-Jun;26(3):207-12. PMID: 16345010

Curcumin attenuates cerebral edema following traumatic brain injury in mice.
J Neurochem. 2010 Feb 1. Epub 2010 Feb 1. PMID: 20132469

Curcumin attenuates chronic fatigue syndrome in a mouse experimental model.
Immunobiology. 2009;214(1):33-9. Epub 2008 Jun 17. PMID: 19159825

Curcumin attenuates Concanavalin A-induced liver injury in mice.
Int Immunopharmacol. 2012 Jan ;12(1):151-7. Epub 2011 Dec 2. PMID: 22138522

Anti-Inflammatory Agents : CK(1230) : AC(433), Hepatoprotective : CK(580) : AC(281)
Curcumin attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys.
BMC Pharmacol. 2005;5:15. Epub 2005 Oct 15. PMID: 16225695

Curcumin attenuates damage associated with cardiac ischemia/reperfusion.
J Surg Res. 2005 May 1;125(1):109-16. PMID: 15836859

Curcumin attenuates diabetic encephalopathy in rats.
Eur J Pharmacol. 2007 Dec 8;576(1-3):34-42. Epub 2007 Aug 14. PMID: 17822693

Curcumin attenuates diet-induced hypercholesterolemia in rats.
Med Sci Monit. 2005 Jul;11(7):BR228-234. Epub 2005 Jun 29. PMID: 15990684

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats.
Food Chem Toxicol. 2008 Apr;46(4):1279-87. Epub 2007 Sep 26. PMID: 18006204

Curcumin attenuates gentamicin-induced kidney oxidative damage in rats.
Food Chem Toxicol. 2006 Sep;44(9):1443-8. Epub 2006 May 20. PMID: 16814915

Curcumin attenuates high-fat-diet induced blood lipid elevation and oxidation.
Wei Sheng Yan Jiu. 2000 Jul;29(4):240-2. PMID: 12520931

Curcumin attenuates indomethacin-induced oxidative stress and mitochondrial dysfunction.
Arch Toxicol. 2008 Jul;82(7):471-81. Epub 2007 Nov 30. PMID: 18060385

Curcumin attenuates inflammation in experimental colitis.
Mol Cell Biochem. 2009 Feb;322(1-2):127-35. Epub 2008 Nov 11. PMID: 19002562

Curcumin attenuates ischemia-reperfusion injury in rat testis.
Fertil Steril. 2009 Jan;91(1):271-7. Epub 2008 Jan 28. PMID: 18222428

Curcumin attenuates isoproterenol induced myocardial necrosis in rats.
Mol Cell Biochem. 1999 Jul;197(1-2):31-7. PMID: 10485321

Curcumin attenuates lipopolysaccharide-induced renal inflammation.
Biol Pharm Bull. 2011;34(2):226-32. PMID: 21415532

Curcumin attenuates methotraxate-induced hepatic oxidative damage in rats.
J Egypt Natl Canc Inst. 2008 Jun;20(2):141-8. PMID: 20029470

Curcumin attenuates acute adriamycin myocardial toxicity in rats.
Br J Pharmacol. 1998 Jun;124(3):425-7. PMID: 9647462

Curcumin attenuates airway hyperreactivity induced by ischemia-reperfusion of the pancreas in rats.
Transplant Proc. 2010 Apr;42(3):744-7. PMID: 20430162

Curcumin attenuates alcohol toxicity.
J Pharm Pharm Sci. 2004 Aug 20;7(2):274-83. Epub 2004 Aug 20. PMID: 15367386

Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs.
Biol Pharm Bull. 2003 Jul;26(7):1021-4. PMID: 12843631

Curcumin attenuates aluminum-induced functional neurotoxicity in rats.
Pharmacol Biochem Behav. 2009 Jul;93(1):31-9. Epub 2009 Apr 17. PMID: 19376155

Curcumin attenuates an inflammatory response and improved the meiotic maturation of oocytes...
Fiziol Zh. 2010;56(4):96-101. PMID: 20968042

Curcumin attenuates cadmium-induced tisse damage in mice.
J Appl Toxicol. 2006 May-Jun;26(3):207-12. PMID: 16345010

Curcumin attenuates cerebral edema following traumatic brain injury in mice.
J Neurochem. 2010 Feb 1. Epub 2010 Feb 1. PMID: 20132469

Curcumin attenuates chemically induced colitis.
Am J Physiol Gastrointest Liver Physiol. 2003 Jul;285(1):G235-43. Epub 2003 Mar 13. PMID: 12637253

Curcumin attenuates chronic fatigue syndrome in a mouse experimental model.
Immunobiology. 2009;214(1):33-9. Epub 2008 Jun 17. PMID: 19159825

Curcumin attenuates Concanavalin A-induced liver injury in mice.
Int Immunopharmacol. 2012 Jan ;12(1):151-7. Epub 2011 Dec 2. PMID: 22138522

Curcumin attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys.
BMC Pharmacol. 2005;5:15. Epub 2005 Oct 15. PMID: 16225695

Curcumin attenuates damage associated with cardiac ischemia/reperfusion.
J Surg Res. 2005 May 1;125(1):109-16. PMID: 15836859

Curcumin attenuates diabetic encephalopathy in rats.
Eur J Pharmacol. 2007 Dec 8;576(1-3):34-42. Epub 2007 Aug 14. PMID: 17822693

Curcumin attenuates diet-induced hypercholesterolemia in rats.
Med Sci Monit. 2005 Jul;11(7):BR228-234. Epub 2005 Jun 29. PMID: 15990684

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats.
Food Chem Toxicol. 2008 Apr;46(4):1279-87. Epub 2007 Sep 26. PMID: 18006204

Curcumin attenuates gentamicin-induced kidney oxidative damage in rats.
Food Chem Toxicol. 2006 Sep;44(9):1443-8. Epub 2006 May 20. PMID: 16814915

Curcumin attenuates high-fat-diet induced blood lipid elevation and oxidation.
Wei Sheng Yan Jiu. 2000 Jul;29(4):240-2. PMID: 12520931

Curcumin attenuates indomethacin-induced oxidative stress and mitochondrial dysfunction.
Arch Toxicol. 2008 Jul;82(7):471-81. Epub 2007 Nov 30. PMID: 18060385

Curcumin attenuates inflammation in experimental colitis.
Mol Cell Biochem. 2009 Feb;322(1-2):127-35. Epub 2008 Nov 11. PMID: 19002562

Curcumin attenuates ischemia-reperfusion injury in rat testis.
Fertil Steril. 2009 Jan;91(1):271-7. Epub 2008 Jan 28. PMID: 18222428

Curcumin attenuates isoproterenol induced myocardial necrosis in rats.
Mol Cell Biochem. 1999 Jul;197(1-2):31-7. PMID: 10485321

Curcumin attenuates lipopolysaccharide-induced renal inflammation.
Biol Pharm Bull. 2011;34(2):226-32. PMID: 21415532

Curcumin attenuates methotraxate-induced hepatic oxidative damage in rats.
J Egypt Natl Canc Inst. 2008 Jun;20(2):141-8. PMID: 20029470

Curcumin attenuates acute adriamycin myocardial toxicity in rats.
Br J Pharmacol. 1998 Jun;124(3):425-7. PMID: 9647462

Curcumin attenuates airway hyperreactivity induced by ischemia-reperfusion of the pancreas in rats.
Transplant Proc. 2010 Apr;42(3):744-7. PMID: 20430162

Curcumin attenuates alcohol toxicity.
J Pharm Pharm Sci. 2004 Aug 20;7(2):274-83. Epub 2004 Aug 20. PMID: 15367386

Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs.
Biol Pharm Bull. 2003 Jul;26(7):1021-4. PMID: 12843631

Curcumin attenuates aluminum-induced functional neurotoxicity in rats.
Pharmacol Biochem Behav. 2009 Jul;93(1):31-9. Epub 2009 Apr 17. PMID: 19376155

Curcumin attenuates an inflammatory response and improved the meiotic maturation of oocytes...
Fiziol Zh. 2010;56(4):96-101. PMID: 20968042

Curcumin attenuates cadmium-induced tisse damage in mice.
J Appl Toxicol. 2006 May-Jun;26(3):207-12. PMID: 16345010

Curcumin attenuates cerebral edema following traumatic brain injury in mice.
J Neurochem. 2010 Feb 1. Epub 2010 Feb 1. PMID: 20132469

Curcumin attenuates chemically induced colitis.
Am J Physiol Gastrointest Liver Physiol. 2003 Jul;285(1):G235-43. Epub 2003 Mar 13. PMID: 12637253

Curcumin attenuates chronic fatigue syndrome in a mouse experimental model.
Immunobiology. 2009;214(1):33-9. Epub 2008 Jun 17. PMID: 19159825

Curcumin attenuates Concanavalin A-induced liver injury in mice.
Int Immunopharmacol. 2012 Jan ;12(1):151-7. Epub 2011 Dec 2. PMID: 22138522

Curcumin attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys.
BMC Pharmacol. 2005;5:15. Epub 2005 Oct 15. PMID: 16225695

Curcumin attenuates damage associated with cardiac ischemia/reperfusion.
J Surg Res. 2005 May 1;125(1):109-16. PMID: 15836859

Curcumin attenuates diabetic encephalopathy in rats.
Eur J Pharmacol. 2007 Dec 8;576(1-3):34-42. Epub 2007 Aug 14. PMID: 17822693

Curcumin attenuates diet-induced hypercholesterolemia in rats.
Med Sci Monit. 2005 Jul;11(7):BR228-234. Epub 2005 Jun 29. PMID: 15990684

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats.
Food Chem Toxicol. 2008 Apr;46(4):1279-87. Epub 2007 Sep 26. PMID: 18006204

Curcumin attenuates gentamicin-induced kidney oxidative damage in rats.
Food Chem Toxicol. 2006 Sep;44(9):1443-8. Epub 2006 May 20. PMID: 16814915

Curcumin attenuates high-fat-diet induced blood lipid elevation and oxidation.
Wei Sheng Yan Jiu. 2000 Jul;29(4):240-2. PMID: 12520931

Curcumin attenuates indomethacin-induced oxidative stress and mitochondrial dysfunction.
Arch Toxicol. 2008 Jul;82(7):471-81. Epub 2007 Nov 30. PMID: 18060385

Curcumin attenuates inflammation in experimental colitis.
Mol Cell Biochem. 2009 Feb;322(1-2):127-35. Epub 2008 Nov 11. PMID: 19002562

Curcumin attenuates ischemia-reperfusion injury in rat testis.
Fertil Steril. 2009 Jan;91(1):271-7. Epub 2008 Jan 28. PMID: 18222428

Curcumin attenuates isoproterenol induced myocardial necrosis in rats.
Mol Cell Biochem. 1999 Jul;197(1-2):31-7. PMID: 10485321

Curcumin attenuates lipopolysaccharide-induced renal inflammation.
Biol Pharm Bull. 2011;34(2):226-32. PMID: 21415532

Curcumin attenuates methotraxate-induced hepatic oxidative damage in rats.
J Egypt Natl Canc Inst. 2008 Jun;20(2):141-8. PMID: 20029470

Curcumin attenuates ovalbumin-induced airway inflammation.
Biochem Biophys Res Commun. 2008 Oct 17;375(2):275-9. Epub 2008 Aug 13. PMID: 18706396

Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA).
Mol Cell Biochem. 2009 Apr;324(1-2):157-64. Epub 2009 Jan 23. PMID: 19165575

Curcumin attenuates oxidative stress and inflammatory response in the early phase after partial hepatectomy...
J Surg Res. 2010 Mar;159(1):497-502. Epub 2008 Dec 31. PMID: 19321178

Curcumin attenuates renal fibrosis in rat obstructive nephropathy.
Urology. 2006 Feb;67(2):440-6. PMID: 16461119

Curcumin attenuates retinal oxidative stress and inflammation in diabetes.
Nutr Metab (Lond). 2007;4:8. Epub 2007 Apr 16. PMID: 17437639

Curcumin attenuates the development of allergic airway inflammation and hyper-responsiveness.
J Ethnopharmacol. 2010 Jul 17. Epub 2010 Jul 17. PMID: 20643202

Curcumin attenuates the inflammatory response in collagen-induced arthritis.

Int Immunopharmacol. 2010 May;10(5):605-10. Epub 2010 Feb 23. PMID: 20188213

Curcumin attenuates the kainic acid-induced hippocampal cell death in the mice.
Carcinogenesis. 2009 Nov;30(11):1949-56. Epub 2009 Sep 30. PMID: 17300872

Curcumin attenuates the organ dysfunction caused by endotoxemia in the rat.
Nutrition. 2008 Nov-Dec;24(11-12):1133-8. Epub 2008 Aug 26. PMID: 18752929

Curcumin attenuates the virulence of Pseudomonas aeruginosa .
J Agric Food Chem. 2008 Mar 26;56(6):1955-62. Epub 2008 Feb 20. PMID: 18284200

Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain.
Eur J Pharmacol. 2006 May 1;536(3):256-61. Epub 2006 Mar 13. PMID: 16584726

Curcumin attenuates vascular inflammation and cerebral vasospasm after subarachnoid hemorrhage in mice.
Antioxid Redox Signal. 2009 Jan;11(1):35-45. PMID: 18752423

Curcumin blocks chronic morphine analgesic tolerance and positively modulates brain chemistry.
Neuroreport. 2009 Jan 7;20(1):63-8. PMID: 19033880

Curcumin blocks fibrosis in anti-Thy 1 glomerulonephritis.
Kidney Int. 2005 Nov;68(5):2042-9. PMID: 16221204

Curcumin blocks HIV protease inhibitor rotonavir-induced vascular dysfunction in porcine coronary arteries.
J Am Coll Surg. 2005 Jun;200(6):820-30. PMID: 15922191

Curcumin blocks sepsis-induced muscle proteolysis.
Mediators Inflamm. 2008;2008:317851. PMID: 18389075

Curcumin can alleviate alveolitis and pulmonary fibrosis induced by bleomycin in rats.
Zhonghua Jie He He Hu Xi Za Zhi. 2007 Mar;30(3):197-201. PMID: 17572999

Curcumin can ameliorate cerebral pathological changes in the event of ischemic brain injury.
Nan Fang Yi Ke Da Xue Xue Bao. 2009 Jun;29(6):1153-5. PMID: 19726347

Curcumin can be an alternative therapy for protecting lung transplantation-associated injury...
Crit Care Med. 2008 Apr;36(4):1205-13. PMID: 18379247

Curcumin can decrease inflammation in an experimental model of fibrosis.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009 May;25(5):399-401. PMID: 19426594

Curcumin can decrease pulmonary arterial pressure, improve pulmonary vessel remodeling and inhibit the deposition of collagen I in pulmonary arterioles.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2006 Aug;22(3):257-61. PMID: 21158062

Curcumin can induce apoptosis of pulmonary fibroblasts in rats with bleomycin-induced pulmonary fibrosis.
Zhonghua Jie He He Hu Xi Za Zhi. 2009 Jan;32(1):37-41. PMID: 19484960

Curcumin can inhibit tumour growth in a xenograft animal model in vivo.
Phytother Res. 2010 Jan 13;24(2):189-192. Epub 2010 Jan 13. PMID: 20077433

Curcumin can reduce inflammation and offset some of the performance deficits associated with eccentric exercise-induced muscle damage.
Am J Physiol Regul Integr Comp Physiol. 2007 Jun;292(6):R2168-73. Epub 2007 Mar 1. PMID: 17332159

Curcumin can significantly protect neurons against cerebral ischemia.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2007 May;23(2):184-8. PMID: 21179765

Curcumin can stimulate developmental and adult hippocampal neurogenesis, and a biological activity that may enhance neural plasticity and repair.
J Clin Psychopharmacol. 2000 Dec;20(6):680-4. PMID: 18362141

Curcumin co-treatment seems to prevent oxidative damage and found to delay the development of cataract.
Indian J Exp Biol. 2004 Jun;42(6):601-3. PMID: 15260112

Curcumin compares favorably to the drug dexamethasone in a rat model of lung injury.
Cancer Lett. 2003 Mar 31;192(2):145-9. PMID: 18799504

Curcumin compares favorably with bisdemethoxycurcumin in a gastric ulcer model system.
Phytomedicine. 2009 Apr;16(4):342-51. Epub 2009 Feb 1. PMID: 19188055

Curcumin could improve cardiac function in heart failure.
Zhonghua Xin Xue Guan Bing Za Zhi. 2010 Apr;38(4):369-73. PMID: 20654087

Curcumin could improve heart function, diminish infarct size and reverse the abnormal changes in the activities of serum lactate dehydrogenase and creatine kinase MB in rats after myocardial infarction.
Pharmacol Res. 2010 Feb;61(2):142-8. Epub 2009 Sep 9. PMID: 19747544

Curcumin counteracts the aluminium-induced ageing-related alterations in the rat brain.
Biogerontology. 2009 Aug;10(4):489-502. Epub 2008 Nov 20. PMID: 19020987

Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.
Gastroenterology. 2006 Jan;130(1):120-6. PMID: 20622013

Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.
Int J Cancer. 2010 Sep 7. Epub 2010 Sep 7. PMID: 20824699

Curcumin demonstrates therapeutic properties in an animal model of Alzheimer disease.
J Pharmacol Exp Ther. 2008 Jul;326(1):196-208. Epub 2008 Apr 16. PMID: 18417733

Curcumin dispalys anti-proliferartive and anti-angiogenic properties on tumors.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Oct;35(10):1029-36. PMID: 21051827

Curcumin displays therapeutic value in an animal model of irritable bowel syndrome.
AAPS PharmSciTech. 2009;10(3):752-62. Epub 2009 Jun 3. PMID: 19495987

Curcumin eliminates leptin's effect on liver fibrogenesis.
Endocrinology. 2009 Jul;150(7):3011-20. Epub 2009 Mar 19. PMID: 19299451

Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells which are associated wtih liver fibrosis.
Lab Invest. 2009 Nov;89(11):1275-90. Epub 2009 Sep 7. PMID: 19736547

Curcumin enhances adriamycin-induced human liver-derived hepatoma G2 cell death.
Eur J Pharm Sci. 2011 Jun 14 ;43(3):125-31. Epub 2011 Apr 14. PMID: 21514382

Curcumin enhances neurogenesis and cognition in aged rats.
PLoS One. 2012 ;7(2):e31211. Epub 2012 Feb 16. PMID: 22359574

Curcumin enhances oral bioavailability and anti-tumor therapeutic efficacy of paclitaxel upon administration in nanoemulsion formulation.
PLoS One. 2010;5(10):e13264. Epub 2010 Oct 11. PMID: 20845461

Curcumin enhances the effect of cisplatin in suppression of head and neck squamous cell carcinoma.
Mol Cancer Ther. 2010 Oct;9(10):2665-75. PMID: 20937593

Curcumin enhances wound healing in animals.
Phytother Res. 2008 Jul;22(7):970-2. PMID: 9776860

Curcumin enhances wound healing in diabetic rats.
Wound Repair Regen. 1999 Sep-Oct;7(5):362-74. PMID: 10564565

Curcumin exerts an anti-hyperlipidemic effect against nicotine-induced lung toxicity...
J Med Food. 2005;8(2):246-50. PMID: 16117619

Curcumin exerts neuroprotective effects against homocysteine intracerebroventricular injection-induced cognitive impairment and oxidative stress in rat brain.
Exp Neurol. 2010 Oct;225(2):237-9. Epub 2010 Jul 11. PMID: 20553189

Curcumin exerts pain-killing effects in a mouse model of neuropathic pain.
Neuropharmacology. 2012 Feb ;62(2):843-54. Epub 2011 Sep 19. PMID: 21945716

Curcumin exerts stimulatory influence on the secretory function of the thyroid gland in young rats....
Folia Histochem Cytobiol. 2008;46(2):205-11. PMID: 18519239

Curcumin exhibits anti-bacterial activity against Helicobacter pylori infection.
Antimicrob Agents Chemother. 2009 Apr;53(4):1592-7. Epub 2009 Feb 9. PMID: 19204190

Curcumin exhibits anti-cancer activity in an animal mode of intestinal cancer.
Carcinogenesis. 2001 May;22(5):821-5. PMID: 11323404

Curcumin exhibits anti-gastrointestinal cancer activity in rats.
Cancer Sci. 2006 Sep;97(9):896-904. Epub 2006 Jun 29. PMID: 16805852

Curcumin exhibits anti-liver cancer activity.
Int J Pharm. 2010 Nov 15;400(1-2):211-20. Epub 2010 Sep 8. PMID: 20813175

Curcumin exhibits anti-malarial activity in a mouse model.
Biochem Biophys Res Commun. 2005 Jan 14;326(2):472-4. PMID: 15582601

Curcumin exhibits anti-melanoma activity.
Phytother Res. 2003 Mar;17(3):217-21. PMID: 19260281

Curcumin exhibits antidepressant properties.
Pharmacol Biochem Behav. 2005 Sep;82(1):200-6. PMID: 16171853

Curcumin exhibits chemopreventive properties in hematogenous breast cancer metastases in immunodeficient mice.
Cell Physiol Biochem. 2007;19(1-4):137-52. PMID: 17310108

Curcumin exhibits cholesterol lowering properties.
Nutr Res Pract. 2010 Jun;4(3):191-5. Epub 2010 Jun 28. PMID: 20607063

Curcumin exhibits hepatoprotective properties against selenium toxicity.
Indian J Physiol Pharmacol. 2005 Jan;49(1):111-4. PMID: 15881869

Curcumin exhibits inhibitory effects liver fibrosis associated with injury.
Am J Physiol Gastrointest Liver Physiol. 2003 Jul;285(1):G20-30. Epub 2003 Mar 26. PMID: 12660143

Curcumin exhibits neuroprotective properties when given 4h post-ischemia in the rat thromboembolic stroke models.
Behav Brain Res. 2008 Nov 21;193(2):289-97. Epub 2008 Jun 19. PMID: 18611416

Curcumin exhibits potentially therapeutic properties in a rat experimental model of endometriosis.
Maturitas. 2007 Mar 20;56(3):322-31. Epub 2006 Nov 13. PMID: 21069258

Curcumin exhibits radioprotective properties and inhibits acute and chronic effects of gamma radiation exposure.
Int J Radiat Oncol Biol Phys. 2002 Jul 1;53(3):735-43. PMID: 12062620

Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster.
Planta Med. 1997 Oct;63(5):465-6. PMID: 20645870

Curcumin extends lifespan in Caenorhabditis elegans.
Mech Ageing Dev. 2011 Aug 9. Epub 2011 Aug 9. PMID: 21855561

Curcumin formulated with phosphatidylcholine furnishes higher systemic levels of parent agent than unformulated curcumin.
Cancer Chemother Pharmacol. 2007 Jul;60(2):171-7. Epub 2006 Oct 19. PMID: 17051370

Curcumin has a beneficial effect on acute lung injury induced by oleic acid in rats.
Zhongguo Zhong Yao Za Zhi. 2008 Sep;33(17):2141-5. PMID: 19066061
Indian J Pharmacol. 2012 Jan ;44(1):73-7. PMID: 22345874

Curcumin has a cardioprotective effect against myocardial ischemia.
Int J Biochem Cell Biol. 2004 Oct;36(10):1967-80. PMID: 15203111

Curcumin has a chemopreventive effect on chemically-induced esophageal cancer.
Jpn J Cancer Res. 2000 Sep;91(9):893-8. PMID: 11011116

Curcumin has a corrective effect on the expression of genetic defects associated with cystic fibrosis in an animal model.
Lab Invest. 2010 May 10. Epub 2010 May 10. PMID: 15105504

Curcumin has a curative effect on liver fibrosis in rats.
Zhong Yao Cai. 2007 Nov;30(11):1421-5 PMID: 18323214

Curcumin has a cytoprotective and immunomodulating effect in rats subjected to carbon tetrachloride-induced oxidative stress.
Br J Rheumatol. 1994 Sep;33(9):847-52. PMID: 18340409

Curcumin has a detoxifiying and antioxidant effect in rats experimentallly exposed to mercury.
Cont Lens Anterior Eye. 2009 Dec 21. Epub 2009 Dec 21. PMID: 20229497

Curcumin has a immunomodulatory effect in host macrophages and NK cells which results in a tumoricidal effect.
FEBS Lett. 2000 Oct 13;483(1):78-82. PMID: 11033360

Curcumin has a liver protecting effect against aflatoxin B(1)-induced liver injury.
Arch Toxicol. 2010 May;84(5):389-96. Epub 2010 Jan 30. PMID: 20112103

Curcumin has a neuroprotective effect against homocysteine-induced cognitive impairment and oxidative stress in the rat.
Pharmacol Biochem Behav. 2010 Oct;96(4):378-85. Epub 2010 Jul 6. PMID: 20619287

Curcumin has a neuroprotective effect in arsenic-induced neurotoxicity in rats.
Neurotoxicology. 2010 Sep;31(5):533-9. Epub 2010 May 11. PMID: 20466022

Curcumin has a neuroprotective effect in brain trauma.
Neuroscience. 2009 Jul 21;161(4):1037-44. Epub 2009 Apr 21. PMID: 19393301

Curcumin has a neuroprotective effect in hypoxia ischemia brain tissue injury.
J Nat Prod. 2009 Apr;72(4):725-31. PMID: 19397204

Curcumin has a neuroprotective effect in in middle cerebral artery occlusion induced focal cerebral ischemia in rats.
Life Sci. 2004 Jan 9;74(8):969-85. PMID: 14672754

Curcumin has a neuroprotective effect on 6-hydroxydopamine-induced Parkinsonism in rats.
Exp Neurol. 2010 Oct;225(2):237-9. Epub 2010 Jul 11. PMID: 20951685

Curcumin has a neuroprotective effect on focal cerebral ischemic rats by preventing blood-brain barrier damage.
Chemotherapy. 2010;56(1):60-5. Epub 2010 Mar 19. PMID: 17303117

Curcumin has a novel synergistic effect with the drug cyclosporine as an immunosuppressive.
Transplant Proc. 2003 Jun;35(4):1603-5. PMID: 12826232

Curcumin has a palliative action on gentamicin-induced nephrotoxicity in rats.
Fundam Clin Pharmacol. 2005 Aug;19(4):473-7. PMID: 16011735

Curcumin has a potent preventive action against radiation-induced breast cancer initiation.
Carcinogenesis. 2000 Oct;21(10):1835-41. PMID: 11023541

Curcumin has a potent preventive activity during the DES-dependent promotion stage of radiation-induced mammary tumorigenesis.
Carcinogenesis. 1999 Jun;20(6):1011-8. PMID: 10357781

Curcumin has a preventive effect on different aspiration material-induced lung injury in rats.
Pediatr Surg Int. 2009 Jan;25(1):83-92. Epub 2008 Nov 12. PMID: 19002695

Curcumin has a preventive effect on experimental acute pancreatitis in mouse.
Indian J Med Res. 2011 Nov ;134(5):717-24. PMID: 22199113

Curcumin has a prophylactic effect on hepatic fibrosis.
Zhonghua Gan Zang Bing Za Zhi. 2006 May;14(5):337-40. PMID: 16732906

Curcumin has a protective effect after spinal cord injury.
J Surg Res. 2009 Aug 5. Epub 2009 Aug 5. PMID: 20018302

Curcumin has a protective effect against against intracerebral streptozotocin induced impairment in memory and cerebral blood flow.
Life Sci. 2010 Jan 16;86(3-4):87-94. Epub 2009 Nov 17. PMID: 19925811

Curcumin has a protective effect against aluminium toxicity in rats as measured by behavioral and biochemical alterations.
Behav Brain Res. 2009 Jul 16. PMID: 19616038

Curcumin has a protective effect against hyperlipidemia and insulin resistance in high-fat-fed hamsters.
J Am Diet Assoc. 2005 Jun;105(6):967-70. PMID: 18940397

Curcumin has a protective effect against lsoproterenol-induced mycardial infarction.
Biochem Pharmacol. 1996 Jan 12;51(1):47-51. PMID: 8534267

Curcumin has a protective effect against nicotine-induced genotoxicity on rat liver.
Eur J Pharmacol. 2008 Jul 7;588(2-3):151-7. Epub 2008 Apr 15. PMID: 18508046

Curcumin has a protective effect in experimentally induced colitis.
Br J Pharmacol. 2003 May;139(2):209-18. PMID: 12770926

Curcumin has a protective effect on experimentally induced inflammation, hepatotoxicity and cardiotoxicity in rats.
Exp Toxicol Pathol. 2010 Apr 2. Epub 2010 Apr 2. PMID: 20363603

Curcumin has a protective effect on lindane induced reproductive toxicity in male Wistar rats.
Bull Environ Contam Toxicol. 2010 Apr;84(4):378-84. Epub 2010 Feb 25. PMID: 20182699

Curcumin has a protective effect on myocardial ischemia reperfusion injury.
Zhong Yao Cai. 2005 Oct;28(10):920-2. PMID: 16479932

Curcumin has a similar effect to hydrocortisone in preventing bleomycin-induced pulmonary fibrosis.
J Ethnopharmacol. 2007 Jun 13;112(2):292-9. Epub 2007 Mar 13. PMID: 17434272

Curcumin has a synergistic effect with cisplatin against fibrosarcoma.
Pharmacol Res. 1999 Mar;39(3):175-9. PMID: 10094841

Curcumin has an ameliorative effect against acute cadmium toxicity on male reproductive system in rats.
Andrologia. 2012 Jan 18. Epub 2012 Jan 18. PMID: 22257170

Curcumin has an ameliorative effect on the seminiferous epithelium metronidazole-treated mice.
Toxicol Pathol. 2010;38(3):366-71. Epub 2010 Mar 9. PMID: 20215582

Curcumin has an insulin releasing effect in rat-isolated pancreatic islets.
Angiology. 2010 Aug;61(6):557-66. Epub 2010 Apr 14. PMID: 20395228

Curcumin has analgesic properties.
Phytother Res. 2009 Apr;23(4):507-12. PMID: 19051211

Curcumin has analgesic properties.
Pak J Biol Sci. 2008 Jan 15;11(2):312-4. PMID: 18817212

Curcumin has anti-aging and neuroprotective effects in aged rat brain regions.
Biogerontology. 2006 Apr;7(2):81-9. PMID: 16802111

Curcumin has anti-anxiety properties.
Brain Res. 2010 Sep 17;1352:167-75. Epub 2010 Jul 12. PMID: 20633542

Curcumin has anti-cataractogenic properties.
Chem Biol Interact. 2009 Oct 7;181(2):202-9. Epub 2009 May 27. PMID: 19481068

Curcumin has anti-thrombotic properties.
Biochem Pharmacol. 1999 Oct 1;58(7):1167-72. PMID: 10484074

Curcumin has anti-ulcer activity in experimental gastric ulcer in rats.
Biomed Environ Sci. 2009 Dec;22(6):488-95. PMID: 20337222

Curcumin has anti-umorigenic and hormone-suppressive effects against pituitary tumors.
Endocr Relat Cancer. 2009 Dec;16(4):1339-50. Epub 2009 Sep 2. PMID: 19726538

Curcumin has anticancer, chemosensitization and radiosensitization effects in prostate cancer.
Cancer Res. 2007 Mar 1;67(5):1988-96. PMID: 17332326

Curcumin has anticonvulsant activity on increasing current electroshock seizures in mice.
Phytother Res. 2008 Dec;22(12):1660-4. PMID: 18661468

Curcumin has antidepressant properties that compare favorably to the drugs imipramine and fluoxetine.
Acta Pol Pharm. 2011 Sep-Oct;68(5):769-75. PMID: 21928724

Curcumin has antidepressant-like effects in chronic unpredictable mild stress of rats.
Prog Neuropsychopharmacol Biol Psychiatry. 2009 Apr 30;33(3):435-49. Epub 2009 Jan 22. PMID: 19302828


Curcumin has antihyperalgesic properties.
J Dent Res. 2010 Feb;89(2):170-4. Epub 2009 Dec 29. PMID: 20040737

Curcumin has antinociceptive (pain-killing) properties associated with ATP-sensitive potassium channels.
Korean J Pain. 2012 Oct ;25(4):221-7. Epub 2012 Oct 4. PMID: 23091682

