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February 2020
& The Ads They be a-Clique'n' :
Sci-Tech News & Olds, &c...
February 2020
& The Ads They be a-Clique'n' :
Covid19 Updates:https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6
https://flutrackers.com/forum/2019-nCoV Global Cases by Johns Hopkins CSSE
2019-nCov (new coronavirus)https://www.youtube.com/watch?v=9W4zyQ_dqxI
nCV Updates // Dr. John Campbell
https://www.youtube.com/watch?v=Zp3jH6iYrnw&fbclid=IwAR2LwaeCPapdS4daDaprKzfFENtwlh7ZC0CJgZG-o9y1smHj2RtK1OULe-k
Wuhan resident horrific wailing and screaming at night wanting to escape #Coronavirus China Outbreak
https://www.youtube.com/watch?v=qzq4kH6Bruk
Clif High -- critical thinking - Feb 26/2020 - SARS2 - Bio-warfare manual - DECONTAMINATION
https://apps.dtic.mil/dtic/tr/fulltext/u2/a523781.pdf
ARMY, MARINE CORPS, NAVY, AIR FORCE CBRN DECONTAMINATION MULTISERVICE TACTICS, TECHNIQUES, AND PROCEDURES FOR CHEMICAL, BIOLOGICAL, RADIOLOGICAL, AND NUCLEAR DECONTAMINATION
https://www.thelancet.com/pb-assets/Lancet/pdfs/S2213260020300795.pdf
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study
Xiaobo Yang, et al.
https://figueramarathonman.boards.net/
Clemente Figuera Free Energy Generator Forum
https://figueramarathonman.boards.net/thread/22/1932-coutier-device
http://freenrg.info/Patents/FR739458_COUTIER/
Andre L.V. Coutier's Free Energy Generator (1932 )
https://www.ucdavis.edu/news/anti-solar-cells-photovoltaic-cell-works-night
January 29, 2020
Anti-Solar Cells: A Photovoltaic Cell That Works at Night
By Andy Fell
What if solar cells worked at night? That’s no joke, according to Jeremy Munday, professor in the Department of Electrical and Computer Engineering at UC Davis. In fact, a specially designed photovoltaic cell could generate up to 50 watts of power per square meter under ideal conditions at night, about a quarter of what a conventional solar panel can generate in daytime, according to a concept paper by Munday and graduate student Tristan Deppe. The article was published in, and featured on the cover of, the January 2020 issue of ACS Photonics.
Munday, who recently joined UC Davis from the University of Maryland, is developing prototypes of these nighttime solar cells that can generate small amounts of power. The researchers hope to improve the power output and efficiency of the devices.
Munday said that the process is similar to the way a normal solar cell works, but in reverse. An object that is hot compared to its surroundings will radiate heat as infrared light. A conventional solar cell is cool compared to the sun, so it absorbs light.
Space is really, really cold, so if you have a warm object and point it at the sky, it will radiate heat toward it. People have been using this phenomenon for nighttime cooling for hundreds of years. In the last five years, Munday said, there has been a lot of interest in devices that can do this during the daytime (by filtering out sunlight or pointing away from the sun).
Generating power by radiating heat
There’s another kind of device called a thermoradiative cell that generates power by radiating heat to its surroundings. Researchers have explored using them to capture waste heat from engines.
“We were thinking, what if we took one of these devices and put it in a warm area and pointed it at the sky,” Munday said.
This thermoradiative cell pointed at the night sky would emit infrared light because it is warmer than outer space.
“A regular solar cell generates power by absorbing sunlight, which causes a voltage to appear across the device and for current to flow. In these new devices, light is instead emitted and the current and voltage go in the opposite direction, but you still generate power,” Munday said. “You have to use different materials, but the physics is the same.”
The device would work during the day as well, if you took steps to either block direct sunlight or pointed it away from the sun. Because this new type of solar cell could potentially operate around the clock, it is an intriguing option to balance the power grid over the day-night cycle.
https://pubs.acs.org/doi/pdf/10.1021/acsphotonics.9b00679
ACS Photonics 2020, 7, 1, 1-9, November 20, 2019
https://doi.org/10.1021/acsphotonics.9b00679
Nighttime Photovoltaic Cells: Electrical Power Generation by Optically Coupling with Deep Space
Tristan DeppeJeremy N. Munday
Abstract
Photovoltaics possess significant potential due to the abundance of solar power incident on earth; however, they can only generate electricity during daylight hours. In order to produce electrical power after the sun has set, we consider an alternative photovoltaic concept that uses the earth as a heat source and the night sky as a heat sink, resulting in a “nighttime photovoltaic cell” that employs thermoradiative photovoltaics and concepts from the advancing field of radiative cooling. In this Perspective, we discuss the principles of thermoradiative photovoltaics, the theoretical limits of applying this concept to coupling with deep space, the potential of advanced radiative cooling techniques to enhance their performance, and a discussion of the practical limits, scalability, and integrability of this nighttime photovoltaic concept.
http://orthomolecular.org/resources/omns/v16n11.shtml
Orthomolecular Medicine News Service, Feb 16, 2020
Early Large Dose Intravenous Vitamin C is the Treatment of Choice for 2019-nCov Pneumonia
Richard Z Cheng, et al.
The 2019-nCov (coronavirus) epidemic originated in Wuhan, China and is now spreading to many other continents and countries, causing a public fear. Worst of all, there is no vaccine or specific antiviral drugs for 2019-nCov available. This adds to the public fear and gloomy outlook. A quick, rapidly deployable and accessible, effective and also safe treatment is urgently needed to not only save those patients, to curtail the spread of the epidemic, but also very important in the psychological assurance to people worldwide, and to the Chinese in particular. Acute organ failure, especially pulmonary failure (acute respiratory distress syndrome, ARDS) is the key mechanism for 2019-nCov's fatality. Significantly increased oxidative stress due to the rapid release of free radicals and cytokines etc. is the hallmark of ARDS which leads to cellular injury, organ failure and death. Early use of large dose antioxidants, especially vitamin C (VC), therefore, plays a key role in the management of these patients. We call upon all those in the leadership, and those providing direct assistance patients, to bravely and rapidly apply large dose intravenous vitamin C (IVC) to help those patients and to stop this epidemic. ...
https://www.brighteon.com/b4e196ff-d85f-45c4-b4e0-8bc1bea6dc09
https://www.newstarget.com/2020-02-19-covid-19-coronavirus-found-to-contain-gain-of-function-for-efficient-spreading-human-population.html
02/19/2020
CONFIRMED: CoVid-19 coronavirus found to contain unique “gain-of-function” property “for efficient spreading in the human population” … exact quote from science paper just published in Antiviral Research
by Mike Adams
https://www.sciencedirect.com/science/article/abs/pii/S0166354220300528
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same cladeAbstract
B.Coutard, et al.
In 2019, a new coronavirus (2019-nCoV) infecting Humans has emerged in Wuhan, China. Its genome has been sequenced and the genomic information promptly released. Despite a high similarity with the genome sequence of SARS-CoV and SARS-like CoVs, we identified a peculiar furin-like cleavage site in the Spike protein of the 2019-nCoV, lacking in the other SARS-like CoVs. In this article, we discuss the possible functional consequences of this cleavage site in the viral cycle, pathogenicity and its potential implication in the development of antivirals...
https://rense.com/general96/hiv-laced-covid-19-targets-human-testicles.php
HIV-Laced COVID-19 Targets Human Testicles
Its TB Strand Blocks The Immune System
By Yoichi Shimatsu
http://binaryresearchinstitute.com/bri/introduction/
Binary Companion Theory
Researchers at BRI have noticed a number of problems related to the current theory of precession. While VLBI, laser ranging and other related technologies do a good job at determining the earth’s orientation, the sun’s movement through space has not been coordinated with these findings resulting in unintentional bias of precession inputs. In examining the phenomenon of the precession of the equinox (which was the original impetus for the development of lunisolar precession theory) we have found that a moving solar system model is a simpler way to reproduce the same observable without any of the problems associated with current precession theory. Indeed, elliptical orbit equations have been found to be a better predictor of precession rates than Newcomb’s formula, showing far greater accuracy over the last hundred years. Moreover, a moving solar system model appears to solve a number of solar system formation theory problems including the sun’s lack of angular momentum. For these reasons, BRI has concluded our sun is most likely part of a long cycle binary system.
A binary system is two stars gravitationally bound orbiting a common center of mass. The stars can be of the same or differing sizes and orbits can be as short as a few days or as long as thousands of years. The short ones are easy to detect, the long ones difficult, some probably impossible to detect because of the very long observation period required.
While there is no obvious visible companion star to our Sun, there could be a dark binary, such as a brown dwarf or possibly a relatively small black hole, either of which might be very difficult to detect, without accurate and lengthy analysis.
There is also the possibility that our sun might be in a binary or complex gravitational relationship with one of several nearby “visible” stars. This scenario may require thinking beyond standard Newtonian dynamics to embrace MOND or MOG or some similar theory (that suggests that the constant of G might be stronger between stellar objects than between planetary objects within the solar system). There could be many types of unknown and unidentified masses that might cause our solar system to curve through space, including the local stellar cluster and even the galactic center to some small degree, each producing some small effect within the total precession observable. Consequently, at this point our work is primarily focused on understanding the precession observable and its nuances as the likely signature of our solar system’s angular velocity around some common center of mass. We believe that this approach of analyzing the precession observable (the sun’s motion relative to the fixed stars as seen from earth) will provide valuable and helpful data regarding the sun’s most likely stellar companion (if one exists).
In summary, beyond direct detection – one way to determine if we are in a binary or multiple star system is to see if the Sun is curving through space. To us on Earth that means we should experience a gradual “changing orientation to inertial space.” Such a phenomenon is observed as the precession of the equinox...
https://www.paulcraigroberts.org/2020/02/18/will-censorship-prevail-over-the-first-amendment/
Will Censorship Prevail over the First Amendment?
