Jean Solomides
Physiatrons vs Cancer
Dr
Jean Solomides
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Jean Solomidès 1 de 2
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https://fr.wikipedia.org/wiki/Jean_Solomid%C3%A8s
Jean Solomides
Jean Solomides , born Yangos Solomides, the 28 February 1911 ,
In Cyprus, is a French doctor , researcher and biologist of
Cypriot origin, who worked at the Institut Pasteur from 1938 to
1947. He died in France, 28 May 1979 .
Biography
Jean Solomides comes to France to study, physics, chemistry,
natural sciences. He graduated from the Sorbonne with a Bachelor
of Science degree, and in 1938 obtained a degree in medicine.
Research fellow at the CNRS , he is seconded to the Institut
Pasteur and works on tuberculosis . Detached in Toulouse during
the war, he passed a degree in natural sciences. With his
teacher Frédéric Van Deinse 1 , he studied tubercle bacilli and
the effects of oils, fats, glycerin on bacilli in the organism
of laboratory animals. At the time of the Liberation, he was a
trainee at the CNRS and then a researcher in 1945. He discovered
in 1947 that synthetic peroxidases (oxidation catalysts)
destroy, by oxidation, cultures of tuberculous bacilli, but also
cancer cells by Selectively fixing on their membrane. On March
4, 1948, he made a communication on his method to the French
Society of Microbiology, published in the Annals of the Institut
Pasteur and in more than sixty other scientific publications.
In 1949, he obtained French citizenship for acts of resistance .
In the same year, he cured his father with an inoperable liver
tumor for which the Cypriot doctors call him condemned.
Solomides sends to Cyprus ampoules of iodized distillate of cod
liver oil in solution to treat his father. Three weeks later,
the doctors noticed to their surprise that the tumor had
disappeared [citation needed] . His father is completely cured 2
.
The cure of his father arouses negative reactions at the
Institut Pasteur [ref. Required] . Indeed, this healing, its
experiments on glycerin that have proved that the artificial
immunity is transient and "that question the usefulness of
vaccinations which make up the majority of the resources of the
Pasteur Institute", are worried. He was dismissed from the
Institute at the end of 1949 , against the will of Professor Van
Deinse 3 . He then installed his laboratory in the cellar of his
pavilion at Sceaux with the help of a doctor. In 1951 and 1952,
he obtained the MA for Citral-Urethane and Geranyl 4 , against
bronchitis, eczema, allergies, and as analgesics in the
treatment of cancer. In Belgium, the drug is tested and
reimbursed by the Social Security.
In 1955, Georges de Caunes invited him to French
radio-television with two or three patients. As a result of this
emission, many patients contact him in order to try this
treatment much less heavy than the ordinary treatment. In
October 1956, Solomides created a popularization magazine,
Victories on Cancer , and the World League for Cancer
Chemotherapy , the League later became the sick Human Rights
League , and the magazine became Remedies-News .
His life then becomes a series of struggles to officially
recognize his discoveries. His cancer drugs do not receive AMM
although they legally cure the sick with doctors collaborators,
and he has to face many lawsuits for "illegal practice of
medicine" 5 .
Despite the relentlessness of the Seine Medical Doctors' Chamber
of the Ministry of Health, thousands of patients have been cured
or improved, thanks to their findings 6 , 7 , 8 9 .
He died exhausted , in May 1979, at 68 years, from a pulmonary
embolism .
He was publicly defended by the artist Philippe Druillet in
Charlie Hebdo (June-July 1979) 10 .
Publications
1952: Chemotherapy of cancer considered as a virus disease: 1.
Aldehydes (in collaboration with Dr. E. Ronsin)
1969: Physiatry and synthetic physiatrists (Institut Solomides).
Bibliography
Laurent Dailliez , Fight against cancer: the works and cures of
Dr. Jean Solomides , Le Hameau, Paris, 1974, 252 p.
André Conord, The Solomidès Case , Jean-Jacques Pauvert , 1980 (
ISBN 978-2720200816 )
Friday , magazine proposed by André Campana : Parallel medicine
or charlatans? , Survey and realization of Jean-Marie Perthuis (
FR3 , Friday 28 March 1984:
http://www.ina.fr/archivespourtous/index.php?vue=notice&id_notice=DVC8408089001
)
Pierre Lance , Cursed scholars, Researchers excluded , Volume 1
(Presses de Valmy, 2001, Guy Trédaniel , 2003), ( ISBN
978-2844454577 )
Simone Brousse, Cancer , Cancer , Ed. Garancière, ( ISBN
978-2734000334 ) , p. 334
Synthetic physiatrists and cancer , published under the
supervision of Dr. Roger Bocquet , Maloine, 1981 ( ISBN
978-2224007959 ) .
Notes and
references
"French physician and biologist of Dutch origin, born in Batavia
(Dutch East Indies) on 21/06/1890, died on 06/03/1974 Royal
Dutch Navy Medical Officer Chief of the laboratory of
bacteriology and clinical serology of The University of Leiden
(Holland) (1926-1928), assistant chief of laboratory and head of
the BCG department at the Institut Pasteur, Paris (1931-1960),
head of the BCG department at the Institut Pasteur " [1]
Revue Remèdes and André Conord, L'Affaire Solomides , Pauvert,
1980, p. 91.
André Conord, The Affair Solomides , Jean-Jacques Pauvert ,
1980, p. 92.
two oils of vegetable origin with ether-oxide of
olyethylene-glycol. The Geranyl was experimented in Villejuif, a
small laboratory, Biostabilex, operates the visas until 1972
See the detail on:
http://lucadeparis.free.fr/infosweb/solomides.htm
Revue Remèdes , n ° 1 to 72
Simone Brousse, Cancer , Cancer , Ed. Garancière, p.334.
Synthetic physiatrists and cancer , published under the
direction of Dr. Roger Bocquet , Maloine.
http://www.ina.fr/sciences-et-techniques/medicine-sante/video/DVC8408089001/medecines-paralleles-ou-charlatans.fr.html
André Conord, The Affair Solomides , Jean-Jacques Pauvert ,
1980, p. 293, 336, 376.
http://lucadeparis.free.fr/infosweb/solomides.htm
Jean Solomides
Sources:
[A] André Conord, 1977, 1980: The Solomidès Case (Pauvert, 1980)
[index] .
[B] Dr Philippe Lagarde : "Classical and complementary medicines
are inseparable", in Alternative Health - The Impatient , Nº
239, November 1997, p. 40-41.
[C] Christian Bécant: The case Solomides (
http://perso.wanadoo.fr/afb/revue-affaire-solomides.htm ).
[D] Apostrophes , television broadcast on Antenne 2, October 14,
1977 (
http://www.ina.fr/art-et-culture/litterature/video/CPB77057447/de-l-angoisse.fr.html
) and November 4 1977 (
http://www.ina.fr/art-et-culture/litterature/video/CPB77058107/alors-ces-francais-en-40.fr.html
) [03/06/2009].