Curcumin has beneficial effects in experimental dementia.
Naunyn Schmiedebergs Arch Pharmacol. 2010 Jun;381(6):529-39. Epub 2010 Apr 6. PMID: 20369229
 Jun 01, 2010

Curcumin has chemopreventive properties during the promotion/progression stages of colon cancer.
Cancer Res. 1999 Feb 1;59(3):597-601. PMID: 9973206

Curcumin has lipid lowering properties in diabetic rats.
Mol Cell Biochem. 1997 Jan;166(1-2):169-75. PMID: 9046034

Curcumin has neuroprotective effect on transient focal cerebral ischemia in rats.
Brain Res. 2008 Sep 10;1229:224-32. Epub 2008 Jul 8. PMID: 18640105

Curcumin has neuroprotective effects against a fungal toxin.
Methods Find Exp Clin Pharmacol. 2007 Jan-Feb;29(1):19-25. PMID: 17344940

Curcumin has positive immunomodulatory effects on mouse schistosomiasis.
Immunobiology. 2009;214(8):712-27. Epub 2009 Feb 26. PMID: 19249123

Curcumin has potent liver preservation properties in an isolated perfusion model.
Transplantation. 2006 Oct 15;82(7):931-7. PMID: 17038909

Curcumin has potent therapeutic activity in the amelioration of alcoholic neuropathy in rats.
Neurosci Lett. 2012 Jan 16. Epub 2012 Jan 16. PMID: 22281447

Curcumin has potential anti-epileptic effects.
Indian J Physiol Pharmacol. 2009 Jan-Mar;53(1):39-46. PMID: 19810575

Curcumin has protective effects against hepatic ischemia/reperfusion injury.
World J Gastroenterol. 2007 Apr 7;13(13):1953-61. PMID: 17461496

Curcumin has schistosomicidal potential against Schistosoma japonicum.
J Asian Nat Prod Res. 2012 Oct 23. Epub 2012 Oct 23. PMID: 23088385

Curcumin has therapeutic effects in chemically-induced colitis.
World J Gastroenterol. 2006 Jun 28;12(24):3848-53. PMID: 16804969

Curcumin has variable immunomodulatory effects.
J Huazhong Univ Sci Technolog Med Sci. 2005;25(2):137-40. PMID: 16116955

Curcumin holds promise as an agent to prevent or treat central nervous system complications in diabetes.
J Biomed Sci. 2010;17:43. Epub 2010 May 31. PMID: 20513244

Curcumin improves bone microarchitecture and enhances mineral density in transgenic mice.
Phytomedicine. 2011 Jan 15;18(2-3):205-13. Epub 2010 Jul 16. PMID: 20637579

Curcumin improves early functional results after experimental spinal cord injury.
Acta Neurochir (Wien). 2010 Sep;152(9):1583-90; discussion 1590. Epub 2010 Jun 10. PMID: 20535508

Curcumin improves insulin resistance in skeletal muscle of rats.
Nutr Metab Cardiovasc Dis. 2010 Mar 12. Epub 2010 Mar 12. PMID: 20227862

Curcumin improves learning and memory ability in a mouse Alzheimer's disease experimental model.
Chin Med J (Engl). 2008 May 5;121(9):832-9. PMID: 18701050

Curcumin improves left ventricular function in pressure overloaded rabbits.
Biol Pharm Bull. 2004 Feb;27(2):198-202. PMID: 14758033

Curcumin improves memory and learning dysfunction in rats.
Eur J Gastroenterol Hepatol. 2002 Nov;14(11):1271-4. PMID: 18394334

Curcumin improves outcomes and attenuates focal cerebral ischemic injury.
Neurochem Res. 2010 Mar;35(3):374-9. Epub 2009 Sep 23. PMID: 19774461

Curcumin improves sclerosing cholangitis in mice.
Gut. 2010 Apr;59(4):521-30. PMID: 20332524

Curcumin improves spatial memory impairment induced by human immunodeficiency virus type 1 in rats.
Life Sci. 2009 Jul 3;85(1-2):1-10. Epub 2009 Apr 5. PMID: 19345695

Curcumin improves survival in mice with tumors.
Tohoku J Exp Med. 2002 Aug;197(4):221-7. PMID: 12434997

Curcumin improves the metabolic status in diabetic conditions.
Phytother Res. 2007 Apr;21(4):395-7. PMID: 8609907

Curcumin improves vascular function and alleviates oxidative stress in endotoxaemia in mice.
J Clin Invest. 2008 Mar;118(3):868-78. PMID: 19540224

Curcumin improves wound healing by modulating collagen and decreasing reactive oxygen species.
Cancer Lett.2006 Jul 28;239(1):144-50. Epub 2005 Nov 21 PMID: 16770527

Curcumin in combination with EPA and DHA work synergistically to reduce inflammation.
Biochem Pharmacol. 2010 Feb 1;79(3):421-30. Epub 2009 Sep 8. PMID: 19744468

Curcumin in combination with visible light inhibits tumor growth in a xenograft tumor model.
Int J Cancer. 2009 Mar 15;124(6):1422-8. PMID: 19035461

Curcumin increases glucose uptake in skeletal muscle.
Neurosci Lett. 2009 Nov 20;465(3):238-41. Epub 2009 Sep 16. PMID: 19765405

Curcumin induces a tolerogenic response in an animal model of colitis.
Eur J Immunol. 2009 Nov;39(11):3134-46. PMID: 19839007

Curcumin induces programmed cell death and inhibits growth of human Burkitt's lymphoma in xenograft mouse model.
J Nutr. 2009 Jul;139(7):1339-46. Epub 2009 Jun 3. PMID: 19326074

Curcumin induces recovery from hepatic injury.
Indian J Biochem Biophys. 2008 Oct;45(5):317-25. PMID: 19069843

Curcumin inhibit tumor promoter-induced reactive oxygen species generation in leukocytes in vitro and in vivo.
Jpn J Cancer Res. 1998 Apr;89(4):361-70. PMID: 9617340

Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease...
Transl Neurodegener. 2012 ;1(1):16. Epub 2012 Aug 20. PMID: 23210631

Curcumin inhibits adenoid cystic carcinoma.
Mol Pharmacol. 2010 Oct 19. Epub 2010 Oct 19. PMID: 20959361

Curcumin inhibits amyloid-petpide induced changes associated with the progression of Alzheimer's disease.
J Neurochem. 2004 Dec;91(5):1199-210. PMID: 15569263

Curcumin inhibits ascites tumor growth in mice.
Mol Cell Biochem. 2005 May;273(1-2):57-67. PMID: 16013440

Curcumin inhibits bladder tumor growth in a mouse model.
Int Braz J Urol. 2009 Sep-Oct;35(5):599-606; discussion 606-7. PMID: 19860939

Curcumin inhibits bleomycin-induced pulmonary fibrosis in rats.
Br J Pharmacol. 2000 Sep;131(2):169-72. PMID: 10991907

Curcumin inhibits chemically-induced colonic lesions.
Carcinogenesis. 1993 Nov;14(11):2219-25. PMID: 8242846

Curcumin inhibits chemically-induced liver cancer.
Food Chem Toxicol. 2000 Nov;38(11):991-5. PMID: 11038236

Curcumin inhibits chemically-induced skin cancer promotion in the mouse model.
Cancer Res. 2010 Aug 1;70(15):6368-76. Epub 2010 Jul 20. PMID: 3139287

Curcumin inhibits chemically-induced skin cancer.
Cancer Lett. 1994 Nov 25;87(1):85-9. PMID: 7954373

Curcumin inhibits chemically-induced tumor initiation.
Carcinogenesis. 1992 Nov;13(11):2183-6. PMID: 1423891

Curcumin inhibits colon polyp formation.
Br J Cancer. 2003 May 6;88(9):1480-3. PMID: 12778080

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice.
Carcinogenesis. 2009 Nov;30(11):1949-56. Epub 2009 Sep 30. PMID: 19793800

Curcumin inhibits endometrial cancer and works synergistically with the aromatase inhibitor letrozole.
Int J Gynecol Cancer. 2009 Oct;19(7):1248-52. PMID: 19823063

Curcumin inhibits experimental collitis via anti-angiogenic and anti-inflammatory properties.
J Pharm Pharmacol. 2009 Mar;61(3):311-21. PMID: 19222903

Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury.
Am J Physiol Lung Cell Mol Physiol. 2010 Jan 8. Epub 2010 Jan 8. PMID: 20061443

Curcumin inhibits HMGB1 releasing and attenuates concanavalin A-induced hepatitis in mice.
Eur J Pharmacol. 2012 Oct 11. Epub 2012 Oct 11. PMID: 23063543

Curcumin Inhibits Imiquimod-Induced Psoriasis-Like Inflammation by Inhibiting IL-1beta and IL-6 Production in Mice.
PLoS One. 2013 ;8(6):e67078. Epub 2013 Jun 25. PMID: 23825622

Curcumin inhibits leukemia cells in mice.
In Vivo. 2008 Jan-Feb;22(1):63-8. PMID: 18396784

Curcumin inhibits lipid peroxidation and cholesterol levels in mice.
Indian J Physiol Pharmacol. 1992 Oct;36(4):239-43. PMID: 1291474

Curcumin inhibits liver fibrosis.
J Pharm Pharmacol. 2002 Jan;54(1):119-26. PMID: 11829122

Curcumin inhibits liver injury in a mouse model of endotoxemic shock.
Biotechnol Lett. 2010 Feb;32(2):209-14. Epub 2009 Oct 25. PMID: 19856147

Curcumin inhibits lung cancer cell metastasis.
Clin Exp Metastasis. 2000;18(7):539-45. PMID: 11688958

Curcumin inhibits muscle wasting in colon tumor bearing mice.
Br J Nutr. 2009 Oct;102(7):967-75. Epub 2009 Apr 27. PMID: 19393114

Curcumin inhibits NF-kappaB activation and reduces the severity of experimental fatty liver in mice.
Mech Ageing Dev. 2003 Dec;124(10-12):1025-34. PMID: 15582125

Curcumin inhibits nitric oxide production.
Biochem Pharmacol. 1998 Jun 15;55(12):1955-62. PMID: 9714315

Curcumin inhibits proliferation and induces programmed cell death in leukemic cells...
 and prolongs survival of mice with acute lymphoblastic leukemia.
J Agric Food Chem. 2008 Sep 24;56(18):8418-26. Epub 2008 Aug 30. PMID: 19055861

Curcumin inhibits prostate cancer growth.
Prostate. 2001 Jun 1;47(4):293-303. PMID: 11398177

Curcumin inhibits prostate cancer tumors.
Peptides. 2009 Dec;30(12):2357-64. Epub 2009 Sep 20. PMID: 19772879

Curcumin inhibits radiation-impaired healing of excisional wounds in mice.
J Wound Care. 2004 Mar;13(3):107-9. PMID: 15045805

Curcumin inhibits radiation-induced changes in the liver.
J Radiol Prot. 2001 Dec;21(4):361-70. PMID: 11787891

Curcumin inhibits reactive oxygen species formation and vascular hyperpermeability following haemorrhagic shock.
Clin Exp Pharmacol Physiol. 2010 Sep;37(9):939-44. Epub 2010 May 28. PMID: 20528978

Curcumin inhibits the growth of choroidal melanoma.
Cancer Biol Ther. 2011 Jan 15;11(2):229-35. Epub 2011 Jan 15. PMID: 21084858

Curcumin inhibits the growth of HTLV-1 infected T-cell tumors implanted into mice...
Int J Cancer. 2006 Feb 1;118(3):765-72. PMID: 16106398

Curcumin inhibits the growth of pancreatic cancer in a mouse experimental model.
Anticancer Res. 2009 Jun;29(6):1895-9. PMID: 19528445

Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus
Eur J Pharmacol. 2008 Sep 28;593(1-3):105-11. Epub 2008 Jul 15. PMID: 18664365

Curcumin inhibits the proliferation of human oral cancer cells.
Am J Chin Med. 2010;38(2):343-58. PMID: 20387230

Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo.
Cancer Res. 2008 Sep 15;68(18):7283-92. PMID: 18794115

Curcumin inhibits trinitrobenzene sulphonic acid-induced colitis in rats.
Int Immunopharmacol. 2006 Aug;6(8):1233-42. Epub 2006 Apr 7. PMID: 16782535

Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts.
Mol Nutr Food Res. 2010 Aug;54(8):1192-201. PMID: 20087857

Curcumin inhibits tumor implantation and growth in the mouse bladder tumor model.
J Urol. 2001 Oct;166(4):1498-501. PMID: 11547120

Curcumin inhibits tumorigenesis in mice.
Phytother Res. 2009 Nov;23(11):1524-30. PMID: 9591190

Curcumin intervention ameliorates the AFB(1) induced toxicity.
J Ethnopharmacol. 2010 Feb 17;127(3):641-4. Epub 2009 Dec 14. PMID: 20015472
 Feb 17, 2010

Curcumin is a potential glucose-lowering agent and antioxidant in type 2 diabetic mice.
Phytother Res. 2008 Feb;22(2):180-4. PMID: 18398869

Curcumin is a potential radio-enhancer in head and neck cancer.
Laryngoscope. 2009 Oct;119(10):2019-26. PMID: 19655336

Curcumin is an in vivo inhibitor of angiogenesis.
Mol Med. 1998 Jun;4(6):376-83. PMID: 10780880

Curcumin is effective in the prevention of radiation-induced oral mucositis.
Int J Radiat Biol. 2004 Feb;80(2):177-82. PMID: 15164799

Curcumin is efficacious for chronic nonbacterial prostatitis in rats.
Zhonghua Nan Ke Xue. 2010 Jan;16(1):84-8. PMID: 20180411 Jan 01, 2010

Curcumin is more effective than prednisone at suppressing bleomycin-induced pulmonary fibrosis in rats.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2008 May;26(5):257-61. PMID: 18727865

Curcumin is protective against phenytoin-induced cognitive impairment and oxidative stress in rats.
Brain Res. 2009 Dec 8;1301:52-60. Epub 2009 Sep 16. PMID: 19765566

Curcumin is superior to drug therapies for preventing scopolamine-induced memory impairment.
Fitoterapia. 2011 Jan 26. Epub 2011 Jan 26. PMID: 21277954

Curcumin limits the fibrogenic evolution of experimental fatty liver.
Lab Invest. 2010 Jan;90(1):104-15. Epub 2009 Nov 9. PMID: 19901911

curcumin may be an effective strategy to combat the genotoxicity of arsenic.
Asian Pac J Cancer Prev. 2010;11(1):239-47. PMID: 20593964

Curcumin may be useful as an angiogenic inhibitor in the treatment of corneal diseases that show neovascularization.
Ophthalmologica. 2008;222(3):178-86. Epub 2008 May 22. PMID: 18497527

Curcumin may contribute to ameliorating alcohol withdrawal symptoms.
Cell Mol Neurobiol. 2007 Dec;27(8):997-1006. Epub 2007 Sep 11. PMID: 17846884

Curcumin may contribute to preventing memory loss.
Biochem Pharmacol. 2009 Apr 1;77(7):1254-65. Epub 2008 Dec 31. PMID: 19161989

Curcumin may have a beneficial effect in degenerative aortic aneurysms.
Ann Vasc Surg. 2006 May;20(3):360-8. Epub 2006 May 19. PMID: 16779518

Curcumin may have a preventive role in the treatment of diabetic retinopathy.
Biochem Biophys Res Commun. 2007 Sep 21;361(2):528-32. Epub 2007 Jul 23. PMID: 17662242

Curcumin may have a therapeutic role in reducing the adverse effects of hyperandrogenemia on the ovary and metabolism.
Reprod Sci. 2009 Jun;16(6):539-50. Epub 2009 Mar 20. PMID: 19304795

Curcumin may have beneficial anti-angiogenic and protective properties in kidneys of diabetics.
J Med Assoc Thai. 2010 Feb;93 Suppl 2:S1-8. PMID: 21302394

Curcumin may have therapeutic value for controlling allergic responses resulting from exposure to allergens such as latex.
Clin Mol Allergy. 2007;5:1. Epub 2007 Jan 25. PMID: 17254346

Curcumin may have therapeutic value for treatment of diabetes-associated hepatic fibrogenesis.
Mol Cell Endocrinol. 2010 Dec 30. Epub 2010 Dec 30. PMID: 21195127

Curcumin may have therapeutic value in Alzheimer disease prevention.
Cancer Lett. 2009 Nov 24. Epub 2009 Nov 24. PMID: 11755008

Curcumin may have therapeutic value in colon cancer prevention.
Oncogene. 1999 Oct 28;18(44):6013-20. PMID: 10557090

Curcumin may have therapeutic value in patients prone to vascular thrombosis and requiring anti-arthritic therapy.
Arzneimittelforschung. 1986 Apr;36(4):715-7. PMID: 3521617

Curcumin may have therapeutic value in the prevention of cardiovascular complications associated with diabetes.
Nutr Metab (Lond). 2006;3:27. Epub 2006 Jul 18. PMID: 16848894

Curcumin may have therapeutic value in the treatment of hyperlipidemia.
J Med Food. 2005;8(2):256-60. PMID: 16117621

Curcumin may have therapeutic value in treating aortic stenosis, left ventricular dysfunction and myocardial fibrosis.
Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Mar;37(3):262-7. PMID: 19781154

Curcumin may have therapeutic value in treating scleroderma.
Am J Respir Cell Mol Biol. 2004 Jul;31(1):28-35. Epub 2004 Jan 23. PMID: 14742295

Curcumin may increase muscle tone in urinary bladder.
Evid Based Complement Alternat Med. 2008 Sep;5(3):281-7. PMID: 20172017

Curcumin may inhibit cardiac hypertrophy and myocardial infarction.
Lab Invest. 2009 Oct 19. PMID: 18292806

Curcumin may offer protective effects against methotrexate-induced rat enteritis by lowering the intestinal mucosal permeability.
Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jan;28(1):119-21. PMID: 18227041

Curcumin may play a role in preventing diabetes-induced cardiomyopathy.
Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1119-26. Epub 2008 Apr 15. PMID: 18413674

Curcumin may play a therapeutic role in treating depression.
Psychopharmacology (Berl). 2008 Dec;201(3):435-42. Epub 2008 Sep 3. PMID: 18766332

Curcumin may play its therapetuic role by leveling down the content of extracellular matrix in rats with pulmonary fibrosis induced by bleomycin.
Zhongguo Zhong Yao Za Zhi. 2006 Apr;31(7):570-3. PMID: 16780161

Curcumin may protect against sepsis.
Crit Care Med. 2006 Jul;34(7):1874-82. PMID: 16715036

Curcumin may protect the aging brain from oxidative stress.
Int J Dev Neurosci. 2010 Aug;28(5):351-7. Epub 2010 Apr 18. PMID: 20403421

Curcumin may provide an ideal lead molecule for the prevention and treatment of TTR amyloidosis.
Biochim Biophys Acta. 2012 Oct 13. Epub 2012 Oct 13. PMID: 23069388

Curcumin may provide an ideal therapeutic agent in the treatment of heart failure.
J Clin Invest. 2008 Mar;118(3):868-78. PMID: 18292809

Curcumin may reduce adverse effects associated with stress.
Domest Anim Endocrinol. 2010 Nov;39(4):231-9. Epub 2010 Jul 30. PMID: 20920780

Curcumin may reduce pain by activation of both opioid and non opioid mechanisms.
Pak J Biol Sci. 2007 Aug 1;10(15):2583-6. PMID: 19070135

Curcumin may stimulate recovery from spinal cord injury.
J Neurosurg Spine. 2012 Feb 10. Epub 2012 Feb 10. PMID: 22324804

Curcumin might be an effective antifibrotic drug in the treatment of chronic kidney disease.
Kidney Int. 2004 Jul;66(1):112-20. PMID: 15200418

Curcumin might increase the effect of vitamin C in protecting the function of endothelial cells..
Clin Hemorheol Microcirc. 2006;35(4):481-9. PMID: 17148847

Curcumin might significantly decrease the level of insulin resistance and leptin resistance caused by the high fat diet.
J Atheroscler Thromb. 2009;16(6):870-7. Epub 2009 Dec 22. PMID: 19176142

Curcumin modulates the immune response associated with LPS-induced periodontal disease in rats, indicating its potential therapeutic value.
Innate Immun. 2011 Jan 17. Epub 2011 Jan 17. PMID: 21242275

Curcumin oil has a protective effect against cisplatin-induced nephrotoxicity.
J Agric Food Chem. 2007 Dec 12;55(25):10150-5. Epub 2007 Nov 15. PMID: 18001039

Curcumin oil has anti-platelet effects in an experimental model of myocardial ischemia-reperfusion and thrombosis.
Thromb Res. 2011 Feb;127(2):111-8. Epub 2010 Dec 8. PMID: 21144557

Curcumin positively modulates leukocyte and platelet adhesion and improves survival in mouse sepsis.
Microcirculation. 2010 Aug;17(6):407-16. PMID: 20690979

Curcumin potentiates the activity of the chemotherapy agent gemcitabine in vitro and in vivo animal models of pancreatic cancer.
Cancer Res. 2007 Apr 15;67(8):3853-61. PMID: 17440100

Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer.
Cancer Res. 2009 Dec 1;69(23):8958-66. Epub 2009 Nov 10. PMID: 19903839

Curcumin potentiates the antitumor effects of gemcitabine in an animal model of human bladder cancer...
Biochem Pharmacol. 2010 Jan 15;79(2):218-28. Epub 2009 Aug 12. PMID: 19682434

Curcumin preserves pancreatic islet cell survival and transplantation efficiency.
Life Sci. 2008 Jan 16;82(3-4):182-9. Epub 2007 Nov 21. PMID: 18093618

Curcumin pretreatment has a beneficial effect on wound healing in mice whole-body exposed to various doses of gamma-radiation.
Chemosphere. 2009 Mar;74(9):1145-51. Epub 2009 Jan 13. PMID: 15172199

Curcumin pretreatment protects against acute acrylonitrile-induced oxidative damage in rats.
Radiat Oncol. 2010 Nov 22;5(1):111. Epub 2010 Nov 22. PMID: 19913070

Curcumin prevents adriamycin nephrotoxicity in rats.
Br J Pharmacol. 2000 Jan;129(2):231-4. PMID: 10694226

Curcumin prevents advanced glycation induced complications of diabetes.
Biochem Pharmacol. 1998 Dec 15;56(12):1607-14. PMID: 9973181

Curcumin prevents alcohol-induced liver disease in rats.
Am J Physiol Gastrointest Liver Physiol. 2003 Feb;284(2):G321-7. Epub 2002 Aug 28. PMID: 12388178

Curcumin prevents and reverses cirrhosis induced by bile duct obstruction.
Fundam Clin Pharmacol. 2008 Aug;22(4):417-27. PMID: 18705752

Curcumin prevents and/or delays diabetic complications associated with brain.
J Agric Food Chem. 2008 Nov 12;56(21):9905-10. Epub 2008 Oct 2. PMID: 20637830

Curcumin prevents cardiac remodeling secondary to chronic renal failure in rats.
Am J Physiol Heart Circ Physiol. 2010 Oct;299(4):H975-84. Epub 2010 Jul 2. PMID: 20601462

Curcumin prevents chemically-induced colitis in mice.
Gastroenterology. 2002 Dec;123(6):1912-22. PMID: 12454848

Curcumin prevents chemically-induced colitis.
Scand J Gastroenterol. 2009;44(2):187-94. PMID: 18830899

Curcumin prevents chemically-induced colitis.
World J Gastroenterol. 2005 Mar 28;11(12):1747-52. PMID: 15793857

Curcumin prevents chemically-induced liver cancer.
Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):439-42. Epub 2006 Dec 15. PMID: 10657978

Curcumin prevents chemically-induced liver cancer.
Cancer Lett. 2001 Jun 10;167(1):33-8. PMID: 11323096

Curcumin prevents chemically-induced lung and liver tumorigenesis.
In Vivo. 2008 Nov-Dec;22(6):781-5. PMID: 19181006

Curcumin prevents chemically-induced mammary cancer.
Cancer Lett. 1996 Jun 5;103(2):137-41. PMID: 8635149

Curcumin prevents chemically-induced skin cancer.
Adv Enzyme Regul. 1991;31:385-96. PMID: 1908616

Curcumin prevents cisplatin-induced chromosomal abberations in rat bone marrow cells.
Mutat Res. 2000 Feb 16;465(1-2):131-7. PMID: 10708978

Curcumin prevents colon carcinogenesis.
Carcinogenesis. 1999 Apr;20(4):641-4. PMID: 10223193

Curcumin prevents diabetes-associated abnormalities in the kidneys.
Nutrition. 2009 Sep;25(9):964-72. Epub 2009 Mar 5. PMID: 19268536

Curcumin prevents ethanol-induced brain damage.
Phytother Res. 1999 Nov;13(7):571-4. PMID: 10548748

Curcumin prevents experimentally induced epileptogenesis in rats.
Epilepsy Behav. 2009 Feb;14(2):300-8. Epub 2008 Dec 17. PMID: 19100339

Curcumin prevents forebrain ischemia-induced neuronal damage and oxidative insult in the rat hippocampus.
Neurochem Res. 2006 May;31(5):611-8. Epub 2006 May 23. PMID: 16770732

Curcumin prevents free radical-mediated cataractogenesis.
Free Radic Biol Med. 2010 Feb 15;48(4):483-92. Epub 2009 Dec 10. PMID: 19932168

Curcumin prevents fructose-induced hepatic steatosis driven by hepatic insulin and leptin resistance.
Hepatology. 2010 May;51(5):1555-66. PMID: 20222050

Curcumin prevents glandular stomach cancer in rats.
Anticancer Res. 2001 Sep-Oct;21(5):3407-11. PMID: 11848501

Curcumin prevents Haloperidol-induced adverse effects.
Pharmacol Biochem Behav. 2008 Feb;88(4):511-22. Epub 2007 Oct 25. PMID: 18022680

Curcumin prevents human aortic smooth muscle cells migration associated with the development atherosclerosis.
Nutr Metab Cardiovasc Dis. 2010 Feb;20(2):125-32. Epub 2009 May 17. PMID: 19447587

Curcumin prevents liver cancer metastasis in an animal model.
Oncology. 2003;65(3):250-8. PMID: 14657599

Curcumin prevents liver fibrosis.
J Nat Med. 2009 Oct;63(4):415-20. Epub 2009 Jun 25. PMID: 19554395

Curcumin prevents mesenteric ischemia-reperfusion injury in a rodent model.
Am J Physiol Heart Circ Physiol. 2006 Sep;291(3):H1329-36. Epub 2006 Apr 14. PMID: 19917353

Curcumin prevents myocardial ischemia in the cat heart.
Indian J Med Res. 1995 Jan;101:31-5. PMID: 7883281

Curcumin prevents ocular toxicity of naphthalene in rats.
Toxicol Lett. 2000 Jun 5;115(3):195-204. PMID: 10814889

Curcumin prevents oxidative kidney damage induced by acetaminophen in rats.
Food Chem Toxicol. 2009 Jul;47(7):1480-4. Epub 2009 Apr 2. PMID: 19345714

Curcumin prevents radiation-induced mammary tumors.
Int J Radiat Oncol Biol Phys. 2002 Jan 1;52(1):212-23. PMID: 11777641

Curcumin prevents radiation-induced thymic lymphoma in mice.
J Environ Pathol Toxicol Oncol. 2007;26(4):273-9. PMID: 18197825

Curcumin prevents restenosis in a rabbit artery stent model.
Catheter Cardiovasc Interv. 2009 Nov 15;74(6):881-8. PMID: 19496118

Curcumin prevents selenite-induced cataractogenesis in rat pups.
Curr Eye Res. 2010 Feb;35(2):122-9. PMID: 20136422

Curcumin prevents shock-wave lithotripsy-induced renal injury.
Urol Res. 2009 Jun;37(3):159-64. Epub 2009 Apr 2. PMID: 19340419

Curcumin prevents the development of chemically-induced precancerous colonic lesions in male obese mice.
Nutr Cancer. 2012 Jan ;64(1):72-9. Epub 2011 Dec 15. PMID: 22172229

Curcumin prevents the development of experimental colitis.
Dig Dis Sci. 2007 Nov;52(11):2993-8. Epub 2007 Apr 11. PMID: 17429738

Curcumin produces beneficial changes in bone turnover and increases in bone strength...
Phytomedicine. 2008 Dec;15(12):1069-78. Epub 2008 Aug 6. PMID: 18693096

Curcumin protects against paraquat pulmonary toxicity.
Life Sci. 2000;66(2):PL21-8. PMID: 10666014

Curcumin protects against acetaminophen-induced toxicity.
Curr Neurovasc Res. 2012 Jan 16. Epub 2012 Jan 16. PMID: 22272768

Curcumin protects against acute liver damage in the rat.
Biochim Biophys Acta. 2007 Jun;1770(6):989-96. Epub 2007 Feb 22. PMID: 17383825

Curcumin protects against aflatoxin-induced biochemical changes in testis of mice.
Fertil Steril. 2009 Feb;91(2):597-601. Epub 2008 Feb 21. PMID: 18291380

Curcumin protects against alcohol and oxidized fat-induced liver toxicity.
Ital J Biochem. 2004 Jul;53(2):61-6. PMID: 15646009

Curcumin protects against alcohol and PUFA-induced lipid peroxidation.
Phytother Res. 2003 Sep;17(8):925-9. PMID: 13680826

Curcumin protects against amiodarone-induced pulmonary fibrosis in rats.
Br J Pharmacol. 2003 Aug;139(7):1342-50. PMID: 12890714

Curcumin protects against atherosclerosis in a mouse model.
J Physiol Pharmacol. 2005 Dec;56(4):627-35. PMID: 16391419

Curcumin protects against bleomycin-induced damages in pulmonary functions in rats
Zhongguo Zhong Yao Za Zhi. 2008 Jun;33(12):1434-8. PMID: 18837350

Curcumin protects against chemically-induced colitis in the mouse model.
J Pharm Pharmacol. 2007 Jun;59(6):849-56. PMID: 19285535

Curcumin protects against chemically-induced liver damage in rats.
Life Sci. 2006 Apr 4;78(19):2188-93. Epub 2005 Nov 8. PMID: 16288784

Curcumin protects against chemically-induced neurotoxicity in mice.
Anticancer Res. 1998 Sep-Oct;18(5A):3487-91. PMID: 20054649

Curcumin protects against chemically-induced oxidative stress in the brain.
Eur Rev Med Pharmacol Sci. 2006 Jul-Aug;10(4):157-61. PMID: 16910344

Curcumin protects against chemically-induced rat liver injury.
Int J Cancer. 2005 Mar 20;114(2):190-4. PMID: 10813555

Curcumin protects against cigarette smoke and ethanol-induced lipid alterations in rat lung and liver.
J Appl Microbiol. 2009 Jun;106(6):2086-95. Epub 2009 Mar 9. PMID: 16691314

Curcumin protects against cisplatin-induced oxidative injury in rat testis.
Hum Reprod. 2009 Jul;24(7):1717-25. Epub 2009 Mar 11. PMID: 19279034

Curcumin protects against colchicine-induced cognitive dysfunction and oxidative stress in rats.
Hum Exp Toxicol. 2012 Jan 19. Epub 2012 Jan 19. PMID: 22262262

Curcumin protects against copper-induced genotoxicity.
Anticancer Res. 1998 Nov-Dec;18(6A):4083-90. PMID: 17998598

Curcumin protects against cyclophosphamide-induced haemorrhagic cystitis.
Biochem Biophys Res Commun. 2004 Apr 16;316(4):1065-72. PMID: 19413659

Curcumin protects against cypermethrin-induced oxidative stress in rats.
Exp Toxicol Pathol. 2010 Dec 2. Epub 2010 Dec 2. PMID: 21130633

Curcumin protects against d-galactose-induced senescence in mice.
J Asian Nat Prod Res. 2011 Jan;13(1):42-55. PMID: 21253949

Curcumin protects against doxorubicin (adriamycin)-induced toxicity in rats.
J Med Food. 2009 Apr;12(2):394-402. PMID: 19459743

Curcumin protects against encephalopathy in the animal model.
Mutat Res. 2008 Dec 8;657(2):105-10. Epub 2008 Aug 22. PMID: 19000058