Paul Craig Roberts
https://www.youtube.com/watch?v=BFfuX9nUm-g
Can warm water power the Tesla Turbine??!! COLD STEAM
https://www.youtube.com/watch?v=JvRCB_HhseY&t=1s
Tesla Turbine Running On NEGATIVE Pressure, COLD STEAM!!!
https://www.youtube.com/watch?v=e-E5PPVhLng
Tesla Turbine running on cold steam!
https://www.youtube.com/watch?v=GOyD69-ghd0
The END GAME: Why the WEST is in DECLINE
Felix Rex
Ozone Therapy : http://www.rexresearch.com/o/oindx.htm
https://www.newstarget.com/2020-02-18-south-korea-successfully-treating-coronairus-oxygen-therapy.html
02/18/2020
South Korea says it’s successfully treating coronavirus patient with natural oxygen therapy
By Ethan Huff
In a breakthrough for eradicating the Wuhan coronavirus (CoVid-19), South Korean officials have successfully treated a patient using all-natural oxygen therapy.
Unlike our own Centers for Disease Control and Prevention (CDC), which only advocates for pharmaceuticals and vaccines, Korea’s CDC effectively cured, dare we use that word, a patient by delivering oxygen through a face mask, according to the local news service Newsis.
Jeong Eun-kyeong, director of Korea’s CDC, announced that only one of South Korea’s 21 remaining Wuhan coronavirus (CoVid-19) patients is still in critical condition, while the rest have been released.
As for the oxygen therapy, Jeong explained that it effectively saturates a patient’s body with oxygen by delivering high doses of it. And as we’ve reported in the past, diseases of all kinds hate oxygen and simply can’t survive in its presence.
With this successful treatment, South Korea is confident that there are no additional “critically ill” patients within its border, despite earlier concerns that the virus might ravage high-risk patients...
Clif High re: Covid19 in ALTA Reports --
https://www.youtube.com/watch?time_continue=13&v=ersl7dx-WjI&feature=emb_logo
critical thinking - 2/15/2020 - #covid19 = Sun disease
ALTA Word Cloud Excerpts -- "sun disease"
July 2014
[officialdom agents] [need][population control effort][sun disease][high intensity (solar) regions (such as both sides of the terrestrial equator)][affected] by [extreme energies from sun] [mental processes are disrupted] [humans] [animals] [episodes] [mainstream media] [animal die offs]['muckers' (humans running amok with bad behavior)] next [4/four years] [excessive solar discharge] in 2018 [reeling] [disoriented][disease] [oil/energy problems] [suddenly unstable electricity supplies]
March 2017
'sun disease''odd behavior''seen''sun''disturbances''space satellites'[not]'interdicted by NASA''motivating officialdom''babbling''many collective mouths''conscripted academia''toady media''supporting the narratives''under attack''manifestations in nature''sun disease''twist NASA''loops''bad logic''reconcile''solar behavior''carefully constructed, media enforced, fantasy'
May 2017
'sun disease''sun''humans''afflicted''mental disease''sun disease''standing, drooling''dumbstruck''jittery-ness''uptick in anxiety''frantic''frenetic''humans
on the edge''humans driven mad''solar disease''sun disease effects on humanity''activities''sun disease''feelings and emotions''megalomania''impacts''sun
disease''personally exhilarating''distraction''onrush to war'
https://rense.com/general96/three-great-remote-viewers-blind-targeted-with-the-wuhan-coronavirus.php
Three Great Remote Viewers Blind Targeted With The Wuhan Coronavirus
https://www.zerohedge.com/markets/idiocracy-explained-new-study-finds-western-diet-impairs-brain-function
Idiocracy Explained - New Study Finds Western Diet Impairs Brain Function
https://royalsocietypublishing.org/doi/10.1098/rsos.191338
https://doi.org/10.1098/rsos.191338
Hippocampal-dependent appetitive control is impaired by experimental exposure to a Western-style dietAbstract
Richard J. Stevenson, et al.
Animals fed a Western-style diet (WS-diet) demonstrate rapid impairments in hippocampal function and poorer appetitive control. We examined if this also occurs in humans. One-hundred and ten healthy lean adults were randomized to either a one-week WS-diet intervention or a habitual-diet control group. Measures of hippocampal-dependent learning and memory (HDLM) and of appetitive control were obtained pre- and post-intervention. HDLM was retested at three-week follow-up. Relative to controls, HDLM performance declined in the WS-diet group (d = 0.43), but was not different at follow-up. Appetitive control also declined in the WS-diet group (d = 0.47) and this was strongly correlated with HDLM decline (d = 1.01). These findings demonstrate that a WS-diet can rapidly impair appetitive control in humans—an effect that could promote overeating in consumers of a WS-diet. The study also suggests a functional role for the hippocampus in appetitive control and provides new evidence for the adverse neurocognitive effects of a WS-diet.
Introduction
In animals, an extensive literature suggests that even brief exposure to a Western-style diet (WS-diet), rich in saturated fat and added sugar, results in selective impairment on tests of hippocampal-dependent learning and memory (HDLM, e.g. [1–6]). Emerging evidence in humans suggests a similar conclusion...
https://notrickszone.com/
20. February 2020
New Experimental Evidence: The Atmosphere Cools As More CO2 Is Added…High CO2 ‘May Enhance Net Heat Loss’
By Kenneth Richard
https://cosmosmagazine.com/technology/generating-electricity-out-of-thin-air
Generating electricity 'out of thin air'
Researchers unveil a new device powered by a microbe.
By Nick Carne
Scientists in the US have developed a device they say uses a natural protein to create electricity from moisture in the air.
Writing in the journal Nature, electrical engineer Jun Yao and microbiologist Derek Lovley, from the University of Massachusetts Amherst, introduce the Air-gen (or air-powered generator), which Lovley describes as “the most amazing and exciting application of protein nanowires yet”.
Air-Gen has electrically conductive protein nanowires produced by the microbe Geobacter, which Lovley discovered in the Potomac River three decades ago and has been working with ever since, in particular investigating its potential for “green electronics”.
The Air-gen connects electrodes to the protein nanowires in such a way that electrical current is generated from the water vapour naturally present in the atmosphere.
It requires only a thin film of protein nanowires less than 10 microns thick. The bottom of the film rests on an electrode, while a smaller electrode that covers only part of the nanowire film sits on top...
https://www.zerohedge.com/health/indias-leaders-claim-drinking-cow-urine-will-cure-covid-19
The The Cow Dung Cure for Coronavirus.
Swami Chakrapani Maharaj, president of the Hindu Mahasabha—a century-old organization that advocates Hindutva (or “Hinduness”)—declared that “consuming cow urine and cow dung will stop the effect of infectious coronavirus.”
The swami added that a “person who chants ‘om namah shivay’ and applies cow dung” on his body “will be saved.” The Sanskrit chant is a salutation to Shiva, a Hindu deity..
Related : Urine Therapy
https://www.youtube.com/watch?v=HAKrSNDQuOU
Pandemic Preparedness KitPDF: http://bit.ly/2SwS0b1
https://www.nutreance.com
RediMind[ Acetylcholine ] is the Reason Why Your Memory Is Losing Its Edge
...A team of researchers in a GMP-certified laboratory in New York has identified 5 compounds that can naturally restore optimal levels of acetylcholine. They are Alpha GPC, Huperzine A, Bacopa Monnieri, Lion's Mane Mushroom, and Ginkgo Biloba...
https://www.lowtechmagazine.com/
LOW-TECH MAGAZINE
Doubts on progress and technology
https://www.youtube.com/watch?v=4GRyxuRIPPo
DIY 50,000 Volt Arc Lighter-Powered Tesla Coil (ft. Integza)
https://www.psychologytoday.com/us/blog/your-brain-food/202002/something-amazing-was-discovered-hiding-inside-marijuana
...Recently, two new exciting molecules have been discovered in a marijuana plant. They are variations on the familiar CBD and THC molecules; they have been named cannabidiphorol (CBDP) and Δ9-tetrahydrocannabiphorol (THCP). THCP appears to be thirty times more effective than THC at stimulating the brain’s type one cannabinoid receptor, CB1. This receptor is responsible for producing the euphoria, or the high, associated with marijuana. This means that THCP is thirty times more potent than THC. Therefore, although the level of THCP in the marijuana is quite low, its ability to stimulate CB1 receptors and produce euphoria is quite powerful.
THCP was discovered in one particular variety of marijuana, the Italian FM2 variety. The authors of the study suggested that it is reasonable to predict that other cannabis varieties may contain even higher levels of THCP. Variations in the level of THCP in different marijuana variants might explain why people report such varying levels of psychotropic effects with different plants. The authors of this study expressed excitement that their discovery of such an extremely potent THC-like cannabinoid may shed light on several pharmacological effects not ascribable solely to THC. This makes sense given that the overall experience of marijuana is due to the aggregate effects of all of the molecules in the plant....
FIC Reports (Nature) 9:20335 (2019)
A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-tetrahydrocannabiphorol.
Citti C et al
https://worldwide.espacenet.com/patent/search/family/026142242/publication/EP0837622A1?q=ta%20all%20%22cold%20plasma%20generator%22&queryLang=en
Some Cold Plasma Generator Patents :
WO2017060907A1 // COLD PLASMA OZONE GENERATOR
CN105999566A // Cold plasma disease treatment system and application method thereof
CN201572352U // Cold plasma generator
CN100484361C // Atmospheric discharging cold plasma generator...