Friday , magazine proposed by André Campana: Parallel medicine
or charlatans? , Investigation and realization of Jean-Marie
Perthuis (FR3, Friday 28 March 1984:
http://www.ina.fr/sciences-et-techniques/medecine-sante/video/DVC8408089001/medecines-paralleles-ou-charlatans.fr
.html ) [03/06/2009].
Laurent Dailliez,, 1974: Fight against cancer: the works and
cures of Dr. Jean Solomides (Le Hameau, Paris).
"The potion of Doctor Solomides", Sept to Eight of Sunday 15
June 2008, on TF1, 18:50 ,
Yangos Solomides was born in Cyprus on February 28, 1911, with
British nationality. [A: 85]
He chose to study medicine in France, in order to do research
afterwards. [A: 86]
In 1929, he made his PCN (undergraduate degree in physics,
chemistry, natural sciences) in Montpellier, and in 1930 his
first year of medicine. [A: 86]
He prepares a science degree at the Sorbonne, which will allow
him to access teaching or research. [A: 86]
In 1937 and 1938, he acquired the certificates of biological
chemistry, mineralogy and general physiology, these three
certificates constituting a license [A: 86-87].
On November 24, 1938, he passed his Doctor of Medicine thesis at
the University of Paris [A: 87].
In 1939, he obtained the diploma of bacteriology of the Faculty
of medicine of Paris [A: 87].
He worked at the Institut Pasteur, in 1938 on tuberculosis, and
in 1939 and 1940 on the bacillus of Koch [A: 87]. He is a
researcher at the CNRS, seconded for eight years to the Institut
Pasteur [A: 80-81].
During the war, he was assigned to residence in Toulouse, and
obtained in 1943 and 1944 certificates of general chemistry,
physical chemistry and general botany at the University of
Toulouse, and was thus licensed in natural sciences. [A: 87]
From 1940 to 1944, in collaboration with his master Frédéric Van
Deinse, head of the BCG department at the Institut Pasteur, he
is studying tubercle bacilli, their effects on rabbits and
guinea pigs, oils and Fatty substances on the bacilli and on the
organism of experimental animals, for example on the sensitizing
or on the contrary immunizing properties of glycerine. [A: 87]
On the liberation of France, he became a trainee at CNRS and
then researcher in 1945. [A: 88]
He sells to the Walter laboratories an ointment, Gadistol, based
on distillate of cod liver oil, against eczema, skin cancers and
especially radiodermitis (precancerous skin lesions, caused by
X-rays or gamma). [A: 88]
In 1947 or 1948 he discovered that synthetic peroxidase
(oxidation catalysts) destroyed cultures of tubercle bacilli by
oxidizing them, but also cancerous tumors on the membrane from
which they selectively bind. [A: 57: 179-180] They also allow
other harmful substances to act more selectively on cancer
cells. Thus, the male hormone used against breast and uterine
cancers causes less facial hirsutism and hoarseness of voice.
[A: 61-62]
Synthetic physiatrists are used to prevent tumor development, to
reabsorb, to operate, and to prevent metastasis. [A: 49] They
also allow the patient to reduce his suffering [A: 54], but also
to resume his bad habits, thus compromising his chances of
recovery [A: 51].
On March 4, 1948, he made a communication on his procedure to
the French Society of Microbiology, published in the "Annales de
l'Institut Pasteur". [A: 59]
In May 1949, for acts of resistance during the war, he acquired
French nationality. [A: 100 & 188]
At the end of 1949, he learned that his father had a huge liver
tumor. He sends Famagusta iodized distillate of cod liver oil in
solution [A: 90] giving advice for treatment and injection.
Doctors are amazed to see the tumor disappear in three weeks [A:
91].
The news aroused jealousy at the Pasteur Institute, where it was
reproached for its zeal in work and its experiments on glycerin,
proving that artificial immunity was transient, and which
questioned the usefulness of vaccinations which constituted The
majority of the resources of the Institut Pasteur. [A: 91-92]
Louis Aublant, Secretary General of the Pasteur Institute, asked
him to leave. [A: 92]
He is hired by the Institut Gustave-Roussy de Villejuif
(specialized in cancer), by Professor Charles Oberling, and
licensed from his first experimentation, after three weeks. [A:
93-95]
He is refused the service of Professor Raoul Kourilsky,
specializing in tuberculosis at the Saint-Antoine hospital; At
the service of Dr. Jean-Paul Sisley, of the Laboratoire des
Corps Gras de Bellevue; At the service of Dr Chadourne, director
of the sanatorium of L'Haÿ-les-Roses; At the service of
Professor Aubel. It is written to him, strangely seen his
diplomas, that we have enough lab laborers. His wife, Michelle,
suspected that the Pasteur Institute was blocking his career,
telephoned the successor of Dr. Van Deinse to the head of the
tuberculosis department, posing as the director of a laboratory
that wanted to know what " He thinks of Solomides who has just
presented himself to her: "Oh, you know, he never broke three
legs to a duck," he replied. [A: 95-96]
He was informed that he was dismissed from the CNRS in June 1950
with six months' notice, without being able to receive him. The
president of the CNRS finally writes that he can not reveal to
him under what conditions the Commission of the medicine decided
its dismissal. [A: 97]
He treats a neighbor with a stomach cancer, whom a surgeon,
after opening, has closed again without operating because of the
size of the tumor. [A: 96-97]
He installed his laboratory in the cellar of his pavilion at
Sceaux, 13 rue de la Marne, with the help of a doctor who lent
him 30,000 francs.
Because of his successes, five to ten patients a day present
themselves. [A: 98]
Having advised a patient not to carry out an operation, the
surgeon has him summoned by the county council of the Ordre des
médecins. Solomides not appearing in his disciplinary committee,
the council complains about the illegal practice of medicine.
[A: 102]
He is summoned by the investigating judge Ferdinand Gollety and
the police raided his home. [A: 103] In 1953, an amnesty ended
the case with a dismissal. [A: 104]
On March 13, 1951, he made a communication to the Society of
Comparative Pathology on some aliphatic (hexanal, heptanal,
octal and citral) aldehydes (alcohols dehydrogenated) as a
treatment for eczema and analgesics in cancer. The president of
the company, M. Gastinel, Professor of Microbiology, goes on to
say that it is impossible to cure eczema and especially cancer.