Curcumin protects against endotoxin-induced acute liver injury in rats.
J Huazhong Univ Sci Technolog Med Sci. 2006;26(6):678-81. PMID: 17357487

Curcumin protects against experimental liver injury in mice.
Zhongguo Zhong Yao Za Zhi. 2003 Aug;28(8):756-8, 793. PMID: 15015361

Curcumin protects against familial adenomatous polyposis and decreases intestinal bleeding as compared to NSAID drugs.
Biol Pharm Bull. 2009 Mar;32(3):382-8. PMID: 12050094

Curcumin protects against gamma radiation-induced ileal mucosal damage.
Arch Toxicol. 2009 Jun;83(6):609-17. Epub 2008 Aug 27. PMID: 18754102

Curcumin protects against Haloperidol-associated neurotoxicity.
J Altern Complement Med. 2004 Dec;10(6):1015-8. PMID: 21076901

Curcumin protects against hemorrhage/resuscitation injury.
Shock. 2003 Feb;19(2):150-6. PMID: 12578124

Curcumin protects against hepatic and renal injury.
Microsc Res Tech. 2009 Dec 18. Epub 2009 Dec 18. PMID: 20025056

Curcumin protects against indomethacin-induced gastric injury.
Anticancer Drugs. 2009 Oct;20(9):757-69. PMID: 16631530

Curcumin protects against ischaemia/reperfusion insult in rat forebrain.
Pharmacol Res. 2002 Sep;46(3):273-9. PMID: 12220971

Curcumin protects against ischemia/reperfusion injury in rat kidneys.
World J Urol. 2008 Jun;26(3):285-91. Epub 2008 Mar 29. PMID: 18373094

Curcumin protects against isoproterenol induced myocardial infarction in rats.
Nutr Cancer. 2001;39(1):148-53. PMID: 8858558

Curcumin protects against lead neurotoxicity in rats.
Hum Exp Toxicol. 2003 Dec;22(12):653-8. PMID: 14992327

Curcumin protects against lipid peroxidation and oxidative stress during nicotine-induced toxicity.
Toxicol Mech Methods. 2004;14(6):339-43. PMID: 20021100

Curcumin protects against methionine-induced hyperlipidemia and hyperhomocysteinemia in rats.
Indian J Exp Biol. 2008 Jul;46(7):534-40. PMID: 18807758

Curcumin protects against myocardial oxidative damage induced by isoproterenol in rats.
Hum Exp Toxicol. 2007 Dec;26(12):933-8. PMID: 18375636

Curcumin protects against necrotizing enterocolitis in neonatal rats.
Zhongguo Dang Dai Er Ke Za Zhi. 2010 Feb;12(2):132-6. PMID: 20199731

Curcumin protects against nicotine-induced lung toxicity by modulating the extent of lipid peroxidation and augmenting antioxidant defense system.
Pol J Pharmacol. 2004 Sep-Oct;56(5):581-6. PMID: 15591646

Curcumin protects against oxidative and nitrative stress after praziquantel treatment in liver fluke-infected hamsters.
Int J Parasitol. 2011 Jan 21. Epub 2011 Jan 21. PMID: 21256849

Curcumin protects against oxidative insult induced by pentylenetetrazol in epileptic rats.
Methods Find Exp Clin Pharmacol. 2010 May;32(4):227-32. PMID: 20508869

Curcumin protects against seizures and cognitive impairment in a drug-induced epileptic rat model.
Life Sci. 2010 Sep 16. Epub 2010 Sep 16. PMID: 20840851

Curcumin protects against the anti-rejection drug cyclosporine-induced nephrotoxicity.
Gen Physiol Biophys. 2010 Mar;29(1):85-94. PMID: 20371885

Curcumin protects against the development of diabetic nephropathy, in a diabetic rat experimental model.
Br J Pharmacol. 2008 Mar;153(6):1225-31. Epub 2008 Jan 21. PMID: 18204486

Curcumin protects against vancomycin-induced kidney damage in rats.
Exp Toxicol Pathol. 2010 Sep 8. Epub 2010 Sep 8. PMID: 20832269

Curcumin protects bleomycin-induced lung injury in rats.
Pharm Res. 2008 Sep;25(9):2181-9. Epub 2008 Apr 25. PMID: 9250724

Curcumin protects intestinal mucosal barrier function of rat enteritis.
PLoS One. 2010;5(9):e12969. Epub 2010 Sep 24. PMID: 20885979

Curcumin protects pancreatic islet cells and chemically-induced type 1 diabetes.
Br J Pharmacol. 2008 Nov;155(5):702-13. Epub 2008 Aug 11. PMID: 18695642

Curcumin protects pre-oligodendrocytes from activated microglia...
Brain Res. 2010 Jun 21;1339:60-9. Epub 2010 Apr 24. PMID: 20403340

Curcumin protects rat brains against focal ischemia.
Brain Res. 2009 Jul 28;1282:133-41. Epub 2009 May 13. PMID: 19445907

Curcumin protects rat myocardium against isoproterenol-induced ischemic injury.
J Cardiovasc Pharmacol. 2010 Apr;55(4):377-84. PMID: 20125031

Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine.
Eur J Pharmacol. 2010 Feb 25;628(1-3):274-81. Epub 2009 Nov 15. PMID: 19919835

Curcumin protects retinal cells from light-and oxidant stress-induced cell death...
Free Radic Biol Med. 2009 Mar 1;46(5):672-9. Epub 2008 Dec 24. PMID: 19121385

Curcumin protects testicle cells of mice from damage induced by chronic alcohol administration.
Med Sci Monit. 2008 Nov;14(11):BR237-42. PMID: 18971866

Curcumin protects the liver against aflatoxin-induced changes.
Poult Sci. 2009 Dec;88(12):2620-7. PMID: 19903961

Curcumin protects the mmune system and body weight gain on rats intoxicated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD).
Immunopharmacol Immunotoxicol. 2010 Mar;32(1):99-104. PMID: 19821784

Curcumin protects the rat liver from chemically-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation.
Mol Pharmacol. 2008 Feb;73(2):399-409. Epub 2007 Nov 15. PMID: 18006644

Curcumin reduced the side effects of mitomycin C in the treatment of breast cancer.
Cancer Sci. 2009 Nov;100(11):2040-5. Epub 2009 Jul 23. PMID: 19703194

Curcumin reduces adjuvant-induced c-reactive protein and inflammation.
Immunopharmacol Immunotoxicol. 2003 May;25(2):213-24. PMID: 12784914

Curcumin reduces burn progression in rats.
Acad Emerg Med. 2007 Dec;14(12):1125-9. PMID: 18045885

Curcumin reduces gallstone formation and biliary cholesterol concentration in mice.
Indian J Med Res. 1992 Oct;96:288-91. PMID: 1459671

Curcumin reduces high blood sugar and vascular inflammation in an animal model of type 1 diabetes.
Antioxid Redox Signal. 2009 Feb;11(2):241-9. PMID: 18976114

Curcumin reduces indomethacin-induced damage in the rat small intestine.
Cancer Res. 2010 Nov 15;70(22):9218-23. Epub 2010 Oct 26. PMID: 17351913

Curcumin reduces injury progression in a rat comb burn model.
J Burn Care Res. 2011 Jan-Feb;32(1):135-42. PMID: 21088615

Curcumin reduces intestinal inflammation and polyps, indicating its potential value for preventing colon cancer.
J Interferon Cytokine Res. 2010 Oct 15. Epub 2010 Oct 15. PMID: 20950131

curcumin reduces markers of liver damage in rats treated with heated sunflower oil or ethanol.
Vet Ital. 2010 Jan-Mar;46(1):83-92. PMID: 20391370

Curcumin reduces nitric oxide formation and associated inflammation in the rat mammary gland.
J Exp Biol. 2009 Jan;212(Pt 2):163-8. PMID: 11020339

Curcumin reduces oxidative and nitrative DNA damage associated with fluke infection.
Mol Nutr Food Res. 2009 Oct;53(10):1316-28. PMID: 19753608

Curcumin reduces oxidative stress associated with exposure to an environmental pollutant.
Toxicol Ind Health. 2011 Jan 18. Epub 2011 Jan 18. PMID: 21245202

Curcumin reduces pathogenesis in hamster-opisthorchiasis.
Southeast Asian J Trop Med Public Health. 2009 Nov;40(6):1208-15. PMID: 20578454

Curcumin reduces periductal fibrosis in liver fluke-infected in hamsters.
Eur J Pharmacol. 2010 Jul 25;638(1-3):134-41. Epub 2010 Apr 24. PMID: 20420820

Curcumin reduces pertussis-induced infectious brain edema in rats.
Biopharm Drug Dispos. 2006 Dec;27(9):407-20. PMID: 14723822

Curcumin reduces pulmonary tumorigenesis in transgenic mice.
Mol Nutr Food Res. 2011 Jul ;55(7):1036-43. Epub 2011 May 2. PMID: 21538854

Curcumin reduces rat hepatic fibrosis.
Zhonghua Gan Zang Bing Za Zhi. 2007 Oct;15(10):753-7. PMID: 17963602

Curcumin reduces the accumulation of collagen IV and fibronectin in the glomeruli...
Clin Cancer Res. 2009 Feb 15;15(4):1123-5. PMID: 15339499

Curcumin reduces the adverse effects of hyperinsulinemia associated with type 2 diabetes
Clin Breast Cancer. 2010 Jun;10(3):224-9. PMID: 19841616

Curcumin regresses tumors as well as protects the host from tumor-induced immunosuppression and toxicity.
Cancer Detect Prev. 2005;29(5):470-8. Epub 2005 Sep 26. PMID: 16188398

Curcumin regulates the shift from Th1 to Th2 in trinitrobenzene sulphonic acid-induced chronic colitis.
Acta Pharmacol Sin. 2006 Aug;27(8):1071-7. PMID: 16867261

Curcumin retards the growth of intestinal polyps in a mouse model of familial adenomatous polyposis.
Eur J Cancer. 2006 Feb;42(3):415-21. Epub 2006 Jan 4. PMID: 16387490

Curcumin reverses amyloid pathology and associated neurotoxicity in a mouse model of Alzheimer disease.
J Neurochem. 2007 Aug;102(4):1095-104. Epub 2007 Apr 30. PMID: 17472706

Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress.
Neuropharmacology. 2009 Sep;57(4):463-71. Epub 2009 Jun 21. PMID: 19540859

Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts.
Cell Mol Immunol. 2010 Jul;7(4):306-15. Epub 2010 Mar 22. PMID: 20305684

Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation.
Clin Cancer Res. 2008 Apr 1;14(7):2128-36. PMID: 18381954

Curcumin showed significant nephroprotective effects against Sodium Fluoride induced toxicity upon kidneys.
Biol Trace Elem Res. 2012 Mar ;145(3):369-74. Epub 2011 Sep 7. PMID: 21901432

Curcumin significantly attenuates carotid artery neointima formation.
Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):85-90. Epub 2005 Oct 20. PMID: 16239599

Curcumin reduces gallstone formation and biliary cholesterol concentration in mice.
Indian J Med Res. 1992 Oct;96:288-91. PMID: 1459671

Curcumin reduces high blood sugar and vascular inflammation in an animal model of type 1 diabetes.
Antioxid Redox Signal. 2009 Feb;11(2):241-9. PMID: 18976114

Curcumin reduces indomethacin-induced damage in the rat small intestine.
Cancer Res. 2010 Nov 15;70(22):9218-23. Epub 2010 Oct 26. PMID: 17351913

Curcumin reduces injury progression in a rat comb burn model.
J Burn Care Res. 2011 Jan-Feb;32(1):135-42. PMID: 21088615

Curcumin reduces intestinal inflammation and polyps, indicating its potential value for preventing colon cancer.
J Interferon Cytokine Res. 2010 Oct 15. Epub 2010 Oct 15. PMID: 20950131

curcumin reduces markers of liver damage in rats treated with heated sunflower oil or ethanol.
Vet Ital. 2010 Jan-Mar;46(1):83-92. PMID: 20391370

Curcumin reduces nitric oxide formation and associated inflammation in the rat mammary gland.
J Exp Biol. 2009 Jan;212(Pt 2):163-8. PMID: 11020339

Curcumin reduces oxidative and nitrative DNA damage associated with fluke infection.
Mol Nutr Food Res. 2009 Oct;53(10):1316-28. PMID: 19753608

Curcumin reduces oxidative stress associated with exposure to an environmental pollutant.
Toxicol Ind Health. 2011 Jan 18. Epub 2011 Jan 18. PMID: 21245202

Curcumin reduces pathogenesis in hamster-opisthorchiasis.
Southeast Asian J Trop Med Public Health. 2009 Nov;40(6):1208-15. PMID: 20578454

Curcumin reduces periductal fibrosis in liver fluke-infected in hamsters.
Eur J Pharmacol. 2010 Jul 25;638(1-3):134-41. Epub 2010 Apr 24. PMID: 20420820

Curcumin reduces pertussis-induced infectious brain edema in rats.
Biopharm Drug Dispos. 2006 Dec;27(9):407-20. PMID: 14723822

Curcumin reduces pulmonary tumorigenesis in transgenic mice.
Mol Nutr Food Res. 2011 Jul ;55(7):1036-43. Epub 2011 May 2. PMID: 21538854

Curcumin reduces rat hepatic fibrosis.
Zhonghua Gan Zang Bing Za Zhi. 2007 Oct;15(10):753-7. PMID: 17963602

Curcumin reduces the accumulation of collagen IV and fibronectin in the glomeruli...
Clin Cancer Res. 2009 Feb 15;15(4):1123-5. PMID: 15339499

Curcumin reduces the adverse effects of hyperinsulinemia associated with type 2 diabetes
Clin Breast Cancer. 2010 Jun;10(3):224-9. PMID: 19841616

Curcumin regresses tumors as well as protects the host from tumor-induced immunosuppression and toxicity.
Cancer Detect Prev. 2005;29(5):470-8. Epub 2005 Sep 26. PMID: 16188398

Curcumin regulates the shift from Th1 to Th2 in trinitrobenzene sulphonic acid-induced chronic colitis.
Acta Pharmacol Sin. 2006 Aug;27(8):1071-7. PMID: 16867261

Curcumin retards the growth of intestinal polyps in a mouse model of familial adenomatous polyposis.
Eur J Cancer. 2006 Feb;42(3):415-21. Epub 2006 Jan 4. PMID: 16387490

Curcumin reverses amyloid pathology and associated neurotoxicity in a mouse model of Alzheimer disease.
J Neurochem. 2007 Aug;102(4):1095-104. Epub 2007 Apr 30. PMID: 17472706

Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress.
Neuropharmacology. 2009 Sep;57(4):463-71. Epub 2009 Jun 21. PMID: 19540859

Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts.
Cell Mol Immunol. 2010 Jul;7(4):306-15. Epub 2010 Mar 22. PMID: 20305684

Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation.
Clin Cancer Res. 2008 Apr 1;14(7):2128-36. PMID: 18381954

Curcumin showed significant nephroprotective effects against Sodium Fluoride induced toxicity upon kidneys.
Biol Trace Elem Res. 2012 Mar ;145(3):369-74. Epub 2011 Sep 7. PMID: 21901432

Curcumin significantly attenuates carotid artery neointima formation.
Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):85-90. Epub 2005 Oct 20. PMID: 16239599

Curcumin's induction of enzymes involved in the detoxification of the electrophilic products of lipid peroxidation may contribute to the anti-inflammatory and anti-cancer activities of curcumin.
Int J Biochem Cell Biol. 1998 Apr;30(4):445-56. PMID: 9675878

Curcumin's inhibition of intestinal tumors is associated with changes in the intestinal immune cell profile.
J Surg Res. 2000 Apr;89(2):169-75. PMID: 10729246

Curcumin's neuroprotective properties may be due to its anticholinesterase, antioxidant activity and brain insulin receptor modulating activities.
Pharmacol Res. 2010 Mar;61(3):247-52. Epub 2009 Dec 21. PMID: 20026275

Curcumin, a NF-kappaB inhibitor, stimulates muscle regeneration after traumatic injury.
Am J Physiol. 1999 Aug;277(2 Pt 1):C320-9. PMID: 10444409

Curcumin, beta-carontein and hesperidin prevent chemically-induced oral cancer.
Cancer Res. 1994 Sep 1;54(17):4653-9. PMID: 8062259

Curcumin, capsaicin and garlic attenuate adverse blood changes associated with a cholesterol-enriched diet.
Br J Nutr. 2005 Jan;93(1):81-91. PMID: 15705229

Curcumin, capsaicin and garlic have a beneficial influence on erythrocyte integrity in high-fat fed rats.
J Nutr Biochem. 2006 Jul;17(7):471-8. Epub 2005 Oct 25. PMID: 16263255

Curcumin, capsaicin and garlic inhibit adverse blood and liver changes associated wtih a high-fat diet in rats.
Ann Nutr Metab. 2004 Sep-Oct;48(5):314-20. Epub 2004 Oct 1. PMID: 15467281

Curcumin, capsaicin and garlic reduce adverse changes in red blood cells associated with hypercholesterolemia.
Mol Cell Biochem. 2002 Jul;236(1-2):155-61. PMID: 12190115

Curcumin, capsaicin, and garlic have a beneficial effect in the red blood cells and liver of cholesterol fed rats.
Acta Pharmacol Sin. 2007 Oct;28(10):1559-65. PMID: 15296079

Curcumin, ellagic acid and bixin attenuate radiation induced toxicity.
Indian J Exp Biol. 1996 Sep;34(9):845-7. PMID: 9014516

Curcumin, ellagic acid and bixin provide protection against chromosome damage produced by radiation.
J Exp Clin Cancer Res. 1998 Dec;17(4):431-4. PMID: 10089063

Curcumin, resveratrol and melatonin protect against cadmium-induced oxidative damage.
Toxicology. 2006 Aug 15;225(2-3):150-6. Epub 2006 May 26. PMID: 16806632

Curcumin, silymarin and N-acetylcysteine protect against antitubercular drug-induced hepatotoxicity.
Hum Exp Toxicol. 2012 Feb 8. Epub 2012 Feb 8. PMID: 22318308

Curcumin-free turmeric extract inhibits chemically-induced gastric tumors in mice.
Cancer Lett. 1997 Sep 16;118(1):79-85. PMID: 9310263

Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR human oral cancer cells.
Int J Oncol. 2013 Oct ;43(4):1141-50. Epub 2013 Aug 5. PMID: 23917396

Curcumin-manganese complexes have enhanced antioxidant activity.
Free Radic Biol Med. 2003 Dec 15;35(12):1632-44. PMID: 14680686

Curcuminoid supplementation ameliorates cardiac autonomic imbalance in high-fat-fed rats, probably due to its lipid-lowering effect.
Nutrition. 2009 Jul-Aug;25(7-8):870-8. Epub 2009 Apr 23. PMID: 19398300

Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease.
Neuroscience. 2010 Sep 1;169(3):1296-306. Epub 2010 Jun 9. PMID: 20538041

Curcuminoids exhibit anti-allergy activity.
Bioorg Med Chem. 2004 Nov 15;12(22):5891-8. PMID: 15498665

Curcuminoids exhibit anti-spasmodic activity in pig ileum and rat uterus.
CNS Drugs. 2007;21 Suppl 1:39-43; discussion 45-6. PMID: 12930003

Curcuminoids inhibit chemically-induced tumor promotion.
Carcinogenesis. 1995 Oct;16(10):2493-7. PMID: 7586157

Curcuminoids inhibit chemically-induced tumor promotion.
Carcinogenesis. 1995 Oct;16(10):2493-7. PMID: 7586157

Curcuminoids may suppress liver inflammation associated with endotoxemia.
Shock. 2002 May;17(5):399-403. PMID: 12022761

Curcuminoids positively modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain.
Free Radic Res. 2008 Nov;42(11-12):999-1005. PMID: 19031318

Curcuminoids, curcumin, and demethoxycurcumin reduce lead-induced memory deficits in male rats.
J Agric Food Chem. 2007 Feb 7;55(3):1039-44. PMID: 17263510

Curry feeding inhibits cancer in a cell-transplanted mouse model.
Asia Pac J Clin Nutr. 2007;16(1):30-9. PMID: 17215178

Curumin reduces inflammation associated with Angiostrongylus cantonensis-induced eosinophilic meningitis.
J Helminthol. 2007 Mar;81(1):1-5. PMID: 17381860

Dietary constituents inhibit chemically-induced DNA and hemoglobin adductions associated with cancer.
Appl Radiat Isot. 2003 Mar;58(3):291-8. PMID: 12595006

Dietary curcumin and capsaicin have hypolipidemic and antioxidant effects.
Life Sci. 2001 Dec 7;70(3):253-67. PMID: 17960446

Dietary curcumin attenuates glioma growth.
Clin Cancer Res. 2010 Dec 1;16(23):5781-95. PMID: 21138870

Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition.
Exp Neurol. 2006 Feb;197(2):309-17. Epub 2005 Dec 20. PMID: 16364299

Dietary curcumin has a chemopreventive effect on inflammation-induced colorectal carcinogenesis in mice.
Mol Nutr Food Res. 2011 Feb;55(2):259-67. Epub 2010 Sep 16. PMID: 20848615

Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice.
Radiat Res. 2010 May;173(5):590-601. PMID: 20426658

Dietary curcumin inhibits chemically induced gastric cancer in mice.
Carcinogenesis. 1998 Aug;19(8):1357-60. PMID: 9744529

Dietary curcumin inhibits forestomach, duodenal, and colon carcinogenesis in mice.
Cancer Res. 1994 Nov 15;54(22):5841-7. PMID: 7954412

Dietary curcumin prevents colon carcinogenesis.
Cancer Res. 1995 Jan 15;55(2):259-66. PMID: 7812955

Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity.
Endocrinology. 2008 Jul;149(7):3549-58. Epub 2008 Apr 10. PMID: 18403477

Dietary curcuminoids prevent high-fat diet-induced lipid accumulation in rat liver and epididymal adipose tissue.
J Nutr. 2001 Nov;131(11):2932-5. PMID: 11694621

Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in male mice, indicating its protective value against chemical carcinogenesis and toxicity.
Pharmacol Toxicol. 2003 Jan;92(1):33-8. PMID: 12710595

Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis.
Anticancer Res. 2013 Sep ;33(9):3603-9. PMID: 24023285

Embelin and curcumin have a beneficial effect against oxidative tissue damage during chemically-induced hepatocarinogenesis in rats.
Mol Cell Biochem. 2006 Mar;284(1-2):49-55. Epub 2006 Feb 14. PMID: 16477385

Embelin and curcumin have a chemopreventive effect against chemically-induced liver cancer.
Fitoterapia. 2005 Sep;76(6):549-55. PMID: 16009505

Fucoxanthin, lutein and tetrahydrocurcumin may have chemopreventive effects against colon carcinogenesis.
Carcinogenesis. 1998 Jan;19(1):81-5. PMID: 9472697

Garlic and turmeric restore endothelial function in rats.
Life Sci. 2005 Jul 8;77(8):837-57. Epub 2005 Apr 14. PMID: 15964306

Grape seed extract, black seed extract and curcumin ameliorate tamoxifen-induced liver injury.
Hepatogastroenterology. 2007 Jan-Feb;54(73):320-4. PMID: 21046982

Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease.
Mutat Res. 2009 Feb 10;661(1-2):25-34. Epub 2008 Nov 6. PMID: 19027755

Melatonin and curcumin protect against ndomethacin-induced acute gastric ulceration.
Free Radic Biol Med. 2006 Sep 15;41(6):911-25. Epub 2006 Apr 30. PMID: 16934674

Melatonin, curcumin, quercetin, and resveratrol ameliorate chemically-induced kidney damage.
Neuro Endocrinol Lett. 2007 Dec;28(6):739-44. PMID: 18684806

NAC and curcumin protect against malathion-induced toxicity in human peripheral blood mononuclear cells.
Toxicol In Vitro. 2009 Oct;23(7):1319-25. Epub 2009 Jul 14. PMID: 19607909

Nanocapsulated curcumin acts as an oral chemopreventive formulation against chemically-induced hepatocellular carcinoma in rat.
Chem Biol Interact. 2011 Dec 16. Epub 2011 Dec 16. PMID: 22197969

Nitric oxide modulation is involved in the protective effect of curcumin in ameliorating sleep deprivation-induced behavioral alterations and oxidative damage.
IEEE Trans Biomed Eng. 1997 Oct;44(10):909-20. PMID: 18586477

Nutritional antioxidants such as green tea polyphenols and tetrahydrocurcumin may beneficially modify the life span of animals.
Biogerontology. 2007 Oct;8(5):567-73. Epub 2007 May 22. PMID: 17516143

Omega-3 fatty acids, black seed oil and curcuminoids have a therapeutic role in gastritits in an animal model.
Eur J Nutr. 2007 Oct;46(7):391-6. Epub 2007 Sep 20. PMID: 18368490

Oral administration of curcumin reduces intestinal inflammation in a mouse model of irritable bowel syndrome.
Dig Dis Sci. 2010 May;55(5):1272-7. Epub 2009 Jun 10. PMID: 19513843

Oral curcumin inhibits skin carcinogenesis in mice.
Cancer Lett. 1997 Jun 24;116(2):197-203. PMID: 9215864

Oral curcumin may have chemopreventive properties against colorectal cancer.
Cancer Res. 2001 Feb 1;61(3):1058-64. PMID: 11221833

Oral curcumin may have therapeutic activity in treating inherited peripheral neuropathies.
Am J Hum Genet. 2007 Sep;81(3):438-53. Epub 2007 Aug 3. PMID: 17701891

Oral curcumin protects against chemically-induced skin cancer in mice.
BMC Cancer. 2001;1:1. Epub 2001 Jan 17. PMID: 11231886

Piperine and Curcumin (from Turmeric) attenuates Cadmium induced immunotoxicity.
Biometals. 2008 Dec;21(6):649-61. Epub 2008 Jun 20. PMID: 18566892

Pre-treatment with curcumin enhances oral bioavailability of docetaxel in rats.
Int J Pharm. 2010 Oct 31;399(1-2):116-20. Epub 2010 Aug 18. PMID: 20727390

Pretreatment of curcumin attenuates coagulopathy and renal injury in LPS-induced endotoxemia.
J Endotoxin Res. 2007;13(1):15-23. PMID: 17621542

Pretreatment with NAC and curcumin inhibit staphylococcal enteroxin A-induced fever in rabbits.
Mol Cell Biochem. 2004 Jul;262(1-2):177-85. PMID: 15532722

Quercetin and curcumin inhibit ischemic kidney injury.
Transplantation. 1998 Jul 27;66(2):147-52. PMID: 9701255

Quercetin and curcumin protect against paracetamol-induced histological changes, oxidative stress, impaired liver and kidney functions and haematotoxicity in rat.
Food Chem Toxicol. 2010 Nov;48(11):3246-61. Epub 2010 Sep 4. PMID: 20804811

Quercetin, curcumin, ginseng and rutin exhibit anti-cancer activity in an animal model of colon cancer.
Arch Neurol. 2003 Feb;60(2):194-200. PMID: 15831530

Red sage and curcumin exhibit anti-liver fibrotic properties.
Chin J Integr Med. 2006 Sep;12(3):207-11. PMID: 17005083

Resveratrol and curcumin may combine with insulin in attenuating diabetic neuropathic pain.
Phytother Res. 2007 Mar;21(3):278-83. PMID: 17199240

Resveratrol and curcumin reduce inflammation associated with acute small intestinal inflammation.
PLoS One. 2010;5(12):e15099. Epub 2010 Dec 3. PMID: 21151942

Safety Study: Curcumin may not be safe during pregnancy.
Int J Mol Sci. 2010;11(8):2839-55. Epub 2010 Aug 2. PMID: 21152277

Saffron, garlic and curcumin protect against yclophosphamide induced genotoxicity in mice.
Asia Pac J Clin Nutr. 2004;13(3):292-4. PMID: 15331343

Sulforaphane and curcumin protect against malathion toxicity.
Eur Rev Med Pharmacol Sci. 2012 Jul ;16 Suppl 3:144-8. PMID: 22957429

Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.
Mol Cancer Ther. 2010 Aug;9(8):2255-64. Epub 2010 Jul 20. PMID: 20647339

Tea and curcumin inhibit chemically-induced oral cancer.
Carcinogenesis. 2002 Aug;23(8):1307-13. PMID: 12151348

Tea and curcumin inhibit chemically-induced oral cancer.
Prog Neuropsychopharmacol Biol Psychiatry. 1994 Sep;18(5):915-24. PMID: 12572355

Tetrahydrocurcumin and rutin have cardioprotective properties in a rat model of myocardial infarction
Pharmazie. 2009 Feb;64(2):132-6. PMID: 19320287

Tetrahydrocurcumin displays antihyperlipidaemic effect in addition to its antidiabetic effect in type 2 diabetic rats.
Basic Clin Pharmacol Toxicol. 2006 Aug;99(2):122-7. PMID: 16918712

Tetrahydrocurcumin has a lipid lowering effects in a rat model of diabetes.
Chem Biol Interact. 2010 Dec 5;188(3):643-50. Epub 2010 Aug 7. PMID: 20696151

Tetrahydrocurcumin has a protective effect on hepatic and renal functional markers and protein levels in experimental type 2 diabetic rats.
Basic Clin Pharmacol Toxicol. 2007 Oct;101(4):241-5. PMID: 17845505

Tetrahydrocurcumin has antioxidant and anti-diabetic activity in streptozotocin-nicotinamide induced diabetic rats.
Life Sci. 2006 Sep 27;79(18):1720-8. Epub 2006 Jun 9. PMID: 16806281

Tetrahydrocurcumin increases the number of total cellular insulin binding sites resulting in a significant increase in plasma insulin.
J Biosci. 2008 Mar;33(1):63-72. PMID: 18376071

Tetrahydrocurcumin normalizes blood glucose and causes a marked improvement of altered carbohydrate metabolic enzymes in diabetic animals.
J Basic Clin Physiol Pharmacol. 2005;16(4):257-74. PMID: 16438392

Tetrahydrocurcumin prevents brain lipid peroxidation in streptozotocin-induced diabetic rats.
J Med Food. 2007 Jun;10(2):323-9. PMID: 17651069

Tetrahydrocurcumin protect against chloroquine induced liver toxicity.
J Pharm Pharm Sci. 2005;8(1):115-23. Epub 2005 Apr 30. PMID: 15946605

Tetrahydrocurcumin protects against oxidative damage associated with chemical exposure.
Basic Clin Pharmacol Toxicol. 2006 Nov;99(5):329-34. PMID: 17076682

Tetrahydrocurcumin protects against oxidative stress in cholesterol-fed rabbits.
J Atheroscler Thromb. 2002;9(5):243-50. PMID: 12409634

Tetrahydrocurcumin protectsagainst erythromycin estolate-induced lipid peroxidation in rats.
J Basic Clin Physiol Pharmacol. 2005;16(1):1-15. PMID: 16187483

Tetrahydrocurcumin protectsagainst erythromycin estolate-induced lipid peroxidation in rats.
J Basic Clin Physiol Pharmacol. 2005;16(1):1-15. PMID: 16187483

The combination of epigallocatechin gallate and curcumin suppresses ER alpha-breast cancer cell growth in vitro and in vivo.
Int J Cancer. 2008 May 1;122(9):1966-71. PMID: 18098290

The curry spice curcumin selectively inhibits cancer cells growth in vitro and in preclinical model of glioblastoma.
J Nutr Biochem. 2011 Jul 18. Epub 2011 Jul 18. PMID: 21775121

Topical curcumin attenuates photoaging in mice.
Rejuvenation Res. 2010 Apr 28. Epub 2010 Apr 28. PMID: 20426620

Tumeric and curcumin may prevent or delay the development of cataract.
Nutr J. 2008;7:3. Epub 2008 Jan 21. PMID: 15914628

Tumeric oil ameliorates the neurological functional deficits and infarct and edema volumes in the rat model of embolic stroke.
BMC Complement Altern Med. 2008 Sep 30;8:55. PMID: 18826584

Turmeric (Curcuma wenyujin) induces programmed cell death and inhibits proliferation in human cervical cancer cells in vitro and in vivo.
Integr Cancer Ther. 2010 Feb 11. Epub 2010 Feb 11. PMID: 20150221