EP2445320A1 // Energy harvesting cold atmospheric plasma generator
TWM579530U // Handheld cold plasma generator
RU2613213C1 // COLD PLASMA GENERATOR
CN1327142A // Plasma electric refrigerator
CN1812687A // Atmospheric radio-frequency discharging high-speed cold plasma array generator
WO2017162505A1 // A COLD PLASMA DEVICE FOR TREATING SKIN
CN107297115A // System and method for treating exhaust gas based on cold plasma fusion technique
EP0837622A1 // Plasma generator
RU2227962C2 // GAS-DISCHARGED PLASMA ARC GENERATOR WITH HOLLOW COLD CATHODE
CN108419353A // Cold plasma generator capable of adsorbing ozone
CN105722294A // Atmospheric pressure discharge cold plasma generator
CN106312205A // Method for electrosparking in atmospheric pressure cold plasma jet
CN208462122U // Cold plasma fluidic system based on piezoceramics transformer
CN208402192U // Cold plasma generator of adsorbable ozone
CN205071427U // Simple and easy atmospheric pressure cold plasma generator
US6958063B1 // Plasma generator for radio frequency surgery
CN207653229U // Cold plasma plant mutagenesis device
CN209497663U // Cold plasma generator for mutation breeding
US9067788B1 // Apparatus for highly efficient cold-plasma ozone production
RO132839A0 // EQUIPMENT FOR TREATING SEEDS WITH COLD PLASMA
KR20120028413A // STERILIZING APPARATUS USING HYDROGEN PEROXIDE, OZONE AND COLD PLASMA AND METHOD THEREFOR
&c...
https://www.rt.com/uk/480882-woman-trans-misgendering-verdict/
UK woman convicted for misgendering & calling trans woman ‘pig in a wig’ on Twitter
A British woman has been found guilty of harassing a transgender woman online and hit with a £1,000 fine and two-year conditional discharge. The abuse consisted of offensive tweeting, deliberate misgendering and name-calling.
In a verdict announced by St Albans Magistrates’ Court on Thursday, 39-year-old Katherine Scottow was convicted of using a public communications network – Twitter – to continuously cause “needless anxiety,” annoyance and inconvenience to Stephanie Hayden, 48.
The harassment continued from September 2018 to May 2019, and included deliberate “misgendering” of Hayden and repeatedly referring to the transgender woman by male pronouns, as well as name-calling, including Scottow referring to Hayden as a “pig in a wig.”...
[ That goes double for the putative judge ]
https://www.hempfarmingacademy.com
https://www.youtube.com/watch?v=1YhQ4GuReoY&feature=youtu.be
How to farm #Hemp in 2020 - Learn to become a profitable Hemp Farmer
http://strangecarsandthings.blogspot.com/2007/12/its-21st-century-where-hells-my-flying.html
It's the 21st Century. Where the Hell's My Flying Car?
Coronavirus References:
https://b-ok.cc/book/2144279/65e309
Molecular Biology of the SARS-Coronavirus // Ilona Glowacka, et al.
https://b-ok.cc/book/2800356/13397b
Coronaviruses // John Ziebuhr (Eds.)(2016)
https://b-ok.cc/book/657751/1b2fec
SARS- and Other Coronaviruses: Laboratory Protocols // Leen Vijgen PhD, et al. (2008)
https://b-ok.cc/book/810220/865ea2?dsource=recommend
Sars: Reception and Interpretation in Three Chinese Cities // Deborah Davis, Helen F. Siu (2006)
https://b-ok.cc/book/898988/a49ac3?dsource=recommend
SARS, Governance and the Globalization of Disease // David P. Fidler
https://b-ok.cc/book/3405996/baefce?dsource=recommend
SARS, MERS and other Viral Lung Infections // David S. Hui, et al.
https://b-ok.cc/book/2249863/f8e98f?dsource=recommend
Coronaviruses and their Diseases // D. Cavanagh, D
https://b-ok.cc/book/2140166/8f98e6
Coronaviruses: Molecular Biology and Virus-Host Interactions // Brian C. Horsburgh, et al.
https://b-ok.cc/book/2491104/d7944e
Coronaviruses: Methods and Protocols // Helena Jane Maier, et al. (2015)
https://b-ok.cc/book/986094/3789e0
Coronavirus Replication and Reverse Genetics (Current Topics in Microbiology and Immunology) // Luis Enjuanes (Editor)(2004)
https://b-ok.cc/book/2144279/65e309?dsource=recommend
Molecular Biology of the SARS-Coronavirus // Ilona Glowacka, et al. (2010)
https://b-ok.cc/book/2206593/fe8a6c
Coronaviruses with Special Emphasis on First Insights Concerning SARS // Dave Cavanagh (auth.), et al. (2005)
https://b-ok.cc/book/2837477/253398?dsource=recommend
Animal Coronaviruses // Leyi Wang (eds.)
https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1
https://doi.org/10.1101/2020.01.30.927871
Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag
Prashant Pradhan, et al.
https://www.sciencedaily.com/releases/2014/02/140227142250.htm
February 27, 2014
Deadly immune 'storm' caused by emergent flu infections
https://www.pnas.org/content/111/10/3799
Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection
John R. Teijaro, et al.
https://themindunleashed.com/2020/02/new-handheld-device-prints-skin-directly-onto-wounds.html
New Handheld Device “Prints” Skin Directly Onto Wounds
Scientists have created a handheld printer that patches up damaged skin.
by Aaron Kesel
Every day science is making medical discoveries that can change our lives. And now scientists have created a handheld skin printer that patches up damaged skin due to injuries such as extreme burns.
Spanish scientists from the Universidad Carlos III de Madrid (UC3M), Center for Energy, Environmental and Technological Research (CIEMAT) created a large bioprinter that prints human skin in 2017.
Then In 2018, Canadian scientists advanced the research and revealed a handheld device that “prints” sheets of artificial skin directly onto the wounds of burn victims.
“The analogy is a duct tape dispenser,” researcher Axel Günther told Smithsonian Magazine at the time, “where instead of a roll of tape you have a microdevice that squishes out a piece of tissue tape.”
The Canadian scientists recently published the hopeful results of their latest trial of the handheld device in the journal Biofabrication. Doctors currently have several possibilities for treating severe burns including collagen scaffolds, in vitro skin substitutes, and skin grafts.
The most commonly used method is skin grafts which involves removing damaged tissue and replacing it with healthy skin from another part of the body. But grafts aren’t always a viable option.
“[I]n cases where a patient has extensive full-thickness burns—which destroy both the upper and lower layers of the skin—there is not always sufficient healthy skin left to use,” Günther explained in a press release.
Alternative burn treatments such as collagen scaffolds and in vitro skin substitutes, each have their own downsides, Günther also said.
These are the reasons given for why the team created a device that eliminates the need for skin grafts altogether by depositing strips of a special bio-ink directly onto a wound. The bio-ink contains healing proteins and mesenchymal stromal cells which aid the body’s immune system and stimulates new cell growth, according to the researchers.
For the trial, scientists tested the skin printing device on full-thickness burns on pigs and they were very impressed with the results.
“We found the device successfully deposited the ‘skin sheets’ onto the wounds uniformly, safely and reliably, and the sheets stayed in place with only very minimal movement,” Marc Jeschke said in the press release.
“Most significantly, our results showed that the [mesenchymal stromal cell]-treated wounds healed extremely well,” he continued, “with a reduction in inflammation, scarring, and contraction compared with both the untreated wounds and those treated with a collagen scaffold.”
In 2016, researchers at Harvard University made the first 3-D-printed heart-on-a-chip with integrated sensing. And in 2019 that research was advanced when Israeli scientists created the first 3D-printed heart using human tissue and vessels. They engineered the heart from the tissue of patients and created a bio-ink, Telegraph reported.
This new skin can also be used in the research and testing of cosmetics, chemicals, and pharmaceutical products that go on and into the human body.
Skin “can be transplanted into patients or used in business settings to test chemical products, cosmetics or pharmaceutical products in quantities and with timetables and prices that are compatible with these uses,” Professor José Luis Jorcano head of the Mixed Unit CIEMAT/UC3M in Biomedical Engineering said previously.
On the other hand, some may argue that this is a giant leap towards “transhumanism
https://www.youtube.com/watch?v=NNOoHC_v5Tw&feature=emb_logo
Jan 22, 2017
Científicos españoles crean una bioimpresora 3D de piel humana
Scientists from the Universidad Carlos III de Madrid (UC3M), CIEMAT (Center for Energy, Environmental and Technological Research), Hospital General Universitario Gregorio Marañón, in collaboration with the firm BioDan Group, have presented a prototype for a 3D bioprinter that can create totally functional human skin. This skin is adequate for transplanting to patients or for use in research or the testing of cosmetic, chemical, and pharmaceutical products.
https://www.smithsonianmag.com/innovation/handheld-device-could-print-new-skin-burn-victims-180969165/
May 30, 2018
This Handheld Device Could Print New Skin Onto Burn Victimshttps://pubs.rsc.org/en/content/articlelanding/2018/lc/c7lc01236e#!divAbstract
The machine prints sheets of a skin substitute directly onto burn wounds, potentially making skin grafting faster, cheaper and easier
By Emily Matchar
Handheld skin printer: in situ formation of planar biomaterials and tissues
Navid Hakimi, et al.
https://ioppublishing.org/news/new-handheld-bioprinter-holds-promise-for-treating-serious-burns/
Handheld instrument for wound-conformal delivery of skin precursor sheets improves healing in full-thickness burns
Richard Y Cheng, et al.
US2019274747A1
System and Method for Treating Cancer Through DNA Damage With Cold Atmospheric Plasma With Self-organized Patterns
The present invention creates plasma with different self-organization patterns (SOPs) to activate saline solution. The plasma activated saline solutions have anti-tumor effects on human cancer cells.
https://vimeo.com/348470103
mitocopper.com/products/apex-direct-oxygen-infusion-protocol
888-809-8385
https://cdn.shopify.com/s/files/1/0012/8096/6722/files/REPORT-_APeX_Water_NSearch_1.pdf?13337453794712189083
REPORT:THE SCIENCE AND EFFICACY OFAPeX OXYGENATEDWATER
submitted by Jane G. Goldberg, Ph.D
https://abc14news.com/2020/02/05/electricity-generator-can-power-100-small-led-light-bulbs-from-a-single-raindrop/
Electricity Generator Can Power 100 Small LED Light Bulbs From A Single Raindrop
A research team led by scientists from the City University of Hong Kong (CityU) has recently developed a droplet-based electricity generator (DEG) with a field-effect transistor (FET)-like structure that allows for high energy conversion efficiency and instantaneous power density thousands of times that of its counterparts without FET technology. This would help to advance scientific research of water energy generation and tackle the energy crisis.
The research was led together by Professor Wang Zuankai from CityU's Department of Mechanical Engineering, Professor Zeng Xiao Cheng from University of Nebraska-Lincoln, and Professor Wang Zhong Lin, founding director and chief scientist from Beijing Institute of Nanoenergy and Nanosystems of Chinese Academy of Sciences. Their findings were published in Nature in a study titled "A droplet-based electricity generator with high instantaneous power density."