Dr. Grillot, the company's secretary, said: "You were
unanimously elected as a Correspondent of the Society of
Pathology." A month later, a letter informs him that his
communication can not be published, and he sends his
resignation. The paper is published by a medical journalist who
attended the 1951 session of the Journal of the American Medical
Association under the title "The therapeutic applications of
œnanthol". [A 107]
In 1951, "La France médicale", which had published its previous
communications, refuses to do so, as well as "Nature" in
England, "Experientia" in Switzerland, for lack of space. [A:
108]
In 1951 and 1952, he obtained marketing authorization for
Citral-Urethane and Geranyl, two oils of plant origin with
ether-oxide of olyethylene glycol. Visas were obtained in six
months, against bronchitis, eczema, allergies, as analgesics in
cancer. The Geranyl was experimented in Villejuif. A small
laboratory, Biostabilex, operates visas until 1972. [A: 105]
From 1952, he decided to publish the "Annual Review of
chemotherapy and prophylaxis of cancer" which will make it known
by many doctors. [A: 109: 110]
In 1952 and 1953 he wrote to the French National League Against
Cancer in order to ask for a subsidy which he refused, since it
would enable him to provide free ampoules of synthetic
peroxidases for testing in their services. [A: 108-109]
On 19 December 1954, at a press conference given at the Essec
Prize, founded by the Catholic Institute and the French League
against Cancer, in order to encourage young researchers,
Solomides was surprised at the lack of curiosity The Institut de
Villejuif with respect to its medicines which, in some cases of
cancer, give good results and which always lead to sedation of
pain. Professor Pierre Denoix, director of the Gustave-Roussy
Institute in Villejuif, replied that he was embarrassed but
polite, that we could talk about this elsewhere. The Abbe
Donjon, director of the Catholic Institute, did not let
Solomides leave the room. As there are journalists, and in
particular Jacques-Louis Tissier, President of the Union of
French Journalists and Foreign Press Correspondents, who asks
for explanations, a conference is organized on 24 February 1955
for the learned societies. A half-dozen patients came to
testify. The next day, Georges de Caunes invited him to the
radio-television studios with two or three patients. [A: 114]
From then on, a cohort of patients telephoned him, wrote him,
waited in front of his house for tens of meters, in order to try
a much less mutilating treatment. [A 117]
The Ordre des médecins asked the Radio-Télévision to no longer
communicate the address of Solomides to the patients who
requested it: they had to be directed to Curie, Villejuif, the
Hartmann Center. The President of the Order, M. Piédelievre, who
had passed the examinations to Solomides, having granted him the
diploma of doctor of medicine, reminds television that there is
no cancer treatment other than surgery And radiotherapy. [A:
117-118]
In April 1955, the Official Bulletin of the Chamber of Medical
Officers of the Seine (no. 4) published an article entitled
"French Radio-Television in the service of charlatans". [A: 118]
Solomides assigns the ballot for defamation claiming ten million
francs in damages. [A: 120-121]
Pushed by the Trade Union Chamber, the Ministry of Public Health
files a complaint in illegal practice of medicine and another
for illegal practice of pharmacy. [A 121]
Two police inspectors are sent and Solomides is reconvened by
the investigating judge Gollety, with whom he becomes a friend.
[A 121]
In Belgium, the drug is tested and reimbursed by the Social
Security. [A: 126]
A large Cuban laboratory pays a million francs for research
expenses, requests a contract to have exclusivity for South
America, and then ceases to show when Cuban officials have
requested information from the Institut Pasteur. [A: 126-127]
On January 31, 1956, Solomides gave a lecture on synthetic
peroxidases, with many patients healed, at the Sorbonne
Geological Amphitheater. [A 129]
On April 12, 1956, the conference, which was to be the occasion
to publish a pamphlet presenting a hundred new cases of cures,
scheduled for April 14, 1956 at the same place, is, according to
M. Pérez, dean of the Faculty of Sciences of Paris, By the
Ministries of National Education and Public Health, on the
intervention of the National Order of Physicians. In fact, a
junior public health official communicated the prohibition to
the dean without a ban on both departments. The conference is
made before the learned societies. [A: 129-130]
In October 1956, Solomides published an outreach journal,
"Victories on Cancer," and created the World League for Cancer
Chemotherapy. [A 131]
Of the patients sent home by oncologists who could do nothing
for them, Jean Solomides saved 14%; On those who follow his
treatment before any other, 70% are cured, double the
conventional treatment. In fact, by reacting surface antigens on
cancer cells, synthetic physiatrists added to chemotherapy
increase efficacy by 30% [B: 41].
- On January 24, 1957, the trial began at the 16th Correctional
Chamber of the Seine, under the presidency of Mr. Mille.
Solomides, a victim of a heart malaise, is defended by Mr.
Hayot. [A: 134] Testify Mr Brillault, president of the civil
court in Bordeaux, and a young sales representative with
laryngeal cancer who were able to preserve their voice without
surgery or radiation therapy. This allowed Mr. Brillault to
chair new hearings. Dr. Boisseau, former director of the Pasteur
Institute of Brazzaville, then of the Pasteur Institute of
Athens, retired physician colonel, and then head of microbiology
department at Rhone-Poulenc, commander Of the Legion of Honor,
testifies that one of her relatives, who must have died of a
breast tumor for two years according to the diagnoses of the
specialists, is in good health thanks to the medicine of
Solomides [A: 136- 137]. Dr. Mamonni, a treating physician,
testified that he had rescued his twenty-year-old niece,
condemned according to Curie surgeons, and said that, in
addition to the increase in cures, Use of morphine. He adds that
a physician who is aware of the Solomides treatment and who
refuses to try it is a criminal. [A: 137]. M. Mignon deposited a
copy of the letter of Professor Denoix, in which the director of
the Gustave-Roussy Institute pronounced the death of his wife in
the near future; And a duplicate of the letter of Dr. M. of the
Foch Foundation, in which he affirms two years later that the
intestinal tumor has disappeared [A: 139]. According to article
63 of the Penal Code, Mr. Hayot pleads the obligation to
rescue persons in danger [A: 141]. On January 31, the court
sentenced Solomides to a minimum of 10,000 francs for
conditional fines because he noted the cure of cancers that
allowed Solomides to benefit from "the broadest extenuating
circumstances"; And the accusers only benefit from 1 symbolic F,
and not from the 500,000 and 100,000 francs they claimed. The
medical bodies appealed, and the trial of 9 June 1960 confirmed
the first judgment. [A: 141-142].
On October 10, 1957, the unlawful trial of pharmacy was pleaded,
as only three of its synthetic physiatrists obtained the visa
from the Ministry of Public Health [A: 148, 151]. Solomides
explains that he obtained the visas as long as it was eczema and
bronchitis, but not for cancer, because of the partiality of the
Gustave-Roussy and Curie institutes, and the absence of
counter-expertise [A: 152]. He refers to the reimbursement of
the SPs in Belgium, their authorization in Switzerland and for
two days in Greece [A: 153]. Baroness Héraud quotes Professor
Oberling's letter, which states that "the ideas of Solomides do
not correspond to the present state of science" so as not to
involve him in Villejuif, and the letter of Dr. Lavedan, head of
the department Anti-cancer drug of Curie, which says without
explanation that all the leaders of the anti-cancer centers
refuse the request for subsidy made by Dr. Solomides,
unanimously and in the name of the French National League
against cancer [A: 154] . Expertise is sought [A: 154]; Some
experts recuse themselves; The results are published after two
years and the illegal trial of pharmacy continues in February
1961 [A: 157].