Turmeric and catechin are effective chemopreventive agent.
J Ethnopharmacol. 1994 Dec;44(3):211-7. PMID: 7898128

Turmeric and curcumin appear to be beneficial in preventing diabetes-induced oxidative stress in rats.
Med Sci Monit. 2007 Dec;13(12):BR286-92. PMID: 18049430

Turmeric and curcumin have anti-diabetic actions.
Plant Foods Hum Nutr. 2002;57(1):41-52. PMID: 11855620

Turmeric and curcumin prevent benzo[a]pyrene-induced DNA adduct formation.
Carcinogenesis. 1993 Mar;14(3):493-6. PMID: 8453726

Turmeric and curcumin reverse aflatoxin-induced liver damage.
J Nutr Sci Vitaminol (Tokyo). 1992 Aug;38(4):353-63. PMID: 1291640

Turmeric and myrrh protect against liver oxidative damage and genotoxicity induced by lead acetate in mice.
Basic Clin Pharmacol Toxicol. 2006 Jan;98(1):32-7. PMID: 16433888

Turmeric extract and curcumin reduce the development of animal tumors.
Cancer Lett. 1985 Nov;29(2):197-202. PMID: 4075289

Turmeric extract and vitamin E have radioprotective properties in mice exposed to therapeutic radioiodine.
Indian J Clin Biochem. 2008 Oct ;23(4):382-6. Epub 2008 Dec 20. PMID: 23105792

Turmeric extract exhibits anti-Alzheimer properties.
Curr Alzheimer Res. 2011 Aug 30. Epub 2011 Aug 30. PMID: 21875408

Turmeric extract has a radioprotective effect on gamma-irradiation-induced oxidative stress in rats.
Can J Physiol Pharmacol. 2012 Mar 20. Epub 2012 Mar 20. PMID: 22432737

Turmeric extract protects against carcinogen and benzo[a]phyrene-induced mutagenicity, genotoxicity and carcinogenicity.
J Cancer Res Clin Oncol. 1992;118(6):447-52. PMID: 1618892

Turmeric has antispasmodic properties.
PLoS One. 2012 ;7(9):e44650. Epub 2012 Sep 12. PMID: 22984538

Turmeric has chemopreventive properties in a rat model of chemically-induced liver cancer.
Acta Histochem. 2011 Aug 25. Epub 2011 Aug 25. PMID: 21871653

Turmeric has significant blood-sugar lowering activity in type 2 diabetic mice.
Biol Pharm Bull. 2005 May;28(5):937-9. PMID: 15863912

Turmeric inhibits Epstein-Barr virus.
Clin Drug Investig. 2008;28(8):495-500. PMID: 11884218

Turmeric inhibits LDL oxidation and cholesterol lowering effects in rabbits with experimental atherosclerosis.
Atherosclerosis. 1999 Dec;147(2):371-8. PMID: 10559523

Turmeric is as efficacious has honey in speeding wound healing in rabbits.
Int J Low Extrem Wounds. 2005 Dec;4(4):205-13. PMID: 16286372

Turmeric is efficacious in an animal model of rheumatoid arthritis.
Arthritis Rheum. 2006 Nov;54(11):3452-64. PMID: 17075840

Turmeric is efficacious in preventing joint inflammation in an experimental model of rheumatoid arthritis.
J Nat Prod. 2006 Mar;69(3):351-5. PMID: 16562833

Turmeric is hypotensive and has vasodilating and bradycardic effects.
J Ethnopharmacol. 2009 May 27. PMID: 19481144

Turmeric may decrease the risk of atherosclerosis.
J Ethnopharmacol. 2002 Aug;81(3):357-64. PMID: 11593527

Turmeric oil (rhizoma curcumae oil) amplifies the effectiveness of Tamoxifen in a rat model of endometriosis.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2006 Jul;37(4):596-8. PMID: 16909610

Turmeric oil has a neuroprotective property in transient focal ischemia in rat brain.
Neurochem Res. 2008 Sep;33(9):1672-82. Epub 2007 Oct 23. PMID: 17955367

Turmeric powder combined with milk as therapeutic properties in an animdal model of both type 1 and type 2 diabetes.
Indian J Clin Biochem. 2010 Apr ;25(2):175-81. Epub 2010 May 27. PMID: 23105906

Turmeric prevents benzene-induced hematoxicity.
Zhonghua Yi Xue Za Zhi. 2009 Sep 15;89(34):2429-31. PMID: 20137700

Turmeric prevents benzo(a)pyrene-induced adverse changes in mice.
J Environ Pathol Toxicol Oncol. 2001;20(1):59-63. PMID: 11215708

Turmeric prevents chemically-induced skin and stomach cancer in mice.
Nutr Cancer. 1992;17(1):77-83. PMID: 1574446

Turmeric protects against iron-induced lipid peroxidation in the rat liver.
Food Chem Toxicol. 1994 Mar;32(3):279-83. PMID: 8157223

Turmeric reduces oxidative stress and attenuates aortic fatty streak development in rabbits.
Arterioscler Thromb Vasc Biol. 2002 Jul 1;22(7):1225-31. PMID: 12117742

Turmeric, garlic, curcumin and ellagic acid protect against aflatoxin-induced mutagenicity and hepatocarcinogenicity.
Cancer Lett. 1997 May 19;115(2):129-33. PMID: 9149115

Turmeric-based diet may provide protection against fibrosis and apoptosis elicited unilateral ureteral obstruction (UUO).
J Pharm Pharmacol. 2008 Jan;60(1):83-9. PMID: 18088509

Various plant phenols inhibit benzo[a]pyrene-induced nuclear a.berrations in mammalian intestinal cells
Food Chem Toxicol. 1985 Jan;23(1):47-9. PMID: 4038681

Various plant polyphenols inhibit lung cancer caused by metastatic melanoma.
Int Urol Nephrol. 2009 Jul 16. PMID: 7656234

Very low dose curcumin is effective against galactose-induced cataracts in rats.
Mol Vis. 2003 Jun 9;9:223-30. PMID: 12802258

Vitamin E and curcumin may alleviate the hepatic antioxidant gene expression in hyperthyroid rats.
Chem Biol Interact. 2010 Jan 27;183(2):304-16. Epub 2009 Nov 13. PMID: 19914224

Vitamin E and curcumin protects hypothyroid-induced altered rectal temperature, serum transaminase activity and hepatic histoarchitecture.
Life Sci. 2009 Mar 13;84(11-12):372-9. Epub 2009 Jan 13. PMID: 19174171

Vitamin E, turmeric and holy basil has significant radioprotective effects against Radioiodine-131 exposure in mice.
Indian J Exp Biol. 2010 Jun;48(6):566-71. PMID: 20882758

"Curcumin and Liver Cancer: A Review."
Curr Pharm Biotechnol. 2011 Apr 5. Epub 2011 Apr 5. PMID: 21466422

"Curcumin enhances the anticancer effects of trichostatin a in breast cancer cells."
Mol Carcinog. 2012 Jan 30. Epub 2012 Jan 30. PMID: 22290509

"Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9."
Molecules. 2013 ;18(1):701-20. Epub 2013 Jan 8. PMID: 23299550

"Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2."
Carcinogenesis. 2012 Dec ;33(12):2507-19. Epub 2012 Oct 5. PMID: 23042094

"Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhance its antioxidant and antihepatoma activities."
J Agric Food Chem. 2010 Jun 23 ;58(12):7376-82. PMID: 20486686

"Curcumin protects against intracellular amyloid toxicity in rat primary neurons."
Int J Clin Exp Med. 2012 ;5(1):44-9. Epub 2012 Jan 15. PMID: 22328947

"Curcumin targets fibroblast-tumor cell interactions in oral squamous cell carcinoma."
Exp Cell Res. 2012 Dec 13. Epub 2012 Dec 13. PMID: 23247073

"Curcumin: A Potential Neuroprotective Agent in Parkinson's Disease."
Curr Pharm Des. 2012 Jan 1. Epub 2012 Jan 1. PMID: 22211691

"Turmerin, the antioxidant protein from turmeric (Curcuma longa) exhibits antihyperglycaemic effects."
Nat Prod Res. 2011 Oct 6. Epub 2011 Oct 6. PMID: 21972920

A broad spectrum extract of turmeric (Turmeric Force) potentiates the anticancer activity of gemcitabine in pancreatic cancer cell lines.
Oncol Rep. 2010 Jun;23(6):1529-35. PMID: 20428806

A curcumin derivative inhibits the cell cycle progression of colon cancer cells
Chem Biol. 2004 Oct;11(10):1455-63. PMID: 15489172

A curcumin metabolite protects against Alzheimer disease associated amyloidß-induced toxicity.
Neuroreport. 2010 Nov 24. Epub 2010 Nov 24. PMID: 21116204

A curcumin-related compound has anti-tumor activity against against melanoma and neuroblastoma cells.
Mol Cancer. 2010;9:137. Epub 2010 Jun 3. PMID: 20525240

A multi-herbal product called Protandim attenuates intima hyperplasia.
Free Radic Biol Med. 2011 Mar 15;50(6):700-9. Epub 2010 Dec 15. PMID: 21167278

A multi-herbal product called Protandim has antioxidant properties.
Free Radic Biol Med. 2009 Feb 1;46(3):430-40. Epub 2008 Nov 17. PMID: 19056485

A novel demethylated curcuminoid exhibits neuroprotective and anti-inflammatory properties.
Antioxid Redox Signal. 2009 Mar;11(3):449-68. PMID: 18724833

A number of plant polyphenols have chemosensitizing and radiosensitizing activity.
Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1630-47. PMID: 16356126

A variety of natural compounds may inhibit cancer stem cells.
J Nutr Biochem. 2011 Sep ;22(9):799-806. Epub 2011 Feb 4. PMID: 21295962

A variety of natural substances have preventive potential in osteoarthritis and rheumatoid arthritis.
Arthritis Res Ther. 2011 Feb 3;13(1):102. Epub 2011 Feb 3. PMID: 21345249

A variety of natural substances may function as novel anticancer agents, proteasome inhibitors and chemosensitizers.
Drug Resist Updat. 2006 Dec;9(6):263-73. Epub 2007 Jan 2. PMID: 17197231

Antioxidant therapies for traumatic brain injury.
Neurotherapeutics. 2010 Jan;7(1):51-61. PMID: 20129497

Antioxidant therapy may be an effective treatment in COPD.
Int J Chron Obstruct Pulmon Dis. 2006;1(1):15-29. PMID: 18046899

Apigenin and curcumin effectively inhibit rhabdoid tumor cell growth.
Lipids Health Dis. 2004 Nov 9;3:24. PMID: 20147838

Apple and curcumin extracts contain phytochemicals which inhibit cellular processes associated with breast cancer cell resistance to chemotherapy.
J Agric Food Chem. 2007 Apr 18;55(8):3167-73. Epub 2007 Mar 21. PMID: 17373813

Ar-turmerone, a compound within turmeric, induces programmed cell death in two human cancer lines.
J Pharm Pharmacol. 1998 Sep;50(9):1065-8. PMID: 11956652

Ar-turmerone, a compound within turmeric, induces programmed cell death in various cancer cell lines.
Int J Mol Med. 2004 Aug;14(2):253-6.  


Curcumin (from Turmeric) protects against cardiac hypertrophy.
J Clin Invest. 2008 Mar;118(3):879-93. PMID: 18292803
 
Curcumin (in low doses) is protective against ethanol-induced liver damage.
Naunyn Schmiedebergs Arch Pharmacol. 2009 Jan;379(1):47-60. Epub 2008 Aug 21. PMID: 18716759

Curcumin abolished the resistance of human promyelocytic leukemia cells to programmed cell death.
FEBS Lett. 2006 Aug 21;580(19):4653-60. Epub 2006 Jul 21. PMID: 16876793

Curcumin activates defensive genes and protects neurons against oxidative stress.
Antioxid Redox Signal. 2006 Mar-Apr;8(3-4):395-403. PMID: 16677086

Curcumin acts as a chemosensitizing agent in lung cancer cells.
Biochem Biophys Res Commun. 2005 Jun 17;331(4):1245-52. PMID: 15883009

Curcumin acts on adipocytes to suppress the lipolysis response to TNFa and catecholamines
Phytomedicine. 2012 Oct 16. Epub 2012 Oct 16. PMID: 23083815

Curcumin acts on localized prostate cancer to induce programmed cell death.
Int Braz J Urol. 2009 May-Jun;35(3):354-60; discussion 361. PMID: 19538771

Curcumin acts synergistically with the chemotherapeutic agent bortexomib in treating multiple myeloma cells.
Mol Oncol. 2008 Dec;2(4):317-26. Epub 2008 Oct 7. PMID: 19383353

Curcumin and ascorbic acid exhibit antioxidant and anticarc
Cancer Lett. 1992 Apr 30;63(3):237-41. PMID: 1576592

Curcumin and beta-lapachone inhibit HIV virus replication.
Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1839-42. PMID: 8446597

Curcumin and betulinic acid downregulate epidermal growth factor receptor in bladder cancer cells.
Mol Cancer Res. 2010 May;8(5):739-50. Epub 2010 Apr 20. PMID: 20407012

Curcumin and catechin exhibit anti-metastatic activity in melanoma cells against lung metastasis.
Cancer Lett. 1999 Jul 1;141(1-2):159-65. PMID: 10454257

Curcumin and catechin works synergistically to inhibit rat colon carcinogensis.
Di Yi Jun Yi Da Xue Xue Bao. 2005 Jan;25(1):48-52. PMID: 15683997

Curcumin and chlorhexidine gluconate mouthwashes have comparable anti-plaque, anti-inflammatory and anti-microbial propert
J Indian Soc Periodontol. 2012 Jul ;16(3):386-91. PMID: 23162334

Curcumin and curcumin-boron complexes exhibit anti-HIV activity.
Bioorg Med Chem. 1993 Dec;1(6):415-22. PMID: 8087563

Curcumin and curcuminoids are neuroprotective in a variety of preclinical stroke models.
Respir Med. 2008 Jun;102(6):840-4. Epub 2008 Mar 4. PMID: 21158690

Curcumin and eugenol prevents lipid peroxidation of rat liver microsomes.
Mol Cell Biochem. 1992 Apr;111(1-2):117-24. PMID: 1588934

Curcumin and gallic acid are cytotoxic to leukemia and oral cancer cells.
Anticancer Res. 1998 Sep-Oct;18(5A):3487-91. PMID: 9858929

Curcumin and genistein induce programmed cell death in cervical cancer cell lines.
Folia Biol (Praha). 2010;56(5):195-200. PMID: 21138650

Curcumin and genistein may positively modulate EGF and therefore playing a therapeutic role in periodontal disease.
J Periodontal Res. 2004 Dec;39(6):380-7. PMID: 15491342

Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides.
Biochem Biophys Res Commun. 1997 Apr 28;233(3):692-6. PMID: 9168916

Curcumin and glutamine may have a therapeutic role in treating intestinal permeability.
Clinics (Sao Paulo). 2010 Jun;65(6):635-43. PMID: 20613941

Curcumin and NAC decrease alcohol toxicity associated changes in prostaglandin levels.
Biochem Pharmacol. 2000 Dec 1;60(11):1665-76. PMID: 11077049

Curcumin and NAC protect against pesticide-induced cell death in human peripheral blood mononuclear cells.
J Biochem Mol Toxicol. 2010 Sep;24(5):286-92. PMID: 20979154

Curcumin and nicotinamide inhibit radiation-induced nitration in mouse macrophages.
Mol Cell Biochem. 2005 Aug;276(1-2):7-13. PMID: 16132679

Curcumin and quercetin inhibit inflammatory processes associated with arthritis.
Inflamm Res. 2006 Apr;55(4):168-75. PMID: 16807698

Curcumin and resveratrol compare favorably with NSAID agents in inhibiting inflammatory processes associated with tumor cell proliferation.
Oncogene. 2004 Dec 9;23(57):9247-58. PMID: 15489888

Curcumin and resveratrol have a synergistic chondroprotective effect in human articular chondrocytes.
Arthritis Res Ther. 2009 Nov 4;11(6):R165. PMID: 19889203

Curcumin and resveratrol may attenuate dioxin toxicity.
Fukuoka Igaku Zasshi. 2005 May;96(5):204-13. PMID: 15997774

Curcumin and resveratrol may have chemopreventive properties in colorectal cancer.
Nutr Cancer. 2010 Oct;62(7):958-67. PMID: 20924971

Curcumin and resveratrol may inhibit the chronic inflammatory properties of adipose tissue.
Nutr Metab (Lond). 2008;5:17. Epub 2008 Jun 12. PMID: 18549505

Curcumin and resveratrol programmed cell death in human neuroblastoma.
Anticancer Res. 2004 Mar-Apr;24(2B):987-98. PMID: 15161054

Curcumin and soy isoflavones may work synergistically to prevent and treat pancreatic cancer.
Life Sci. 2008 Aug 15;83(7-8):293-300. Epub 2008 Jun 28. PMID: 18640131

Curcumin and tannic acid protect against glutamate-induced excitotoxicity.
J Pharmacol Exp Ther. 2006 Aug;318(2):476-83. Epub 2006 Apr 27. PMID: 17118359

Curcumin and turmeric attenuate arsenic-induced angiogenesis in ovo.
Altern Ther Health Med. 2010 Mar-Apr;16(2):12-4. PMID: 20232614
 
Curcumin and turmeric inhibit adverse consequences of lipid peroxidation.
J Ethnopharmacol. 2007 Mar 21;110(2):368-73. Epub 2006 Oct 13. PMID: 17116380

Curcumin antagonizes crucial catabolic effects of IL-1beta signaling that are known to contribute to the pathogenesis of osteoarthritis.
Ann N Y Acad Sci. 2004 Dec;1030:578-86. PMID: 15659840

Curcumin appears to be a safe and useful immunomodulator for the immune system.
Int Immunopharmacol. 2008 May;8(5):688-700. Epub 2008 Feb 13. PMID: 18387511

Curcumin appears to have therapeutic value in endothelial dysfunction.
Pharmacology. 2010;85(1):18-26. Epub 2009 Dec 1. PMID: 19955845

Curcumin appears to have value in multi-drug chemoresistance.
J Clin Rheumatol. 2010 Feb 2. Epub 2010 Feb 2. PMID: 14680379

Curcumin attenuates cisplatin induced mitochondrial dysfunction.
Food Chem Toxicol. 2012 Dec 11. Epub 2012 Dec 11. PMID: 23246825

Curcumin attenuates ethanol-induced stress on mononuclear cells.
Phytother Res. 2002 Mar;16(2):171-3. PMID: 11933122

Curcumin attenuates ethanol-induced toxicity in hippocampal cells.
Neurosci Lett. 2009 Apr 10;453(3):186-9. Epub 2009 Feb 20. PMID: 19429032

Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia.
Acta Pharmacol Sin. 2007 Oct;28(10):1645-51. PMID: 17883952

Curcumin augments gemcitabine cytotoxic effect on pancreatic cancer cell lines.
Cancer Invest. 2007 Sep;25(6):411-8. PMID: 17882652

Curcumin bioconjugates may make suitable antiviral agents.
Nucleic Acids Symp Ser (Oxf). 2008(52):599-600. PMID: 18776522

Curcumin blocks RON tyrosine kinase-mediated invasion of breast carcinoma cells.
Cancer Res. 2008 Jul 1;68(13):5185-92. PMID: 18593918

Curcumin blocks the activation of pancreatic stellate cells associated with inflammation and fibrosis.
J Cell Biochem. 2006 Apr 1;97(5):1080-93. PMID: 16294327

Curcumin blocks the invasiveness of prostate cancer cells.
Int J Oncol. 2009 May;34(5):1319-27. PMID: 19360344

Curcumin bound to phosphatidylcholine is superior to plain curcumin in combatting mammary gland tumor cell proliferation.
In Vivo. 2010 Jul-Aug;24(4):401-8. PMID: 20668306

Curcumin can be considered as a potential chemopreventive candidate against H. pylori-related gastric carcinogenesis.
Toxicol In Vitro. 2010 Mar;24(2):460-4. Epub 2009 Oct 13. PMID: 19889077

Curcumin can increase adiponectin secretion and decrease IL-6 secretion in human adipose tissues cultivated in vitro.
JPEN J Parenter Enteral Nutr. 2006 Jan-Feb;30(1):10-5. PMID: 18601853

Curcumin can induce global DNA hypomethylation in a leukemia cell line.
J Nutr. 2010 Jan;140(1):12-7. Epub 2009 Nov 18. PMID: 19112019

Curcumin can inhibit the growth and programmed cell death in acute promyelocytic leukemia (APL) cells.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Apr;18(2):340-3. PMID: 20416164

Curcumin can inhibit the proliferation and induce programmed cell death in melanoma cells.
Di Yi Jun Yi Da Xue Xue Bao. 2005 Dec;25(12):1517-21. PMID: 16361152

Curcumin can reverse the multi-drug resistance of a human gastric carcinoma cell line.
Acta Pharmacol Sin. 2005 Aug;26(8):1009-16. PMID: 16038636

Curcumin can suppress the growth of prostate cancer cells.
Zhonghua Nan Ke Xue. 2008 Feb;14(2):116-21. PMID: 18390174

Curcumin can suppress the invasion and migration of tongue cancer cells.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2008 Feb;43(2):101-4. PMID: 18683733

Curcumin causes cell cycle arrest and programmed cell death in human pancreatic cancer cells.
Br J Cancer. 2009 May 5;100(9):1425-33. PMID: 19401701

Curcumin chemosensitizes prostate cancer cells to TRAIL-induce programmed cell death.
J Exp Ther Oncol. 2005;5(2):81-91. PMID: 16471035

Curcumin compares favorably with oxaliplatin as an antiproliferative in colorectal cell lines.
Int J Cancer. 2007 Jul 1;121(1):175-83. PMID: 17330230

Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3.
Oncogene. 2004 Feb 26;23(8):1599-607. PMID: 14985701

Curcumin contributes to in vitro removal of iron by the chelation drug deferiprone.
Med Chem. 2007 Sep;3(5):469-74. PMID: 17897073

Curcumin contributes to overcoming multidrug resistance in human non-small cell lung carcinoma cell lines.
Cancer Biol Ther. 2008 Jul;7(7):1024-32. Epub 2008 Apr 4. PMID: 18414057

Curcumin contributes to programmed cell death in colon cancer cells.
Oncogene. 2002 Dec 5;21(55):8414-27. PMID: 12466962

Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells.
Mol Cell Biochem. 2011 Jan;347(1-2):1-11. Epub 2010 Oct 13. PMID: 20941532

Curcumin decrease cancer stem cells in a glioma cell line.
Cancer Lett. 2010 Jul 1;293(1):65-72. Epub 2010 Jan 20. PMID: 20089354

Curcumin decreases acid sphingomyelinase activity associated with proliferation in colon cancer.
Zhongguo Zhen Jiu. 2005 Aug;25(8):549-50. PMID: 17583825

Curcumin decreases specificity protein expression in bladder cancer cells, indicating it may have anti-cancer properties.
Cancer Res. 2008 Jul 1;68(13):5345-54. PMID: 18593936

Curcumin decreases survival of liver and breast cancer cells.
Strahlenther Onkol. 2011 Jul ;187(7):393-400. Epub 2011 Jun 27. PMID: 21713389

Curcumin derivatives appear to suppress genetic changes associated with colorectal cancer.
Biochem Biophys Res Commun. 2008 Dec 26;377(4):1304-8. Epub 2008 Nov 10. PMID: 19000900

Curcumin displays anti-cancer activity in endometrial cell lines.
J Cell Biochem. 2010 May 15;110(2):447-56. PMID: 20235152

Curcumin displays chemosensitzing activity in combination with paclitaxel.
Int J Biochem Cell Biol. 2010 Sep 29. Epub 2010 Sep 29. PMID: 20883815

Curcumin displays therapeutic activity in experimental studies of acute and chronic diseases characterized by an exaggerated inflammatory reaction.
Horm Behav. 1978 Feb;10(1):54-60. PMID: 16387899

Curcumin displays therapeutic properties in an experimental model of osteoarthritis.
Ann N Y Acad Sci. 2009 Aug;1171:428-35. PMID: 19723086

Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition.
Gynecol Oncol. 2011 Jul ;122(1):141-8. Epub 2011 Mar 29. PMID: 21450334

Curcumin down-regulates cancer-associated NF-kappab B activation and Cox-2 expression in precancerous and cancerous oral cells.
Toxicology. 2006 Nov 10;228(1):1-15. Epub 2006 Aug 12. PMID: 16996673

Curcumin down-regulates inflammation-associated chemicals in a mouse model of irritable bowel disease.
Di Yi Jun Yi Da Xue Xue Bao. 2004 Dec;24(12):1353-8. PMID: 15604057

Curcumin down-regulates multidrug-resistance.
Cancer Lett. 2008 Jan 18;259(1):111-8. Epub 2007 Nov 19. PMID: 18006147

Curcumin down-regulates processes associated wtih cancer metastasis.
Mol Pharmacol. 2006 Jan;69(1):195-206. Epub 2005 Oct 11. PMID: 16219905

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.
J Pharm Pharmacol. 2010 Feb;62(2):241-6. PMID: 11753638

Curcumin downregulates the constitutive activity of NF-kappaB and induces programmed cell death in novel mouse melanoma cells.
Melanoma Res. 2007 Oct;17(5):274-83. PMID: 17885582

Curcumin enhances cell death in glioma cells and neurogensis of neural progenitor cells.
Stem Cells Dev. 2006 Apr;15(2):165-74. PMID: 16646663

Curcumin enhances chemotherapeutic agents in prostate cancer cells.
Prostate. 2002 May 15;51(3):211-8. PMID: 11967955

Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells.
Int J Cancer. 2011 Feb 15;128(4):951-61. PMID: 20473900

Curcumin enhances indinavir antiretroviral activity in HIV-1 persistently infected cells.
Arch Virol. 2008;153(3):561-5. Epub 2008 Jan 4. PMID: 18175040

Curcumin enhances leukemia cell differentiation.
Oncol Res. 1997;9(1):31-9. PMID: 9112258

Curcumin enhances programmed cell death in chemoresistant ovarian cancer cells.
Gynecol Oncol. 2007 Apr;105(1):104-12. Epub 2006 Dec 15. PMID: 17174384

Curcumin enhances programmed cell death in Epstein-Barr Virus transformed B-cell lymphoma.
J Surg Res. 1999 Nov;87(1):1-5. PMID: 10527697

Curcumin enhances programmed cell death in leukemia cells.
J Huazhong Univ Sci Technolog Med Sci. 2003;23(2):124-6. PMID: 12973926

Curcumin enhances programmed cell death in lymphoma cells.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2005 Aug;13(4):624-7. PMID: 16129047

Curcumin enhances the anticancer activity of valproic acid in human leukemia cells.
Eur J Pharm Sci. 2010 Oct 9;41(2):210-8. Epub 2010 Jun 25. PMID: 20600877

Curcumin enhances the antiproliferative and pro-apoptic activity of HDAC inhibitors.
Cell Mol Life Sci. 2010 Mar;67(6):995-1004. Epub 2009 Dec 29. PMID: 20039095

Curcumin enhances the effectiveness of doxorubicin.
Pharmazie. 2011 Nov ;66(11):871-4. PMID: 22204133

Curcumin enhances the effects of 5-fluorouracil and oxaliplatin (FOLFOX) in mediating growth inhibition of colon cancer cells.
Int J Cancer. 2008 Jan 15;122(2):267-73. PMID: 17918158

Curcumin enhances the functional competence of the cystic-fibrosis associated gene, indicating it may have value for the condition.
Biochem Biophys Res Commun. 2007 Feb 9;353(2):351-6. Epub 2006 Dec 13. PMID: 17178109

Curcumin enhances TRAIL-induced programmed cell death in prostate cancer cells.
Mol Cancer Ther. 2003 Jan;2(1):95-103. PMID: 12533677

Curcumin enhances ultrasound-induced cell death in nasopharyngeal carcinoma cells.
Integr Cancer Ther. 2010 Aug 11. Epub 2010 Aug 11. PMID: 20702493

Curcumin exerts a synergistic effect with radiation against oral cancer cells.
Acta Odontol Scand. 2011 Feb 7. Epub 2011 Feb 7. PMID: 21294671

Curcumin exerts anti-apoptotic and anti-catabolic effects on IL-1beta-stimulated articular chondrocytes, indicating is may have therapeutic value in the treatment of osteoarthritis and related osteoarticular disorders.
Ann Anat. 2005 Nov;187(5-6):487-97. PMID: 16320828

Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas.
BMC Cancer. 2010;10:491. Epub 2010 Sep 14. PMID: 20840775

Curcumin exerts multiple suppressive effects on human breast carcinoma cells.
Int J Cancer. 2002 Mar 10;98(2):234-40. PMID: 11857414

Curcumin exhibits anti-allergic properties.
Anat Cell Biol. 2010 Mar;43(1):36-43. Epub 2010 Mar 31. PMID: 21190003

Curcumin exhibits anti-angiogenic activities.
Biochem Biophys Res Commun. 2002 Oct 4;297(4):934-42. PMID: 12359244

Curcumin exhibits anti-angiogenic activity.
Cell Growth Differ. 1998 Apr;9(4):305-12. PMID: 9563850

Curcumin exhibits anti-angiogenic properties.
Int J Oncol. 2002 Aug;21(2):379-83. PMID: 12118335

Curcumin exhibits anti-bacterial activity against E. coli cells.
J Pharm Sci. 2011 Jan;100(1):174-85. Epub 2010 Jun 23. PMID: 20575064

Curcumin exhibits anti-bacterial properties.
Eur J Med Chem. 2010 Sep;45(9):4209-14. Epub 2010 Jun 22. PMID: 20615583

Curcumin exhibits anti-bone metastatic activity in prostate cancer cells.
Prostate. 2004 Jun 15;60(1):1-17. PMID: 15129424

Curcumin exhibits anti-breast cancer properties.
Biochim Biophys Acta. 2007 Jul;1773(7):1116-23. Epub 2007 May 1. PMID: 17555831

Curcumin exhibits anti-cancer activity against acute T cell leukemia cells.
Bioorg Med Chem. 2003 Mar 20;11(6):1057-63. PMID: 12614893

Curcumin exhibits anti-cancer activity against highly metastatic melanoma cells.
Mol Pharmacol. 2009 Dec;76(6):1238-45. Epub 2009 Sep 24. PMID: 19779032

Curcumin exhibits anti-cancer activity against promyelocytic leukemia and submandibular cancer cells.
Anticancer Res. 2005 Nov-Dec;25(6B):4029-36. PMID: 16309195

Curcumin exhibits anti-cancer effects on gene expression in human colon cancer cells.
J Carcinog. 2004 May 12;3(1):8. Epub 2004 Aug 12. PMID: 15140256

Curcumin exhibits anti-cancer properties in breast cancer cells.
Biochem Pharmacol. 1998 Jul 15;56(2):197-206. PMID: 9698073

Curcumin exhibits anti-cancer properties in gastric and colon cancer cells.
Anticancer Res. 2001 Mar-Apr;21(2A):873-8. PMID: 11396178

Curcumin exhibits anti-cancer, anti-inflammatory and antioxidant activities.
Phytomedicine. 2000 Jul;7(4):303-8. PMID: 10969724

Curcumin exhibits anti-cataract activity in the diabetic rat lens.
Mol Vis. 2005;11:561-8. Epub 2005 Jul 26. PMID: 16088325

Curcumin exhibits anti-glioma properties.
Cancer Sci. 2011 Dec 22. Epub 2011 Dec 22. PMID: 22192169

Curcumin exhibits anti-HIV activity.
Res Virol. 1998 Jan-Feb;149(1):43-52. PMID: 9561563

Curcumin exhibits anti-inflammatory and anti-atherosclerotic properties.
Eur J Pharmacol. 1992 Oct 20;221(2-3):381-4. PMID: 1426014

Curcumin exhibits anti-inflammatory properties in leukemia cells.
Ann N Y Acad Sci. 2009 Aug;1171:391-8. PMID: 19723081

Curcumin exhibits anti-inflammatory properties in rat brain homegenates.
Mol Cell Biochem. 1994 Nov 9;140(1):73-9. PMID: 7877600