Efficiency of electrical energy conversion greatly improved
About 70% of the Earth's surface is covered by water. Yet low-frequency kinetic energy contained in waves, tides, and even raindrops are not efficiently converted into electrical energy due to limitations in current technology. For example, a conventional droplet energy generator based on the triboelectric effect can generate electricity induced by contact electrification and electrostatic induction when a droplet hits a surface. However, the amount of charges generated on the surface is limited by the interfacial effect, and as a result, the energy conversion efficiency is quite low.
In order to improve the conversion efficiency, the research team has spent two years developing the DEG. Its instantaneous power density can reach up to 50.1 W/m2, thousands times higher than other similar devices without the use of FET-like design. And the energy conversion efficiency is markedly higher.
Professor Wang from CityU pointed out that there are two crucial factors for the invention. First, the team found that the continuous droplets impinging on PTFE, an electret material with a quasi-permanent electric charge, provides a new route for the accumulation and storage of high-density surface charges. They found that when water droplets continuously hit the surface of PTFE, the surface charges generated will accumulate and gradually reach a saturation. This new discovery helped to overcome the bottleneck of low charge density encountered in previous work.
Unique field-effect transistor-like structure
Another key feature of their design is a unique set of structures similar to a FET, the basic building block of modern electronic devices. The device consists of an aluminum electrode and an indium tin oxide (ITO) electrode with a film of PTFE deposited on it. The PTFE/ITO electrode is responsible for the charge generation, storage and induction. When a falling water droplet hits and spreads on the PTFE/ITO surface, it naturally "bridges" the aluminum electrode and the PTFE/ITO electrode, translating the original system into a closed-loop electric circuit.
With this special design, a high density of surface charges can be accumulated on the PTFE through continuous droplet impinging. Meanwhile, when the spreading water connects the two electrodes, all the stored charges on the PTFE can be fully released for the generation of electric current. As a result, both the instantaneous power density and energy conversion efficiency are much higher.
"Our research shows that a drop of 100 microliters of water released from a height of 15 cm can generate a voltage of over 140V. And the power generated can light up 100 small LED light bulbs," said Professor Wang.
He added that the increase in instantaneous power density does not result from additional energy, but from the conversion of kinetic energy of water itself. "The kinetic energy entailed in falling water is due to gravity and can be regarded as free and renewable. It should be better utilized."
Their research also shows that the reduction in relative humidity does not affect the efficiency of power generation. Also, both rainwater and seawater can be used to generate electricity.
Facilitates the sustainability of the world
Professor Wang hoped that the outcome of this research would help to harvest water energy to respond to the global problem of renewable energy shortage. "Generating power from raindrops instead of oil and nuclear energy can facilitate the sustainable development of the world," he added.
He believed that in the long run, the new design could be applied and installed on different surfaces, where liquid in contact with solid, to fully utilize the low-frequency kinetic energy in water. This can range from the hull surface of ferry, coastline, to the surface of umbrellas or even inside water bottles.
https://techxplore.com/news/2020-02-droplet-based-electricity-140v-power-bulbs.html
New droplet-based electricity generator: A drop of water generates 140V power, lighting up 100 LED bulbs
by City University of Hong Kong
https://www.nature.com/articles/s41586-020-1985-6
05 February 2020
DOI: 10.1038/s41586-020-1985-6
A droplet-based electricity generator with high instantaneous power densityAbstract
Wanghuai Xu, et al.
Extensive efforts have been made to harvest energy from water in the form of raindrops1,2,3,4,5,6, river and ocean waves7,8, tides9 and others10,11,12,13,14,15,16,17. However, achieving a high density of electrical power generation is challenging. Traditional hydraulic power generation mainly uses electromagnetic generators that are heavy, bulky, and become inefficient with low water supply. An alternative, the water-droplet/solid-based triboelectric nanogenerator, has so far generated peak power densities of less than one watt per square metre, owing to the limitations imposed by interfacial effects—as seen in characterizations of the charge generation and transfer that occur at solid–liquid1,2,3,4 or liquid–liquid5,18 interfaces. Here we develop a device to harvest energy from impinging water droplets by using an architecture that comprises a polytetrafluoroethylene film on an indium tin oxide substrate plus an aluminium electrode. We show that spreading of an impinged water droplet on the device bridges the originally disconnected components into a closed-loop electrical system, transforming the conventional interfacial effect into a bulk effect, and so enhancing the instantaneous power density by several orders of magnitude over equivalent devices that are limited by interfacial effects.
https://www.rochester.edu/newscenter/superhydrophobic-metal-wont-sink-406272/
November 6, 2019
Spiders and ants inspire metal that won’t sink
University of Rochester researchers, inspired by diving bell spiders and rafts of fire ants, have created a metallic structure that is so water repellent, it refuses to sink—no matter how often it is forced into water or how much it is damaged or punctured.
Could this lead to an unsinkable ship? A wearable flotation device that will still float after being punctured? Electronic monitoring devices that can survive in long term in the ocean?
All of the above, says Chunlei Guo, professor of optics and physics, whose lab describes the structure in ACS Applied Materials and Interfaces.
The structure uses a groundbreaking technique the lab developed for using femtosecond bursts of lasers to “etch” the surfaces of metals with intricate micro- and nanoscale patterns that trap air and make the surfaces superhydrophobic, or water repellent.
The researchers found, however, that after being immersed in water for long periods of time, the surfaces may start to lose their hydrophobic properties.
Enter the spiders and fire ants, which can survive long periods under or on the surface of water. How? By trapping air in an enclosed area. Argyroneta aquatic spiders, for example, create an underwater dome-shaped web—a so-called diving bell— that they fill with air carried from the surface between their super-hydrophobic legs and abdomens. Similarly, fire ants can form a raft by trapping air among their superhydrophobic bodies.
“That was a very interesting inspiration,” Guo says. As the researchers note in the paper: “The key insight is that multifaceted superhydrophobic (SH) surfaces can trap a large air volume, which points towards the possibility of using SH surfaces to create buoyant devices.”
Guo’s lab created a structure in which the treated surfaces on two parallel aluminum plates face inward, not outward, so they are enclosed and free from external wear and abrasion. The surfaces are separated by just the right distance to trap and hold enough air to keep the structure floating—in essence creating a waterproof compartment. The superhydrophobic surfaces will keep water from entering the compartment even when the structure is forced to submerge in water.
Even after being forced to submerge for two months, the structures immediately bounced back to the surface after the load was released, Guo says. The structures also retained this ability even after being punctured multiple times, because air remains trapped in remaining parts of the compartment or adjoining structures.
Though the team used aluminum for this project, the “etching process “could be used for literally any metals, or other materials,” Guo says.
When the Guo lab first demonstrated the etching technique, it took an hour to pattern a one-inch-by-one-inch area of surface. Now, by using lasers seven times as powerful, and faster scanning, the lab has speeded up the process, making it more feasible for scaling up for commercial applications.
Coauthors include lead author Zhibing Zhan, Mohamed ElKabbash, Jihua Zhang, and Subhash Singh, all PhD candidates or postdoctoral fellows in Guo’s lab, and Jinluo Cheng, associate professor at the Changchun Institute of Optics, Fine Mechanics, and Physics in China.
The project was supported by funding from the Bill & Melinda Gates Foundation, the US Army Research Office, and National Science Foundation.
https://phys.org/news/2019-07-mechanism-droplets-record-high-distance-extra.html
July 22, 2019
New mechanism moving droplets at record-high speed and long distance without extra power
...the researchers have devised a new strategy that achieves the unidirectional and self-propelled liquid droplet transportation on diverse substrates. Their work demonstrates unprecedented performance: The highest transport velocity (1.1m/s) is 10 times higher than ever before reported, and represents the longest unlimited transport distance...
https://www.sciencemag.org/news/2019/12/rivers-could-generate-thousands-nuclear-power-plants-worth-energy-thanks-new-blue
Dec. 4, 2019
Rivers could generate thousands of nuclear power plants worth of energy, thanks to a new ‘blue’ membrane
By Robert F. Service
Green energy advocates may soon be turning blue. A new membrane could unlock the potential of “blue energy,” which uses chemical differences between fresh- and saltwater to generate electricity. If researchers can scale up the postage stamp–size membrane in an affordable fashion, it could provide carbon-free power to millions of people in coastal nations where freshwater rivers meet the sea.
“It’s impressive,” says Hyung Gyu Park, a mechanical engineer at Pohang University of Science and Technology in South Korea who wasn’t involved with the work. “Our field has waited for this success for many years.”
Blue energy’s promise stems from its scale: Rivers dump some 37,000 cubic kilometers of freshwater into the oceans every year. This intersection between fresh- and saltwater creates the potential to generate lots of electricity—2.6 terawatts, according to one recent estimate, roughly the amount that can be generated by 2000 nuclear power plants.
There are several ways to generate power from that mixing. And a couple of blue energy power plants have been built. But their high cost has prevented widespread adoption. All blue energy approaches rely on the fact that salts are composed of ions, or chemicals that harbor a positive or negative charge. In solids, the positive and negative charges attract one another, binding the ions together. (Table salt, for example, is a compound made from positively charged sodium ions bound to negatively charged chloride ions.) In water, these ions detach and can move independently.
By pumping the positive ions—like sodium or potassium—to the other side of a semipermeable membrane, researchers can create two pools of water: one with a positive charge, and one with a negative charge. If they then dunk electrodes in the pools and connect them with a wire, electrons will flow from the negatively charged to the positively charged side, generating electricity.
In 2013, French researchers made just such a membrane. They used a ceramic film of silicon nitride—commonly used in industry for electronics, cutting tools, and other uses—pierced by a single pore lined with a boron nitride nanotube (BNNT), a material being investigated for use in high-strength composites, among other things. Because BNNTs are highly negatively charged, the French team suspected they would prevent negatively charged ions in water from passing through the membrane (because similar electric charges repel one another). Their hunch was right. They found that when a membrane with a single BNNT was placed between fresh- and saltwater, the positive ions zipped from the salty side to the fresh side, but the negatively charged ions were mostly blocked.