- Laboratory G ..., producer of the male hormone against breast
cancer, refuses to produce its medicines to obtain a visa
because it fears that its sales fall because of the opinion of
doctors of the major centers. Solomides decides to create his
pharmaceutical laboratory, Sceaux-Pharma, in order to obtain the
visas [A: 160]. On November 24, 1957, Solomides inaugurated his
institute near his home, in the presence of Van Deinse, his
former teacher, Boisseau, former director of the Pasteur
Institutes of Brazzaville and Athens, many doctors; A Greek
delegation led by Dr. Katsafados, chief surgeon of the Tzanion
Hospital in Piraeus, President of the Anti-Cancer Centers of
Greece, deputy, former Minister of Public Health, and Dr.
Katsaniotis, Director of Public Assistance of 'Athens; A Belgian
delegation led by pharmacist Tack who heads the Solomidès
Institute of Belgium. [A 148]
His World League for Cancer Chemotherapy becomes the sick Human
Rights League, and the magazine "Victories on Cancer becomes"
Remedies-News "[A: 161]
In November 1958, stress caused a relapse of intestinal
tuberculosis which he had in his youth. [A: 162] He is being
treated with the Friedmann vaccine, the only curative vaccine
and the most effective vaccine against tuberculosis, used in
forty-six countries and not authorized in France [A: 163].
On July 23, 1960, representatives of the judiciary searched at
Sceaux. [A 163]
On February 2, 1961 the trial for the illegal practice of
pharmacy resumes [A: 167]. Solomides challenges the accusation
that he does not manufacture standardized "proprietary
medicines", but "secret remedies" in the course of
experimentation, without the control of a pharmacist, as is the
case at the Institut Pasteur . The iodized PS, PS 4A for
example, is a progress, and of all the formulas tested, only a
dozen have been conserved, against five diseases: cancers,
multiple sclerosis, asthma and eczema. [A: 168, 305] He rejects
the report of the five experts who selected only 26 of the 80
cure cases. They deny any benefit of the PS, conclude to
misdiagnosis made by specialists like Pr Delarue and Pr Brux
whenever healing is impossible with the conventional treatment,
or they claim that a biopsy could heal the whole Cancer; They
attributed, for example, the cure of Nicol's uterine cancer to
curettage which was not a biopsy [A: 170-172]. The experts are
absent and there are no prosecution witnesses [A: 173]. Several
testimonies and diagnoses prove healings which were made without
the amputations (legs, breast) prescribed by classical medicine
[A: 174; 183].
At the second hearing on 9 March, the experts did not want to be
present [A: 186].
At the third hearing on April 27, the suspicion expressed
scandalized loudly of sick patients and Michelle Solomides who
was expelled. [A: 187-193]
The verdict of May 25 does not recognize extenuating
circumstances: the sentence is of 10,000 new francs in fine,
2,000 francs to the civil parties, plus costs [A: 194].
Four trials will follow, leaving Solomides without prosecution
until a few months in 1975 [A: 200].
Having renounced his own illness in 1963, Solomides urged Dr.
Persâtre, who was accused by the College of Physicians of
violating section 21 of the Code of Conduct, because he would
give consultations in commercial premises, and He was sentenced
to one year's suspension of the right to practice medicine [A:
203]. Having opened a dispensary outside his institute, along
with Drs. Persâtre and Nahon, another police search took place
on June 2, 1965, prompted by a new complaint from the Ordre des
médecins. Patient records and visa applications are seized. [A:
204] The two doctors are also prosecuted under Article L-372 of
the Public Health Code for illegally practicing medicine for
working with Solomides and for illegal practice of pharmacy for
prescribing PS; But none of the other prescribing doctors whose
letters were seized, including Dr. Albert Schweitzer (Nobel
Peace Prize), was prosecuted [A: 205-207]. Persâtre is struck
out for life and Nahon suspended for two years [A: 208]. Nahon
is also sued for "non-personal advertising" for publishing in
the "Remedies" review observations on PS cures in patients
deemed incurable, as if it were prohibited by the Code of Ethics
for physicians to publish his observations in Of medical
journals [A: 208]. Nahon went abroad and Persâtre became a
medical visitor and died of despair before the 1972 trial. [A:
210] The Presidents of the League of Human Rights Sick, MM.
Ayoul and Massiou [A: 210] are prosecuted for illegal practice
of pharmacy, and the association is dissolved. * The Scout
Center for Biological Research (CSRB) is created so that
Gustave-Roussy or Curie do not own it. [A: 216] Inaugurated on 7
May 1965 to support the application for visas through care and
clinical trials, the Jean-Jaurès Street medical center closed on
1 September 1966 [A: 216]. On April 4, 1968, the court
acknowledged the argument of the CSRB counsel sought to
dissolve, alleging that the center was blamed for being illegal,
whereas his activity was precisely to obtain an authorization Of
medicines. [A 216]
- On 15 December 1955, Solomides signed a contract with a
Belgian shipowner, Oïdtmann, [A: 220] who at the 1955 press
conference understood the value of synthetic peroxidases and
claimed to obtain Belgian pharmaceutical visas quickly To its
relations [A: 218]. On December 21, 1961, Oïdtmann filed a
complaint for fraud, with as a lawyer, Mr. Piédelièvre, the son
of the President of the Order who stated on television in 1955
that only surgery and radiotherapy were effective against cancer
[ A: 219]. Solomides was heard by the police, then by Justice
Perez in 1962 [A: 219]. On October 26, 1966, five years after
the complaint, Roussel J. charged him in this case [A: 220]. The
investigating judge and the prosecutor, Mr Tachella, unlawfully
added to the file the findings of the appraisals and amnestied
verdicts in February 1962 [A: 219], because they found no expert
who wanted to sign a false report; Mr. Tachella writes: "In view
of the difficulties encountered by the investigating magistrate
in the search for experts, those who have been sought by the
judge recusing alternately, the civil party then decides to
admit to the case file two reports submitted in other
instances." [A: 221].
In 1967, Oïdtmann died; His family is persuaded to resume the
complaint [A: 226]. At the first hearing before the Twelfth
Correctional Chamber on November 25, 1969, Solomides' counsel,
Mr. Beyssade, pleaded the limitation period, which the court
held in its verdict of January 13, 1970 [A: 222-223]. The
prosecutor appealed, which took place on 14 November 1970 before
the Ninth Chamber of the Court of Appeal [A: 223].
The Advocate General, who admitted the limitation period for the
first three years, asked whether there were any fraudulent acts
after 1958. [A: 223] With the agreement of the Court of
Cassation, experts Roger Le Breton and Pinta can testify. [A:
223]
On 30 January 1971, the case was finally decided on the merits.
Solomidès proves with false experience that the experiments were
false [A: 223-224]
Me Piédelièvre considers that the sending to Oïdtmann of the
"Annual Journal of Cancer Physiotherapy and Chemotherapy" and
"Victories on Cancer" was a fraud for Mr Pasturel, considers
that there are some very interesting articles, in particular one
by Dr Katsafados, former Minister of Health in Greece. [A: 225]
Pasturel insisted on the very advantageous conditions for
Oïdtmann in order to launch the PS, and he abandoned the
accusation, which he had asked to be tried on the merits.