Curcumin exhibits anti-leukemia activity.
Cancer Chemother Pharmacol. 2008 Sep;62(4):585-94. Epub 2007 Nov 23. PMID: 18034345

Curcumin exhibits anti-leukemia activity.
Biochem Pharmacol. 2006 Nov 30;72(11):1547-54. Epub 2006 Sep 7. PMID: 16959222

Curcumin exhibits anti-leukemia activity.
Arch Pharm Res. 2006 Jan;29(1):80-7. PMID: 16491848

Curcumin exhibits anti-leukemia properties.
Nutr Cancer. 2000;38(1):131-8. PMID: 11341039

Curcumin exhibits anti-leukemia properties.
Biochem Biophys Res Commun. 2007 Feb 23;353(4):1040-5. Epub 2006 Dec 27. PMID: 17198682

Curcumin exhibits anti-metastatic properties in breast cancer cells.
Carcinogenesis. 2008 Apr;29(4):779-89. Epub 2007 Nov 13. PMID: 17999991

Curcumin exhibits anti-obesity properties in vitro.
Mol Cell Biochem. 2011 Jan 9. Epub 2011 Jan 9. PMID: 21221723

Curcumin exhibits anti-proliferative effects of curcumin against breast cancer.
Eur J Pharmacol. 2010 Jul 10;637(1-3):16-21. Epub 2010 Apr 10. PMID: 20385124

Curcumin exhibits anti-prostate cancer activity.
Prostate Cancer Prostatic Dis. 2010 Dec;13(4):343-9. Epub 2010 Aug 3. PMID: 20680030

Curcumin exhibits anti-prostate cancer cell activity.
Int J Oncol. 2002 Oct;21(4):825-30. PMID: 12239622

Curcumin exhibits anti-rheumatoid activity.
Eur J Pharmacol. 2009 Jun 10;612(1-3):161-6. Epub 2009 Apr 14. PMID: 19371737

Curcumin exhibits anti-transmissible spongiform encephalopathy activity.
J Virol. 2003 May;77(9):5499-502. PMID: 12692251

Curcumin exhibits anticancer activity on B lymphoma cells.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2006 Apr;14(2):293-7. PMID: 16638200

Curcumin exhibits anticancer and ant-metastatic activity in prostate cancer cells.
Cell Motil Cytoskeleton. 2004 Aug;58(4):253-68. PMID: 15236356

Curcumin exhibits anticarcinogenic and anti-inflammatory properties.
Arterioscler Thromb Vasc Biol. 1997 Dec;17(12):3406-13. PMID: 9437186

Curcumin exhibits antifungal activity against Candida albicans.
Biosci Rep. 2009 Dec 17. Epub 2009 Dec 17. PMID: 20017731

Curcumin exhibits antimetastatic properties.
Rev Med Chil. 1999 Mar;127(3):286-94. PMID: 12678405

Curcumin exhibits B-cell lymphoma cell proliferation.
Ai Zheng. 2006 May;25(5):582-6. PMID: 16687078

Curcumin exhibits both anti-proliferative and anti-inflammatory activities.
Neurotox Res. 2006 Jan;9(1):29-37. PMID: 16464750

Curcumin exhibits chemopreventive properties against cholangiocarcinoma cells.
Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2265-72. Epub 2010 May 25. PMID: 20510329

Curcumin exhibits chemopreventive properties in normal skin cells.
J Biol Chem. 2007 Mar 2;282(9):6707-15. Epub 2006 Dec 5. PMID: 17148446

Curcumin exhibits chemosensitizing properties against multidrug resistance in rat liver cells.
Life Sci. 1998;62(25):2349-58. PMID: 9651124

Curcumin exhibits cytoprotective properties against shiga toxin.
Biochem Biophys Res Commun. 2001 Apr 27;283(1):36-41. PMID: 11322764

Curcumin exhibits cytotoxic activity against Giardia lamblia trophozoites.
Biomed Pharmacother. 1990;44(10):511-4. PMID: 16678799

Curcumin exhibits cytotoxicity to the malaria parasite.
Antimicrob Agents Chemother. 2007 Feb;51(2):488-94. Epub 2006 Dec 4. PMID: 17145789

Curcumin exhibits estrogen-like activity.
Cell Physiol Biochem. 2010;26(3):471-82. Epub 2010 Aug 24. PMID: 20798532

Curcumin exhibits histone deacetylase inhibitor activity in malignant hematologic cells.
J Huazhong Univ Sci Technolog Med Sci. 2009 Feb;29(1):25-8. Epub 2009 Feb 18. PMID: 19224157

Curcumin exhibits immunomodulatory and immunostimulatory activities.
Immunol Invest. 1999 Sep-Dec;28(5-6):291-303. PMID: 10574627

Curcumin exhibits inhibitory effects on Alzheimer disease associated ß-amyloid proteins.
Int Dent J. 1996 Feb;46(1):22-34. PMID: 20727383

Curcumin exhibits liver-protective properties against alcohol cytotoxicity.
J Ethnopharmacol. 2004 Nov;95(1):31-7. PMID: 15374604

Curcumin exhibits potential anti-cancer activities.
Cancer Lett. 1996 Oct 1;107(1):109-15. PMID: 8913274

Curcumin exhibits protective properties against peroxynitrite-induced neurotoxicity.
Neurotoxicology. 2011 Jan;32(1):150-7. Epub 2010 Sep 24. PMID: 20869986

Curcumin exhibits therapeutic promise for prostate cancer.
Genes Nutr. 2009 Oct 6. Epub 2009 Oct 6. PMID: 19806380

Curcumin exhibits therapeutic value in non-small cell lung cancer.
Apoptosis. 2010 Feb 2. Epub 2010 Feb 2. PMID: 20127174

Curcumin from turmeric inhibits bladder cancer cells and development of urothelial tumors in a rat bladder carcinogenesis model.
Ann Nutr Metab. 2009;54(4):283-90. Epub 2009 Jul 27. PMID: 18342436

Curcumin has a cytoprotective effect against paracetomol-induced cytotoxicity.
Biochem Pharmacol. 1990 Jun 15;39(12):1869-75. PMID: 2353930

Curcumin has a phototoxic effect on methicillin-resistant Staphylococcus aureus.
Lasers Med Sci. 2012 Feb 23. Epub 2012 Feb 23. PMID: 22358772

Curcumin has a preventive effect on chemically-induced breast cancer.
Carcinogenesis. 1998 Jun;19(6):1039-43. PMID: 9667742

Curcumin has a prooxidant action on promyelocytic leukemia cells.
Helicobacter. 2009 Jun;14(3):202-7. PMID: 15465643

Curcumin has a protective effect against neuronal damage associated with metal ions.
Neurosci Lett. 2008 Aug 8;440(3):344-7. Epub 2008 May 24. PMID: 18583042

Curcumin has a protective effect against oxidative damage on skin cells.
J Trauma. 2001 Nov;51(5):927-31. PMID: 11706342

Curcumin has a protective role in cardiovascular diseases.
Int J Cardiol. 2009 Apr 3;133(2):145-51. Epub 2009 Feb 23. PMID: 19233493

Curcumin has a significant role in a therapeutic application for the prevention or progression of diabetic complications in the cerebellum.
Life Sci. 2009 Nov 4;85(19-20):704-10. Epub 2009 Oct 3. PMID: 19804785

Curcumin has a synergistic antitumor effect in combination with docetaxel against lung cancer.
Acta Biochim Biophys Sin (Shanghai). 2012 Feb ;44(2):147-53. Epub 2011 Nov 29. PMID: 22126905

Curcumin has a wide range of potential anti-obesity properties.
Eur J Nutr. 2011 Apr ;50(3):151-61. Epub 2011 Mar 27. PMID: 21442412

Curcumin has an anti-fibrotic effect in rat hepatic stellate cells.
Phytother Res. 2009 Jul;23(7):927-32. PMID: 19152370

Curcumin has an anti-inflammatory effect in macrophages stimulated by lipopolysaccharides from the periodontitis pathogen Porphyromonas gingivalis.
Pharmacology. 2008;82(4):264-9. Epub 2008 Oct 10. PMID: 18849645

Curcumin has an anticancer effect of on human B cell non-Hodgkin's lymphoma.
Thromb Res. 2009 Mar;123(5):740-4. Epub 2008 Sep 10. PMID: 16196288

Curcumin has an antiproliferative effect in human lung cancer cells.
Zhong Yao Cai. 2004 Dec;27(12):923-7. PMID: 15807244

Curcumin has an inhibitory effect on angiogenesis induced by brain derived neurotrophic factor from multiple myeloma cells.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2006 Feb;14(1):70-4. PMID: 16584595

Curcumin has an inhibitory effect on oral cancer cells.
Phytother Res. 2010 Apr;24(4):577-82. PMID: 19777504

Curcumin has ant-allergic activities.
Biol Pharm Bull. 2005 Aug;28(8):1438-43. PMID: 16079489

Curcumin has anti-angiogenic properties.
Invest Ophthalmol Vis Sci. 2006 May;47(5):2179-84. PMID: 16639030

Curcumin has anti-angiogenic properties.
Exp Aging Res. 2005 Jan-Mar;31(1):55-67. PMID: 14650061

Curcumin has anti-angiogenic properties.
Chem Biol. 2003 Aug;10(8):695-704. PMID: 12954328

Curcumin has anti-breast cancer activity related to the activities of protein kinases on cell signal pathway.
Zhong Yao Cai. 2009 May;32(5):728-32. PMID: 19771847

Curcumin has anti-breast cancer activity.
J Exp Ther Oncol. 2010;8(3):261-6. PMID: 20734924

Curcumin has anti-cancer activity against drug-resistant chronic myeloid leukemia cells.
Mol Cancer Res. 2006 Jul;4(7):457-69. PMID: 16849521

Curcumin has anti-cancer activity against gllioblastoma cells.
Biochem Biophys Res Commun. 2008 Oct 17;375(2):275-9. Epub 2008 Aug 13. PMID: 20596601

Curcumin has anti-cancer activity in human tongue cancer.
Cell Biochem Funct. 2011 Sep 1. Epub 2011 Sep 1. PMID: 21887696

Curcumin has anti-cancer properties.
J Agric Food Chem. 2007 Dec 12;55(25):10194-9. Epub 2007 Nov 8. PMID: 15008515

Curcumin has anti-carcinogenic properties on colorectal cancer.
World J Gastrointest Oncol. 2010 Apr 15;2(4):169-76. PMID: 21160593

Curcumin has anti-endometrial cancer activity.
Gynecol Oncol. 2007 Sep;106(3):541-8. Epub 2007 Jun 27. PMID: 17590421

Curcumin has anti-fibrotic properties.
Zhong Yao Cai. 2009 May;32(5):732-5. PMID: 19771848

Curcumin has anti-fungal properties.
J Agric Food Chem. 2003 Mar 12;51(6):1578-81. PMID: 12617587

Curcumin has anti-glioma properties.
J Neurooncol. 2007 Dec;85(3):263-70. Epub 2007 Jun 27. PMID: 17594054

Curcumin has anti-inflammatory properties.
J Ethnopharmacol. 2004 Jul;93(1):113-6. PMID: 11544338

Curcumin has anti-inflammatory properties.
Pharmacol Res. 1999 Jan;39(1):41-7. PMID: 10051376

Curcumin has anti-inflammatory properties.
J Huazhong Univ Sci Technolog Med Sci. 2004;24(6):628-9. PMID: 10477620

Curcumin has anti-invasive and anti-metastatic activity in lung cancer cells.
Mol Pharmacol. 2004 Jan;65(1):99-110. PMID: 14722241

Curcumin has anti-Leishmanial activity.
Parasitol Res. 2005 Apr;96(1):49-56. Epub 2005 Mar 17. PMID: 15772867

Curcumin has anti-leukemia properties.
J Nat Prod. 2007 Dec;70(12):1884-8. Epub 2007 Dec 13. PMID: 18076140

Curcumin has anti-mutagenic properties against environmental mutagens.
Food Chem Toxicol. 1987 Jul;25(7):545-7. PMID: 3623345

Curcumin has anti-pancreatic and lung cancer activity.
Anticancer Res. 2006 Nov-Dec;26(6B):4423-30. PMID: 17201164

Curcumin has anti-platelet activity.
Platelets. 2010 Feb 16. Epub 2010 Feb 16. PMID: 20158382

Curcumin has anti-proliferative activity in androgen-dependent prostate cancer cells.
Int J Oncol. 2011 Mar;38(3):603-11. Epub 2011 Jan 14. PMID: 21240460

Curcumin has anti-proliferative activity on human breast cancer cells.
Can Fam Physician. 1993 Nov;39:2362-7. PMID: 14642080

Curcumin has antibiotic/antifungal activity against foodborne pathogens.
Int J Food Microbiol. 2009 Nov 30;136(1):71-4. Epub 2009 Sep 8. PMID: 19775769

Curcumin has anticancer activity in human liver cancer cell lines.
Zhongguo Zhong Yao Za Zhi. 2010 Feb;35(4):485-8. PMID: 20450049

Curcumin has anticancer activity on human Burkitt's lymphoma cells.
Zhonghua Zhong Liu Za Zhi. 2002 Jul;24(4):348-52. PMID: 12408761

Curcumin has antifungal activity.
J Antimicrob Chemother. 2009 Feb;63(2):337-9. Epub 2008 Nov 26. PMID: 19038979

Curcumin has antimutagenic activity.
Int J Antimicrob Agents. 2008 Jun;31(6):572-6. Epub 2008 Apr 28. PMID: 10682600

Curcumin has antimutagenic potential on chromosomal aberrations in other plants such as onion.
Hum Mol Genet. 2006 Sep 15;15(18):2743-51. Epub 2006 Aug 7. PMID: 17610326

Curcumin has antimutagenic potential.
Mutat Res. 2002 Mar 25;515(1-2):197-202. PMID: 11909768

Curcumin has antioxidant activity.
Mutat Res. 1994 Dec 1;311(2):249-55. PMID: 7526190

Curcumin has antiproliferative effects against human breast tumor cell lines.
Anticancer Drugs. 1997 Jun;8(5):470-81. PMID: 9215611

Curcumin has antitumor activity against human osteosarcoma cells.
Invest New Drugs. 2010 Dec;28(6):766-82. PMID: 19730790

Curcumin has been demonstrated to be safe in six human trials and has demonstrated anti-inflammatory activity.
J Altern Complement Med. 2003 Feb;9(1):161-8. PMID: 12676044

Curcumin has chemopreventive properties in nicotine-induced proliferation and angiogenesis in llung cancer cells.
Mol Cancer. 2010;9:220. Epub 2010 Aug 20. PMID: 20727180

Curcumin has chemoprotective effects in esophageal epithelial cells exposed to bile acids.
World J Gastroenterol. 2010 Sep 7;16(33):4152-8. PMID: 20806431

Curcumin has chemosensitizing activity in multidrug resistant tumor cell lines.
Zhong Yao Cai. 2001 Sep;24(9):655-7. PMID: 11799777

Curcumin has heat shock inducing properties.
Ann N Y Acad Sci. 2006 May;1067:394-9. PMID: 16804017

Curcumin has immunomodulatory effects in allergy.
Mol Nutr Food Res. 2008 Sep;52(9):1031-9. PMID: 18398870

Curcumin has leischmaniacidal activity in vitro.
Biol Pharm Bull. 2002 Mar;25(3):386-9. PMID: 11913540

Curcumin has leishmanicidal activity.
Biol Pharm Bull. 2002 Jan;25(1):131-3. PMID: 11824543

Curcumin has multiple molecular mechanisms as a chemopreventive.
AAPS J. 2006;8(3):E443-9. Epub 2006 Jul 7. PMID: 17025261

Curcumin has neuroprotective properties against NMDA-induced toxicity.
Invest Ophthalmol Vis Sci. 2010 Sep 22. Epub 2010 Sep 22. PMID: 20861489

Curcumin has neuroprotective properties.
Prog Neuropsychopharmacol Biol Psychiatry. 2010 Feb 1;34(1):147-53. Epub 2009 Oct 29. PMID: 19879308

Curcumin has nutritional potential as a naturally occurring anti-inflammatory agent for treating osteoarthritis.
Biochem Pharmacol. 2007 May 1;73(9):1434-45. Epub 2007 Jan 7. PMID: 17291458

Curcumin has potent antiproliferative and proapoptotic effects in melanoma cells.
Cancer. 2005 Aug 15;104(4):879-90. PMID: 16007726

Curcumin has potential as an effective modifier in therapy of leukemia and/or as an immunopotentiator.
Biochem Biophys Res Commun. 2010 Apr 23;395(1):61-5. Epub 2010 Mar 25. PMID: 20346917

Curcumin has potential for hepatic fibrosis therapy.
J Clin Rheumatol. 2010 Feb 2. Epub 2010 Feb 2. PMID: 18037917

Curcumin has profound immunosuppressive effects of potential value in organ transplantation.
J Surg Res. 2004 Oct;121(2):171-7. PMID: 15501456

Curcumin has radioprotective properties.
J Ethnopharmacol. 1999 Jan;64(1):1-7. PMID: 10075116

Curcumin has radioprotective properties.
Biophys Chem. 2001 Aug 30;92(1-2):119-26. PMID: 11527584

Curcumin has radiosensitizing and chemosensitizing effects on tumors while protecting healthy tissue from damage.
Nutr Cancer. 2010 Oct;62(7):919-30. PMID: 20924967

Curcumin has remarkable antiviral effects on HSV-1 in cell culture.
Anticancer Res. 2001 Mar-Apr;21(2A):873-8. PMID: 21299124

Curcumin has schistosomicidal activity.
Acta Pharmacol Sin. 2009 Mar;30(3):227-81. PMID: 19096877

Curcumin has significant inhibitory effects on the growth of oral cancer cells in vitro.
Anticancer Res. 2000 May-Jun;20(3A):1733-8. PMID: 10928101

Curcumin has therapeutic potential in prostate cancer.
Mol Urol. 2000;4(1):1-6. PMID: 10851300

Curcumin has therapeutic value in inflammatory bowel disease.
Inflamm Bowel Dis. 2011 Feb;17(2):503-15. PMID: 20629184

Curcumin has therapeutic value in the prevention and treatment of liver diseases or damage.
Liver Int. 2009 Nov;29(10):1457-66. PMID: 19811613

Curcumin has trypanocidal properties.
Biol Pharm Bull. 1998 Jun;21(6):643-5. PMID: 9657056

Curcumin improves chemotherapy by simultaneously sensitising cancer cells and reducing side effects.
Eur J Cancer. 2011 May 24. Epub 2011 May 24. PMID: 21616659

Curcumin improves the antitumor effect of X-ray irradiation.
Anticancer Drugs. 2012 Jan 23. Epub 2012 Jan 23. PMID: 22273827

Curcumin increases the radiosensitivity of colorectal cancer cells.
Int J Radiat Oncol Biol Phys. 2009 Oct 1;75(2):534-42. PMID: 19735878

Curcumin induces a tolerogenic phenotype in immune cells.
Clin Exp Immunol. 2010 Dec;162(3):460-73. PMID: 21070208

Curcumin induces apoptosis in human neuroblastoma cells.
Fitoterapia. 2005 Sep;76(6):508-13. PMID: 18383847

Curcumin induces apoptosis in primary resting B chronic lymphocytic leukemia cells.
Leuk Lymphoma. 2009 Apr;50(4):625-32. PMID: 19373661

Curcumin induces apoptosis of triple-negative breast cancer cells.
Mol Med Report. 2012 Sep 26. Epub 2012 Sep 26. PMID: 23023821

Curcumin induces cell cycle arrest and programmed cell death in cisplatin-resistant human ovarian cancer cells.
Cancer Biol Ther. 2007 Feb;6(2):178-84. Epub 2007 Feb 5. PMID: 17218783

Curcumin induces cell cycle arrest and programmed cell death in human osteosarcoma cells.
Anticancer Res. 2009 Dec;29(12):5039-44. PMID: 20044614

Curcumin induces cell death in cancer cells.
Mol Nutr Food Res. 2008 Sep;52(9):1074-81. PMID: 18720347

Curcumin induces cell death in human uveal melanoma cells.
Curr Eye Res. 2010 Apr;35(4):352-60. PMID: 20373902

Curcumin induces cell death in oesophageal cancer cells.
Br J Cancer. 2009 Nov 3;101(9):1585-95. Epub 2009 Oct 6. PMID: 19809435

Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth.
J Ovarian Res. 2010;3:11. Epub 2010 Apr 29. PMID: 20429876

Curcumin induces death in tumor cells.
Carcinogenesis. 2012 Jan 31. Epub 2012 Jan 31. PMID: 22298641

Curcumin induces DNA damage in triple negative breast cancer cells.
Breast Cancer (Auckl). 2010;4:1-3. Epub 2010 Feb 16. PMID: 20697527

Curcumin induces heat shock protein and inhibits p53 gene expression in colorectal cancer cells.
Pediatrics. 2005 May;115(5):1360-6. PMID: 8989916

Curcumin induces heat shock protein.
Crit Care Med. 2001 Nov;29(11):2199-204. PMID: 11700423

Curcumin induces programmed cell death and blocks migration of human medulloblastoma cells.
Anticancer Res. 2010 Feb;30(2):499-504. PMID: 20332461

Curcumin induces programmed cell death and cell cycle arrest in human prostate cancer cells.
Zhonghua Wai Ke Za Zhi. 2006 Sep 15;44(18):1256-9. PMID: 17147887

Curcumin induces programmed cell death and disturbs cell cycle progression in leukemia cells.
J Huazhong Univ Sci Technolog Med Sci. 2002;22(4):295-8. PMID: 12674762

Curcumin induces programmed cell death and growth inhibition in breast cancer cells.
Cochrane Database Syst Rev. 2005(4):CD004649. Epub 2005 Oct 19. PMID: 10445426

Curcumin induces programmed cell death in a murine mammary gland cells.
Eur J Pharmacol. 2011 Oct 1 ;668(1-2):127-32. Epub 2011 Jul 8. PMID: 21762689

Curcumin induces programmed cell death in a nasopharyngeal carcinoma cell line.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2006 Aug;41(8):612-6. PMID: 17039805

Curcumin induces programmed cell death in a variety of cancer cell lines.
Nutr Cancer. 1996;26(1):111-20. PMID: 8844727

Curcumin induces programmed cell death in an acute T cell leukemia cell line.
Exp Cell Res. 1999 Jun 15;249(2):299-307. PMID: 10366429

Curcumin induces programmed cell death in androgen-dependent prostate cancer cell lines.
Zhonghua Nan Ke Xue. 2006 Feb;12(2):141-4. PMID: 16519151

Curcumin induces programmed cell death in both androgen-dependent and androgen-independent prostate cancer cells.
Prostate Cancer Prostatic Dis. 2000 Aug;3(2):84-93. PMID: 12497104

Curcumin induces programmed cell death in breast cancer cells.
Mutat Res. 2002 Jun 27;518(1):71-84. PMID: 12063069

Curcumin induces programmed cell death in breast cancer cells.
Anticancer Res. 2005 Sep-Oct;25(5):3293-302. PMID: 16101141

Curcumin induces programmed cell death in breast cancer.
FEBS Lett. 2002 Feb 13;512(1-3):334-40. PMID: 11852106

Curcumin induces programmed cell death in Burkitt's lymphoma cell lines.
Mol Cancer Ther. 2008 Oct;7(10):3318-29. PMID: 18852135

Curcumin induces programmed cell death in chronic lymphocytic leukemia B cells and works synergistically with the green tea polypenol EGCG.
Clin Nephrol. 1975;3(5):195-203. PMID: 19228728

Curcumin induces programmed cell death in chronic myeloid leukemia cells.
J Asian Nat Prod Res. 2009 Nov;11(11):918-28. PMID: 20183254

Curcumin induces programmed cell death in colon cancer cells.
Carcinogenesis. 2006 Aug;27(8):1636-44. Epub 2006 Feb 25. PMID: 16501251

Curcumin induces programmed cell death in colon cancer cells.
J Zhejiang Univ Sci B. 2009 Feb;10(2):93-102. PMID: 19235267

Curcumin induces programmed cell death in follicular lymphoma cell lines.
Chem Pharm Bull (Tokyo). 2011;59(3):378-81. PMID: 16569593

Curcumin induces programmed cell death in glioma cells.
FEBS Lett. 2006 Jun 26;580(15):3746-52. Epub 2006 Jun 9. PMID: 16777101

Curcumin induces programmed cell death in hepatoma cells.
Asian Pac J Cancer Prev. 2011 ;12(8):1925-9. PMID: 22292626

Curcumin induces programmed cell death in histiocytoma tumor cells.
FEBS Lett. 1999 Feb 19;445(1):165-8. PMID: 10069393

Curcumin induces programmed cell death in human basal cell carcinoma cells.
J Invest Dermatol. 1998 Oct;111(4):656-61. PMID: 9764849

Curcumin induces programmed cell death in human bladder cells.
Anticancer Drugs. 2006 Mar;17(3):279-87. PMID: 16520656

Curcumin induces programmed cell death in human breast cancer cells.
Biochem Pharmacol. 2003 Feb 1;65(3):361-76. PMID: 12527329

Curcumin induces programmed cell death in human colon cancer cells.
Carcinogenesis. 2004 Nov;25(11):2183-9. Epub 2004 Jul 15. PMID: 15256484

Curcumin induces programmed cell death in human colon cancer cells.
Anticancer Res. 2006 Nov-Dec;26(6B):4379-89. PMID: 17201158

Curcumin induces programmed cell death in human colon cancer cells.
Cancer Lett. 2010 Nov 1;297(1):1-8. Epub 2010 May 15. PMID: 20472336

Curcumin induces programmed cell death in human colon cancer cells.
J Oral Maxillofac Surg. 2010 May;68(5):1158-61. PMID: 16302093

Curcumin induces programmed cell death in human liver cancer cells.
Oncogene. 1996 Aug 1;13(3):609-16. PMID: 8760302

Curcumin induces programmed cell death in human liver cancer cells.
Food Chem Toxicol. 2006 Jun;44(6):810-8. Epub 2005 Dec 5. PMID: 16537656

Curcumin induces programmed cell death in human lung adenocarcinoma cells.
Oncol Rep. 2010 Feb;23(2):397-403. PMID: 20043100

Curcumin induces programmed cell death in human malignant gliobastoma cells. - Article 1
Neurochem Res. 2007 Dec;32(12):2103-13. Epub 2007 Jun 12. PMID: 17562168

Curcumin induces programmed cell death in human melanoma cells.
Exp Cell Res. 2001 Dec 10;271(2):305-14. PMID: 11716543

Curcumin induces programmed cell death in human multidrug-resistant cells.
Ann N Y Acad Sci. 2002 Nov;973:250-4. PMID: 12485871

Curcumin induces programmed cell death in human non-small cell lung cancer cells.
Anticancer Res. 2010 Jun;30(6):2125-33. PMID: 20651361

Curcumin induces programmed cell death in human promyelocytic leukemia HL-60 cells.
Life Sci. 2008 Feb 13;82(7-8):367-75. Epub 2007 Dec 7. PMID: 18187158

Curcumin induces programmed cell death in Leishmania through its pro-oxidant and calcium-modulating activity.
Apoptosis. 2008 Jul;13(7):867-82. PMID: 18506627

Curcumin induces programmed cell death in leukemia cells.
Carcinogenesis. 2008 May;29(5):1042-8. Epub 2008 Mar 13. PMID: 11756235

Curcumin induces programmed cell death in leukemia cells.
Biochem Pharmacol. 2003 Oct 15;66(8):1475-83. PMID: 14555224

Curcumin induces programmed cell death in lung cancer cells through cytoskeleton disorganization.
Planta Med. 2009 Jun;75(8):808-13. Epub 2009 Mar 5. PMID: 19266427

Curcumin induces programmed cell death in lung cancer cells.
Oncol Rep. 2010 May;23(5):1285-92. PMID: 20372842

Curcumin induces programmed cell death in lung cancer cells.
Phytother Res. 2009 Dec 9. PMID: 20686221

Curcumin induces programmed cell death in mantle cell lymphoma.
Leuk Lymphoma. 2011 Aug ;52(8):1537-43. Epub 2011 Jun 24. PMID: 21699455

Curcumin induces programmed cell death in medullobastoma cells.
Mol Carcinog. 2009 Dec 18. Epub 2009 Dec 18. PMID: 20025076

Curcumin induces programmed cell death in mouse breast cancer cells.
Biochem Biophys Res Commun. 2001 Nov 2;288(3):658-65. PMID: 11676493

Curcumin induces programmed cell death in prostate cancer cells.
Nutr Cancer. 2010 Apr;62(3):379-89. PMID: 20358476

Curcumin induces programmed cell death in triple negative breast cancer cell lines.
Breast Cancer. 2009 Sep 2;3:61-75. PMID: 19809577

Curcumin induces programmed cell death in two leukemia cell lines.
Ann N Y Acad Sci. 2003 Dec;1010:389-92. PMID: 15033758

Curcumin induces programmed cell death ina human nasopharyngeal carcinoma cell line.
Ai Zheng. 2004 Dec;23(12):1651-4. PMID: 15601554

Curcumin induces suppression of an oncogene associated with the promotion of various cancers.
Oncogene. 2002 Dec 12;21(57):8852-61. PMID: 12483537

Curcumin inhibit human lung cancer cells.
Mol Biol Rep. 2010 Oct;37(7):3105-10. Epub 2009 Oct 15. PMID: 19826913

Curcumin inhibit the growth of hormone-independent and multi-drug resistant breast cancer cells.
Ann N Y Acad Sci. 2009 Feb;1155:278-83. PMID: 19250217

Curcumin inhibit the growth of human astroglioma cells.
Biochem Biophys Res Commun. 2005 Oct 7;335(4):1017-25. PMID: 16102725

Curcumin inhibits a human multiple myeloma cell line.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Aug;15(4):762-6. PMID: 17708799

Curcumin inhibits ACTH- and angiotensin II-stimulated cortisol secretion.
J Nat Prod. 2009 Aug;72(8):1533-7. PMID: 19653644

Curcumin inhibits acute T cell leukemia in vitro.
Mol Cancer Ther. 2006 Apr;5(4):927-34. PMID: 16648563

Curcumin inhibits aflatoxin-associated DNA adduct formation associated with liver carcinogenesis.
Chem Biol Interact. 1996 Mar 8;100(1):41-51. PMID: 8599854

Curcumin inhibits B-cell lymphoma cells.
Chin Med J (Engl). 2005 Dec 20;118(24):2052-7. PMID: 16438902

Curcumin inhibits bTREK-1 K+ channels and stimulates cortisol secretion from adrenocortical cells.
Biochem Biophys Res Commun. 2008 Jun 13;370(4):623-8. Epub 2008 Apr 10. PMID: 18406348

Curcumin inhibits carcinogen and nicotine-induced head and neck squamous cell carcinoma.
Cancer Prev Res (Phila). 2010 Dec;3(12):1586-95. Epub 2010 Sep 17. PMID: 20851953

Curcumin inhibits cell migration of human colon cancer cells.
Anticancer Res. 2006 Mar-Apr;26(2A):1281-8. PMID: 16619535

Curcumin inhibits cell proliferation by inducing programmed cell death in lymphoma cells.
Trends Endocrinol Metab. 2009 Apr;20(3):139-45. Epub 2009 Mar 9. PMID: 20863651

Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing programmed cell death in colon carcinoma cells.
Maturitas. 2008 Feb 20;59(2):137-48. Epub 2008 Mar 4. PMID: 10625938

Curcumin inhibits cervical cancer associated HPV-infection.
Br J Nutr. 2007 Oct;98(4):720-6. Epub 2007 Aug 1. PMID: 15514944

Curcumin inhibits chemically-induced oxidative stress associated with a tumor-promoting agent.
Carcinogenesis. 1994 Aug;15(8):1717-21. PMID: 8055654

Curcumin inhibits cholesterol uptake.
Lipids Health Dis. 2010;9:40. Epub 2010 Apr 19. PMID: 20403165

Curcumin inhibits chronic myelogenous leukemia cells (K562).
J Altern Complement Med. 2007 Nov;13(9):985-7. PMID: 15182583