The charge imbalance between the two sides was so strong that the researchers estimated a single square meter of the membrane—packed with millions of pores per square centimeter—could generate about 30 megawatt hours per year. That’s enough to power three homes.
But creating even postage stamp–size films has proved impossible, because no one has figured out how to make all of the long, thin BNNTs line up perpendicular to the membrane. Until now.
At the semiannual meeting of the Materials Research Society here yesterday, Semih Cetindag, a Ph.D. student in the lab of mechanical engineer Jerry Wei-Jen Shan at Rutgers University in Piscataway, New Jersey, reported that their team has now cracked the code. The nanotubes were easy. Cetindag says the lab just buys them from a chemical supply company. The scientists then add these to a polymer precursor that’s spread into a 6.5-micrometer-thick film. To orient the randomly aligned tubes, the researchers wanted to use a magnetic field. The problem: BNNTs aren’t magnetic.
So Cetindag painted the negatively charged tubes with a positively charged coating; the molecules that made it up were too large to fit inside the BNNTs and thus left their channels open. Cetindag then added negatively charged magnetic iron oxide particles to the mix, which affixed to the positively charged coatings.
That gave the Rutgers team the lever it was looking for. When the researchers applied a magnetic field, they could maneuver the tubes so that most aligned across the polymer film. They then applied ultraviolet light to cure the polymer, locking everything in place. Finally, the team used a plasma beam to etch away some of the material on the top and bottom surfaces of the membrane, ensuring the tubes were open to either side. The final membrane contained some 10 million BNNTs per cubic centimeter.
When the researchers placed their membrane in a small vessel separating salt- and freshwater, it produced four times more power per area than the previous French team’s BNNT experiment. That power boost, Shan says, is likely because the BNNTs they used are narrower, and thus do a better job of excluding negatively charged chloride ions.
And they suspect they can do even better. “We’re not exploiting the full potential of the membranes,” Cetindag says. That’s because only 2% of the BNNTS were actually open on both sides of the membrane after the plasma treatment. Now, the researchers are trying to increase number of open pores in their films—which could one day give a long-sought boost to advocates of blue energy.
http://absimage.aps.org/image/DFD19/MWS_DFD19-2019-002596.pdf
Abstract Submittedfor the DFD19 Meeting ofThe American Physical Society
Enhanced Electrokinetic Energy Conversion & Ion-SelectiveTransport in Macroscopic Vertically Aligned BNNT Membranes
Semih Cetindag, et al.
WO2019014633A1Abstract
BORON-NITRIDE NANOTUBE MEMBRANES
Disclosed herein are boron-nitride nanoparticle membranes and methods of manufacturing boron-nitride nanoparticle membranes. In an embodiment, a boron-nitride nanoparticle membrane includes a matrix and a plurality of one-dimensional boron-nitride nanoparticles disposed within the matrix, where he plurality of boron-nitride nanoparticles are configured for selective molecular transport through each of the plurality of one-dimensional boron-nitride nanoparticles.
https://www.youtube.com/watch?v=O2jxTZNyFN4&feature=emb_logo
History Mathematically Proven Wrong
https://www.youtube.com/watch?time_continue=6&v=HXD2MQfc6qg&feature=emb_logo
Anatoly Fomenko Hidden History (Part1)
https://www.youtube.com/watch?v=24rQm59fY5Y
Anatoly Fomenko Hidden History (Part2)
https://www.youtube.com/watch?v=wkSRsZNpjTQ
END GAME - The Fall of the West?
https://www.youtube.com/watch?v=-uOwv_Krqk8&feature=emb_logo
Draining Earth's oceans, revealing the two-thirds of Earth's surface we don't get to see
Remake of an animation NASA made back in 2008, but at high resolution and with edited timing (https://svs.gsfc.nasa.gov/3487), the previous version was 1024x512 while this one is 3840x2160 (4K).
https://www.youtube.com/watch?v=PUwmA3Q0_OE
Human Population Through Time
American Museum of Natural History
It took 200,000 years for our human population to reach 1 billion—and only 200 years to reach 7 billion. But growth has begun slowing, as women have fewer babies on average. When will our global population peak? And how can we minimize our impact on Earth’s resources, even as we approach 11 billion?
https://www.youtube.com/watch?v=jk3g9hrvhJc
Coronavirus: New World Begins as Grand Solar Minimum Food Shortages Loom
Adapt 2030
As was forecast that about one year before global food shortages rocked the planet a purposeful implosion of the global economy would occur to stop people from moving to better food secure regions on the planet. Here we sit with a virus that will accomplish a full lock down of the entire globe and crash the global economy. A double layer of lock down so where you are stuck is where you stay. This is what you +can expect moving forward with governmental control, the economy and your lives. Good luck in your preparations.
https://www.brighteon.com/f7eaac7c-b3d2-4ab3-b83d-9deb039782f4
Illuminati Card Game Predicted the Corona Virus Outbreak in Wuhan China!!
https://www.youtube.com/watch?v=elogl7gbFSI
http://www.free-energy-info.com/Aerials.pdf
Aerial technology for high power systems of 100 kilowatts and higher[ Actually, this was invented in the 1930s ]
Patrick Kelly
https://www.dailymail.co.uk/sciencetech/article-7112651/Michelin-unveils-AIRLESS-tyres-available-just-five-years.html
'Puncture-proof' AIRLESS tyres that are cheaper, more durable and better for the environment than traditional versions may be available to buy in just five yearshttps://www.michelin.com/en/press-releases/michelin-gm-take-the-air-out-of-tires-for-passenger-vehicles/
June 4 2019
MICHELIN, GM take the air out of tires for passenger vehicles
Michelin and General Motors presented a new generation of airless wheel technology for passenger vehicles — the MICHELIN Uptis Prototype (or “Unique Punctureproof Tire System”) — at the Movin’On Summit for sustainable mobility.
https://linkinghub.elsevier.com/retrieve/pii/S2451929419302025
Volume 5, ISSUE 7, P1871-1882, July 11, 2019
DOI:https://doi.org/10.1016/j.chempr.2019.04.025
Biomimetic Carbon Tube Aerogel Enables Super-Elasticity and Thermal InsulationHighlights
Hui-Juan Zhan, et al.
Bioinspired fabrication of a macroscopic-scale lightweight carbon tube aerogel.
The CTA materials show super-elasticity with the rebounding speed of 1,434 mm/s.
The microstructure-derived CTA materials show excellent thermal insulation property.
Summary
Inspired by microstructures of polar bear hair, herein, we describe a simple solution-based strategy to fabricate a macroscopic-scale and lightweight carbon tube aerogel with super-elasticity and excellent thermal insulation. The microstructure-derived thermal conductivity and super-elasticity are strongly dependent on the shell thickness of the interconnected tubes, as well as the aperture of the aerogel. Remarkably, the optimized aerogel can maintain structural integrity after more than one million compress-release cycles at 30% strain and 10,000 cycles at 90% strain. Moreover, this biomimetic aerogel offers a fast and accurate dynamic piezoresistive response to broad bandwidth frequency forces. Particularly, the super-elasticity is further confirmed by its fastest rebounding speed of 1,434 mm s −1 among the traditional elastic materials measured by a standard falling steel ball. Furthermore, the optimized minimum thermal conductivity is as low as 23 mW m −1 K −1 which performs better than the thermal conductivity of dry air.
A Thermally Insulating Textile Inspired by Polar Bear HairAbstract
Ying Cui, et al.14 February 2018
Animals living in the extremely cold environment, such as polar bears, have shown amazing capability to keep warm, benefiting from their hollow hairs. Mimicking such a strategy in synthetic fibers would stimulate smart textiles for efficient personal thermal management, which plays an important role in preventing heat loss and improving efficiency in house warming energy consumption. Here, a “freeze‐spinning” technique is used to realize continuous and large‐scale fabrication of fibers with aligned porous structure, mimicking polar bear hairs, which is difficult to achieve by other methods. A textile woven with such biomimetic fibers shows an excellent thermal insulation property as well as good breathability and wearability. In addition to passively insulating heat loss, the textile can also function as a wearable heater, when doped with electroheating materials such as carbon nanotubes, to induce fast thermal response and uniform electroheating while maintaining its soft and porous nature for comfortable wearing.
https://www.nature.com/articles/nature08729/
Nature volume 463, pages640–643(2010), 04 February 2010
Directional water collection on wetted spider silkAbstract
Yongmei Zheng, Hao Bai, Zhongbing Huang, Xuelin Tian, Fu-Qiang Nie, Yong Zhao, Jin Zhai & Lei Jiang
Many biological surfaces in both the plant and animal kingdom possess unusual structural features at the micro- and nanometre-scale that control their interaction with water and hence wettability1,2,3,4,5. An intriguing example is provided by desert beetles, which use micrometre-sized patterns of hydrophobic and hydrophilic regions on their backs to capture water from humid air6. As anyone who has admired spider webs adorned with dew drops will appreciate, spider silk is also capable of efficiently collecting water from air. Here we show that the water-collecting ability of the capture silk of the cribellate spider Uloborus walckenaerius is the result of a unique fibre structure that forms after wetting, with the ‘wet-rebuilt’ fibres characterized by periodic spindle-knots made of random nanofibrils and separated by joints made of aligned nanofibrils. These structural features result in a surface energy gradient between the spindle-knots and the joints and also in a difference in Laplace pressure, with both factors acting together to achieve continuous condensation and directional collection of water drops around spindle-knots. Submillimetre-sized liquid drops have been driven by surface energy gradients7,8,9 or a difference in Laplace pressure10, but until now neither force on its own has been used to overcome the larger hysteresis effects that make the movement of micrometre-sized drops more difficult. By tapping into both driving forces, spider silk achieves this task. Inspired by this finding, we designed artificial fibres that mimic the structural features of silk and exhibit its directional water-collecting ability.
https://science.sciencemag.org/content/256/5063/1539
Science 12 Jun 1992: Vol. 256, Issue 5063, pp. 1539-1541
DOI: 10.1126/science.256.5063.1539
How to Make Water Run UphillAbstract
Manoj K. Chaudhury1, George M. Whitesides2
A surface having a spatial gradient in its surface free energy was capable of causing drops of water placed on it to move uphill. This motion was the result of an imbalance in the forces due to surface tension acting on the liquid-solid contact line on the two opposite sides ("uphill" or "downhill") of the drop. The required gradient in surface free energy was generated on the surface of a polished silicon wafer by exposing it to the diffusing front of a vapor of decyltrichlorosilane, Cl3Si(CH2)9CH3. The resulting surface displayed a gradient of hydrophobicity (with the contact angle of water changing from 97° to 25°) over a distance of 1 centimeter. When the wafer was tilted from the horizontal plane by 15°, with the hydrophobic end lower than the hydrophilic, and a drop of water (1 to 2 microliters) was placed at the hydrophobic end, the drop moved toward the hydrophilic end with an average velocity of ∼1 to 2 millimeters per second. In order for the drop to move, the hysteresis in contact angle on the surface had to be low (≤10°).