Piédelièvre protested [A: 225]. President Fonade said to
Solomides: "I knew you already in the press, because a few years
ago, we were a renowned but contested personality, it was at the
time of your trial and I apologize for alluding to Amnesty
trials, and I must admit that most of the articles were
favorable to you. " [A: 226]
Mr. Beyssade argued that even if Solomides had been mistaken
about the effectiveness of the PSs, there would be no scam
because there is neither staging nor intention to deceive. The
verdict of 20 February 1971, the innocent Solomides of fraud and
charlatanism, acknowledges the prescription and condemns the
Oddtmanns to the costs [A: 226].
On February 12, 1964, scandalized by a severe judicial verdict
and then by the banning of a lecture by Dr. Müller on the life
of Solomides, a few hundred people try in vain to be heard by
journalists of the Figaro, Ministry of Health, where a
delegation is rebuked. [A 272]
- On April 20, 1964, Solomides organized a press conference
where many journalists listen to the testimonies of the sick and
half a dozen doctors, Solomides asks. Very few publications
follow, as editors do not want to take risks. The article of the
editor of the Central Press Agency appears only in the review of
Solomides. [A 268]
- After the easy authorization to open Sceaux-Pharma in 1962,
the renewal of the authorization scheduled for February 1964 did
not arrive. After three years of numerous written and telephone
requests, on July 7, 1967, the Ministry of Public Health
justified a refusal to open an opening due to incomplete
equipment and lack of capable personnel. The laboratory was
therefore closed until 17 March 1970, when the Ministry,
recognizing its abuse of power, gave its authorization while the
complaint brought by Solomides against the Ministry of Public
Health was to be presented before the Paris Administrative Court
[ : 212].
On 8 July 1970 the Administrative Court found that there were
anomalies within the time-limit and that the contested decree
was not legally justified because it was based on materially
inaccurate facts. [A: 213] Although the State Is ordered to pay
the costs, six years have been lost for applications for
marketing authorizations [A: 214].
- In 1965, the PS 88 is validated by the chemical and
toxicological expertises. [A: 228] In 1970, Sceaux-Pharma
reopened [A: 228] but did not produce anything, as it threatened
closure if it produced drugs without a visa [A: 231]. Its
leaders are seeking an expert for a clinical trial that would
validate a visa. The first, who is slow to agree, refuses by
saying that his hospital department does not have the favorable
conditions for the experimentation to be valid. A second expert
undertook satisfactory tests, acknowledged that he often
achieved spectacular results, but refused to sign his expert
report, because of the problems it might cause him with the
Department of Public Health. In March 1972, a third expert,
hospital chief in the north, was met by Solomides and Pierre
Landrin. 25 out of 50 patients should receive the drug, but it
does not do the experiment [A: 230-231]. Since experimentation
is mandatory on at least 100 patients, fewer hospital services
can perform the tests; And the hospital chiefs are afraid of
losing their renewable mandate every three years and displeasing
the ministry [A: 231].
- In June 1969, Irwin S. Morse, surgeon at South Miami Hospital,
and Paul O. Nees of the Biological Section of the Wisconsin
Alumni Research Foundation, published at the Sixth European
Congress of the International College of Surgeons (FIC) By
excision of the tumor after treatment and reduction to the
physiatrons. Experimentation in necropsied rats afterwards
revealed no significant toxicity. On spontaneous breast tumors
of the dog, with four veterinarians: Drs Austin, Boyd, McMillan
and Mueller, they observe reductions in tumor size. [A: 48-49]
- In the 1970s, one month of Solomides treatment costs 70 to 200
F, the most expensive being injected by intravenous injection,
while one month of treatment with nine ampoules of Bleomycin
costs 1200 F; One month of Endoxan alone used costs 800 F, and
half less associated with another; Triamcinolone (cortisone)
costs 200 to 600 F per month, and prednisone (cortancyl) about
80 F, but they are generally not used alone. Often avoiding
hospitalization, Solomides treatment saves 75 to 750 francs per
day of hospitalization. By avoiding operations, it saves the 800
F of an operation of a cancer of the uterus and the 2,000 F of a
stomach cancer operation, besides the adjuvant drugs and the
radiotherapies which can To reach 10,000 F. A dose of 60 mg
radium for brachytherapy costs 7,200 F. And often these
treatments are often used palliatively, with no hope of
recovery. [A: 255-257]
- In the weekly Paris-Match, Professor Oberling unveils a
picture of his tools against cancer, among which is the
Citral-Urethane, whose inventor is Solomides. [PS: 106] PS 120 C
is a little toxic, due to TEM diluted to 1 / 36,000 in it, but
is reserved for the treatment of leukemia and Hodgkin's disease
(3% of cancers). [A: 70] The Geranyl Biostabilex of Solomides is
in the Vidal.
- In April 1972, the Regional Accreditation Commission wrote
about the clinic, which was judicially closed: "Since the report
of the investigation established that the center was closed, the
Commission considered that it could not examine this file
because The dispensary should have been opened without
permission to be allowed to open, but then would not it have
been closed yet to be opened without authorization? [A 217]
- On November 3, 1972, in front of the 17th Correctional
Division of Paris, Mrs. Mathieu Laurent testified that in 1965
she was diagnosed with breast cancer and proposed the removal of
a breast. She preferred to be prescribed by Dr. Jacques Nahon of
synthetic physiatrists, which allowed her to retain her breast.
Madame Yvette Lefèvre gave a similar testimony, also cured by
having kept her breast. [A: 34-35]
- On 24 May 1973, before the 11th Chamber of the Paris Court of
Appeal, Mrs Janine Picaud, of Andrésy, testified that her
18-year-old son Jean-Pierre was operated on 24 November 1970 at
the Lariboisière hospital , To the brain for a right temporal
cancerous tumor. The prognosis is "serious in the short term".
Jean-Pierre undergoes two daily bites of cortisone. On 28
February 1971 he entered a coma. On the 10th of March, Dr. T.,
consulted at Lariboisiere, said to his mother, "If there was
anything, we would tell you. We warn you that there is nothing
to be done." The next day, the mother went to see Dr. Solomides,
whom an ambulance attendant had given him the address at the
first transport of his son to Lariboisiere. It receives for two
months ampoules of PS 300 in injections. Jean-Pierre is
recovering. The physician in charge of performing Lariboisière's
treatment was not authorized by the Departmental Council of the
Ordre des médecins to testify to the beneficial effect of
synthetic physiatrists [A: 37-39].
The judgment of 14 June 1973 of the 11th Chamber of the Court of
Appeal observed that the results obtained with the physiatrons
of Jean Solomides were "indisputable" [A: 82].