Curcumin inhibits cortisone-induced cytoxicity in vitro.
Basic Clin Pharmacol Toxicol. 2009 Mar;104(3):236-40. Epub 2009 Jan 20. PMID: 19175364

Curcumin inhibits cyclooxygenase and matrix metalloproteinase-8 expression associated with breast cancer progrression.
Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1612-20. PMID: 16356124

Curcumin inhibits cyclooxygenase-2 expression in human colon cancer cells.
Cancer Lett. 2001 Oct 30;172(2):111-8. PMID: 11566484

Curcumin inhibits cytokines associated with allergic diseases.
Biochem Pharmacol. 1997 Oct 1;54(7):819-24. PMID: 9353136

Curcumin inhibits EBV reactivation in vitro.
Mol Carcinog. 2002 Mar;33(3):137-45. PMID: 11870879

Curcumin inhibits embryonal carcinoma.
Int J Nurs Pract. 2010 Oct;16(5):454-60. PMID: 11686235

Curcumin inhibits endotoxin-associated changes in rat genes.
J Pharmacol Exp Ther. 2003 Dec;307(3):1205-12. Epub 2003 Oct 13. PMID: 14557382

Curcumin inhibits epidermal growth factor receptor activity in human epidermoid cancer cells.
Biochim Biophys Acta. 1994 Dec 30;1224(3):597-600. PMID: 7803521

Curcumin inhibits esophageal activation in response to acid.
Am J Physiol Gastrointest Liver Physiol. 2009 Feb;296(2):G388-98. Epub 2008 Dec 12. PMID: 19074641

Curcumin inhibits Ewing sarcoma.
Med Oncol. 2010 Dec;27(4):1096-101. Epub 2009 Oct 27. PMID: 19859844

Curcumin inhibits gastrointestinal hormone (e.g., neurotensin)-induced chemokine expression and cell migration associated with human colon cancer cell progression.
Clin Cancer Res. 2006 Sep 15;12(18):5346-55. PMID: 17000667

Curcumin inhibits glucose production in isolated mice hepatocytes.
Diabetes Res Clin Pract. 2008 May;80(2):185-91. Epub 2008 Jan 24. PMID: 18221818

Curcumin inhibits glutamate-induced excitoxicity in vitro.
Mol Cell Biochem. 2007 Apr;298(1-2):187-94. Epub 2006 Nov 25. PMID: 17131042

Curcumin inhibits gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection.
Biol Chem. 2005 May;386(5):481-90. PMID: 15927892

Curcumin inhibits growth and induces programmed cell death in human ovarian cancer cell lines.
Chin J Integr Med. 2006 Jun;12(2):126-31. PMID: 16800992

Curcumin inhibits growth and sensitizes ovarian cancer cells to cisplatin-mediated killing.
Carcinogenesis. 1982;3(11):1331-8. PMID: 12447990

Curcumin inhibits growth, induces cell cycle arrest and programmed cell death in human prostatic stromal cells.
Zhongguo Zhong Yao Za Zhi. 2008 Aug;33(16):2022-5. PMID: 19086645

Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT.
Int J Mol Med. 2012 Nov ;30(5):1021-8. Epub 2012 Aug 20. PMID: 22922731

Curcumin inhibits head and neck cancer cell proliferation.
Int J Cancer. 2006 Sep 15;119(6):1268-75. PMID: 16642480

Curcumin inhibits head and neck squamous cell cancer cells.
Int J Cancer. 2004 Sep 20;111(5):679-92. PMID: 15252836

Curcumin inhibits Helicobacter pylori.
Anticancer Res. 2002 Nov-Dec;22(6C):4179-81. PMID: 12553052

Curcumin inhibits hepatic fibrogenesis.
Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G113-23. Epub 2006 Sep 7. PMID: 16959952

Curcumin inhibits hepatitis B virus.
FEBS Lett. 2010 Jun 3;584(11):2485-90. Epub 2010 Apr 29. PMID: 20434445

Curcumin inhibits hepatitis C virus replication.
FEBS Lett. 2009 Dec 17. PMID: 20026048

Curcumin inhibits histiocytoma tumor cells.
FEBS Lett. 1999 Aug 6;456(2):311-4. PMID: 10456330

Curcumin inhibits HIV-1 integrase activity.
Biochem Pharmacol. 1995 Apr 18;49(8):1165-70. PMID: 7748198

Curcumin inhibits human colon cancer cell growth.
Oncogene. 2006 Jan 12;25(2):278-87. PMID: 16170359

Curcumin inhibits human leukemia cells.
Biochim Biophys Acta. 1996 Nov 15;1317(2):95-100. PMID: 8950193

Curcumin inhibits human malignant astrocytoma cell lines.
J Neurooncol. 2005 Sep;74(2):105-11. PMID: 16193380

Curcumin inhibits human ovarian cancer cell migration.
Cancer Chemother Pharmacol. 2008 Oct;62(5):857-65. Epub 2008 Jan 23. PMID: 18214481

Curcumin inhibits human pancreatic cancer cell growth.
Cancer. 2002 Sep 15;95(6):1206-14. PMID: 12216086

Curcumin inhibits human pancreatic cancer cell growth.
Cancer. 2004 Nov 15;101(10):2351-62. PMID: 15476283

Curcumin inhibits Human T-cell leukemia virus type I (HTLV-I).
Cancer Sci. 2006 Apr;97(4):322-7. PMID: 16630125

Curcumin inhibits hypoxia induced proliferation and collagen I synthesis.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Jul;41(4):621-5. PMID: 20848782

Curcumin inhibits hypoxia-induced angiogenesis associated wtih tumor progression.
Oncol Rep. 2006 Jun;15(6):1557-62. PMID: 16685395

Curcumin inhibits IMP dehydrogenase, a target for anticancer and antiviral chemotherapy agents.
Biosci Biotechnol Biochem. 2010;74(1):185-7. Epub 2010 Jan 7. PMID: 20057137

Curcumin inhibits in vitro MCP-1 release from mouse pancreatic islets, indicating it may have anti-rejection properties.
Transplant Proc. 2006 Nov;38(9):3035-8. PMID: 17112893

Curcumin inhibits inflammation associated with secretion of inflammatory chemokines.
Food Chem Toxicol. 2010 Jan;48(1):47-52. Epub 2009 Sep 18. PMID: 19766691

Curcumin inhibits inflammation-induced bone resportion that is frequently associated with cancers such as metastatic breast cancer and multiple myeloma.
Ann Rheum Dis. 1995 Jun;54(6):491-3. PMID: 15128775

Curcumin inhibits inflammation.
Food Chem Toxicol. 2006 Dec;44(12):1989-96. Epub 2006 Jul 12. PMID: 7786295

Curcumin inhibits inflammatory processes associated with skin cancer promotion.
Carcinogenesis. 2003 Sep;24(9):1515-24. Epub 2003 Jul 4. PMID: 12844482

Curcumin inhibits integrin (alpha6beta4)-dependent breast cancer cell motility and invasion.
Cancer Prev Res (Phila). 2008 Oct;1(5):385-91. PMID: 19138983

Curcumin inhibits interferon-alpha induced NF-kappaB and COX-2 in human non-small cell lung cancer cells.
Biochem Biophys Res Commun. 2005 Aug 26;334(2):313-8. PMID: 16005433

Curcumin inhibits invasion and metastasis in colorectal cancer.
Biosci Rep. 2011 Jan 14;31(3):185-97. PMID: 20815812

Curcumin inhibits invasive ductal carcinoma of the breast in the cell model.
Chem Biol Interact. 2010 Feb 12;183(3):455-61. Epub 2009 Nov 26. PMID: 19944674

Curcumin inhibits ionizing radiation-induced proliferation of human neuroblastoma cells.
Gynecol Endocrinol. 2010 Feb 23. Epub 2010 Feb 23. PMID: 21236599

Curcumin inhibits keloid formation in fibroblasts.
Arch Dermatol Res. 2010 Dec;302(10):717-24. Epub 2010 Aug 18. PMID: 20717830

Curcumin inhibits LDL cholesterol induced hepatic stellate cell activation associated with fatty liver and liver fibrosis.
Endocrinology. 2009 Dec;150(12):5384-94. Epub 2009 Oct 6. PMID: 19808779

Curcumin inhibits leiomyoma (fibroid) cell proliferation and fibronection expression.
Fertil Steril. 2009 May;91(5 Suppl):2177-84. Epub 2008 Jun 13. PMID: 18555241

Curcumin inhibits leptin-induced hepatic stellate cell activation.
Br J Pharmacol. 2010 Nov;161(5):1137-49. PMID: 20977462

Curcumin inhibits leukemia cell proliferation.
J Surg Res. 2010 Aug 6. Epub 2010 Aug 6. PMID: 12938514

Curcumin inhibits leukemia cell proliferation.
Acta Pharmacol Sin. 2003 Nov;24(11):1155-60. PMID: 14627502

Curcumin inhibits ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation associated with tumor cell growth.
Carcinogenesis. 1995 Aug;16(8):1741-5. PMID: 7634398

Curcumin inhibits lipid peroxidation and protein oxidation in rat liver mitochondria.
Biochim Biophys Acta. 2006 Jan;1760(1):70-7. Epub 2005 Oct 3. PMID: 16236451

Curcumin inhibits lipopolysaccharide-activated primary microglia.
Int Rev Neurobiol. 2009;88:297-334. PMID: 16934299

Curcumin inhibits lipopolysaccharide-induced inflammation.
Int Immunopharmacol. 2010 Jul;10(7):760-8. Epub 2010 Apr 22. PMID: 20399909

Curcumin inhibits lipoxygenase, indicating it possesses anti-inflammatory and anti-cancer properties.
Int J Mol Med. 2000 Nov;6(5):521-6. PMID: 11029517

Curcumin inhibits liver cancer cell gowth.
Zhonghua Gan Zang Bing Za Zhi. 2002 Dec;10(6):449-51. PMID: 12502450

Curcumin inhibits liver cancer cell invasiveness.
Comp Biochem Physiol B Biochem Mol Biol. 2000 Oct;127(2):213-22. PMID: 9663426

Curcumin inhibits liver fibrogenesis.
Int Immunopharmacol. 2005 Mar;5(3):555-69. PMID: 15683851

Curcumin inhibits liver tumor angiogenesis and growth.
Clin Hemorheol Microcirc. 2006;34(1-2):109-15. PMID: 16543625

Curcumin inhibits lung cancer by inducing programmed cell death and cell cycle arrest.
Cancer Lett. 2008 Dec 8;272(1):77-90. Epub 2008 Aug 12. PMID: 18701210

Curcumin inhibits lung cancer cells.
Mol Biol Rep. 2010 Mar;37(3):1627-32. Epub 2009 May 15. PMID: 19444642

Curcumin inhibits mantle cell lymphoma through a number of pathways.
Biochem Pharmacol. 2005 Sep 1;70(5):700-13. PMID: 16023083

Curcumin inhibits melanoma proliferation by arresting growth and induces programmed cell death.
Melanoma Res. 2004 Jun;14(3):165-71. PMID: 15179184

Curcumin inhibits metastatic breast cancer cells.
Front Oncol. 2012 ;2:161. Epub 2012 Nov 15. PMID: 23162792

Curcumin inhibits metastatic melanoma cells.
Cancer Lett. 2004 Aug 10;211(2):235-42. PMID: 15219947

Curcumin inhibits metastatic progression of breast cancer cells.
Mol Biol Rep. 2011 Sep 24. Epub 2011 Sep 24. PMID: 21947854

Curcumin inhibits migration and invasion of hepatic stellate cells by reducing MMP-2 expression and activity
Zhonghua Gan Zang Bing Za Zhi. 2009 Nov;17(11):835-8. PMID: 19958643

Curcumin inhibits multi drug resistance associated protein (MRP1) in retinoblastoma cells.
Bioinformation. 2012 ;8(1):13-9. Epub 2012 Jan 6. PMID: 22359429

Curcumin inhibits multi-drug resistance gene expression in human leukemic cells.
Arch Pharm Res. 2006 Oct;29(10):866-73. PMID: 17121181

Curcumin inhibits multi-drug resistant leukemia cells.
Mol Cell Biochem. 2012 Jan ;360(1-2):253-60. Epub 2011 Sep 22. PMID: 21938404

Curcumin inhibits multi-drug resistant pancreatic cancer.
Cancer Chemother Pharmacol. 2010 Nov 30. Epub 2010 Nov 30. PMID: 21116627

Curcumin inhibits murine neuroblastoma cells.
Neuro Endocrinol Lett. 2007 Apr;28(2):204-12. PMID: 17435663

Curcumin inhibits neuroglial cell proliferation and growth associated with neurodegenerative diseases.
Neuro Endocrinol Lett. 2003 Dec;24(6):469-73. PMID: 15073579

Curcumin inhibits nicotine-induced toxicity.
J Med Food. 2004;7(4):467-71. PMID: 15671691

Curcumin inhibits osteoclastogenesis, indicating its potential benefit in preventing and/or attenuating osteoporosis.
Mol Cells. 2008 Nov 30;26(5):486-9. PMID: 18719352

Curcumin inhibits ox-LDL stimulated vascular smooth muscle cell proliferation associated with arteriosclerosis.
Zhongguo Zhong Yao Za Zhi. 2006 Mar;31(6):500-3. PMID: 16722385

Curcumin inhibits ox-LDL-induced cholesterol accumulation associated with atherosclerosis.
Appl Environ Microbiol. 2008 Jul;74(14):4564-6. Epub 2008 May 23. PMID: 18430363

Curcumin inhibits pancreatic cancer cell and tumor growth.
J Biol Chem. 2010 Aug 13;285(33):25332-44. Epub 2010 Jun 9. PMID: 20538607

Curcumin inhibits pancreatic cancer cell growth and acts as a chemosensitizing agent.
Mol Pharmacol. 2009 Jul;76(1):81-90. Epub 2009 Apr 24. PMID: 19395473

Curcumin inhibits pancreatic cancer cell growth.
Cancer. 2006 Jun 1;106(11):2503-13. PMID: 16628653

Curcumin inhibits pancreatic cancer cell proliferation.
Eur J Cancer. 2009 Mar;45(5):874-80. Epub 2009 Feb 3. PMID: 19196508

Curcumin inhibits pancreatic cancer cells.
Am J Clin Nutr. 2010 Jan 13. Epub 2010 Jan 13. PMID: 20121547

Curcumin inhibits pathological processes initiated by Helicobacter pylori.
Biochem Biophys Res Commun. 2004 Apr 16;316(4):1065-72. PMID: 15044093

Curcumin inhibits phosphalipase D activity, indicating its potential role as an anti-inflammatory and anti-carcinogenic.
FEBS Lett. 1997 Nov 10;417(2):196-8. PMID: 9395294

Curcumin inhibits programmed cell death in breast cancer cells.
J Biol Chem. 2005 May 20;280(20):20059-68. Epub 2005 Feb 28. PMID: 15738001

Curcumin inhibits proliferation of multiple myeloma cells.
J Immunol. 2003 Oct 1;171(7):3863-71. PMID: 14500688

Curcumin inhibits prostate cancer cells.
Int J Cardiol. 1995 May;49(3):191-9. PMID: 12682902

Curcumin inhibits PSA expression in prostate cancer cell lines.
Yao Xue Xue Bao. 2005 Sep;40(9):800-3. PMID: 16342680

Curcumin inhibits PSA gene expression in prostate cancer cells.
J Androl. 2008 Nov-Dec;29(6):661-8. Epub 2008 Jul 31. PMID: 18676361

Curcumin inhibits ral squamous cell carcinoma cells.
Trop Med Int Health. 2010 Oct;15(10):1148-55. Epub 2010 Aug 17. PMID: 12359752

Curcumin inhibits Rift Valley Fever virus replication in human cells.
J Biol Chem. 2012 Jul 30. Epub 2012 Jul 30. PMID: 22847000

Curcumin inhibits telomerase activity and induces programmed cell death in cancer cells.
Mutat Res. 2006 Apr 11;596(1-2):81-90. Epub 2006 Jan 30. PMID: 16445949

Curcumin inhibits telomerase activity in breast ancer cells.
J Urol. 2011 Feb;185(2):719-24. Epub 2010 Dec 18. PMID: 12104041

Curcumin inhibits telomerase activity in human cancer cell lines.
Int J Mol Med. 2006 Aug;18(2):227-31. PMID: 16820928

Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells.
J Cell Biochem. 2012 Nov 28. Epub 2012 Nov 28. PMID: 23192708

Curcumin inhibits telomerase expression associated with tumorigensis.
Cancer Lett. 2010 Apr 1;290(1):76-86. Epub 2009 Sep 13. PMID: 19751963

Curcumin inhibits the activation of NF-kappaB associated with cancer progression.
Bioorg Med Chem. 2006 Apr 1;14(7):2450-61. Epub 2005 Dec 7. PMID: 16338138

Curcumin inhibits the formation of capillary-like tubes by rat lymphatic endothelial cells.
Cancer Lett. 2007 Jun 28;251(2):288-95. Epub 2007 Jan 2. PMID: 17197075

Curcumin inhibits the growth and induces programmed cell death in B cell lymphoma cells.
Clin Immunol. 1999 Nov;93(2):152-61. PMID: 10527691

Curcumin inhibits the growth of breast cancer through the manipulation of the arachidonate metabolism.
BMC Cancer. 2007;7:138. Epub 2007 Jul 25. PMID: 17651499

Curcumin inhibits the growth of human colon cancer cells.
Korean J Gastroenterol. 2005 Apr;45(4):277-84. PMID: 15843753

Curcumin inhibits the growth of human gastric cancer cells and shows synergistm with 5-fluorouracil.
J Med Food. 2004;7(2):117-21. PMID: 15298755

Curcumin inhibits the growth of ovary cancer cells.
J Clin Psychiatry. 2007;68 Suppl 10:4-7. PMID: 12520734

Curcumin inhibits the invasion and induces programmed cell death in human breast cancer cells.
Arch Pharm Res. 2001 Aug;24(4):349-54. PMID: 11534770

Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells.
Int J Cancer. 2006 Aug 15;119(4):757-64. PMID: 16550606

Curcumin inhibits the migration and invasion of human and lung cancer cells.
Cancer Lett. 2009 Nov 28;285(2):127-33. Epub 2009 May 23. PMID: 19477063

Curcumin inhibits the proliferation and induces programmed cell death of hepatic stellate cells.
Braz J Med Biol Res. 2009 Dec;42(12):1173-8. Epub 2009 Nov 13. PMID: 19918672

Curcumin inhibits the proliferation and migration of breast cancer cells.
Int J Mol Med. 2009 Apr;23(4):469-75. PMID: 19288022

Curcumin inhibits the proliferation of Burkitt cancer cells.
J Huazhong Univ Sci Technolog Med Sci. 2006;26(2):199-201, 210. PMID: 16850746

Curcumin inhibits the proliferation of colonic cancer cells.
Zhonghua Nei Ke Za Zhi. 2009 Sep;48(9):760-3. PMID: 20079215

Curcumin inhibits the proliferation of human liver cancer cells.
Int J Mol Med. 2010 Nov;26(5):673-8. PMID: 20878089

Curcumin inhibits the proliferation of leukemia cells.
Hunan Yi Ke Da Xue Xue Bao. 2000 Jun 28;25(3):216-8. PMID: 12212145

Curcumin inhibits the proliferation of vascular smooth muscle cells, indicating its value in cardiovascular diseases.
Biochem Biophys Res Commun. 2009 Feb 6;379(2):277-82. Epub 2008 Dec 25. PMID: 19101502

Curcumin inhibits the survival of multiple myeloma cells.
Blood. 2004 Apr 15;103(8):3175-84. Epub 2003 Dec 18. PMID: 15070700

Curcumin inhibits TNF and VCAM mediated inflammatory processes.
Biochem Pharmacol. 1998 Mar 15;55(6):775-83. PMID: 9586949

Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma.
J Clin Invest. 2009 May;119(5):1322-34. doi: 10.1172/JCI37385. Epub 2009 Apr 20. PMID: 17545551

Curcumin inhibits tyrosine kinase activity associated breast cancer cell promotion.
Clin Cancer Res. 1999 Jul;5(7):1884-91. PMID: 10430096

Curcumin inhibits ultraviolet light induced HIV gene expression.
Mol Cell Biochem. 2003 Dec;254(1-2):289-97. PMID: 14674708

Curcumin inhibits up-regulation of tumor necrosis factor alpha and reverses experimentally induced insulin resistance in adipocytes.
Biomed Environ Sci. 2009 Feb;22(1):32-9. PMID: 19462685

Curcumin inhibits uterine leiomyoma cell proliferation.
Gynecol Endocrinol. 2010 Jul 30. Epub 2010 Jul 30. PMID: 20672906

Curcumin inhibits UV radiation mutagenesis and SOS gene induction.
Ann Oncol. 2000 Dec;11(12):1537-43. PMID: 7477054

Curcumin inhibits xanthine oxidase.
Nutrition. 2006 Jun;22(6):593-9. PMID: 19800788

Curcumin is a histone deacetylase inhibitor.
Biochem Pharmacol. 2005 Apr 15;69(8):1205-13. PMID: 15794941

Curcumin is a nitric oxide scavenger.
Gynecol Oncol. 2004 Sep;94(3):760-8. PMID: 9120760

Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase.
FEBS Lett. 1994 Mar 14;341(1):19-22. PMID: 7511111

Curcumin is a potent inhibitor of glutathione S-transferase activity in human melanoma cells.
Chem Biol Interact. 1996 Oct 21;102(2):117-32. PMID: 8950226

Curcumin is a potent radiosensitizer and may act by overcoming the effects of radiation-induced NFkappaB mediated pro-survival gene expression in neuroblastoma.
Cancer Biol Ther. 2008 Apr;7(4):569-76. Epub 2008 Jan 7. PMID: 18305409

Curcumin is a potential candidate for prevention and treatment of hepatic fibrosis.
Biochem J. 2004 Nov 15;384(Pt 1):149-57. PMID: 15320868

Curcumin is a potential candidate for treatment of tubulointerstitial fibrosis.
Am J Nephrol. 2010;31(4):332-41. Epub 2010 Feb 17. PMID: 20160437

Curcumin is a potential inhibitor of human laryngeal squamous carcinoma cell invasion and metastasis.
J Am Coll Nutr. 2007 Dec;26(6):704S-12S. PMID: 17341208

Curcumin is a potentially promising compound for the treatment of Adult T-cell leukemia.
Leuk Res. 2006 Mar;30(3):313-21. Epub 2005 Sep 12. PMID: 16157375

Curcumin is a promising anticandidal of clinical interest.
Can J Microbiol. 2011 Mar;57(3):204-10. PMID: 21358761

Curcumin is a radiosensitizer of human cervical tumor cells.
Mol Pharmacol. 2008 May;73(5):1491-501. Epub 2008 Feb 5. PMID: 18252805

Curcumin is a radiosensitizer of squamous cell carcinoma cells.
Otolaryngol Head Neck Surg. 2005 Feb;132(2):317-21. PMID: 15692547

Curcumin is an inhibitor of calcium/calmodulin dependent protein kinase II.
Bioorg Med Chem. 2012 Oct 15 ;20(20):6040-7. Epub 2012 Aug 30. PMID: 22989913

Curcumin is an inhibitor of cancer.
J Am Coll Nutr. 1992 Apr;11(2):192-8. PMID: 1578097

Curcumin is an inhibitor of p300 histone acetylatransferase capable of blocking prostate cancer cells.
Med Chem. 2006 Mar;2(2):169-74. PMID: 16787365

Curcumin is an iron chelator. - Article 1.
Free Radic Biol Med. 2006 Apr 1;40(7):1152-60. PMID: 16545682

Curcumin is an iron chelator. - Article 2.
J Eur Acad Dermatol Venereol. 2004 Nov;18(6):649-53. PMID: 18815282

Curcumin is beneficial for improving Type 2 diabetes complications and assists in preventing oxidative stress and inflammation.
Br J Pharmacol. 2012 Mar 27. Epub 2012 Mar 27. PMID: 22452372

Curcumin is capable of inducing programmed cell death in gastric cancer cells.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2011 Nov ;27(11):1227-30. PMID: 22078453

Curcumin is cytotoxic to cervical cancer cells.
Mol Cell Biochem. 2009 May;325(1-2):107-19. Epub 2009 Feb 4. PMID: 19191010

Curcumin is effective in blocking lipopolysaccharide-induced loss of muscle mass.
J Cell Biochem. 2007 Mar 1;100(4):960-9. PMID: 17131360

Curcumin may act as a chemosensitizer in multi-drug resistant cancer.
Zhongguo Zhong Yao Za Zhi. 2010 Sep;35(18):2460-3. PMID: 21141501

Curcumin may act as a chemosensitizing agent in multidrug resistant cancer cells.
Biochem Pharmacol. 2002 Aug 15;64(4):573-82. PMID: 12167476

Curcumin may act as a chemosensitizing agent.
Adv Exp Med Biol. 2007;595:269-300. PMID: 17569216

Curcumin may act as a photosensitizer and chemotherapeutic agent in nasopharyngeal carcinoma.
J Environ Pathol Toxicol Oncol. 2006;25(1-2):205-15. PMID: 16566718

Curcumin may attenuate diabetic complications.
FEBS Lett. 2009 Nov 19;583(22):3637-42. Epub 2009 Oct 20. PMID: 19850041

Curcumin may attenuate lead and cadmium-induce neurotoxicity.
Anesth Analg. 2001 Oct;93(4):912-6. PMID: 14729307

Curcumin may be a potential radiosensitizing agent for enhanced antiangiogenic effect in colorectal cancer radiation therapy.
Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G865-77. Epub 2010 Mar 18. PMID: 20299603

Curcumin may be a powerful candidate for developing preventive agents for cancer metastasis.
Oncol Rep. 2010 Mar;23(3):665-70. PMID: 20127004

Curcumin may be applied as an effective and novel sunscreen drug for the protection of photoinflammation.
Exp Mol Med. 2005 Jun 30;37(3):186-92. PMID: 16000872

Curcumin may be effective against oxidative bowel damages induced in IBD by imbalanced gut immune response.
Int Immunopharmacol. 2012 Jan ;12(1):302-11. Epub 2011 Oct 29. PMID: 22036766

Curcumin may be used as a chemosensitizer to make the retinoblastoma cells more sensitive to the effects of chemotherapy.
Curr Eye Res. 2009 Oct;34(10):845-51. PMID: 19895312

Curcumin may be used as a novel intravaginal spermicidal agent for contraception and HIV prevention.
Contraception. 2003 Sep;68(3):219-23. PMID: 14561543

Curcumin may be useful to prevent changes of atherosclerosis and post-angioplasty restenosis.
Br J Pharmacol. 1998 Jul;124(6):1029-40. PMID: 9720770

Curcumin may block brain tumor formation.
Brain Res. 2009 Feb 10. Epub 2009 Feb 10. PMID: 19368804

Curcumin may contribute to accelerated wound healing.
Pathophysiol Haemost Thromb. 2010 Nov 12. Epub 2010 Nov 12. PMID: 21071923

Curcumin may contribute to overcoming chemoresistance of FOLFOX.-surviving colon cancer cells.
Vet Med (Praha). 1989 Aug;34(8):467-74. PMID: 20332435

Curcumin may decrease the progression of glomerulosclerosis.
Zhonghua Er Ke Za Zhi. 2003 Nov;41(11):822-6. PMID: 14728887

Curcumin may down-regulate genes associated with cancer progression in prostate cancer.
Cancer Biol Ther. 2008 Sep;7(9):1427-35. Epub 2008 Sep 4. PMID: 18719366

Curcumin may enhance the chemotherapeuic efficacy of all-trans retinoic acid against human promyelocytic leukemia cells.
Oncol Res. 1997;9(1):19-29. PMID: 9112257

Curcumin may facilitate chemoprevention via direct binding to, and activation of, vitamin D receptor (VDR).
J Nutr Biochem. 2010 Dec;21(12):1153-61. Epub 2010 Feb 12. PMID: 20153625

Curcumin may have a role to play in modulating pathological scar formation.
J Cell Mol Med. 2009 Apr;13(4):712-25. Epub 2008 Apr 10. PMID: 18410527

Curcumin may have a therapeutic role in the treatment of cystic fibrosis.
Nutr Cancer. 1992;18(2):181-9. PMID: 16424149

Curcumin may have a therapeutic role in hyperplastic scars.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Dec;29(12):1100-3. PMID: 20214332

Curcumin may have a therapeutic role in reducing diabetic complications.
J Biosci. 2003 Dec;28(6):715-21. PMID: 14660871

Curcumin may have a therapeutic role in Th1-mediated immune diseases.
Br J Pharmacol. 1999 Sep;128(2):380-4. PMID: 10510448

Curcumin may have a therapeutic role in the treatment of autoimmune diseases.
Eur J Pharmacol. 2011 Jan 10;650(1):451-7. Epub 2010 Oct 13. PMID: 20950605

Curcumin may have a therapeutic role in the treatment of osteoarthritis.
Osteoarthritis Cartilage. 2010 Feb;18(2):141-9. Epub 2009 Oct 8. PMID: 19836480

Curcumin may have an anti-malarial effect by inducing cell death in infected erythrocytes.
Cell Physiol Biochem. 2009;24(3-4):133-40. Epub 2009 Aug 3. PMID: 19710527

Curcumin may have anti-aging properties.
Mol Nutr Food Res. 2010 Oct 11. Epub 2010 Oct 11. PMID: 20938987

Curcumin may have anti-malarial properties.
Bone. 2010 Nov;47(5):926-37. Epub 2010 Aug 7. PMID: 19329310

Curcumin may have anti-obesity properties.
J Nutr Biochem. 2010 Dec 27. Epub 2010 Dec 27. PMID: 21189228

Curcumin may have anti-tumor properties in cervical cancer.
Phytother Res. 2008 Sep 23. PMID: 19058955

Curcumin may have chemosensitizing properties in the treatment of human ovarian cancer.
Cell Prolif. 2009 Apr;42(2):195-206. Epub 2009 Feb 18. PMID: 19236381

Curcumin may have inhibitory activity against HIV-1 protease and integrase.
Am J Clin Nutr. 1995 Mar;61(3):585-9. PMID: 15950462

Curcumin may have positive epigenetic effects in high prostate cancer.
AAPS J. 2011 Dec ;13(4):606-14. Epub 2011 Sep 22. PMID: 21938566

Curcumin may have potential therapeutic uses in the prevention and treatment of endometriosis.
Phytother Res. 2011 Dec 20. Epub 2011 Dec 20. PMID: 22183741

Curcumin may have therapeutic potential for bladder cancer patients via anti-inflammatory, antioxidant and anti-carcinogenic activities.
Oncol Rep. 2006 May;15(5):1225-31. PMID: 16596191

Curcumin may have therapeutic value against amyloid diseases.
Biol Chem. 2009 Oct;390(10):1057-61. PMID: 19558331

Curcumin may have therapeutic value in allergic diseases.
J Allergy Clin Immunol. 2008 May;121(5):1225-31. Epub 2008 Apr 18. PMID: 18394691

Curcumin may have therapeutic value in Alzheimer disease.
Brain Res. 2010 Nov 18;1361:115-23. Epub 2010 Sep 16. PMID: 20840842

Curcumin may have therapeutic value in cancer as a proteasome inhibitor.
Int J Mol Med. 2010 Oct;26(4):447-55. PMID: 20818481

Curcumin may have therapeutic value in cardiomyopathies.
J Cardiovasc Pharmacol. 2010 Feb;55(2):176-83. PMID: 19935077

Curcumin may have therapeutic value in chronic myelocytic leukemia (CML).
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2004 Oct;12(5):572-6. PMID: 15498113

Curcumin may have therapeutic value in cystic fibrosis.
Trends Mol Med. 2004 Oct;10(10):473-5. PMID: 15464445

Curcumin may have therapeutic value in Hemolytic-Uremic Syndrome.
Biol Pharm Bull. 2006 Jul;29(7):1470-5. PMID: 16819191

Curcumin may have therapeutic value in HIV infection.
Mol Nutr Food Res. 2010 Feb 19. Epub 2010 Feb 19. PMID: 15383533

Curcumin may have therapeutic value in inflammatory conditions of the central nervous system.
J Neuroinflammation. 2005 Feb 25;2(1):8. Epub 2005 Feb 25. PMID: 15733321