M. Keshe says:
https://www.youtube.com/watch?v=08UZ7eeN7k4
OneCup OneLife eradicates Wuhan Coronavirus
Keshe Foundation Spaceship Institute
https://thomasdishaw.com/bookmark-400-links-google-doesnt-want-visit/
http://republicbroadcasting.org/news/bookmark-this-over-400-links-google-doesnt-want-you-to-visit-2/
Over 400 Links Google Doesn’t Want You To Visit
https://thomasdishaw.com/democrats/
400 Gun and Ammo sites Democrats don’t want you to visit
https://thomasdishaw.com/bookmark-this-comprehensive-list-of-170-open-source-intelligence-tools/
Comprehensive List of 170 Open Source Intelligence Tools
https://thomasdishaw.com/privacy/
150 ways to take back your privacy from the evil gatekeepers
https://www.scidev.net/global/energy/news/potato-battery-could-help-meet-rural-energy-needs.html?__cf_chl_jschl_tk__=d14e333b2d0362dbba1b12c4a6fe2c641c82627f-1580592505-0-AW4x2xI6--cQPEN2bQWGccmPYa5VY9smnb_qAN9IprLawX4rqKmnOR0n7NS0f5NaFcJVzJPhkfBESvUuIL8oVbWMr7t72TYAqpjI-qBzdZKx7lyz7BaAupL1vaevCqpunZDp0t0rwgtGYrbMGemmLg0OCNLW379-SfFaEOfyybg9RaPTONQNFKzCtm82GCwlbFAnvJecfkjOZOmOILuqNhwLE6I58AVXF-8opTX4CCqToTO6U7FP2wd1GTsAXXKVW7DWyNjmnOhkt9jpkn0zWaQHpWf2fCn_5Dh6pYB1jCH8G5YEPqBuma9hsn2_CjiLnxmIn9iFfKDmCUX4cKs_Bp44MH-e3Bh9NvQfnOfm4SQs
Potato battery could help meet rural energy needs
The holy grail of renewable energy research may lie in the cooking pot, according to scientists.
The search for a cheap source of electricity for remote, off-grid communities, has led to batteries that work on freshly boiled potatoes.
One slice of potato can generate 20 hours of light, and several slices could provide enough energy to power simple medical equipment and even a low-power computer, said a research team from the Hebrew University of Jerusalem, Israel.
"The technology is ready to go," co-researcher Haim Rabinowitch told SciDev.Net. "It should take an interested body only a short while, and very little investment, to make this available to communities in need."
The team, which described its work in the Journal of Renewable and Sustainable Energy earlier this month (7 June), said its work hinges on a recent discovery that the electrical flow from potatoes — long known to be natural electrolytes — can be enhanced tenfold when their cell membranes are deliberately ruptured by boiling.
To demonstrate, the researchers created a series of batteries out of slices of boiled Desiree potatoes about the size of a standard mobile phone, though they say the type and size of potato slice do not determine its power.
The device had the same basic components as conventional batteries, consisting of two electrodes separated by an electrolyte (the potato). Each battery powered a small light for 20 hours, after which a new slice could be inserted.
Potato batteries are estimated to generate energy at a cost of approximately US$9 per kilowatt hour (kW/h), which compares favourably with the best performing 1.5 volt (AA) alkaline cells — or D cells — which generate energy at US$50/kWh.
Banana and strawberry batteries could also be used, said Rabinowitch, but their softer tissues would weaken the structure of the battery and the sugars could attract insects.
"Potatoes were chosen because of their availability all over including the tropics and sub-tropics," he said. They are the world's fourth most abundant food crop."
Teo Sanchez, energy technology and policy advisor at Practical Action, a charity which promotes technology for development, said: "With half the world's population having no access to modern energy, this research is a valuable contribution to one of the biggest challenges in the world".
But he is concerned about the limited amount of power that individual batteries can generate and the possible implications of diverting a food crop into energy production.
https://www.youtube.com/user/TheEngpjk/videos
Patrick Kelly's YouTube Channel
http://www.free-energy-info.com/
The Practical Guide to Free Energy Devices
https://www.youtube.com/watch?v=kfYiQVzB3Cg
Making a Simple HHO Generator under 5$
M.N. Projects
I wanted to make the simplest pocket HHO generator. The use of screws gives us a large electrode surface due to the thread, in addition it is very cheap. To build such a generator, all you need is a drill and some good intentions. Good luck in your constructions!
https://ieeexplore.ieee.org/abstract/document/8871349
The Plasma Compression Fusion Device—Enabling Nuclear Fusion IgnitionAbstract
Salvatore Cezar Pais
The plasma compression fusion device (PCFD) generates the energy gain by plasma compression-induced nuclear fusion. This concept has the capability of maximizing the product of plasma pressure and energy confinement time to maximize the energy gain, and thus give rise to fusion ignition conditions. The preferred embodiment of this original concept uses a hollow cross-duct configuration of circular cross section in which the concentrated magnetic energy flux from two pairs of opposing curved-headed counter-spinning conical structures (possibly made from an alloy of tungsten with high capacitance) whose outer surfaces are electrically charged compresses a gaseous mixture of fusion fuel into a plasma, heated to extreme temperatures and pressures. The generated high-intensity electromagnetic (EM) radiation heats the plasma and the produced magnetic fields confine it in between the counter-spinning conical structures, named the dynamic fusors (four of them-smoothly curved apex sections opposing each other in pairs). The dynamic fusors can be assemblies of electrified grids and toroidal magnetic coils, arranged within a conical structure whose outer surface is electrically charged. The cross-duct inner surface surrounding the plasma core region is also electrically charged and vibrated in an accelerated mode to minimize the flux of plasma particles (including neutrals) from impacting the PCFD surfaces and initiating a plasma quench. The fusion fuel (preferably deuterium gas) is introduced into the plasma core through the counterspinning conical structures, namely, injected through orifices in the dynamic fusor heads. There is envisioned another even more compact version of this concept, which uses accelerated vibration in a linear-duct configuration (using two counterspinning dynamic fusors only) and would best be suited for fusion power generation on aircraft, or main battle tanks. The concept uses controlled motion of electrically charged matter through accelerated vibration and/or accelerated spin subjected to smooth, yet rapid acceleration transients, to generate extremely high-energy/high-intensity EM radiation (fields of high-energy photons) which not only confines the plasma but also greatly compresses itso as to produce a high power density plasma burn, leading to ignition. The PCFD concept can produce power in the gigawatt to terawatt range (and higher) with input power in the kilowatt to megawatt range and can possibly lead to ignition (selfsustained) plasma burn. Several important practical engineering and operational issues with operating a device such as the PCFD are discussed.
https://e-catworld.com/2014/02/08/german-article-on-cold-fusion-introduces-new-lenr-company-purratio-ag/
February 8, 2014
German Article on Cold Fusion Introduces New LENR Company — PURRATIO AG
Thanks to Andreas Moraitis, barty, and others for finding an article published by the German Focus magazine about the current state of play in the world of fusion energy (it discusses both cold and hot versions).
In the area of CF/LENR, the author, Michael Odenwald, mentions Andrea Rossi and the E-Cat, but also introduces a German company called PURRATIO AG which has apparently developed (or is developing) a reactor made of palladium (a hollow tube, a few inches long) which is designed to absorb hydrogen. The reaction occurs when an electrical charge is passed through the reactor.
There’s a document on the PURRATIO website which describes the reaction. It announces this technology as “The most revolutionary, most meaningful and most innovative technology – the „COLD FUSION“”, and explains:
The experimental procedure is carried out by means of an especially developed prototype on laboratory scale.
The neutron signal is reproducible and a doubtless proof of a neutron generating nuclear process in the described experiment.
A generation of the detector signal by perturbing influences of electronic origin can absolutely be ruled out.
The crucial physical parameters for the realization of the fusion effect are known. By appropriate changing of these parameters the fusion effect can be amplified up to the generation of excess heat or the generation of an explosion effect.
It’s interesting to discover a brand new player in the cold fusion field — this is a company that I have never heard mentioned before. A brief perusal of their website shows that they have been around for quite a long time working in the field of nanotechnology, and it seems that branching out into the world of cold fusion is a relatively recent development. Here’s another player to keep an eye on!
US8129656Inventor: REICHMANN RICHARD / BARTH KARL-LUDWIG [DE]
METHOD FOR PRODUCING THERMAL ENERGY
Applicant: PURRATIO AG [DE]
The invention relates to a method for producing thermal energy, wherein light, initial material is introduced into a plasma arc which is located between a cathode and an anode and which is adapted to fusion processes by supplying electric energy into the plasma state. A metal cathode, which allows particles which are produced in the plasma to be diffused, is used and allows a fusion process to take place in the metal grid. The invention has a high degree of efficiency in corresponding systems such that said method can be used anywhere where fossils and/or renewable and/or chemical fuel can be used, as to use the thermal energy directly or by conversion.
http://truthstreammedia.com/2014/12/13/1625/
A Century Ago: Rockefellers Funded Eugenics Initiative to Sterilize 15 Million Americans
https://www.sciencedirect.com/science/article/pii/S0048969720301200
Science of The Total Environment, 22 January 2020, 136610
https://doi.org/10.1016/j.scitotenv.2020.136610
Exoskeleton dissolution with mechanoreceptor damage in larval Dungeness crab related to severity of present-day ocean acidification vertical gradientsHighlights
Nina Bednaršek, et al.