On 28 December 1976 three days before the European law of 1
January 1977 which recognized the equivalence of certain
diplomas and allowed Solomides to lawfully practice medicine on
condition that he declared on his honor not to be charged, He is
summoned to the Palais de Justice as a matter of urgency, which
prevents him from making such a declaration. Absent from Paris,
he hardly gets a postponement until January 10, 1977, where he
undergoes an interrogation he refuses to sign. The examining
magistrate considers it unnecessary to refer to the European law
"when one has a good French law". [A: 234-235]
- On the television show Apostrophes of 14 October 1977, before
the doctor Henri Pradal, the oncologist Léon Schwarzenberg
treats solomidès de charlatan. On the issue of 4 November 1977,
presenter Bernard Pivot read a right of reply from Solomides
[D].
A radio broadcast of Anne Gaillard to be held on 14 January 1978
between Jean Solomidès, Henri Pradal and André Conord to Prs
Georges Mathé, Léon Schwarzenberg and Étienne-Émile Baulieu, A:
290-291].
When Solomides asked to be registered with the departmental
council of the Hauts de Seine Medical Order, the latter refused
to do so by invoking past prosecutions, wrongly because they
were amnestied. The regional council and the national council
also refuse. [A 295]
- Dr. Bocquet, a biologist, publishes in the Bulletin de
l'Académie Vétérinaire de France a demonstration of the action
of synthetic physiatrists on immunity, by selectively
suppressing B lymphocytes, those which produce protective
antibodies to tumors [A: 305, 333].
- On November 20, 1978, Solomides made his eleventh appearance
before the judiciary for the illegal practice of medicine and
pharmacy. [A 295]. Professor Verhaegue (of Lille) and Jean
Bernard are witnesses to the Medical Association, without being
informed, Mrs Carnet, Solomides' lawyer who believed that the
case would be judged on the law, not on the merits .
Consequently, he did not call any patient or doctor as a
witness, but Sauveur Calabria, president of the League for the
priority application of Article 63 of the Criminal Code for the
Patient at Risk (LAPA 63). Prosecutor Lazari promises to review
the law only several times, which he does not do [A: 296,
305-306]. Similarly, Jean Bernard severely criticizes the
treatment of Solomides by asserting that they were not cancers,
otherwise they would not have been cured [A: 298].
Yet, in "Victories on Cancer" of October 1957, p. 8, describes
the case of a leukemic child with generalized
lymphosarcomatosis. Professor JB told his parents that he had
only a few weeks left. Dr V. prescribes peroxidases. The child
heals and the parents will inform Professor JB who, to their
amazement, says to know the treatment Solomides who would get
80% cure. [A: 297-298] In the courtroom, Professor Jean Bernard
says that it is "to try all new therapeutics, whatever they may
be, and if they are valid, their effectiveness is revealed
before five or six years Mr. Solomides is not. " Yet, although
he has been an influential member of the Academy of Medicine for
many years, he has not asked for any experimentation [A:
302-303]. Professor Verhaegue admits that the Solomides
treatment reduces the inflammation and the volume of the tumor,
but regrets the silence of the patients aware of the threats.
[A: 303-304]
On 18 December 1978, Solomides was sentenced for the illegal
practice of medicine and pharmacy, to the maximum of the fine,
and especially to close his institute. While Jean Solomides
appeals, some twenty patients march in the Palais de Justice,
shouting "Order of physicians, assassin" [A: 308].
The Committee for Cancer Defense and Information (CDIC) was
created and published on January 20, 1978 in "L'Impatient"
(Solomidès, c'est la guerre). In two months, there are 1,000
members. On 28 March 1979, on the suggestion of André Campana, a
television writer and journalist, he published an "Appeal for
the experimentation of medicines developed by Jean Solomides": a
full page of 350 signatures in The daily "Le Matin de Paris"
including that of 170 doctors, about thirty elected officials,
journalists, trade unionists, artists. After the ad service of
the World "agreed to publish it, its medical columnist Dr.
Claudine Escoffier-Lambiotte refused to publish it. In an
interview with" Paris-Match ", Professor Lucien Israel attacks
Dr. Solomides, and none Right of reply is published. [A: 287,
309, 312]
On April 27, 1979, an inquiry was made in Paris-Match No. 1561,
where Professor Lucien Israel asked: "Do you trust this
gentleman who claims to have found a miracle cure for cancer in
his back kitchen for thirty years? ", While he made his
discovery at the Institut Pasteur. He said: "A few months ago, a
couple of weeks before he went to trial, his son who works with
him came to me and asked me to test the drug in the man.
Judgment as if it were a possible thing, it takes twelve or
eighteen months to get serious results. " The judgment, on
December 18, 1978, preceded the visit of Jean-Michel Solomides,
which occurred in January 1979. [A: 318-320] Jean-Michel
Solomides writes a short letter that is truncated in
Paris-Match. On May 12, his father demanded a corrigendum. [A
322]
In Le Monde on March 31, 1979, Dr. Charles Proux, who headed the
radiotherapy unit at the Tenon Hospital, said that "the patients
felt better, they regained some energy, but there was no cure
and No direct effects on tumors. " But even an analgesic effect
should have caused the greatest interest, since Professor Léon
Schwarzenberg, at the Entretiens de Bichat 1979, advocated to
reduce the suffering of terminal cancer patients by injecting a
mixture of drugs such as alcohol (ethanol ), Heroin and
morphine. [A: 315-316, 333]
- Solomides falls ill with pulmonary congestion, is alighted on
May 12, and dies on May 28, 1979. [A: 288, 322] About fifteen
thousand patients were treated [A: 323].
- On 28 July 1983, the Regional Directorate for Health and
Social Affairs of Île-de-France brought an action which resulted
in a search of the premises of the Institute on 15 January 1985,
with seizure of the material used to manufacture Solomides
products .
- Following a report sent to the public prosecutor's office in
November 2006, on 3 June 2009, Messimy's laboratory, located
some twenty kilometers from Lyon, set up by the Choisis la Vie
association since 1985, is invested by gendarmes (OCLAESP),
headed by Colonel Thierry Bourret, acting on a letter rogatory
of a judge from Marseille. Nine persons are held in police
custody and charged.
Jean
Solomides and Mirko Beljanski
Solomides and Beljanski having been colleagues at the Institut
Pasteur for a little more than a year from 1948 to 1949, I
wondered what Beljanski thought of Solomides. At the CIRIS
General Assembly in 2002 or 2003, a collaborator told me that
Beljanski thought that Solomides was a charlatan. This was
confirmed to me in 2009 by Dr. Jean Lacaze, who told me that he
had received a letter from Beljanski, in which he reproached him
for associating it in a writing with the "semi-charlatan"
Solomides ...
It is also remarkable, in one of the ironies of history, that in
Confiscated Health (1989, pp. 135-136), the Beljanski couple
reported that they had sought in vain for support from the
scientific advisor Of the Minister of Research, Jacques
Benvéniste, and that he also found himself a few months later to
the ban of the scientific community, for having made the
heterodox discovery of the "memory" of water ....
http://lachainedevv.com/produits-solomides-sclerose-en-plaques-cancer-un-traitement-interdit/
Products Solomides, multiple sclerosis,
cancer, a prohibited treatment.