Curcumin may have therapeutic value in inhibiting B-Cell over-activity.
Phytomedicine. 2009 Oct;16(10):982-8. Epub 2009 Mar 20. PMID: 19303754

Curcumin may have therapeutic value in polycystic kidney disease.
Eur J Pharmacol. 2011 Mar 1;654(1):92-9. Epub 2010 Dec 24. PMID: 21187084

Curcumin may have therapeutic value in the prevention of transplant-associated organ injury and rejection.
Biochem Biophys Res Commun. 2003 Sep 5;308(4):950-5. PMID: 12927811

Curcumin may have therapeutic value in the treatment of endometriosis.
Indian J Biochem Biophys. 2009 Feb;46(1):59-65. PMID: 19374255

Curcumin may have therapeutic value in treating human chronic myelogenous leukemia due to its ability to regulate NF-kappB genes and pathways.
Ann N Y Acad Sci. 2009 Aug;1171:436-47. PMID: 19723087

Curcumin may have therapeutic value in treating human liposarcoma.
Phytomedicine. 2005 Nov;12(10):715-22. PMID: 21282356

Curcumin may have therapeutic value in treating hyaline membrane disease.
Life Sci. 2001 Dec 7;70(3):253-67. PMID: 12005259

Curcumin may have therapeutic value in Wilson disease.
Hepatology. 2009 Dec;50(6):1783-95. PMID: 19937698

Curcumin may improve outcome in chemotherapy-refractory Natural killer/T-cell lymphoma (NKTL).
Br J Haematol. 2005 Oct;131(1):59-66. PMID: 16173963

Curcumin may inhibit breast cancer cell proliferation through down-regulating the NFkappaB inducing genes.
Phytomedicine. 2009 Oct;16(10):916-22. Epub 2009 Jun 12. PMID: 19524420

Curcumin may inhibit Coxsackievirus
J Virol. 2007 Apr;81(7):3142-50. Epub 2007 Jan 17. PMID:17229707

Curcumin may inhibit oxidative stress including LDL cholesterol oxidation.
J Enzyme Inhib Med Chem. 2010 Oct;25(5):720-9. PMID: 20163327

Curcumin may offer a therapeutic advantage in the clinical management of refractory bladder cancer.
Cancer Prev Res (Phila). 2011 Oct ;4(10):1698-709. Epub 2011 Aug 11. PMID: 21836020

Curcumin may overcome resistance in leukemia cells.
Int J Cancer. 2006 Oct 15;119(8):1811-8. PMID: 16721786

Curcumin may play a protective effect in primary cultured rat prefrontal cortical neurons against iAbeta-induced cytotoxicity.
Neurosci Lett. 2010 Aug 9;480(1):21-4. PMID: 20638958

Curcumin may play a protective role against oxidative stress in islet transplantation outcomes.
Pancreas. 2009 May;38(4):454-60. PMID: 19188863

Curcumin may play a role in suppressing hepatic fibrinogenesis.
Lab Invest. 2008 May;88(5):529-40. Epub 2008 Mar 10. PMID: 18332871

Curcumin may play a therapeutic role in diseases of the bone associated with osteoclastogenesis and bone lysis.
J Cancer Res Clin Oncol. 2009 Feb;135(2):173-9. Epub 2008 Sep 3. PMID: 18766375

Curcumin may play a therapeutic role in heart failure.
J Food Sci. 2007 Oct;72(8):S612-7. PMID: 20467147

Curcumin may prevent and treat muscle wasting.
Nutrition. 2009 Feb;25(2):125-9. Epub 2008 Nov 22. PMID: 19028079

Curcumin may prevent ferric nitrilotriacetate (Fe-NTA) induced toxicity and cancer.
J Cutan Pathol. 2009 Oct;36(10):1053-62. Epub 2009 Jan 27. PMID: 12616605

Curcumin may protect against amyloid-beta-stimulated inflammation associated wtih Alzheimer disease.
J Alzheimers Dis. 2010;20(4):1189-99. PMID: 20413894

Curcumin may provide an ideal therapeutic agent for patients with Hodgkin's lymphoma which does not have the side effects associated with multi-drug chemotherapy.
Int J Cancer. 2008 Jul 1;123(1):56-65. PMID: 18386790

Curcumin may provide an ideal therapy for metabolic syndrome.
Biofactors. 2012 Dec 13. Epub 2012 Dec 13. PMID: 23239418

Curcumin may provide an ideal therapy to down-regulate epidermal growth factor receptor activity.
J Mol Recognit. 2012 Nov ;25(11):623-9. PMID: 23108622

Curcumin may reduce carcinogenesis by binding to (and inhibiting) lipoxygenase.
Int J Mol Med. 2003 Jul;12(1):17-24. PMID: 12792803

Curcumin may reduce inflammation in the pancreas.
Mol Biol Rep. 2009 Nov;36(8):2329-32. Epub 2009 Jan 21. PMID: 19156536

Curcumin may represent a novel therapeutic agent targeting endothelial activation in inflammatory bowel disease.
Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G259-68. Epub 2009 Jun 11. PMID: 19520742

Curcumin may sensitize cancer cells to chemotherapy.
Mol Cancer Ther. 2006 Apr;5(4):952-61. PMID: 16648566

Curcumin may slow aging.
Curr Pharm Des. 2010;16(7):884-92. PMID: 20388102

Curcumin may support the regeneration of articular cartilage.
Arthritis Res Ther. 2010;12(4):R127. Epub 2010 Jul 1. PMID: 20594343

Curcumin may work synergistically with antifungal drugs to reverse multidrug resistance in Candida cells.
Antimicrob Agents Chemother. 2009 Aug;53(8):3256-65. Epub 2009 May 26. PMID: 19470507

Curcumin may work synergistically with taxane chemotherapy for hormone-refractory prostate cancer treatment.
Nutr Cancer. 2010;62(2):148-53. PMID: 20099188

Curcumin might have therapeutic potential for treating dry eye disease.
Exp Eye Res. 2010 Mar;90(3):437-43. Epub 2009 Dec 23. PMID: 20026325

Curcumin might provide a novel therapeutic strategy for treating gliomas.
Biochem Biophys Res Commun. 2005 Nov 18;337(2):510-6. Epub 2005 Sep 21. PMID: 16198311

Curcumin modulates cell cycle in leukemia cells and enhances programmed cell death.
J Tongji Med Univ. 2000;20(2):123-5. PMID: 12845723

Curcumin opens cystic fibrosis transmembrane conductance regulator channels by a novel mechanism, indicating it may have therapeutic value in the condition.
J Biol Chem. 2007 Feb 16;282(7):4533-44. Epub 2006 Dec 18. PMID: 17178710

Curcumin participates in reversing multi-drug resistance in cancer cells.
Zhonghua Xue Ye Xue Za Zhi. 2006 Apr;27(4):254-8. PMID: 16875558

Curcumin potentiates antitumor activity of l-asparaginase in acute lymphoblastic leukemia.
Leuk Lymphoma. 2012 Jan 25. Epub 2012 Jan 25. PMID: 22185211

Curcumin potentiates the apoptotic effects of chemotherapeutic agents in drug resistant human bladder cancer cells.
Mol Cancer Ther. 2007 Mar;6(3):1022-30. PMID: 17363495

Curcumin potentiates the pro-apoptotic effects of sulindac sulfone in colorectal cancer.
Expert Opin Investig Drugs. 2010 Apr;19 Suppl 1:S117-24. PMID: 20374023

Curcumin potently induces programmed cell death in colon cancer cells
Br J Nutr. 2005 Jun;93(6):835-44. PMID: 19723094

Curcumin pretreatment may have clinical potential in hepatic transplantation.
Transplantation. 2006 Feb 27;81(4):623-6. PMID: 16495813

Curcumin prevents acrylamide-induced DNA damage in liver cells.
Wei Sheng Yan Jiu. 2009 Jul;38(4):392-5. PMID: 19689063

Curcumin prevents benzo[a]pyrene-induced DNA adduct formation.
Cancer Lett. 1995 Sep 4;96(1):71-80. PMID: 7553610

Curcumin prevents chemically-induced inflammation in gastrointestinal lines associated with cancer promotion.
J Invest Dermatol. 2009 Feb;129(2):468-75. Epub 2008 Aug 14. PMID: 10190560

Curcumin prevents cholesterol oxidation, indicating its therapeutic value in attenuating atherosclerosis and lesion formation.
Prostaglandins Other Lipid Mediat. 2009 Nov;90(1-2):13-20. Epub 2009 Jun 21. PMID: 19549571

Curcumin prevents DNA damage associated with benzo[a]pyrene exposure.
Mutat Res. 2004 Feb 14;557(2):203-13. PMID: 14729375

Curcumin prevents dopaminergic neuronal death.
Rejuvenation Res. 2010 Feb;13(1):55-64. PMID: 20230279

Curcumin prevents Epstein-Barr virus induced Post-Transplant Lymphoproliferative disorder (PTLD).
Am Surg. 1998 Jan;64(1):47-51; discussion 51-2. PMID: 9457037

Curcumin prevents homocysteine-induced endothelial dysfunction in porcine coronary arteries.
Biol Pharm Bull. 2001 Sep;24(9):1091-2. PMID: 15622377

Curcumin prevents human dendritic cell response to immune stimulants, indicating it may have value as an immunosuppresant.
Biochem Biophys Res Commun. 2008 Sep 26;374(3):431-6. Epub 2008 Jul 17. PMID: 18639521

Curcumin prevents nitrite-induced methemoglobin formation.
FEBS Lett. 1992 Apr 20;301(2):195-6. PMID: 1314741

Curcumin prevents progestin-induced breast cancer cell promotion.
Menopause. 2008 May-Jun;15(3):570-4. PMID: 18467956

Curcumin prevents the migration of nasopharyngeal cancer cells.
Anticancer Res. 2010 Jul;30(7):2851-6. PMID: 20683022

Curcumin prevents TNF-alpha induced endothelial dysfunction.
Thromb Res. 2005;115(5):417-26. Epub 2004 Nov 14. PMID: 15733976

Curcumin prevents tumor-induced T cell apoptosis.
Behav Brain Res. 2011 Mar 24. Epub 2011 Mar 24. PMID: 17392282

Curcumin promotes programmed cell death in multidrug-resistant human lung cancer cells.
Biochem Biophys Res Commun. 2010 Aug 13;399(1):1-6. Epub 2010 Jul 11. PMID: 20627087

Curcumin promotes programmed cell death in esophageal squamous carcinoma cell lines.
Ai Zheng. 2008 Jun;27(6):566-70. PMID: 18570726

Curcumin promotes programmed cell death in human lung adenocarcinoma cells.
J Sep Sci. 2009 Apr;32(7):955-64. PMID: 20878113

Curcumin promotes programmed cell death of cisplain-resistant human lung carcinoma cells.
Zhongguo Fei Ai Za Zhi. 2010 Apr;13(4):301-6. PMID: 20677554

Curcumin promotes programmed cell death, increases chemosensitivity, and inhibits nuclear factor kappaB in esophageal adenocarcinoma.
Transl Oncol. 2010 Apr;3(2):99-108. PMID: 20360934

Curcumin protects 6-hydroxydopamine (6-OHDA)-induced neuronal death associated with Parkinson disease.
Biochem Pharmacol. 2009 Jul 15;78(2):178-83. Epub 2009 Apr 8. PMID: 19464433

Curcumin protects against adverse changes associated with neuronal hypoxia.
Asia Pac J Clin Nutr. 2003;12(1):50-60. PMID: 18461445

Curcumin protects against beta-amyloid-induced toxicity.
Food Chem Toxicol. 2008 Aug;46(8):2881-7. Epub 2008 Jun 4. PMID: 18573304

Curcumin protects against cerebral ischemia-induced neuronal cell death.
J Neurosci Res. 2005 Oct 1;82(1):138-48. PMID: 16075466

Curcumin protects against chemically induced cell death.
Apoptosis. 2006 Jun;11(6):943-53. PMID: 16547587

Curcumin protects against chemically-induced cataract formation in rat lenses.
Am J Clin Nutr. 1996 Nov;64(5):761-6. PMID: 8901798

Curcumin protects against chemically-induced neuronal damage.
Acta Pharmacol Sin. 2004 Dec;25(12):1606-12. PMID: 15569404

Curcumin protects against chemically-induced Parkinsonism in a cell model.
Pharmacol Res. 2011 Jan 12. Epub 2011 Jan 12. PMID: 21237271

Curcumin protects against copper injury.
Psychiatry Res. 1999 Nov 29;88(3):227-32. PMID: 18082042

Curcumin protects against gastric ulcers by blocking H2 histamine receptors.
Biol Pharm Bull. 2005 Dec;28(12):2220-4. PMID: 16327153

Curcumin protects against glutamate excitotoxicity.
Brain Res. 2008 May 19;1210:84-91. Epub 2008 Apr 16. PMID: 18420184

Curcumin protects against hydrogen peroxide induced cytotoxicity.
Hum Exp Toxicol. 2010 May 20. Epub 2010 May 20. PMID: 20488840

Curcumin protects against methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells.
Acta Pharmacol Sin. 2006 Sep;27(9):1192-8. PMID: 16923340

Curcumin protects against mutagenic heterocyclic amines found in cooked food.
Indian J Exp Biol. 2002 Dec;40(12):1365-72. PMID: 12974398

Curcumin protects against smoke-induced DNA damage.
Metabolism. 2002 Jul;51(7):887-92. PMID: 1937145

Curcumin protects against staurosporine toxicity in rat neurons.
Neurosci Bull. 2012 Oct ;28(5):606-10. Epub 2012 Oct 3. PMID: 23054638

Curcumin protects cardiac cells against ischemia-reperfusion injury.
Free Radic Biol Med. 2008 Sep 15;45(6):839-46. Epub 2008 Jun 20. PMID: 18638545

Curcumin protects dopaminergic cells from Parkinson disease-associated 6-hydroxydopamine-induced neurotoxicity.
Neurosci Lett. 2011 Feb 11;489(3):192-6. Epub 2010 Dec 15. PMID: 21167259

Curcumin protects dopaminergic neuron against lipopolysaccharide induced neurotoxicity.
Neurochem Res. 2008 Oct;33(10):2044-53. Epub 2008 Mar 27. PMID: 18368483

Curcumin protects hepatic stellate cells against leptin-induced activation, indicating its therapeutic value in fatty and fibrotic liver conditions.
Endocrinology. 2010 Sep;151(9):4168-77. Epub 2010 Jul 21. PMID: 20660066

Curcumin protects the brain against drug-induced neurotoxicity, indicating it may have value in preventing neurological disorders such as Parkinson disease.
Antioxid Redox Signal. 2007 Mar;9(3):399-408. PMID: 17184173

Curcumin provides antioxidant and anti-inflammatory therapeutic benefits in the treatment of chronic inflammatory lung diseases.
Mol Nutr Food Res. 2008 Sep;52(9):987-94. PMID: 18327875

Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model.
BMC Neurosci. 2010;11:57. Epub 2010 Apr 30. PMID: 20433710

Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition.
J Cardiovasc Pharmacol. 2010 Apr;55(4):417-24. PMID: 20422739

Curcumin reduces chemo-resistance of melanoma cells to tamoxifen.
Cancer Biol Ther. 2011 Jan 29;11(2). Epub 2011 Jan 29. PMID: 21088500

Curcumin reduces cisplatin-induced neurotoxicity.
Neurotoxicology. 2012 Oct 2. Epub 2012 Oct 2. PMID: 23036615

Curcumin reduces DNA adduct formation in human lung cancer cells.
Toxicol In Vitro. 2003 Jun;17(3):323-33. PMID: 12781211

Curcumin reduces inflammation and carcinogensis associated with arachidonic acid metabolism.
J Nutr. 2009 Jul;139(7):1273-8. Epub 2009 May 20. PMID: 15073046

Curcumin reduces lipopolysaccharide-indced nitric oxide synthetase activity.
Int Immunopharmacol. 2011 Feb;11(2):179-86. Epub 2010 Nov 20. PMID: 21094287

Curcumin reduces multi-drug resistance in uterine cancer cells.
Oncol Rep. 2008 Oct;20(4):731-5. PMID: 18813811

Curcumin reduces NF-kappa B factor activation associated with anticancer drugs.
Endocr Relat Cancer. 2009 Dec;16(4):1339-50. Epub 2009 Sep 2. PMID: 12007574

Curcumin reduces the expression of malignancy-associated Bcl-2 in breast cancer cells.
Med Oncol. 2010 Dec;27(4):1114-8. Epub 2009 Nov 12. PMID: 19908170

Curcumin reduces the programmed cell death associated with toxic bile acids in liver injury during cholestasis.
Biochem Biophys Res Commun. 2006 Feb 17;340(3):800-6. Epub 2005 Dec 20. PMID: 16380075

Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells.
Liver Int. 2009 Jan;29(1):63-72. Epub 2008 May 19. PMID: 18492020

Curcumin restores corticosteroid function in monocytes exposed to oxidants, thus overcoming cortisone resistance.
Am J Respir Cell Mol Biol. 2008 Sep;39(3):312-23. Epub 2008 Apr 17. PMID: 18421014

Curcumin reverse multi-drug resistance in multiple myeloma cells.
Ann Hematol. 2010 Apr;89(4):399-404. Epub 2009 Sep 15. PMID: 19756599

Curcumin reverse multidrug resistance of osteosarcoma cells.
Wei Sheng Yan Jiu. 2011 Jan;40(1):103-6. PMID: 21434326

Curcumin reverses chemoresistance of human gastric cancer cells.
Oncol Rep. 2011 Aug 2. Epub 2011 Aug 2. PMID: 21811763

Curcumin reverses the multidrug resistance of a human multiple myeloma cell line.
Zhonghua Xue Ye Xue Za Zhi. 2009 Jan;30(1):33-7. PMID: 19563033

Curcumin selectively inhibits and induces programmed cell death in B-cell lymphoma cells.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 Nov;24(11):1003-6. PMID: 15609600

Curcumin selectively inhibits tumor cells.
Mol Cancer Ther. 2004 Sep;3(9):1101-8. PMID: 15367704

Curcumin selectively targets immortalized normal, leukoplakia, and malignant oral cells.
Cancer Prev Res (Phila). 2010 Mar;3(3):331-8. Epub 2010 Feb 9. PMID: 20145189

Curcumin sensitizes cervical cancer cells to curcumin-induced programmed cell death.
J Biol Chem. 2005 Feb 25;280(8):6301-8. Epub 2004 Dec 7. PMID: 15590651

Curcumin sensitizes lung cancer cells to cisplatin-induced programmed cell death.
Phytother Res. 1999 Jun;13(4):318-22. PMID: 19283527

Curcumin sensitizes prostate cancer cells to programmed cell death.
J Pharmacol Exp Ther. 2007 May;321(2):616-25. Epub 2007 Feb 8. PMID: 17289836

Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related programmed cell death.
Mol Cancer Ther. 2004 Jul;3(7):803-12. PMID: 15252141

Curcumin shows promising anticryptosporidial activity.
Parasitol Res. 2009 Oct;105(4):1155-61. Epub 2009 Jun 26. PMID: 19557435

Curcumin significantly inhibits the growth and induces programmed cell death in human ovarian cancer cell lines. - Article 1
Cell Biol Int. 2006 Mar;30(3):221-6. Epub 2005 Dec 22. PMID: 16376585

Curcumin significantly inhibits the growth and induces programmed cell death in human ovarian cancer cell lines. - Article 2
J Huazhong Univ Sci Technolog Med Sci. 2004;24(1):55-8. PMID: 15165116

Curcumin slows proliferation in the infant acute monocytic leukemia cell line.
Cell Physiol Biochem. 2011 ;28(6):1169-80. Epub 2011 Dec 16. PMID: 22179005

Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity.
J Immunotoxicol. 2007 Apr;4(2):85-96. PMID: 15582996

Curcumin stimulates glucose uptake in myotube (muscle) cells.
J Cell Physiol. 2010 Jun;223(3):771-8. PMID: 20205235

Curcumin stimulates programmed cell death in melanoma cells.
Apoptosis. 2008 Jul;13(7):904-14. PMID: 18493855

Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.
J Pharmacol Exp Ther. 2010 Oct;335(1):114-23. Epub 2010 Jul 6. PMID: 20605902

Curcumin supplementation by reducing vascular inflammation may prevent diabetic complications.
J Nutr Biochem. 2010 Jul 21. Epub 2010 Jul 21. PMID: 20655188

Curcumin supplementation may prevent the cellular dysfunction associated with diabetes.
Free Radic Biol Med. 2006 Jul 1;41(1):92-6. Epub 2006 Mar 30. PMID: 16781457

Curcumin suppresses breast cancer cells growth.
FEBS J. 2010 Aug;277(16):3437-48. Epub 2010 Jul 14. PMID: 20646066

Curcumin suppresses cigarette smoke-induced promotion of human non-small cell lung cancer cell growth.
Carcinogenesis. 2003 Jul;24(7):1269-79. Epub 2003 May 9. PMID: 12807725

Curcumin suppresses colon cancer cells.
World J Gastroenterol. 2009 Mar 21;15(11):1346-52. PMID: 19294764

Curcumin suppresses growth and chemoresistance of human glioblastoma cells.
J Neurochem. 2007 Jul;102(2):522-38. PMID: 17596214

Curcumin suppresses head and neck cancer cell growth.
Arch Otolaryngol Head Neck Surg. 2009 Feb;135(2):190-7. PMID: 19221248

Curcumin suppresses hepatic stellate cell genes, indicating its therapeutic value for hepatitic fibrosis.
Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G883-93. Epub 2005 Nov 23. PMID: 16306131

Curcumin suppresses HPV oncoproteins and HPV upregulation associated wtih benzo[a]pyrene exposure.
Mol Carcinog. 2011 Jan;50(1):47-57. PMID: 21061268

Curcumin suppresses human breast cancer cell growth.
Chem Biol Interact. 2009 Oct 7;181(2):263-71. Epub 2009 Jun 30. PMID: 19573523

Curcumin suppresses human promyelocytic leukemia cells.
J Biochem Mol Biol. 2002 May 31;35(3):337-42. PMID: 12297018

Curcumin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression associated with inflammation.
J Pharmacol Sci. 2004 Mar;94(3):325-8. PMID: 15037818

Curcumin suppresses melanogenesis in melanoma cells.
Int J Mol Med. 2010 Jul;26(1):101-6. PMID: 20514428

Curcumin suppresses mouse pituitary corticotroph tumor cells.
PLoS One. 2010;5(4):e9893. Epub 2010 Apr 13. PMID: 20405005

Curcumin suppresses oral carcinogenesis.
Int J Cancer. 2010 Jul 1;127(1):9-20. PMID: 20127863

Curcumin suppresses proliferation and induces programmed cell death in human multiple myeloma cells.
Blood. 2003 Feb 1;101(3):1053-62. Epub 2002 Sep 5. PMID: 12393461

Curcumin suppresses proliferation and invasion in human gastric cancer cells.
Cancer Biol Ther. 2009 Jul;8(14):1360-8. Epub 2009 Jul 13. PMID: 19448398

Curcumin suppresses protein kinase C and nuclear oncogene expression associated with cancer progression.
Arch Pharm Res. 2004 Jul;27(7):683-92. PMID: 15356994

Curcumin suppresses SV40-immortalized bladder cancer cells.
Anticancer Res. 2007 Mar-Apr;27(2):737-40. PMID: 17465196

Curcumin suppresses the growth and induces programmed cell death in bladder cancer cells, in vitro.
Zhong Yao Cai. 2004 Nov;27(11):848-50. PMID: 15810596

Curcumin suppresses the inflammatory response of brain microglial cells.
J Immunol. 2003 Dec 1;171(11):6072-9. PMID: 14634121

Curcumin suppresses transcription factor Egr-1.
Thromb Res. 2000 Feb 15;97(4):179-89. PMID: 10674404

Curcumin synergistically augments bcr/abl phosphorothioate antisense oligonucleotides to inhibit growth of chronic myelogenous leukemia cells.
Acta Pharmacol Sin. 2007 Jan;28(1):105-10. PMID: 17184589

Curcumin synergistically potentiates the anti-cancer effects of celecoxib in pancreatic cancer cells.
Biomed Pharmacother. 2005 Oct;59 Suppl 2:S276-80. PMID: 16507392

Curcumin synergizes the growth inhibitory properties of Indian toad skin-derived factor in colon cancer cells.
Phytother Res. 2007 Sep;21(9):895-7. PMID: 19331178

Curcumin synergizes with resveratrol to inhibit colon cancer.
J Endocrinol. 2003 Jan;176(1):163-8. PMID: 19838927

Curcumin targets the AKT-mTOR pathway for uterine leiomyosarcoma tumor growth suppression.
Int J Clin Oncol. 2013 May 11. Epub 2013 May 11. PMID: 23666561

Curcumin treatment protects rat retinal neurons against excitotoxicity.
Exp Brain Res. 2005 Dec;167(4):641-8. Epub 2005 Aug 3. PMID: 16078027

Curcumin work synergistically with a PI3K inhibitor to induce cell death in breast cancer cellis.
Biochem Biophys Res Commun. 2010 Apr 9;394(3):476-81. Epub 2010 Feb 6. PMID: 20138829

Curcumin works synergistically with antifungal drugs.
FEMS Yeast Res. 2010 Aug 1;10(5):570-8. Epub 2010 Apr 23. PMID: 20528949

Curcumin works synergistically with bortezomib in multiple myeloma.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2011 Jun ;19(3):684-8. PMID: 21729550

Curcumin works synergistically with celecoxib to potentiate a growth-inhibitory and pro-apoptotic in osteoarthritis synovial adherent cells.
Rheumatology (Oxford). 2006 Feb;45(2):171-7. Epub 2005 Oct 25. PMID: 16249246

Curcumin works synergistically with copper to damage leukemia cells.
Molecules. 2009;14(12):5328-38. Epub 2009 Dec 17. PMID: 20032896

Curcumin works synergistically with cyclophosmide to reverse multi-drug resistance of a human lymphoma cell line.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008 Aug;16(4):804-8. PMID: 18718065

Curcumin works synergistically with drugs as an anti-fibrotic agent in liver fibrosis.
Zhong Yao Cai. 2003 Nov;26(11):795-8. PMID: 14989060

Curcumin works synergistically with EGF-receptor protein to inhibit the growth of colon cancer cells.
Nutr Cancer. 2006;55(2):185-94. PMID: 17044774

Curcumin works synergistically with insulin on muscle cell glucose metabolism.
Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2366-73. Epub 2010 Jun 1. PMID: 20561944

Curcumin works synergistically with light to inhibit bacterial growth.
Arch Microbiol. 1989;151(2):183-5. PMID: 2655550

Curcumin works synergistically with paclitaxel to overcome multidrug resistance in tumor cells.
Mol Pharm. 2009 May-Jun;6(3):928-39. PMID: 19278222

Curcumin works synergistically with the chemotoxic agent FOLFOX to eliminate colon caner stem cells.
Transl Oncol. 2009 Dec;2(4):321-8. PMID: 19956394

Curcumin's (Turmeric) inhibition of HPV oncogenes is cytotoxic to cervical cancer cells.
Mol Carcinog. 2006 May;45(5):320-32. PMID: 16526022

Curcumin's ability to inhibit VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells indicate it may have value in irritable bowel syndrome and cancer.
Gut. 2008 Nov;57(11):1509-17. Epub 2008 Jul 2. PMID: 18596194

Curcumin's anti-inflammatory properties are related to its ability to inhibit the neutrophil response.
Agents Actions. 1989 Nov;28(3-4):298-303. PMID: 2556903

Curcumin's blood sugar lowering effect may be due to its inhibitory effect on hepatic gluconeogenesis.
Biochem Biophys Res Commun. 2009 Oct 16;388(2):377-82. Epub 2009 Aug 8. PMID: 19665995

Curcumin's higher binding affinity for iron and copper rather than zinc may contribute to its protective effect in Alzheimer's disease.
J Alzheimers Dis. 2004 Aug;6(4):367-77; discussion 443-9. PMID: 15345806

Curcumin's induction of programmed cell death in human leukemia cells is associated with inhibition of telomerase activity.
Mol Cell Biochem. 2007 Mar;297(1-2):31-9. Epub 2006 Nov 10. PMID: 17096185

Curcumin's proapoptotic and antidegranulation effect make it a potential candidate for the therapy of neutrophil-induced lung injury and sepsis.
Crit Care Med. 2005 Nov;33(11):2571-8. PMID: 16276182

Curcumin's various benefits may be associated with its role as a Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor.
J Enzyme Inhib Med Chem. 2009 Jun;24(3):771-8. PMID: 18720192

Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets.
Prostaglandins Leukot Essent Fatty Acids. 1995 Apr;52(4):223-7. PMID: 7784468

Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells.
J Mol Histol. 2004 Mar;35(3):301-7. PMID: 15339049

Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-Cell lymphoma cell line proliferation.
Acta Pharmacol Sin. 2005 May;26(5):603-9. PMID: 15842781

Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages.
Biochem Biophys Res Commun. 1995 Jan 17;206(2):533-40. PMID: 7530002

Curcumin, an antioxidant and anti-inflammatory agent protects endothelial cells against oxidative stress.
Biol Pharm Bull. 2006 Apr;29(4):670-4. PMID: 10889462

Curcumin, EGCG and resveratrol inhibit inflammation.
Mutat Res. 2001 Sep 1;480-481:243-68. PMID: 11506818

Curcumin, resveratrol and EGCG may have a therapeutic role in proliferative vitreoretinopathy (PVR).
Curr Eye Res. 2010 Nov;35(11):1021-33. PMID: 20958191

Curcumin, resveratrol and flavonoids act as anti-inflammatory, cyto- and DNA-protective dietary compounds.
Toxicology. 2009 Nov 10. Epub 2009 Nov 10. PMID: 19903510

Curcumin, Resveratrol and Gingerol decrease prostate inflammation
Carcinogenesis. 2007 Jun;28(6):1188-96. Epub 2006 Dec 6. PMID: 17151092

Curcumin, resveratrol and vanillin protects against DNA damage.
Minerva Med. 1988 May;79(5):387-90. PMID: 12561251

Curcumin-induced cell death of ovarian carcinoma has a known mechnism.
Mol Carcinog. 2010 Jan;49(1):13-24. PMID: 19676105

Curcumin-induced suppression of adipogenic differentiation, indicating its therapeutic role in obesity.
Am J Physiol Cell Physiol. 2010 Jun;298(6):C1510-6. Epub 2010 Mar 31. PMID: 20357182

Curcuminoids (from Turmeric) are effective in treating multi-drug resistance cancer cell lines.
Biochem Pharmacol. 2004 Nov 15;68(10):2043-52. PMID: 15476675

Curcuminoids are cytotoxic to human ovarian cancer cells.
J Nat Prod. 1998 Dec;61(12):1531-4. PMID: 9868158

Curcuminoids are potent inhibitors of lipid peroxidation.
J Pharm Pharmacol. 1994 Dec;46(12):1013-6. PMID: 7714712

Curcuminoids have anti-tumor and antioxidant activity.
Cancer Lett. 1995 Jul 20;94(1):79-83. PMID: 7621448

Curcuminoids inhibit multidrug resistance-associated protein.
Cancer Chemother Pharmacol. 2006 Feb;57(3):376-88. Epub 2005 Jul 14. PMID: 16021489

Curcuminoids inhibits breast cancer cell proliferation.
Pharmacol Res. 2010 Nov 25. Epub 2010 Nov 25. PMID: 9714342

Curcuminoids masy promote neuritogenesis.
J Agric Food Chem. 2012 Jan 11 ;60(1):433-43. Epub 2011 Dec 22. PMID: 22145830

Curcuminoids may enhance the efficacy of chemotoxic drugs.
Mol Cancer Ther. 2006 Aug;5(8):1995-2006. PMID: 16928820

Curcuminoids may provide an ideal solution to overcoming chemoresistance.
Mol Med Report. 2012 Sep 27. Epub 2012 Sep 27. PMID: 23023936

Curcuminoids may reduce the risk of hypertension and cardiovascular diseases.
Int J Food Sci Nutr. 2012 Jan 23. Epub 2012 Jan 23. PMID: 22263555