Coastal habitats with the steepest ocean acidification gradients are most detrimental for larval Dungeness crabs.
Severe carapace dissolution was observed in larval Dungeness crabs along the US west coast.
Mechanoreceptors with important sensory and behavioral functions were destabilized.
Dissolution is negatively related to the growth, demonstrating energetic trade-offs.
10% dissolution increase over the last two decades estimated due to atmospheric CO2.
https://usdebtclock.org/
The US Debt Clock
https://news.harvard.edu/gazette/story/2020/01/harvard-researchers-find-ways-to-improve-on-soap-and-water/
Harvard Chan Center for Nanotechnology and Nanotoxicology looks to improve on soap and water
WO2016044443A1
ENGINEERED WATER NANOSTRUCTURES (EWNS) AND USES THEREOF
Various embodiments of the present invention relate to, among other things, systems for generating engineered water nanostructures (EWNS) comprising reactive oxygen species (ROS) and methods for inactivating at least one of viruses, bacteria, bacterial spores, and fungi in or on a wound of a subject in need thereof or on produce by applying EWNS to the wound or to the produce.
https://www.sciencedaily.com/releases/2020/01/200122080509.htm
January 22, 2020
Researchers find a new set of geometric motifs that can create self-locking, lightweight, durable structures out of soft materials. The kirigami-inspired designs can support 14,000 times their weight and, because they don't require adhesives or fasteners, can easily be flattened and re-folded.
https://journals.aps.org/prx/abstract/10.1103/PhysRevX.10.011013
Phys. Rev. X 10, 011013
21 January 2020
Keeping It Together: Interleaved Kirigami Extension AssemblyAbstract
Xinyu Wang, Simon D. Guest, and Randall D. Kamien
Traditional origami structures can be continuously deformed back to a flat sheet of paper, while traditional kirigami requires glue or seams in order to maintain its rigidity. In the former, nontrivial geometry can be created through overfolding paper, while in the latter, the paper topology is modified. Here we propose a hybrid approach that relies on overlapped flaps that create in-plane compression resulting in the formation of polyhedra composed of freely supported plates. Not only are these structures self-locking, but they have colossal load-to-weight ratios of order 104.
https://www.rmit.edu.au/news/media-releases-and-expert-comments/2020/jan/bacteria-liquid-metal
Bacteria shredding tech to fight drug-resistant superbugs
Researchers have used liquid metals to develop new bacteria-destroying technology that could be the answer to the deadly problem of antibiotic resistance.
The technology uses nano-sized particles of magnetic liquid metal to shred bacteria and bacterial biofilm – the protective “house” that bacteria thrive in – without harming good cells.
Published in ACS Nano, the research led by RMIT University offers a groundbreaking new direction in the search for better bacteria-fighting technologies.
Antibiotic resistance is a major global health threat, causing at least 700,000 deaths a year. Without action, the death toll could rise to 10 million people a year by 2050, overtaking cancer as a cause of death.
The biggest issues are the spread of dangerous, drug-resistant superbugs and the growth of bacterial biofilm infections, which can no longer be treated with existing antibiotics.
Dr Aaron Elbourne said antibiotics had revolutionised health since they were discovered 90 years ago but were losing effectiveness due to misuse.
“We’re heading to a post-antibiotic future, where common bacterial infections, minor injuries and routine surgeries could once again become deadly,” Elbourne, a Postdoctoral Fellow in the Nanobiotechnology Laboratory at RMIT, said.
“It’s not enough to reduce antibiotic use, we need to completely rethink how we fight bacterial infections.
“Bacteria are incredibly adaptable and over time they develop defences to the chemicals used in antibiotics, but they have no way of dealing with a physical attack.
“Our method uses precision-engineered liquid metals to physically rip bacteria to shreds and
smash through the biofilm where bacteria live and multiply.
“With further development, we hope this technology could be the way to help make antibiotic resistance history.”
Let’s get physical: New way to kill bacteria
The RMIT team behind the technology is the only group in the world investigating the antibacterial potential of magnetic liquid metal nanoparticles.
When exposed to a low-intensity magnetic field, these nano-sized droplets change shape and develop sharp edges
When the droplets are placed in contact with a bacterial biofilm, their movements and nano-sharp edges break down the biofilm and physically rupture the bacterial cells.
In the new study, the team tested the effectiveness of the technology against two types of bacterial biofilms (Gram-positive and Gram-negative).
After 90 minutes of exposure to the liquid metal nanoparticles, both biofilms were destroyed and 99% of the bacteria were dead. Importantly, laboratory tests showed the bacteria-destroying droplets did not affect human cells.
Postdoctoral Fellow Dr Vi Khanh Truong said the versatile technology could one day be used in a range of ways to treat infections.
“It could be used as a spray coating for implants, to make them powerfully antibacterial and reduce the high rates of infection for procedures like hip and knee replacements,” said Truong, currently at North Carolina State University on a Fulbright Scholarship to further the research.
“There’s also potential to develop this into an injectable treatment that could be used at the site of infection.”
The next stage for the research - testing the effectiveness of the technology in pre-clinical animal trials - is already underway, with the team hoping to move to clinical human trials in coming years.
Led by Truong, Elbourne and Dr James Chapman, the multi-disciplinary team is also planning to expand the technology beyond antibacterial treatment, exploring how it could be used to:
treat fungal infections - the next superbugs
break through cholesterol plaques and battle heart problems
stop tumours by being injected directly into cancer cells.
ACS Nano 2020, 14, 1, 802-817, January 10, 2020
https://doi.org/10.1021/acsnano.9b07861
Antibacterial Liquid Metals: Biofilm Treatment via Magnetic ActivationAbstract
Aaron Elbourne, et al.
Antibiotic resistance has made the treatment of biofilm-related infections challenging. As such, the quest for next-generation antimicrobial technologies must focus on targeted therapies to which pathogenic bacteria cannot develop resistance. Stimuli-responsive therapies represent an alternative technological focus due to their capability of delivering targeted treatment. This study provides a proof-of-concept investigation into the use of magneto-responsive gallium-based liquid metal (LM) droplets as antibacterial materials, which can physically damage, disintegrate, and kill pathogens within a mature biofilm. Once exposed to a low-intensity rotating magnetic field, the LM droplets become physically actuated and transform their shape, developing sharp edges. When placed in contact with a bacterial biofilm, the movement of the particles resulting from the magnetic field, coupled with the presence of nanosharp edges, physically ruptures the bacterial cells and the dense biofilm matrix is broken down. The antibacterial efficacy of the magnetically activated LM particles was assessed against both Gram-positive and Gram-negative bacterial biofilms. After 90 min over 99% of both bacterial species became nonviable, and the destruction of the biofilms was observed. These results will impact the design of next-generation, LM-based biofilm treatments.
http://news.rice.edu/2020/01/27/rice-lab-turns-trash-into-valuable-graphene-in-a-flash-2/
Lab turns trash into valuable graphene in a flash
'Green' process promises pristine graphene in bulk using waste food, plastic and other materials
That banana peel, turned into graphene, can help facilitate a massive reduction of the environmental impact of concrete and other building materials. While you're at it, toss in those plastic empties.
A new process introduced by the Rice University lab of chemist James Tour can turn bulk quantities of just about any carbon source into valuable graphene flakes. The process is quick and cheap; Tour said the "flash graphene" technique can convert a ton of coal, food waste or plastic into graphene for a fraction of the cost used by other bulk graphene-producing methods.
"This is a big deal," Tour said. "The world throws out 30% to 40% of all food, because it goes bad, and plastic waste is of worldwide concern. We've already proven that any solid carbon-based matter, including mixed plastic waste and rubber tires, can be turned into graphene."
As reported in Nature, flash graphene is made in 10 milliseconds by heating carbon-containing materials to 3,000 Kelvin (about 5,000 degrees Fahrenheit). The source material can be nearly anything with carbon content. Food waste, plastic waste, petroleum coke, coal, wood clippings and biochar are prime candidates, Tour said. "With the present commercial price of graphene being $67,000 to $200,000 per ton, the prospects for this process look superb," he said.
Tour said a concentration of as little as 0.1% of flash graphene in the cement used to bind concrete could lessen its massive environmental impact by a third. Production of cement reportedly emits as much as 8% of human-made carbon dioxide every year.
"By strengthening concrete with graphene, we could use less concrete for building, and it would cost less to manufacture and less to transport," he said. "Essentially, we're trapping greenhouse gases like carbon dioxide and methane that waste food would have emitted in landfills. We are converting those carbons into graphene and adding that graphene to concrete, thereby lowering the amount of carbon dioxide generated in concrete manufacture. It's a win-win environmental scenario using graphene."
"Turning trash to treasure is key to the circular economy," said co-corresponding author Rouzbeh Shahsavari, an adjunct assistant professor of civil and environmental engineering and of materials science and nanoengineering at Rice and president of C-Crete Technologies. "Here, graphene acts both as a 2D template and a reinforcing agent that controls cement hydration and subsequent strength development."
In the past, Tour said, "graphene has been too expensive to use in these applications. The flash process will greatly lessen the price while it helps us better manage waste."
"With our method, that carbon becomes fixed," he said. "It will not enter the air again."
The process aligns nicely with Rice's recently announced Carbon Hub initiative to create a zero-emissions future that repurposes hydrocarbons from oil and gas to generate hydrogen gas and solid carbon with zero emission of carbon dioxide. The flash graphene process can convert that solid carbon into graphene for concrete, asphalt, buildings, cars, clothing and more, Tour said.
Flash Joule heating for bulk graphene, developed in the Tour lab by Rice graduate student and lead author Duy Luong, improves upon techniques like exfoliation from graphite and chemical vapor deposition on a metal foil that require much more effort and cost to produce just a little graphene.
Even better, the process produces "turbostratic" graphene, with misaligned layers that are easy to separate. "A-B stacked graphene from other processes, like exfoliation of graphite, is very hard to pull apart," Tour said. "The layers adhere strongly together.