By Vévé
In the 1970s, Dr. Jean Solomides launched a miracle cure for
cancer: physiatrists. Treatment decried by some, miracle
solution for others, this drug was removed from the market. Back
on testimonials from a doctor and some patients ...
Distribution of illegal drugs: from the conditional prison in
Marseille
Conditional sentences of six months to one year were required on
Thursday against five people who appeared in Marseille for
manufacturing and distributing illegal and sometimes dangerous
medicines via an association, it was learned from Of the
lawyers. The court of correctional of Marseilles has made its
decision under deliberation to May 15, indicated Me Olivier
Saumon, attorney of the National order of the pharmacists, who
had been civil party in this case.
Five people, including two pharmacists and a doctor, and the
"Choisis la vie" association are being prosecuted for making and
distributing illegal drugs that were prescribed to people with
cancer or multiple sclerosis.
Robert Gaillard, president of the association "Choisis la vie"
and his wife Christiane, are accused of illegal practice of
pharmacy, deception and endangering the lives of others.
The prosecution demanded six months' suspended prison sentence
for the Gaillard spouses, one year suspended and two years of
prohibition against the two pharmacists and one year suspended
with one year's imprisonment. Prohibition against the doctor.
He applied for a fine of 10,000 euros against the association
"Choisis la vie". Founded in 1985 and based in Messimy (Rhône),
this association broadcast "Solomides" products, named after a
doctor who died in 1979 The range of drugs "Vita", supposed to
fight against certain degenerative diseases.
The medicines, which were not granted marketing authorization,
were presented as a side-by-side therapy to help patients deal
with the disease, which the association also offered listening
and psychological support.
The survey began in 2006 when the Pharmacovigilance Center in
Saint-Etienne alerted the French Agency for the Safety of Health
Products (Afssaps) on the delivery of medicines without a
marketing authorization to a young woman suffering from Multiple
sclerosis. This patient, suffering from pneumocystosis and
severe lymphopenia, had to be hospitalized in emergency
resuscitation.
The investigation led to the dismantling of the laboratory where
the products were manufactured.
Some products in the Vita range contained substances with
significant carcinogenic risks, such as urethane.
http://www.luc-bodin.com/2011/01/22/les-produits-solomides-contre-le-cancer/
Solomide Products vs Cancer
Solomide products, synthetic physiatrists or peroxidases have
been used for years against certain cancers, including cancers
known to be serious and serious, such as cancers of the brain,
lung, leukemias and others. In spite of this, the laboratory
which has been officially manufacturing and selling Solomides
products for many years in France has been "dismantled" by the
Gendarmes of the Central Office for the Fight Against
Environment and Public Health, thus depriving The sick of many
interesting remedies.
It should be remembered that Dr. Solomides, a graduate of
science, a former researcher at the Pasteur Institute, invented
synthetic physiatrists or peroxidases (PS) in the 1950s, with
which he began by curing his father with a Cancer of the liver
in terminal phase. The principle of these remedies is that
distilled and solubilized oil of cod liver would bring oxygen to
the cancer cell, which would seriously harm it, because it lives
in anaerobic (in the absence of oxygen). The PS have
demonstrated efficacy against certain severe cancers such as
gliomas (brain tumors with very poor prognosis), bronchial
cancers, certain inoperable meningiomas, leukemias including
myeloma ... but also multiple sclerosis, viral hepatitis,
ulcerative colitis Hemorrhagic, etc. These products did not
present themselves as alternatives to conventional treatments,
but as complements, thus giving hope where they were no longer
available.
However, as is often the case in natural medicine, studies on PS
were rare and limited in number of cases due to a lack of
financial resources. However, numerous testimonies attest to the
soundness of the method. So, instead of banning and seizing
these remedies sold for more than 50 years, perhaps it would
have been more judicious for the sick, to seriously study their
therapeutic effects? Because modern medicine is only of very
limited efficacy against gliomas, lung cancer, multiple
sclerosis, viral hepatitis ... So the "discovery" of a
complementary treatment would not have been superfluous ...
Dr. Luc Bodin
PATENTS
GB1077683
Improvements
in or relating to the preparation of organic iodine
compounds with therapeutic properties
The invention
comprises an iodohydrin of a water-soluble tris-(polyoxyethylene
ether) of castor oil complexed with an iodide and iodate of an
alkali metal or alkaline earth metal which is prepared by
reacting an alkali or alkaline earth metal hypoiodite with a
water-soluble tris-(polyoxyethylene ether) of castor oil. The
products may be dissolved in water or urethane water.ALSO:The
invention comprises an iodohydrin of a water-soluble
tris(polyoxyethylene ether) of castor oil complexed with an
iodide and iodate of an alkali metal or alkanine earth metal
which is prepared by reaction of a watersoluble
tris(polyoxyethylene ether) of castor oil with an alkali or
alkaline earth metal hypoiodite.ALSO:Pharmaceutical preparations
comprise an iodohydrin of a water-soluble tris(polyoxyethylene
ether) of castor oil complexed with an alkali metal or alkaline
earth metal iodide and iodate together with a pharmaceutically
acceptable carrier and/or diluent. The preparations are
anti-carcinogenic.
The present invention relates to organic iodine compounds with
therapeutic properties.
According to this invention we provide a process for the
preparation of an organic iodine compound with therapeutic
properties in which process an alkali metal or an alkaline earth
metal hypoiodite is reacted with a water-soluble tris
(polyoxyethylene ether) of castor oil (ERP), to form an
iodohydrin of ERP complexed with an iodide and an iodate of an
alkali metal or an alkaline earth metal.
According to a feature of the present invention potassium
hypoiodite is used as the mineral hypoiodite.
According to another feature of the invention, the reaction is
carried out with agitation.
As a new medicine, particularly for use in the treatment of
tumours of cancerous origin, the invention covers an iodohydrin
of ERP complexed with an iodide and an iodate of an alkali metal
or an alkaline earth metal.
It appears that the reaction between the hypoiodite and ERP
involves a peroxide effect with an acid reaction which
neutralises the strong alkalinity of the mineral hypoiodite by
liberating hypoiodous acid (I011) whidh fixes on the double bond
of the treated organic compound. Iodine derivatives and
iodohydrins are then formed.
It is not possible to prove the presence of [Price 4s. 6d.]
peroxide either before or after hypoiodation and it is not yet
known by what mechanism the p11 of the hypoiodite falls to
values in the region of neutrality.
The process for the preparation of the new iodine derivatives in
accordance with the invention comprises two phases:
(a) Prepamition of tho potdirsium, hypiodite grs of potash
tablets and 50 grs of iodine sublimate are brought into contact
in a crystalliser or a litre flask (balloon type); a litre of
distilled water is then added in small quantities with constant
agitation. A yellowish liquid having a very strong iodoform
odour and a very alkaline pH is rapidly obtained, in one or two
minutes. No precipitate remains and there is no trace of
undissolved iodine.