Curcuminoids prevent experimentally induced neuronal damage in the rat hippocampus.
Life Sci. 2006 Mar 13;78(16):1884-91. Epub 2005 Nov 2. PMID: 16266725

Curcuminoids protect against endothelial diseases caused by oxidative damages.
Exp Mol Med. 2006 Aug 31;38(4):393-400. PMID: 16953118

Curcuminoids protect against neuronal cell death in an Alzheimer disease model.
Neurosci Lett. 2001 Apr 27;303(1):57-61. PMID: 11297823

Curcuminoids rescue long-term potentiation impaired by amyloid peptide in rat hippocampal slices.
Synapse. 2010 Oct 20. Epub 2010 Oct 20. PMID: 20963814

Curcuminoids suppress the growth and induce programmed cell death in glioblastoma multiforme cells.
J Agric Food Chem. 2010 Oct 13;58(19):10639-45. PMID: 20822178

Curcuminoids suppress the growth of pharynx and nasopharyngeal cancer cells.
J Agric Food Chem. 2009 May 13;57(9):3765-70. PMID: 19317462

Curcuminoids, particularly curcumin, can improve the symptoms of allergic diseases, such as anaphylaxis and itching.
Arch Pharm Res. 2009 Dec;32(12):1783-7. Epub 2010 Feb 17. PMID: 20162408

Curcuminoids-loaded lipid nanoparticles exhibit anti-malarial activity.
Colloids Surf B Biointerfaces. 2010 Nov 1;81(1):263-73. Epub 2010 Jul 17. PMID: 20688493

Curcumoids inhibit matrix metalloproteinase-3 secretion in human invasive breast carcinoma cells.
Arch Pharm Res. 2010 Jul;33(7):989-98. Epub 2010 Jul 27. PMID: 20661707

Curcumol, isolated from Curcuma phaeocaulis (R. Curcumae) induces programmed cell death in human lung cancer cells.
Med Oncol. 2010 Feb 3. Epub 2010 Feb 3. PMID: 20127426

Demethoxycurcumin induces programmed cell death in human glioma cells.
Biochem Biophys Res Commun. 2009 Jul 10;384(4):420-5. Epub 2009 May 5. PMID: 19422808

Demethoxycurcumin suppresses migration and invasion of human breast cancer cell line.
Eur J Pharmacol. 2010 Feb 10;627(1-3):8-15. Epub 2009 Oct 7. PMID: 19818349

Demethoxycurcumin, a natural derivative of curcumin attenuates LPS-induced pro-inflammatory responses in microglia cells.
Int Immunopharmacol. 2010 Mar;10(3):331-8. Epub 2009 Dec 16. PMID: 20018257

Dietary omega-3 fatty acids, curcumin and capsaicin lower the release of lysosomal enzymes and eicosanoids in rat peritoneal macrophages associated with inflammation.
Mol Cell Biochem. 2000 Jan;203(1-2):153-61. PMID: 10724344

EGCG and curcumin have chemopreventive synergism in normal, premalignant and malignant human oral epithelial cells.
Carcinogenesis. 1998 Mar;19(3):419-24. PMID: 9525275

EGCG and curcumin suppress Alzheimer disease associated beta amyloid production.
Am J Physiol Heart Circ Physiol. 2005 Aug;289(2):H715-21. Epub 2005 Mar 18. PMID: 18695518

Ellagic acid and curcumin may inhibit cancer through preventing the over-expression of glutathione S-transferases.
Food Chem Toxicol. 2007 Feb;45(2):286-95. Epub 2006 Aug 30. PMID: 17046132

Epicatechin enhances the anti-cancer activity of curcumin in human lung cancer cells.
Cancer Prev Res (Phila). 2010 Aug;3(8):953-62. Epub 2010 Jul 6. PMID: 20606042

Epigenetic Reactivation of RANK in Glioblastoma Cells by Curcumin: Involvement of STAT3 Inhibition.
DNA Cell Biol. 2013 Apr 27. Epub 2013 Apr 27. PMID: 23621850

Ethanol extracts of A. hypogaea (peanut), C. longa (turmeric), and P. maritimum could be considered a new natural agent against the Acanthamoeba cyst.
Parasitol Res. 2011 Dec 7. Epub 2011 Dec 7. PMID: 22146994

Garcinol (Garcinia indica) and curcumin (Turmeric) induce programmed cell death in human leukemia cells.
J Agric Food Chem. 2001 Mar;49(3):1464-74. PMID: 11312881

Genistein and curcumin block migratory and invasive phenotypes within mouse skin cells.
Nutr Cancer. 2000;37(1):49-54. PMID: 10965519

Heat-solubilized curry spice curcumin inhibits antibody-antigen interaction in in vitro studies indicating it may help to alleviate autoimmune diseases.
Mol Nutr Food Res. 2010 Aug;54(8):1202-9. PMID: 20146265

Hexahydrocurcumin has a cytotoxic effect against human colorectal cancer cells.
Nat Prod Commun. 2011 Nov ;6(11):1671-2. PMID: 22224285

High dose of curcumin might be an effective anti-angiogenic drug in the treatment against tumor.
Mol Pharmacol.2007 Dec;72(6):1508-21. Epub 2007 Sep 14. PMID: 16151260

Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin.
Eur J Pharmacol. 1999 Nov 19;384(2-3):191-5. PMID: 10611441

Liposome-encapsulated curcumin exhibits anti-cancer activity in pancreatic cancer.
Cancer. 2005 Sep 15;104(6):1322-31. PMID: 16092118

Liposome-encapsulated curcumin suppresses neuroblastoma growth.
Surgery. 2012 Jan 26. Epub 2012 Jan 26. PMID: 22284765

MGN-3 and curcumin exhibit synergistic anti-cancer activity on human multiple myeloma cell lines.
Neoplasma. 2011;58(2):118-23. PMID: 21275460

NAC and curcumin ameliorate pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells.
Environ Monit Assess. 2010 Nov 4. Epub 2010 Nov 4. PMID: 21049288

Natural curcuminoids exhibit alpha-glucosidase inhibitory activity.
Eur J Med Chem. 2006 Feb;41(2):213-8. Epub 2006 Jan 4. PMID: 16387392

Natural plant compounds may have preventive and therapeutic applications against the growth of breast tumors induced by environmental estroge
Environ Health Perspect. 1998 Dec;106(12):807-12. PMID: 9831541

Phenethyl isothiocyanate and sulforaphane or curcumin and sulforaphane have a synergistic effect in the inhibition of inflammation.
Pharm Res. 2009 Jan;26(1):224-31. Epub 2008 Oct 8. PMID: 18841446

Phosphatidylcholine bound curcumin is a lipoxygenase inhibitor.
Lipids. 1998 Dec;33(12):1223-8. PMID: 9930409

Polyphenols such as curcumin and EGCG from green tea may chelate out iron from the Alzheimers brain.
Prog Neurobiol. 2007 Aug;82(6):348-60. Epub 2007 Jun 19. PMID: 17659826

Preventive compounds curcumin and piperine are capable of targeting breast stem cells.
Breast Cancer Res Treat. 2010 Aug ;122(3):777-85. Epub 2009 Nov 7. PMID: 19898931


Prophylactic use of curcumin may effectively rescue pancreatic islets from damage without affecting the normal function of these cellular structures.
BJU Int. 2002 Jun;89(9):829-34. PMID: 17900558

Resveratrol and curcumin may attenuate Chlamydia-associated induced atherosclerosis.
Biochem Biophys Res Commun. 2005 Jul 22;333(1):21-7. PMID: 15939398

Review: Anti cancer effects of curcumin.
Cell Div. 2008;3:14. Epub 2008 Oct 3. PMID: 18834508

Review: antiangogenic effect of selected phytochemicals.
Pharmazie. 2010 Jan;65(1):57-63. PMID: 20187580

Review: Curcumin content of turmeric and curry powders.
Nutr Cancer. 2006;55(2):126-31. PMID: 17044766

Review: Curcumin has a number of potential therapeutic properties for Alzheimer diseaes.
Mutat Res. 2009 Oct 13. Epub 2009 Oct 13. PMID: 19966973

Review: Curcumin has potential value in the treatment of inflammatory bowel disease.
J Lab Clin Med. 1997 Dec;130(6):576-84. PMID: 19519446

Review: Curcumin has therapeutic potential in the treatment of head & neck cancers.
Mol Cancer. 2011 Feb 7;10(1):12. Epub 2011 Feb 7. PMID: 21299897

Review: Curcumin may be an ideal anti-cancer therapy due to is role in positively modulating the machineries of cell survival, proliferation, invasion, and angiogenesis.
Mol Cell Biochem. 2010 Mar;336(1-2):85-95. Epub 2009 Oct 14. PMID: 19826768

Review: curcumin may be an ideal epigenetic agent.
Cancer. 2010 Oct 15;116(20):4670-6. PMID: 20597137

Review: Curcumin may have therapeutic value in obesity.
Pediatr Rehabil. 2004 Oct-Dec;7(4):245-60. PMID: 21091916

Review: Curcumin selectively kills tumor cells.
Scand J Prim Health Care. 1998 Mar;16(1):37-9. PMID: 19590964

Review: Potentials of curcumin as an antidepressant.
ScientificWorldJournal. 2009;9:1233-41. Epub 2009 Nov 1. PMID: 19882093

Safety Study: A two generation reproductive toxicity study with curcumin, turmeric yellow, in Wistar rats.
Food Chem Toxicol. 2007 Jan;45(1):64-9. Epub 2006 Aug 7. PMID: 16987575

Six dietary constituents inhibit nicotine-DNA adduct formation.
Food Chem Toxicol. 2003 Jul;41(7):1045-50. PMID: 12804663

Spice constituents such as quercetin and curcumin inhibit LDL cholesterol oxidation.
Mol Cell Biochem. 2002 Jan;229(1-2):19-23. PMID: 11936843

Targeting Cancer Stem Cells by Curcumin and Clinical Applications.
Cancer Lett. 2014 Jan 23. Epub 2014 Jan 23. PMID: 24463298

Tea, rosemary and turmeric inhibit inflammation.
Cancer Lett. 1995 Sep 4;96(1):23-9. PMID: 7553604

Testoterone enhances curcumin's anti-prostate cancer activity.
Cancer Sci. 2011 Feb;102(2):468-71. Epub 2010 Dec 7. PMID: 21134073

Tetrahydrocurcumin inhibits cell migration and invasion in fibrosarcoma cells.
Acta Pharmacol Sin. 2008 Jul;29(7):853-60. PMID: 18565284

Tetrahydrocurcumin may contribute to overcoming multi-drug resistance of human cancers.
Mol Cell Biochem. 2007 Feb;296(1-2):85-95. Epub 2006 Sep 8. PMID: 16960658

Tetrahydrocurcumin protect against radiation-induced lipid peroxidation.
Appl Physiol Nutr Metab. 2009 Dec;34(6):1093-7. PMID: 10803946


Tetrahydrocurcumin protect against radiation-induced lipid peroxidation.
Appl Physiol Nutr Metab. 2009 Dec;34(6):1093-7. PMID: 10803946

The anti-breast cancer activity of curcumin may be due in part to its down-regulation of insulin-like growth factor.
Life Sci. 2007 May 16;80(23):2161-9. Epub 2007 Apr 21. PMID: 17499312

The dietary polyphenols trans-resveratrol and curcumin interact with cannabinoid receptors indicating their potential role in treating obesity and/or drug dependence.
Biosci Biotechnol Biochem. 1996 Jun;60(6):1000-5. PMID: 19359525

The natural compounds berberine, curcumin and picroliv are able to suppress the progression of virally induced leukemia.
J Exp Ther Oncol. 2008;7(4):275-84. PMID: 19227007

The natural Nuclear factor-kappaB inhibitor curcumin may help to overcome drug resistance in human pancreatic cancer.
Mol Cancer Ther. 2006 Sep;5(9):2251-60. PMID: 16985059

The phytoestrogens quercetin, baicalein, genistein, epigallocatechin gallate (EGCG), and curcumin are effective inhibitors of prostate tumor cell growth.
Nutr Cancer. 2004;49(2):200-8. PMID: 15489213

The plant extracts curcumin, quercetin, green tea, balcalein, and luteolin offer protection and promote healing of neurological tissues
Surg Neurol Int. 2012 ;3:19. Epub 2012 Feb 15. PMID: 22439110

The plant polyphenols curcumin, carnosic acid, and silibinin may work synergistically to inhibit acute myeloid leukemia cells.
Nutr Cancer. 2010 Aug;62(6):811-24. PMID: 20661831

The polyphenols, epigallocatechin gallate, and catechin hydrate significantly attenuate quinolinic acid-induced excitotoxicity in human neurons.
FEBS J. 2010 Jan;277(2):368-82. Epub 2009 Dec 10. PMID: 20015232

The role of cancer stem cells in the anti-carcinogenicity of curcumin.
Mol Nutr Food Res. 2013 Jul 31. Epub 2013 Jul 31. PMID: 23900994

Theophylline and curcumin may restore corticosteroid insensitivity.
Expert Opin Ther Targets. 2007 Jun;11(6):745-55. PMID: 17504013

There is strong evidence to support the use of curcumin in retinal diseases, Crohn's disease and disorders related to the spinal cord.
Arch Otolaryngol Head Neck Surg. 2004 Dec;130(12):1381-6. PMID: 15262811

Topic turmeric may have photoprotective properties.
J Cosmet Dermatol. 2011 Dec ;10(4):260-5. PMID: 22151933

Topical application of curcumin (from Turmeric) may have therapeutic value in the treatment of scleroderma, psoriasis and skin cancer.
Adv Exp Med Biol. 2007;595:343-57. PMID: 17569219

Topical application of curcumin was useful in reducing experimental corneal neovascularization and can be used to inhibit angiogenesis in the cornea.
Curr Eye Res. 2010 Apr;35(4):274-80. PMID: 20373893

Topical curcumin can inhibit deleterious effects of upper respiratory tract bacteria on human oropharyngeal cells.
Support Care Cancer. 2010 May 14. Epub 2010 May 14. PMID: 20467756

Topical curcumin with visible light may have therapeutic value in skin cancer.
J Invest Dermatol. 2007 Aug;127(8):1992-2000. Epub 2007 Apr 5. PMID: 17410200

Trichostatin A works synergistically with curcumin to inhibit human leukemia cells.
Pharmazie. 2006 Aug;61(8):710-6. PMID: 16964716

Tumeric contains compounds such as tumerones and curlone separate and distinct from curcumin which exhibit antibacterial activity.
J Agric Food Chem. 1999 Oct;47(10):4297-300. PMID: 10552805

Turmeric and curcumin inhibit aflatoxin induced hemolysis.
Evid Based Complement Alternat Med. 2010 Jan 4. Epub 2010 Jan 4. PMID: 17665866

Turmeric and curcumin protect against gamma-radiation-induced chromosome aberrations in Chinese hamster ovary cells.
Teratog Carcinog Mutagen. 1999;19(1):9-18. PMID: 10321406

Turmeric and ginger work synergistically to suppress prostate cancer cell lines.
J Basic Clin Physiol Pharmacol. 2012 Oct 12 ;0(0):1-8. Epub 2012 Oct 12. PMID: 23072849

Turmeric and green tea have significant apoptic effects in chronic lymphocytic leukemia.
Clin Cancer Res. 2009 Feb 15;15(4):1123-5. PMID: 19228716

Tetrahydrocurcumin protect against radiation-induced lipid peroxidation.
Appl Physiol Nutr Metab. 2009 Dec;34(6):1093-7. PMID: 10803946

The anti-breast cancer activity of curcumin may be due in part to its down-regulation of insulin-like growth factor.
Life Sci. 2007 May 16;80(23):2161-9. Epub 2007 Apr 21. PMID: 17499312

The dietary polyphenols trans-resveratrol and curcumin interact with cannabinoid receptors indicating their potential role in treating obesity and/or drug dependence.
Biosci Biotechnol Biochem. 1996 Jun;60(6):1000-5. PMID: 19359525

The natural compounds berberine, curcumin and picroliv are able to suppress the progression of virally induced leukemia.
J Exp Ther Oncol. 2008;7(4):275-84. PMID: 19227007

The natural Nuclear factor-kappaB inhibitor curcumin may help to overcome drug resistance in human pancreatic cancer.
Mol Cancer Ther. 2006 Sep;5(9):2251-60. PMID: 16985059

The phytoestrogens quercetin, baicalein, genistein, epigallocatechin gallate (EGCG), and curcumin are effective inhibitors of prostate tumor cell growth.
Nutr Cancer. 2004;49(2):200-8. PMID: 15489213

The plant extracts curcumin, quercetin, green tea, balcalein, and luteolin offer protection and promote healing of neurological tissues
Surg Neurol Int. 2012 ;3:19. Epub 2012 Feb 15. PMID: 22439110

The plant polyphenols curcumin, carnosic acid, and silibinin may work synergistically to inhibit acute myeloid leukemia cells.
Nutr Cancer. 2010 Aug;62(6):811-24. PMID: 20661831

The polyphenols, epigallocatechin gallate, and catechin hydrate significantly attenuate quinolinic acid-induced excitotoxicity in human neurons.
FEBS J. 2010 Jan;277(2):368-82. Epub 2009 Dec 10. PMID: 20015232

The role of cancer stem cells in the anti-carcinogenicity of curcumin.
Mol Nutr Food Res. 2013 Jul 31. Epub 2013 Jul 31. PMID: 23900994

Theophylline and curcumin may restore corticosteroid insensitivity.
Expert Opin Ther Targets. 2007 Jun;11(6):745-55. PMID: 17504013

There is strong evidence to support the use of curcumin in retinal diseases, Crohn's disease and disorders related to the spinal cord.
Arch Otolaryngol Head Neck Surg. 2004 Dec;130(12):1381-6. PMID: 15262811

Topic turmeric may have photoprotective properties.
J Cosmet Dermatol. 2011 Dec ;10(4):260-5. PMID: 22151933

Topical application of curcumin (from Turmeric) may have therapeutic value in the treatment of scleroderma, psoriasis and skin cancer.
Adv Exp Med Biol. 2007;595:343-57. PMID: 17569219

Topical application of curcumin was useful in reducing experimental corneal neovascularization and can be used to inhibit angiogenesis in the cornea.
Curr Eye Res. 2010 Apr;35(4):274-80. PMID: 20373893

Topical curcumin can inhibit deleterious effects of upper respiratory tract bacteria on human oropharyngeal cells.
Support Care Cancer. 2010 May 14. Epub 2010 May 14. PMID: 20467756

Topical curcumin with visible light may have therapeutic value in skin cancer.
J Invest Dermatol. 2007 Aug;127(8):1992-2000. Epub 2007 Apr 5. PMID: 17410200

Trichostatin A works synergistically with curcumin to inhibit human leukemia cells.
Pharmazie. 2006 Aug;61(8):710-6. PMID: 16964716

Tumeric contains compounds such as tumerones and curlone separate and distinct from curcumin which exhibit antibacterial activity.
J Agric Food Chem. 1999 Oct;47(10):4297-300. PMID: 10552805

Turmeric and curcumin inhibit aflatoxin induced hemolysis.
Evid Based Complement Alternat Med. 2010 Jan 4. Epub 2010 Jan 4. PMID: 17665866

Turmeric and curcumin protect against gamma-radiation-induced chromosome aberrations in Chinese hamster ovary cells.
Teratog Carcinog Mutagen. 1999;19(1):9-18. PMID: 10321406

Turmeric and ginger work synergistically to suppress prostate cancer cell lines.
J Basic Clin Physiol Pharmacol. 2012 Oct 12 ;0(0):1-8. Epub 2012 Oct 12. PMID: 23072849

Turmeric and green tea have significant apoptic effects in chronic lymphocytic leukemia.
Clin Cancer Res. 2009 Feb 15;15(4):1123-5. PMID: 19228716



PATENTS

Process for extracting curcumin   
CN103254050
The invention provides a process for extracting curcumin by a carbon dioxide supercritical extraction method. According to the process, curcumin is extracted from ginger by taking a supercritical carbon dioxide liquid as an extractant and 95% ethanol as an entrainer. The method adopted is simple in flow and convenient to operate. Separation is realized at the same time in the extraction process, and the method has no bad effect on production personnel and the environment. The yield and purity of curcumin are high.

Preparation method for extracting purified curcumin-related compounds from turmeric
CN103193610
The invention discloses a preparation method for extracting purified curcumin-related compounds from turmeric. The process comprises the following steps of: performing water washing and crushing on the turmeric, performing multi-stage countercurrent extraction by using alcohol-amino acid water, performing chromatography through a macroporous resin column, performing gradient elution by using ethanol-water, collecting eluate, performing decompression, evaporation and concentration, and performing vacuum drying to obtain active ingredients, namely curcumin, demethoxycurcumin and bisdemethoxycurcumin. The preparation method disclosed by the invention has the advantages that the alcohol-amino acid water is used for performing the multi-stage countercurrent extraction, the used macroporous resin can be utilized repeatedly, water and ethanol are taken as solvents, the preparation method is economic, simple and convenient, high-purity curcumin, demethoxycurcumin and bisdemethoxycurcumin can be conveniently obtained, the purity of each monomer compound is above 95%, the sample recovery rate is above 75%, the process flow is short, the operability is strong, the consumption of the solvents is low, the extraction rate is high, the stability of the extraction solution is good, obtained products can be widely used for the fields of medicines, foods and the like, and the preparation method is suitable for mass production.

High-yield water-based curcumin extraction method
CN103130629
The invention relates to a high-yield water-based curcumin extraction method which comprises the following steps: (1) grinding curcuma, soaking with an alkaline water solution of 0-40 DEG C, stirring, extracting, then adding antioxidant, centrifuging, extracting 1-2 times, taking the supernatant, and adding acid to precipitate; and (2) adding an alcohol solution to dissolve the precipitate, centrifuging, adding water to obtain an alcohol dissolving liquid, purifying, concentrating, and drying to obtain curcumin. The curcumin content extracted by the invention can be up to 95%; the extraction and purification yield is more than 80%; and by taking water as extraction solvent, the method is economic, convenient and safe. Thus, the method provided by the invention is a high-yield and low-cost production process.

Method for extracting curcumin from turmeric
CN102617316
The invention relates to a method for extracting curcumin from turmeric. The method is characterized by comprising the following steps that: the turmeric is cleanly cleaned and is then crushed into turmeric powder, the turmeric powder and extraction solvents are mixed according to a certain proportion and are then subjected to backflow extraction, next, the separation is carried out under certain conditions to remove heavy metals, and finally, the precipitates are separated and crystallized to obtain curcumin.; Compared with the prior art, the method has the advantages that the heavy metal separation and purification flow process is simple and short, the risk of secondary pollution caused by the additional addition of absorption agents or absorption media is avoided, and the heavy metal residue of products can be purified to a degree that the lead content is lower than 1.0PPM, the cadmium content is lower than 1.0 PPM, the mercury content is lower than 0.10 PPM, and the arsenic content is lower than 0.10PPM.

Method for extracting and separating high-purity curcumin with low heavy-metal residues from turmeric
CN102603505
The invention discloses a method for extracting and separating high-purity curcumin with low heavy-metal residues from turmeric. The method comprises the following steps of: firstly cleaning, drying and crushing turmeric into turmeric powder, and mixing the turmeric powder with an extraction solvent proportionally, heating, stirring and extracting; mixing extractive solutions, filtrating and separating, removing the filter residue to obtain filtrate, and concentrating the filtrate; cooling the remaining concentrated liquid, mixing the liquid with a crystallization solvent proportionally, and carrying out static crystallization in a suitable temperature range and filtrating the mixture to obtain wet crystal product; and finally mixing the crystallization solvent with water proportionally to prepare a mixed solvent, mixing the wet crystal product with the mixed solvent proportionally and recrystallizing, and separating to obtain high-purity curcumin with low heavy-metal residues. The technology provided by the invention can reduce the heavy metal content as much as possible while retaining effective natural ingredients of traditional Chinese medicine at the same time, and the technology has significant meaning in improving the standard system of safety control for traditional Chinese medicine, breaking the foreign technical barriers and really pushing traditional Chinese medicine to go onto the world market.

Method for extracting and separating curcumin and curcuma oil from carcuma longa
CN102408320
The invention discloses a method for extracting and separating curcumin and curcuma oil from carcuma longa, which comprises the following steps of: grinding the carcuma longa into carcuma longa powder with particle size of 80-100 meshes; taking ethanol water solution as extractant for dynamic countercurrent extraction of the carcuma longa powder to obtain extraction solution, and concentrating to obtain concentrated solution; and adding the concentrated solution with plant oil extraction solvent for liquid-liquid extraction to obtain light phase containing curcuma oil and heavy phase containing curcumin. Compared with the prior art, the invention takes the ethanol water solution as the extractant and extracts the curcumin and the curcuma oil from the carcuma longa by employing the dynamic countercurrent extraction method, and the method has the advantages of simple operation, moderate extraction condition, low usage amount of solvent, short extraction time, few impurities in extraction solution and high extraction efficiency.

Process method for microwave assistant supercritical extraction of active ingredients of curcuma
CN102100875
The invention discloses a process method for microwave assistant supercritical extraction of active ingredients of curcuma. In the method, the active ingredients, namely curcumin and fat soluble curcuma oil, of curcuma are extracted by the synergistic action of the microwave technology and the supercritical technology. The process method mainly comprises the following steps of: performing microwave intermittent sudden heating and then carbon dioxide (CO2) supercritical extraction; separating CO2 and curcuma oil in an analyzing kettle; and adding water or ethanol into curcuma residue in a solid-to-liquid weight ratio of 1:7-14, and performing microwave action, twice soaking, filtration, condensation and spray drying to obtain the curcumin.; The process method solves the problem that in the prior art, only single active ingredient can be extracted or the compositions of the extract are not balanced, and realizes the extraction of two main active ingredients, namely curcuma oil and curcumin, of the curcuma at the same time, and the yield is over 8 percent and 13 percent respectively. The process method is the physical method and has the advantages of no product pollution, high purity, low cost, simple process and easy mass production.

Extracting method for curcumin
CN101831199
The invention discloses an extracting method for curcumin, comprising the following steps: pulverizing curcuma; pelleting the pulverized curcuma under the condition of introducing steam; and extracting particles obtained by pelleting with leach liquor. Since turmeric roots contain a large amount of starch which can be gelatinized in a manner of introducing steam for heating and has stickiness, thus the turmeric powder can be more compactly combined, has large rigidity, and is not easy to break; the prepared particles are provided with many micropores, and the solvent is easy to permeate, thus the extraction rate is high; and in addition, the gaps among the particles are larger than the gaps among the powdery materials, thus the solvent is more easy to permeate and the rate of filtration is high, thereby improving the extraction rate, the rate of filtration and the production efficiency.

Curcumin purification technique
CN101774899
The invention relates to a curcumin purification technique. The technique adopts fresh curcuma longa as material, the curcuma longa is ground, squeezed and filtered, ethyl ether is added for extraction, so that volatile oil is removed, and after separation and purification conducted by way of cation exchange resin, membrane concentration and alumina column chromatography and recrystallization conducted by way of methanol, the product is obtained. The method has the advantages of high product purity, simple operation, high throughput and easy industrialized production.

Purification technology of curcumin compound
CN101768061
The invention discloses a purification technology of a curcumin compound. Turmeric medicine serves as a raw material to be smashed and extracted by petroleum ether in a backflow mode; residue is subjected to ultrasound assistant extraction after warm immersing by sodium salicylate alcoholic solution; macroporous resin is added into extract to be separated and purified; mixture is eluted by acetone-2% glacial acetic acid (50:50); curcumin, demethoxy curcumin and bisdemethoxy curcumin fraction are respectively collected; reagent is recovered and is respectively dissolved by a small quantity of acetone; water of which the amount is three times of acetone is quickly added to be decentralized; and supernate is removed, and the mixture is precipitated, frozen and dried to obtain the product.
Curcumin A as well as preparation method thereof and applications to preparing medicaments for treating cardiovascular and cerebrovascular diseases

Method for preparing curcumin, demethoxycurcumin and bisdemethoxycurcumin
CN101585757
The present invention discloses a method for preparing curcumin, demethoxycurcumin and bisdemethoxycurcumin, which comprises the following steps: continuously executing countercurrent extraction to the turmeric with the methanol-acid solution or ethanol-acid solution, after filtering the extracted solution, condensing into the oleoresin with the relative density of 0.9-1.2; placing the oleoresin on the chromatographic separation medium for gradient elution, and after fraction-collecting the eluent, respectively obtaining the curcumin crystal, demethoxycurcumin crystal and bisdemethoxycurcumin crystal after condensing. The invention adopts a technique in which HZ-816, HZ-818 or HZ-801 is used as the chromatographic separation medium and the alcohol-water is used as the elution solvent.; Three monomeric compounds of curcumin, demethoxycurcumin and bisdemethoxycurcumin are simultaneously obtained. The purity of each monomeric compound is more than 95%, and the recovery rate of the sample is more than 70%. The method of the invention further has the advantages of less intercrossing of compounds in the separation process, short flow path, strong operability, low consumption of the solvent, high extraction rate and excellent stability of the extraction solution. Furthermore the obtained product can be widely applied for the fields of medicament, food, etc., and is suitable for large-scale production.

Method for extracting refined curcumin and curcuma oil from curcuma
CN101445440
The invention relates to a method for extracting refined curcumin and curcuma oil from curcuma. The method comprises the following steps: the curcuma is cleaned, dried in the shade, crushed into 30-40 mesh curcuma powder, low-carbon alcohol and alkyl hydrocarbon are made into a mixed solvent at the volume ratio of 1:1-3, the curcuma powder and the mixed solvent are mixed at a weight ratio of 1:3-5 for extraction twice; the extracts are merged, filtered, separated and removed from dregs, the obtained filtrate is condensed, the concentration level is controlled at 60-90%, and the solvent is recovered; a separating agent containing 0-3% salt is added to the residual concentrated solution, the addition amount of the separating agent is 0.5-2 times of the volume of the concentrated solution, the obtained mixture is kept standing for demixing after evenly stirred; a supernatant is separated and condensed, and the alkyl hydrocarbon is recovered to obtain the curcuma oil; a subnatant is adsorbed by a macroporous absorbent resin, flushed to remove water soluble impurities, and eluted with a desorbent, the solvent is condensed and recovered to crystallize the curcumin, thus obtaining the curcumin with the content more than 95%.

Method for extracting and separating curcuma oil
CN101407743
The invention relates to a method for extracting and separating turmeric oil, which comprises the step of extracting the turmeric oil from curcumas by using supercritical CO2, and is characterized in that the method also comprises the following steps: adopting first-step molecular distillation to separate curcumin and grease in the turmeric oil obtained by using the supercritical CO2 method; obtaining almost colorless turmeric essential oil under the conditions of operating pressure of 10 to 20Pa, distillation temperature of 70 to 90 DEG C, the rotation speed of a blade applicator of 200 to 300r/min and distillates of more than 75.0 percent. Adopting supercritical CO2 extraction and two-level molecular distillation, the method can effectively keep the natural ingredients of the turmeric oil, without bringing any pollution to the environment.; In addition, the method also realizes the separation of oxygenous sesquiterpene from sesquiterpene in the turmeric oil, which can be used directly as raw materials in the fields such as the cosmetics, food and pharmacy where different amounts of the oxygenous sesquiterpene and the sesquiterpene are needed.

Method for extracting and separating turmeric effective ingredient curcumin
CN101468944
The invention discloses a method for extracting and separating curcumin as an effective constituent of turmeric, which belongs to the extraction and separation of traditional Chinese medicine effective constituents and technical application. The structural formula of the compound is as shown in a figure. The method for extracting and separating curcumin comprises the steps of grinding turmeric, adding alkali liquid for cold extraction, filtering, performing column chromatography through macroporous resin, performing gradient elution by use of ethanol and water, collecting eluent, reducing pressure, evaporating, concentrating and vacuum-drying the eluent, and obtaining the effective constituent, namely curcumin. The method has the advantages that the macroporous resin used in the method can be repeatedly utilized, and the method is economical and simple by taking water and ethanol as solvents, can conveniently obtain the extract with the effective constituent content not lower than 90 percent, and is easy to industrialize.





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