But turbostratic graphene is much easier to work with because the adhesion between layers is much lower. They just come apart in solution or upon blending in composites.
"That's important, because now we can get each of these single-atomic layers to interact with a host composite," he said.
The lab noted that used coffee grounds transformed into pristine single-layer sheets of graphene.
Bulk composites of graphene with plastic, metals, plywood, concrete and other building materials would be a major market for flash graphene, according to the researchers, who are already testing graphene-enhanced concrete and plastic.
The flash process happens in a custom-designed reactor that heats material quickly and emits all noncarbon elements as gas. "When this process is industrialized, elements like oxygen and nitrogen that exit the flash reactor can all be trapped as small molecules because they have value," Tour said.
He said the flash process produces very little excess heat, channeling almost all of its energy into the target. "You can put your finger right on the container a few seconds afterwards," Tour said. "And keep in mind this is almost three times hotter than the chemical vapor deposition furnaces we formerly used to make graphene, but in the flash process the heat is concentrated in the carbon material and none in a surrounding reactor.
"All the excess energy comes out as light, in a very bright flash, and because there aren't any solvents, it's a super clean process," he said.
Luong did not expect to find graphene when he fired up the first small-scale device to find new phases of material, beginning with a sample of carbon black. "This started when I took a look at a Science paper talking about flash Joule heating to make phase-changing nanoparticles of metals," he said. But Luong quickly realized the process produced nothing but high-quality graphene.
Atom-level simulations by Rice researcher and co-author Ksenia Bets confirmed that temperature is key to the material's rapid formation. "We essentially speed up the slow geological process by which carbon evolves into its ground state, graphite," she said. "Greatly accelerated by a heat spike, it is also stopped at the right instant, at the graphene stage.
"It is amazing how state-of-the-art computer simulations, notoriously slow for observing such kinetics, reveal the details of high temperature-modulated atomic movements and transformation," Bets said.
Tour hopes to produce a kilogram (2.2 pounds) a day of flash graphene within two years, starting with a project recently funded by the Department of Energy to convert U.S.-sourced coal. "This could provide an outlet for coal in large scale by converting it inexpensively into a much-higher-value building material," he said.
https://www.youtube.com/watch?v=GzDrnoGdLO4&feature=youtu.be
Rice lab makes pristine graphene in a flash
A new process introduced in Nature by the Rice University lab of chemist James Tour can turn bulk quantities of just about any carbon source into valuable graphene flakes. The process is quick and cheap; Tour said the "flash graphene" technique can convert a ton of coal, food waste or plastic into graphene for about $100 in electricity costs.
WO2018085789A1Abstract
METHODS OF FABRICATING LASER-INDUCED GRAPHENE AND COMPOSITIONS THEREOF
Methods that expand the properties of laser-induced graphene (LIG) and the resulting LIG having the expanded properties. Methods of fabricating laser-induced graphene from materials, which range from natural, renewable precursors (such as cloth or paper) to high performance polymers (like Kevlar). With multiple lasing, however, highly conductive PEI- based LIG could be obtained using both multiple pass and defocus methods. The resulting laser-induced graphene can be used, inter alia, in electronic devices, as antifouling surfaces, in water treatment technology, in membranes, and in electronics on paper and food Such methods include fabrication of LIG in controlled atmospheres, such that, for example, superhydrophobic and superhydrophilic LIG surfaces can be obtained. Such methods further include fabricating laser-induced graphene by multiple lasing of carbon precursors.
US10505193B2Abstract
Laser induced graphene materials and their use in electronic devices
In some embodiments, the present disclosure pertains to methods of producing a graphene material by exposing a polymer to a laser source. I
https://news.harvard.edu/gazette/story/2020/01/harvard-researchers-find-ways-to-improve-on-soap-and-water/
Harvard Chan Center for Nanotechnology and Nanotoxicology looks to improve on soap and water
WO2016044443A1
ENGINEERED WATER NANOSTRUCTURES (EWNS) AND USES THEREOF
Various embodiments of the present invention relate to, among other things, systems for generating engineered water nanostructures (EWNS) comprising reactive oxygen species (ROS) and methods for inactivating at least one of viruses, bacteria, bacterial spores, and fungi in or on a wound of a subject in need thereof or on produce by applying EWNS to the wound or to the produce.
https://www.sciencedaily.com/releases/2020/01/200122080509.htm
January 22, 2020
Researchers find a new set of geometric motifs that can create self-locking, lightweight, durable structures out of soft materials. The kirigami-inspired designs can support 14,000 times their weight and, because they don't require adhesives or fasteners, can easily be flattened and re-folded.
https://journals.aps.org/prx/abstract/10.1103/PhysRevX.10.011013
Phys. Rev. X 10, 011013, 21 January 2020
Keeping It Together: Interleaved Kirigami Extension AssemblyAbstract
Xinyu Wang, Simon D. Guest, and Randall D. Kamien
Traditional origami structures can be continuously deformed back to a flat sheet of paper, while traditional kirigami requires glue or seams in order to maintain its rigidity. In the former, nontrivial geometry can be created through overfolding paper, while in the latter, the paper topology is modified. Here we propose a hybrid approach that relies on overlapped flaps that create in-plane compression resulting in the formation of polyhedra composed of freely supported plates. Not only are these structures self-locking, but they have colossal load-to-weight ratios of order 104.
https://www.sciencedaily.com/releases/2014/02/140227142250.htm
February 27, 2014
Deadly immune 'storm' caused by emergent flu infections
https://www.pnas.org/content/111/10/3799
Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection
John R. Teijaro, et al.
https://www.rmit.edu.au/news/media-releases-and-expert-comments/2020/jan/bacteria-liquid-metal
Bacteria shredding tech to fight drug-resistant superbugs
Researchers have used liquid metals to develop new bacteria-destroying technology that could be the answer to the deadly problem of antibiotic resistance.
The technology uses nano-sized particles of magnetic liquid metal to shred bacteria and bacterial biofilm – the protective “house” that bacteria thrive in – without harming good cells.
Published in ACS Nano, the research led by RMIT University offers a groundbreaking new direction in the search for better bacteria-fighting technologies.
Antibiotic resistance is a major global health threat, causing at least 700,000 deaths a year. Without action, the death toll could rise to 10 million people a year by 2050, overtaking cancer as a cause of death.
The biggest issues are the spread of dangerous, drug-resistant superbugs and the growth of bacterial biofilm infections, which can no longer be treated with existing antibiotics.
Dr Aaron Elbourne said antibiotics had revolutionised health since they were discovered 90 years ago but were losing effectiveness due to misuse.
“We’re heading to a post-antibiotic future, where common bacterial infections, minor injuries and routine surgeries could once again become deadly,” Elbourne, a Postdoctoral Fellow in the Nanobiotechnology Laboratory at RMIT, said.
“It’s not enough to reduce antibiotic use, we need to completely rethink how we fight bacterial infections.
“Bacteria are incredibly adaptable and over time they develop defences to the chemicals used in antibiotics, but they have no way of dealing with a physical attack.
“Our method uses precision-engineered liquid metals to physically rip bacteria to shreds and
smash through the biofilm where bacteria live and multiply.
“With further development, we hope this technology could be the way to help make antibiotic resistance history.”
Let’s get physical: New way to kill bacteria
The RMIT team behind the technology is the only group in the world investigating the antibacterial potential of magnetic liquid metal nanoparticles.
When exposed to a low-intensity magnetic field, these nano-sized droplets change shape and develop sharp edges
When the droplets are placed in contact with a bacterial biofilm, their movements and nano-sharp edges break down the biofilm and physically rupture the bacterial cells.
In the new study, the team tested the effectiveness of the technology against two types of bacterial biofilms (Gram-positive and Gram-negative).
After 90 minutes of exposure to the liquid metal nanoparticles, both biofilms were destroyed and 99% of the bacteria were dead. Importantly, laboratory tests showed the bacteria-destroying droplets did not affect human cells.
Postdoctoral Fellow Dr Vi Khanh Truong said the versatile technology could one day be used in a range of ways to treat infections.
“It could be used as a spray coating for implants, to make them powerfully antibacterial and reduce the high rates of infection for procedures like hip and knee replacements,” said Truong, currently at North Carolina State University on a Fulbright Scholarship to further the research.
“There’s also potential to develop this into an injectable treatment that could be used at the site of infection.”
The next stage for the research - testing the effectiveness of the technology in pre-clinical animal trials - is already underway, with the team hoping to move to clinical human trials in coming years.
Led by Truong, Elbourne and Dr James Chapman, the multi-disciplinary team is also planning to expand the technology beyond antibacterial treatment, exploring how it could be used to:
treat fungal infections - the next superbugs
break through cholesterol plaques and battle heart problems
stop tumours by being injected directly into cancer cells.
ACS Nano 2020, 14, 1, 802-817, January 10, 2020
https://doi.org/10.1021/acsnano.9b07861
Antibacterial Liquid Metals: Biofilm Treatment via Magnetic ActivationAbstract
Aaron Elbourne, et al.
Antibiotic resistance has made the treatment of biofilm-related infections challenging. As such, the quest for next-generation antimicrobial technologies must focus on targeted therapies to which pathogenic bacteria cannot develop resistance. Stimuli-responsive therapies represent an alternative technological focus due to their capability of delivering targeted treatment. This study provides a proof-of-concept investigation into the use of magneto-responsive gallium-based liquid metal (LM) droplets as antibacterial materials, which can physically damage, disintegrate, and kill pathogens within a mature biofilm. Once exposed to a low-intensity rotating magnetic field, the LM droplets become physically actuated and transform their shape, developing sharp edges. When placed in contact with a bacterial biofilm, the movement of the particles resulting from the magnetic field, coupled with the presence of nanosharp edges, physically ruptures the bacterial cells and the dense biofilm matrix is broken down. The antibacterial efficacy of the magnetically activated LM particles was assessed against both Gram-positive and Gram-negative bacterial biofilms. After 90 min over 99% of both bacterial species became nonviable, and the destruction of the biofilms was observed. These results will impact the design of next-generation, LM-based biofilm treatments.
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