(b) Hypodisation of ERP The litre of potassium hypoiodite
solution, prepared as stated above, is immediately mixed by
stirring with two litres of ERP. A small amount of heat is given
off and this raises the temperature of the mixture to
approximately 350C to 400C; it is followed by a progressive
reduction of the pH which passes from 12 to 13 to approximately
7.5 by a mechanism which still remains obscure, since the ERP is
not an acid substance (pH 6.5-6.8 in a 10% solution in distilled
water).
The resulting product is soluble in water, and is very soluble
in urethan water. By simple acidification it liberates Wodine,
it also liberates iodine in potassium iodide solutions,
acidified by acetic acid, but does not discolour indigo blue as
does the mineral hypoiodite for its pH is neutral.
Physico-chemicad chkracteristics Non-ionic surface active
agents, of which ERP forms part, have the basic property of
separating 2 1,077,6S3 in aqueous solution and at temperatures
above 40'C into two layers: a lower layer formed of the
non-ionic detergent and an upper layer formed of the solvent
which in this case is water. However, it has been discovered
that the product of the hypoiodisation of ERP in solution in 15
to 20%' of water, does not become cloudy and no longer separates
into two layers whatever the temperature to which it is raised
(even 1O00GC. All the test solutions of ERP alone, or associated
with potassium iodide, potassium iodate or both together, become
cloudy and separate into two layers at approximately 60 whatever
their pH (neutral, acid or alkaline). One concludes that the
potassium iodide and the potassium iodate formed by dissociation
from the hypoiodite according to the reaction: 3KIO= KI03 +2 KI,
are not sufficient to confer upon ERP such remarkable stability
to heat. The simultaneous presence of KIO therefore seems
necessary.
Ciernecat chliwacterIstics In our work in respect of the present
invention we applied ourselves particularly to proving the
possible existence of the organic hypoiodite I0-R function where
R is the residue of the hypoiodised ERP, but without any
success.
The classical reactions considered as specific for the presence
of hypoiodite: reaction of hyposulphite which is transformed
into sulphate, of arsenite (which is transformed into arsenate)
of urea into nitrogen and of oxygenated water into oxygen proved
to be negative. Likewise, indigo blue was not bleached by the
product of the invention. It appears therefore that the
hypoiodite fixes on the double link to form an iodohydrin
according to the reaction:
I-OH±CH=ICH->-CHI-CHOH.
The presence of potassium iodide and potassium iodate has been
proved by simple acidification with acetic acid. A bright red
coloration of the solution by liberation of iodine is then
discovered. However, it is necessary to acidify with acetic acid
to obtain with silver nitrate a yellowish and very abundant
precipitate of silver iodide; with lead acetate no precipitate
is obtained and acidification leads only to liberation of
iodine.
Test solutions of XII and of potassium iodate alone or
associated with ERP have given abundant precipitates.
However, although with silver nitrate, in an acid medium at
least, the hypoiodised ERP can be demineralised under the
conditions we have indicated, this does not happen with lead
acetate, the negative reactions of which suggest that KI and
KIOR are very strongly bound or complexed with fthe ERP
molecule.
The organic iodine derivatives according to the invention have
numerous advantages, in particular (a) a pH in the region of
neutrality and (b) very good stability.
The new iodine derivatives have anti-carcinogenic properties.
The most common mineral hypoiodite is potassium hypoiodite.
The new iodine derivatives may be introduced into the organism
particularly intravenously, orally or per rectum for several
months without any disturbance of the blood count and the
leutocytic formula carried out in the course of treatment and
without causing sclerosis or any incident.
The new iodine derivatives therefore are not toxic in
therapeutic doses and do not produce any sensitisation.
Nevertheless, the administration of hypoiodised ERP should, 80
as a precaution, be effected gradually under strict supervision.
Polarographic Characteristics of the ERP-Hypoiodite Product The
polarograph has confirmed the existence of two half-wave
potentials corresponding exactly to those of potassium iodide
and potassium iodate such as are found with test solutions in an
indifferent electrolyte (lithium chloride, and in equivalent
quantities.
Toxicological tests It has not yet been possible to find the
lethal dose for 50%,/ of animals treated (DL 50); several rats
received 5 cm' of 10%o 95 aqueous solutions of hypoiodised ERP
three times a week for four weeks. None of the animals of the 6
treated died or showed the least sign of poisoning. In a healthy
person or one affected by cancerous tumors, 100 no toxicity is
observed, the blood formula remains good as also the level of
urea in the blood. On the other hand, in certain cases of
voluminous tumors of patients, who are already very tired, a
considerable decrease in the red corpuscles is sometimes
observed at the same time as fast melting away of the tumors,
with or without an increase in the level of urea in the blood.
This is indirect intoxication from rapid cell destruction
(lysis) of tumors of people who are already debilitated and
undermined by illness. The administration of hypoiodised ERP to
these patients must be given progressively and under strict
supervision. 115 Therapeutic tests In the case of a rat grafted
with the tumor T8 of Guerin, a clear stoppage of the growth of
the tumor is observed. At the moment it is a matter of simple
inhibition of 120 the evolution of the tumor of the treated rats
compared with that of untreated controls.
Tests are repeated with higher concentrations of hypoiodised
ERP.
With man, using the existing hypoiodised 125 ERP prepared
according to the instructions -1,077,683 1,077,683 indicated,
and according to an example of non-restrictive formula,
Hypoiodised ERP 15 cm' (10% aqueous solution) Nipagine 1/10 000
Ethylene glycol 1 cm' Urethane 3 g Distilled water to 100 cm3
there is obtained considerable cell destruction of tumors with a
cure which it is hoped is complete. The following notes
constitute an example:
Mmme C... of Paut. Ample removal with auxiliary cleansing of the
left breast. Radiotherapy, then shortly after, right pulmonary
metastasis treated by Endoxan. Before the end of this treatment,
left sub-clavicular metastasis. Treatment by hypoiodised ERP, cc
daily intravenously at first, then per rectum, progressive
resorption in approximately 3 months of the pulmonary and
subclavicular metastasis. General condition excellent. Apparent
cure, but the treatment still continuing on a smaller scale.
It will be appreciated that the present invention is not limited
to the above described examples, as other detailed methods and
other detailed forms may be adopted without departing from the
scope of the invention as defined by the claims.
FR1442286
Procédé de stabilisation du triéthylène mélamine et
produits conformes à ceux obtenus par le présent procédé ou
procédé similaire
FR1450394
Procédé de préparation de nouveaux dérivés iodés
notamment de l'éther-oxyde du polyéthylène glycol et de
l'huile de ricin et produits conformes à ceux obtenus par le
présent procédé ou procédé similaire
FR1246706
Substances peroxydantes et leur procédé de préparation
FR3199
Solutés stables et atoxiques de peroxydes, notamment
pour le traitement du cancer.
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